ALMOTRIPTAN
All products: not a benefit
Other products in the same Health Canada class (N02CC) — coverage varies; not interchangeable
- Eletriptan (Relpax): not a benefit
- Frovatriptan (Frova): not a benefit
- Naratriptan (Amerge): not a benefit
- Rizatriptan (Maxalt RPD): not a benefit
- Sumatriptan (Imitrex): not a benefit
- Zolmitriptan (Zomig Rapimelt): not a benefit
1 more in the class list below
Mylan-Almotriptan · DIN 02398435 · 6.25mg · tablet
Off-Formulary Interchangeable, not an ODB benefitMarketed · checked 2026-09-02
StatusOff-Formulary Interchangeable, not an ODB benefit
Write on scriptnot a benefit; no Exceptional Access criteria on record; see alternatives
Patient paysPatient pays: program not supplied; amount cannot be determined.
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Ministry criteria list dated January 1, 2025; the program's current criteria may differ; SADIE shows the current version. Current criteria in SADIE
Coverage criteria
Exceptional Access criteria on record are for Brand(s): Axert; DOSAGE FORM/ STRENGTH: 6 mg, 12.5mg tablet — not this product; no criteria on record for this product in this block.
Exceptional Access Program criteria on record (ministry list dated 2025-01-01, not exhaustive):
Ministry criteria list dated January 1, 2025; the program's current criteria may differ; SADIE shows the current version. https://www.ontario.ca/page/sadie-special-authorization-digital-information-exchange
Almotriptan
Brand(s): Axert
DOSAGE FORM/ STRENGTH: 6 mg, 12.5mg tablet
Naratriptan
Brand(s): Amerge
DOSAGE FORM/ STRENGTH: 1 mg, 2.5 mg tablet
Rizatriptan
Brand(s): Maxalt, Maxalt RPD
DOSAGE FORM/ STRENGTH: 5 mg, 10 mg tablet and wafer
Sumatriptan
Brand(s): Imitrex
DOSAGE FORM/ STRENGTH: 50 mg, 100 mg tablet
For the treatment of migraines with or without aura in patients who failed
adequate trials of other medications for migraines (e.g. acetaminophen, NSAIDs)
and where the following information is provided:
• Details of migraine prophylactic regimens (e.g. amitriptyline, beta-blockers) tried
or rationale why they are inappropriate; and
• The number of attacks, duration, and severity of migraines.
Duration of Approval: 5 years
Renewal requests may be considered for patients who continue to benefit from
treatment. The physician must provide the frequency of triptan use.
Warning: The frequent use of triptans (i.e. more than three days per week for longer
than three months at a time) may predispose a patient to developing triptan-induced
chronic daily headaches.
217
EAP source: eap-frequently-requested-drugs-2025-01-01.txt, page 217, record 124, corpus 2025-01-01; name match only, not an eligibility decision
1 brand, same coverage
Mylan-Almotriptan · DIN 02398435
Manufacturer: Mylan Pharmaceuticals ULC; listing date 2013-09-27
Health Canada: Marketed since 2013-07-22 · brand MYLAN-ALMOTRIPTAN · ATC N02CC05 ALMOTRIPTAN · form Tablet · route Oral · ingredients ALMOTRIPTAN (ALMOTRIPTAN MALATE) 6.25 MG · company Mylan pharmaceuticals ulc · schedule Prescription
Check this DIN again · Health Canada product recordMylan-Almotriptan: Formulary list price $9.7833/unit (unit not stated in source; not the patient's cost)
Ministry pays: $9.7833 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=88339 · Verify on the e-Formulary ↗ (DIN 02398435)
Source record
The source extract's flag for this DIN is unclear — confirm on the e-Formulary before prescribing (DIN 02398435).
DIN 02398435: Mylan-Almotriptan
Raw flags: sec3=Y, sec3b=Y, sec3bEAP=Y
Item: 289200017; group id 534; item number 1443; lccId None; manufacturer id MYL
Source form: Tab; strength: 6.25mg
Recorded listing: Off-Formulary Interchangeable, not an ODB benefit; may be reimbursed through the Exceptional Access Program when approved (likely, unconfirmed)
Source prices (unrounded): $9.7833; ministry $9.7833
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02398435
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=88339
Interchangeable products
Apo-Almotriptan · DIN 02405792 · $9.7833
Axert · DIN 02248128 · not recorded
Shortage status: resolved shortage (ended 2024-03-22); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02398435
Shortage record checked 2026-09-13T08:10:21.292534+00:00
Almotriptan · DIN 02466821 · 12.5mg · tablet
Off-Formulary Interchangeable, not an ODB benefitMarketed · checked 2026-09-02
StatusOff-Formulary Interchangeable, not an ODB benefit
Write on scriptnot a benefit; no Exceptional Access criteria on record; see alternatives
Patient paysPatient pays: program not supplied; amount cannot be determined.
