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Lowest DBP recovery rule under medically necessary no-substitution claims: 6.2 Medically Necessary "No Substitution" Claims The Side Effect Reporting Form will not have to be renewed. However, the pharmacy must maintain a copy of the prescription that contains a direction that there be no substitution and the required Health Canada Side Effect Reporting Form (completed and signed by the prescriber). The prescriber must write “No Substitution” or “No Sub” on renewal or subsequent new written prescriptions, and indicate “No Substitution” on subsequent new oral prescriptions. The dispenser will be reimbursed the DBP plus a mark-up and the lesser of the posted usual and customary fee or the ODB dispensing fee minus the applicable ODB co-payment amount. Where a completed Side Effect Reporting Form is not available at the pharmacy during an inspection, the difference between the cost of the higher-cost product and the lowest DBP listed for the interchangeable category will be recovered. (ontario.ca, Revision #17; 2026-08-03 ↗) 6.2 Medically Necessary "No Substitution" Claims The Ministry will provide reimbursement of a higher-cost interchangeable product in medically necessary circumstances where a patient has experienced a significant adverse reaction with two (2) lower-cost interchangeable drug products, where available. When a prescriber identifies a patient for which it is medically necessary that a higher cost interchangeable product be provided, the prescriber must: • Complete, sign and forward to the pharmacist a copy of the Health Canada side effect reporting form for each lower-cost interchangeable drug product trialed (Side Effect Reporting Form[s]); and • Write “No Substitution” or “No Sub” on a written prescription or indicate “No Substitution” to the pharmacist in the case of a verbal prescription. The prescriber should keep a copy of the completed form in the patient’s record for future use and reference. In the case of a written prescription, when the pharmacist or dispensing physician receives a prescription with the written notation “No Substitution” or “No Sub”, reimbursement will be provided for the higher-cost interchangeable product only if the prescription is accompanied by a completed Health Canada Side Effect Reporting Form for each of the lower-cost interchangeable drug products trialed. This form must be completely filled out noting the details of the adverse reaction and signed by the prescriber. In the case of a verbal prescription, the prescriber must satisfy the operator of the pharmacy or dispensing physician that a completed Health Canada Side Effect Reporting Form for each of the lower-cost interchangeable drug products trialed has been completed and signed by the prescriber. A written record of this verbal prescription and the completed Health Canada Side Effect Reporting Form must be received by the pharmacy prior to claim submission. Upon receipt, the pharmacist must: • Fax, submit online or mail the completed and signed form to Health Canada’s Canada Vigilance Program; and • Retain his or her copy of the completed and signed Side Effect Reporting Form. (ontario.ca, Revision #17; 2026-08-03 ↗)

Sandoz Metformin FC · DIN 02246820 Manufacturer: Sandoz Canada Inc.; listing date 2003-09-04 Health Canada: Marketed since 2006-01-12 · brand SANDOZ METFORMIN FC · ATC A10BA02 METFORMIN · form Tablet · route Oral · ingredients METFORMIN HYDROCHLORIDE 500 MG · company Sandoz canada incorporated · schedule Prescription

DIN 02246820: Sandoz Metformin FC Raw flags: chronicUseMed=Y, insOH=Y, sec3=Y Item: 682002008; group id 750; item number 1837; lccId None; manufacturer id SDZ Source form: Tab; strength: 500mg Recorded listing: General benefit; chronic-use medication (100-day supply rule, dispensing-fee limit); diabetes medication flag Source prices (unrounded): $0.0247; ministry $0.0247 Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02246820 Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=71020

Interchangeable products

Apo-Metformin · DIN 02167786 · $0.0247 Auro-Metformin · DIN 02438275 · $0.0247 Glucophage · DIN 02099233 · $0.0247 Jamp-Metformin · DIN 02380196 · $0.0247 M-Metformin · DIN 02547767 · $0.0247 Mar-Metformin · DIN 02378620 · $0.0247 Metformin · DIN 02353377 · $0.0247 Metformin FC · DIN 02385341 · $0.0247 Mint-Metformin · DIN 02388766 · $0.0247 NRA-Metformin · DIN 02536439 · $0.0247 Novo-Metformin · DIN 02045710 · $0.0247 PMS-Metformin · DIN 02223562 · $0.0247 PMSC-Metformin · DIN 02520303 · $0.0247 PRZ-Metformin · DIN 02531895 · $0.0247 Ran-Metformin · DIN 02269031 · $0.0247 Ratio-Metformin · DIN 02242974 · $0.0247 Septa-Metformin · DIN 02379767 · $0.0247 Teva-Metformin · DIN 02257726 · $0.0247

Shortage status: not checked (no credentials)