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Lowest DBP recovery rule under medically necessary no-substitution claims: 6.2 Medically Necessary "No Substitution" Claims The Side Effect Reporting Form will not have to be renewed. However, the pharmacy must maintain a copy of the prescription that contains a direction that there be no substitution and the required Health Canada Side Effect Reporting Form (completed and signed by the prescriber). The prescriber must write “No Substitution” or “No Sub” on renewal or subsequent new written prescriptions, and indicate “No Substitution” on subsequent new oral prescriptions. The dispenser will be reimbursed the DBP plus a mark-up and the lesser of the posted usual and customary fee or the ODB dispensing fee minus the applicable ODB co-payment amount. Where a completed Side Effect Reporting Form is not available at the pharmacy during an inspection, the difference between the cost of the higher-cost product and the lowest DBP listed for the interchangeable category will be recovered. (ontario.ca, Revision #17; 2026-08-03 ↗) 6.2 Medically Necessary "No Substitution" Claims The Ministry will provide reimbursement of a higher-cost interchangeable product in medically necessary circumstances where a patient has experienced a significant adverse reaction with two (2) lower-cost interchangeable drug products, where available. When a prescriber identifies a patient for which it is medically necessary that a higher cost interchangeable product be provided, the prescriber must: • Complete, sign and forward to the pharmacist a copy of the Health Canada side effect reporting form for each lower-cost interchangeable drug product trialed (Side Effect Reporting Form[s]); and • Write “No Substitution” or “No Sub” on a written prescription or indicate “No Substitution” to the pharmacist in the case of a verbal prescription. The prescriber should keep a copy of the completed form in the patient’s record for future use and reference. In the case of a written prescription, when the pharmacist or dispensing physician receives a prescription with the written notation “No Substitution” or “No Sub”, reimbursement will be provided for the higher-cost interchangeable product only if the prescription is accompanied by a completed Health Canada Side Effect Reporting Form for each of the lower-cost interchangeable drug products trialed. This form must be completely filled out noting the details of the adverse reaction and signed by the prescriber. In the case of a verbal prescription, the prescriber must satisfy the operator of the pharmacy or dispensing physician that a completed Health Canada Side Effect Reporting Form for each of the lower-cost interchangeable drug products trialed has been completed and signed by the prescriber. A written record of this verbal prescription and the completed Health Canada Side Effect Reporting Form must be received by the pharmacy prior to claim submission. Upon receipt, the pharmacist must: • Fax, submit online or mail the completed and signed form to Health Canada’s Canada Vigilance Program; and • Retain his or her copy of the completed and signed Side Effect Reporting Form. (ontario.ca, Revision #17; 2026-08-03 ↗)

PMS-Paroxetine · DIN 02247751 Manufacturer: Pharmascience Inc.; listing date 2004-04-06 Health Canada: Marketed since 2003-10-29 · brand PMS-PAROXETINE · ATC N06AB05 PAROXETINE · form Tablet · route Oral · ingredients PAROXETINE (PAROXETINE HYDROCHLORIDE) 20 MG · company Pharmascience inc · schedule Prescription

DIN 02247751: PMS-Paroxetine Raw flags: sec3=Y Item: 281604078; group id 467; item number 1176; lccId None; manufacturer id PMS Source form: Tab; strength: 20mg Recorded listing: General benefit Source prices (unrounded): $0.3250; ministry $0.3250 Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02247751 Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=72043

Interchangeable products

AG-Paroxetine · DIN 02475545 · $0.3250 Apo-Paroxetine · DIN 02240908 · $0.3250 Auro-Paroxetine · DIN 02383284 · $0.3250 Co Paroxetine · DIN 02262754 · $0.3250 Jamp Paroxetine Tablets · DIN 02507781 · $0.3250 Jamp-Paroxetine · DIN 02368870 · $0.3250 M-Paroxetine · DIN 02467410 · $0.3250 Mar-Paroxetine · DIN 02411954 · $0.3250 Mint-Paroxetine · DIN 02421380 · $0.3250 NRA-Paroxetine · DIN 02479761 · $0.3250 Paroxetine · DIN 02282852 · $0.3250 Paroxetine · DIN 02388235 · $0.3250 Paxil · DIN 01940481 · $0.3250 Sandoz Paroxetine Tablets · DIN 02431785 · $0.3250 Teva-Paroxetine · DIN 02248557 · $0.3250

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