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Ministry criteria list dated January 1, 2025; the program's current criteria may differ; SADIE shows the current version. Current criteria in SADIE
Coverage criteria
Exceptional Access criteria on record are for Brand(s): Axert; DOSAGE FORM/ STRENGTH: 6 mg, 12.5mg tablet — not this product; no criteria on record for this product in this block.
Exceptional Access Program criteria on record (ministry list dated 2025-01-01, not exhaustive):
Ministry criteria list dated January 1, 2025; the program's current criteria may differ; SADIE shows the current version. https://www.ontario.ca/page/sadie-special-authorization-digital-information-exchange
Almotriptan
Brand(s): Axert
DOSAGE FORM/ STRENGTH: 6 mg, 12.5mg tablet
Naratriptan
Brand(s): Amerge
DOSAGE FORM/ STRENGTH: 1 mg, 2.5 mg tablet
Rizatriptan
Brand(s): Maxalt, Maxalt RPD
DOSAGE FORM/ STRENGTH: 5 mg, 10 mg tablet and wafer
Sumatriptan
Brand(s): Imitrex
DOSAGE FORM/ STRENGTH: 50 mg, 100 mg tablet
For the treatment of migraines with or without aura in patients who failed
adequate trials of other medications for migraines (e.g. acetaminophen, NSAIDs)
and where the following information is provided:
• Details of migraine prophylactic regimens (e.g. amitriptyline, beta-blockers) tried
or rationale why they are inappropriate; and
• The number of attacks, duration, and severity of migraines.
Duration of Approval: 5 years
Renewal requests may be considered for patients who continue to benefit from
treatment. The physician must provide the frequency of triptan use.
Warning: The frequent use of triptans (i.e. more than three days per week for longer
than three months at a time) may predispose a patient to developing triptan-induced
chronic daily headaches.
217
EAP source: eap-frequently-requested-drugs-2025-01-01.txt, page 217, record 124, corpus 2025-01-01; name match only, not an eligibility decision
Brand vs generic price
Lowest DBP recovery rule under medically necessary no-substitution claims:
6.2 Medically Necessary "No Substitution" Claims
The Side Effect Reporting Form will not have to be renewed. However, the
pharmacy must maintain a copy of the prescription that contains a direction that
there be no substitution and the required Health Canada Side Effect Reporting Form
(completed and signed by the prescriber). The prescriber must write “No
Substitution” or “No Sub” on renewal or subsequent new written prescriptions, and
indicate “No Substitution” on subsequent new oral prescriptions. The dispenser will
be reimbursed the DBP plus a mark-up and the lesser of the posted usual and
customary fee or the ODB dispensing fee minus the applicable ODB co-payment
amount. Where a completed Side Effect Reporting Form is not available at the
pharmacy during an inspection, the difference between the cost of the higher-cost
product and the lowest DBP listed for the interchangeable category will be
recovered.
(ontario.ca, Revision #17; 2026-08-03 ↗)
6.2 Medically Necessary "No Substitution" Claims
The Ministry will provide reimbursement of a higher-cost interchangeable product in
medically necessary circumstances where a patient has experienced a significant
adverse reaction with two (2) lower-cost interchangeable drug products, where
available. When a prescriber identifies a patient for which it is medically necessary
that a higher cost interchangeable product be provided, the prescriber must:
• Complete, sign and forward to the pharmacist a copy of the Health Canada
side effect reporting form for each lower-cost interchangeable drug product
trialed (Side Effect Reporting Form[s]); and
• Write “No Substitution” or “No Sub” on a written prescription or indicate “No
Substitution” to the pharmacist in the case of a verbal prescription.
The prescriber should keep a copy of the completed form in the patient’s record for
future use and reference.
In the case of a written prescription, when the pharmacist or dispensing physician
receives a prescription with the written notation “No Substitution” or “No Sub”,
reimbursement will be provided for the higher-cost interchangeable product only if
the prescription is accompanied by a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed.
This form must be completely filled out noting the details of the adverse reaction
and signed by the prescriber.
