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Lowest DBP recovery rule under medically necessary no-substitution claims: 6.2 Medically Necessary "No Substitution" Claims The Side Effect Reporting Form will not have to be renewed. However, the pharmacy must maintain a copy of the prescription that contains a direction that there be no substitution and the required Health Canada Side Effect Reporting Form (completed and signed by the prescriber). The prescriber must write “No Substitution” or “No Sub” on renewal or subsequent new written prescriptions, and indicate “No Substitution” on subsequent new oral prescriptions. The dispenser will be reimbursed the DBP plus a mark-up and the lesser of the posted usual and customary fee or the ODB dispensing fee minus the applicable ODB co-payment amount. Where a completed Side Effect Reporting Form is not available at the pharmacy during an inspection, the difference between the cost of the higher-cost product and the lowest DBP listed for the interchangeable category will be recovered. (ontario.ca, Revision #17; 2026-08-03 ↗) 6.2 Medically Necessary "No Substitution" Claims The Ministry will provide reimbursement of a higher-cost interchangeable product in medically necessary circumstances where a patient has experienced a significant adverse reaction with two (2) lower-cost interchangeable drug products, where available. When a prescriber identifies a patient for which it is medically necessary that a higher cost interchangeable product be provided, the prescriber must: • Complete, sign and forward to the pharmacist a copy of the Health Canada side effect reporting form for each lower-cost interchangeable drug product trialed (Side Effect Reporting Form[s]); and • Write “No Substitution” or “No Sub” on a written prescription or indicate “No Substitution” to the pharmacist in the case of a verbal prescription. The prescriber should keep a copy of the completed form in the patient’s record for future use and reference. In the case of a written prescription, when the pharmacist or dispensing physician receives a prescription with the written notation “No Substitution” or “No Sub”, reimbursement will be provided for the higher-cost interchangeable product only if the prescription is accompanied by a completed Health Canada Side Effect Reporting Form for each of the lower-cost interchangeable drug products trialed. This form must be completely filled out noting the details of the adverse reaction and signed by the prescriber. In the case of a verbal prescription, the prescriber must satisfy the operator of the pharmacy or dispensing physician that a completed Health Canada Side Effect Reporting Form for each of the lower-cost interchangeable drug products trialed has been completed and signed by the prescriber. A written record of this verbal prescription and the completed Health Canada Side Effect Reporting Form must be received by the pharmacy prior to claim submission. Upon receipt, the pharmacist must: • Fax, submit online or mail the completed and signed form to Health Canada’s Canada Vigilance Program; and • Retain his or her copy of the completed and signed Side Effect Reporting Form. (ontario.ca, Revision #17; 2026-08-03 ↗)

Pharma-Simvastatin · DIN 02469987 Manufacturer: Pharmascience Inc.; listing date 2018-04-30 Health Canada: Marketed since 2017-11-29 · brand PHARMA-SIMVASTATIN · ATC C10AA01 SIMVASTATIN · form Tablet · route Oral · ingredients SIMVASTATIN 10 MG · company Pharmascience inc · schedule Prescription

DIN 02469987: Pharma-Simvastatin Raw flags: chronicUseMed=Y, sec3=Y Item: 240600016; group id 309; item number 0679; lccId None; manufacturer id PMS Source form: Tab; strength: 10mg Recorded listing: General benefit; chronic-use medication (100-day supply rule, dispensing-fee limit) Source prices (unrounded): $0.2023; ministry $0.2023 Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02469987 Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=95893

Interchangeable products

AG-Simvastatin · DIN 02480069 · $0.2023 Apo-Simvastatin · DIN 02247012 · $0.2023 Auro-Simvastatin · DIN 02405156 · $0.2023 Co Simvastatin · DIN 02248104 · $0.2023 Jamp-Simvastatin · DIN 02375605 · $0.2023 Mar-Simvastatin · DIN 02375044 · $0.2023 Mint-Simvastatin · DIN 02372940 · $0.2023 PMSC-Simvastatin · DIN 02549646 · $0.2023 Ran-Simvastatin · DIN 02329158 · $0.2023 Simvastatin · DIN 02284731 · $0.2023 Simvastatin · DIN 02386305 · $0.2023 Taro-Simvastatin · DIN 02265885 · not recorded Teva-Simvastatin · DIN 02250152 · $0.2023 Zocor · DIN 00884332 · $0.2023

Shortage status: not checked (no credentials)