INDICATIONS AND CLINICAL USE
DDAVP injection is indicated for prophylaxis of mild hemophilia A and mild von Willebrand’s
disease Type I, and for the treatment of central diabetes insipidus.
Hemophilia A
DDAVP injection is indicated for patients with hemophilia A with Factor VIII levels greater than
5%.
DDAVP will often maintain hemostasis in patients with hemophilia A during surgical
procedures and postoperatively, when administered 45 minutes prior to the scheduled procedure.
DDAVP will also stop bleeding in hemophilia A patients with episodes of spontaneous or
trauma-induced injuries such as hemarthroses, intramuscular hematomas or mucosal bleeding.
In certain clinical situations, it may be justified to try DDAVP in patients with Factor VIII levels
between 2-5%, however, these patients should be carefully monitored.
Von Willebrand’s Disease (Type I)
DDAVP injection is indicated for patients with mild to moderate classic von Willebrand’s
Disease (Type I) with Factor VIII levels greater than 5%.
DDAVP will often maintain hemostasis in surgical procedures and postoperatively when
administered 45 minutes prior to the scheduled procedure.
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https://pdf.hres.ca/dpd_pm/00044657.PDF
PM date: April 5, 2017
Source product: DDAVP INJ 4MCG/ML; DIN 00873993; fetched 2026-09-10
Product monograph posted by Health Canada; excerpt for lookup only.