In the case of a verbal prescription, the prescriber must satisfy the operator of the
pharmacy or dispensing physician that a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed
has been completed and signed by the prescriber. A written record of this verbal
prescription and the completed Health Canada Side Effect Reporting Form must be
received by the pharmacy prior to claim submission.
Upon receipt, the pharmacist must:
• Fax, submit online or mail the completed and signed form to Health Canada’s
Canada Vigilance Program; and
• Retain his or her copy of the completed and signed Side Effect Reporting
Form.
(ontario.ca, Revision #17; 2026-08-03 ↗)1 brand, same coverage
Almotriptan · DIN 02466821
Manufacturer: Sanis Health Inc.; listing date 2020-06-30
Health Canada: Marketed since 2018-03-06 · brand ALMOTRIPTAN · ATC N02CC05 ALMOTRIPTAN · form Tablet · route Oral · ingredients ALMOTRIPTAN (ALMOTRIPTAN MALATE) 12.5 MG · company Sanis health inc · schedule Prescription
Check this DIN again · Health Canada product recordAlmotriptan: Formulary list price $9.7833/unit (unit not stated in source; not the patient's cost)
Ministry pays: $9.7833 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=95519 · Verify on the e-Formulary ↗ (DIN 02466821)
Source record
The source extract's flag for this DIN is unclear — confirm on the e-Formulary before prescribing (DIN 02466821).
DIN 02466821: Almotriptan
Raw flags: sec3=Y, sec3b=Y, sec3bEAP=Y
Item: 289200016; group id 534; item number 1444; lccId None; manufacturer id SAI
Source form: Tab; strength: 12.5mg
Recorded listing: Off-Formulary Interchangeable, not an ODB benefit; may be reimbursed through the Exceptional Access Program when approved (likely, unconfirmed)
Source prices (unrounded): $9.7833; ministry $9.7833
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02466821
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=95519
Interchangeable products
Apo-Almotriptan · DIN 02405806 · $9.7833
Axert · DIN 02248129 · not recorded
Mylan-Almotriptan · DIN 02398443 · $9.7833
Sandoz Almotriptan · DIN 02405334 · $9.7825
Teva-Almotriptan · DIN 02434849 · $9.7833
Shortage status: resolved shortage (ended 2019-09-06); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02466821
Shortage record checked 2026-09-13T08:10:21.292534+00:00
Mylan-Almotriptan · DIN 02398443 · 12.5mg · tablet
Off-Formulary Interchangeable, not an ODB benefitMarketed · checked 2026-09-02
StatusOff-Formulary Interchangeable, not an ODB benefit
Write on scriptnot a benefit; no Exceptional Access criteria on record; see alternatives
Patient paysPatient pays: program not supplied; amount cannot be determined.
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Ministry criteria list dated January 1, 2025; the program's current criteria may differ; SADIE shows the current version. Current criteria in SADIE
Coverage criteria
Exceptional Access criteria on record are for Brand(s): Axert; DOSAGE FORM/ STRENGTH: 6 mg, 12.5mg tablet — not this product; no criteria on record for this product in this block.
Exceptional Access Program criteria on record (ministry list dated 2025-01-01, not exhaustive):
Ministry criteria list dated January 1, 2025; the program's current criteria may differ; SADIE shows the current version. https://www.ontario.ca/page/sadie-special-authorization-digital-information-exchange
Almotriptan
Brand(s): Axert
DOSAGE FORM/ STRENGTH: 6 mg, 12.5mg tablet
Naratriptan
Brand(s): Amerge
DOSAGE FORM/ STRENGTH: 1 mg, 2.5 mg tablet
Rizatriptan
Brand(s): Maxalt, Maxalt RPD
DOSAGE FORM/ STRENGTH: 5 mg, 10 mg tablet and wafer
Sumatriptan
Brand(s): Imitrex
DOSAGE FORM/ STRENGTH: 50 mg, 100 mg tablet
For the treatment of migraines with or without aura in patients who failed
adequate trials of other medications for migraines (e.g. acetaminophen, NSAIDs)
and where the following information is provided:
• Details of migraine prophylactic regimens (e.g. amitriptyline, beta-blockers) tried
or rationale why they are inappropriate; and
• The number of attacks, duration, and severity of migraines.
Duration of Approval: 5 years
Renewal requests may be considered for patients who continue to benefit from
treatment. The physician must provide the frequency of triptan use.
Warning: The frequent use of triptans (i.e. more than three days per week for longer
than three months at a time) may predispose a patient to developing triptan-induced
chronic daily headaches.
217
EAP source: eap-frequently-requested-drugs-2025-01-01.txt, page 217, record 124, corpus 2025-01-01; name match only, not an eligibility decision
Brand vs generic price
Lowest DBP recovery rule under medically necessary no-substitution claims:
6.2 Medically Necessary "No Substitution" Claims
The Side Effect Reporting Form will not have to be renewed. However, the
pharmacy must maintain a copy of the prescription that contains a direction that
there be no substitution and the required Health Canada Side Effect Reporting Form
(completed and signed by the prescriber). The prescriber must write “No
Substitution” or “No Sub” on renewal or subsequent new written prescriptions, and
indicate “No Substitution” on subsequent new oral prescriptions. The dispenser will
be reimbursed the DBP plus a mark-up and the lesser of the posted usual and
customary fee or the ODB dispensing fee minus the applicable ODB co-payment
amount. Where a completed Side Effect Reporting Form is not available at the
pharmacy during an inspection, the difference between the cost of the higher-cost
product and the lowest DBP listed for the interchangeable category will be
recovered.
(ontario.ca, Revision #17; 2026-08-03 ↗)
6.2 Medically Necessary "No Substitution" Claims
The Ministry will provide reimbursement of a higher-cost interchangeable product in
medically necessary circumstances where a patient has experienced a significant
adverse reaction with two (2) lower-cost interchangeable drug products, where
available. When a prescriber identifies a patient for which it is medically necessary
that a higher cost interchangeable product be provided, the prescriber must:
• Complete, sign and forward to the pharmacist a copy of the Health Canada
side effect reporting form for each lower-cost interchangeable drug product
trialed (Side Effect Reporting Form[s]); and
• Write “No Substitution” or “No Sub” on a written prescription or indicate “No
Substitution” to the pharmacist in the case of a verbal prescription.
The prescriber should keep a copy of the completed form in the patient’s record for
future use and reference.
In the case of a written prescription, when the pharmacist or dispensing physician
receives a prescription with the written notation “No Substitution” or “No Sub”,
reimbursement will be provided for the higher-cost interchangeable product only if
the prescription is accompanied by a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed.
This form must be completely filled out noting the details of the adverse reaction
and signed by the prescriber.
In the case of a verbal prescription, the prescriber must satisfy the operator of the
pharmacy or dispensing physician that a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed
has been completed and signed by the prescriber. A written record of this verbal
prescription and the completed Health Canada Side Effect Reporting Form must be
received by the pharmacy prior to claim submission.
Upon receipt, the pharmacist must:
• Fax, submit online or mail the completed and signed form to Health Canada’s
Canada Vigilance Program; and
• Retain his or her copy of the completed and signed Side Effect Reporting
Form.
(ontario.ca, Revision #17; 2026-08-03 ↗)1 brand, same coverage
Mylan-Almotriptan · DIN 02398443
Manufacturer: Mylan Pharmaceuticals ULC; listing date 2013-09-27
Health Canada: Marketed since 2013-07-22 · brand MYLAN-ALMOTRIPTAN · ATC N02CC05 ALMOTRIPTAN · form Tablet · route Oral · ingredients ALMOTRIPTAN (ALMOTRIPTAN MALATE) 12.5 MG · company Mylan pharmaceuticals ulc · schedule Prescription
Check this DIN again · Health Canada product recordMylan-Almotriptan: Formulary list price $9.7833/unit (unit not stated in source; not the patient's cost)
Ministry pays: $9.7833 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=88340 · Verify on the e-Formulary ↗ (DIN 02398443)
Source record
The source extract's flag for this DIN is unclear — confirm on the e-Formulary before prescribing (DIN 02398443).
DIN 02398443: Mylan-Almotriptan
Raw flags: sec3=Y, sec3b=Y, sec3bEAP=Y
Item: 289200016; group id 534; item number 1444; lccId None; manufacturer id MYL
Source form: Tab; strength: 12.5mg
Recorded listing: Off-Formulary Interchangeable, not an ODB benefit; may be reimbursed through the Exceptional Access Program when approved (likely, unconfirmed)
Source prices (unrounded): $9.7833; ministry $9.7833
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02398443
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=88340
Interchangeable products
Almotriptan · DIN 02466821 · $9.7833
Apo-Almotriptan · DIN 02405806 · $9.7833
Axert · DIN 02248129 · not recorded
Sandoz Almotriptan · DIN 02405334 · $9.7825
Teva-Almotriptan · DIN 02434849 · $9.7833
Shortage status: anticipated shortage (last updated 2026-09-09); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02398443
Shortage record checked 2026-09-13T08:10:21.292534+00:00
Sandoz Almotriptan · DIN 02405334 · 12.5mg · tablet
Off-Formulary Interchangeable, not an ODB benefitMarketed · checked 2026-09-02
StatusOff-Formulary Interchangeable, not an ODB benefit
Write on scriptnot a benefit; no Exceptional Access criteria on record; see alternatives
Patient paysPatient pays: program not supplied; amount cannot be determined.
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Ministry criteria list dated January 1, 2025; the program's current criteria may differ; SADIE shows the current version. Current criteria in SADIE
Coverage criteria
Exceptional Access criteria on record are for Brand(s): Axert; DOSAGE FORM/ STRENGTH: 6 mg, 12.5mg tablet — not this product; no criteria on record for this product in this block.
Exceptional Access Program criteria on record (ministry list dated 2025-01-01, not exhaustive):
Ministry criteria list dated January 1, 2025; the program's current criteria may differ; SADIE shows the current version. https://www.ontario.ca/page/sadie-special-authorization-digital-information-exchange
Almotriptan
Brand(s): Axert
DOSAGE FORM/ STRENGTH: 6 mg, 12.5mg tablet
Naratriptan
Brand(s): Amerge
DOSAGE FORM/ STRENGTH: 1 mg, 2.5 mg tablet
Rizatriptan
Brand(s): Maxalt, Maxalt RPD
DOSAGE FORM/ STRENGTH: 5 mg, 10 mg tablet and wafer
Sumatriptan
Brand(s): Imitrex
DOSAGE FORM/ STRENGTH: 50 mg, 100 mg tablet
For the treatment of migraines with or without aura in patients who failed
adequate trials of other medications for migraines (e.g. acetaminophen, NSAIDs)
and where the following information is provided:
• Details of migraine prophylactic regimens (e.g. amitriptyline, beta-blockers) tried
or rationale why they are inappropriate; and
• The number of attacks, duration, and severity of migraines.
Duration of Approval: 5 years
Renewal requests may be considered for patients who continue to benefit from
treatment. The physician must provide the frequency of triptan use.
Warning: The frequent use of triptans (i.e. more than three days per week for longer
than three months at a time) may predispose a patient to developing triptan-induced
chronic daily headaches.
217
EAP source: eap-frequently-requested-drugs-2025-01-01.txt, page 217, record 124, corpus 2025-01-01; name match only, not an eligibility decision
1 brand, same coverage
Sandoz Almotriptan · DIN 02405334
Manufacturer: Sandoz Canada Inc.; listing date 2013-09-27
Health Canada: Marketed since 2013-07-22 · brand SANDOZ ALMOTRIPTAN · ATC N02CC05 ALMOTRIPTAN · form Tablet · route Oral · ingredients ALMOTRIPTAN (ALMOTRIPTAN MALATE) 12.5 MG · company Sandoz canada incorporated · schedule Prescription
Check this DIN again · Health Canada product recordSandoz Almotriptan: Formulary list price $9.7825/unit (unit not stated in source; not the patient's cost)
Ministry pays: $9.7825 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=89013 · Verify on the e-Formulary ↗ (DIN 02405334)
Source record
The source extract's flag for this DIN is unclear — confirm on the e-Formulary before prescribing (DIN 02405334).
DIN 02405334: Sandoz Almotriptan
Raw flags: sec3=Y, sec3b=Y, sec3bEAP=Y
Item: 289200016; group id 534; item number 1444; lccId None; manufacturer id SDZ
Source form: Tab; strength: 12.5mg
Recorded listing: Off-Formulary Interchangeable, not an ODB benefit; may be reimbursed through the Exceptional Access Program when approved (likely, unconfirmed)
Source prices (unrounded): $9.7825; ministry $9.7825
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02405334
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=89013
Interchangeable products
Almotriptan · DIN 02466821 · $9.7833
Apo-Almotriptan · DIN 02405806 · $9.7833
Axert · DIN 02248129 · not recorded
Mylan-Almotriptan · DIN 02398443 · $9.7833
Teva-Almotriptan · DIN 02434849 · $9.7833
Shortage status: resolved shortage (ended 2026-05-04); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02405334
Shortage record checked 2026-09-13T08:10:21.292534+00:00
Teva-Almotriptan · DIN 02434849 · 12.5mg · tablet
Off-Formulary Interchangeable, not an ODB benefitMarketed · checked 2026-09-02
StatusOff-Formulary Interchangeable, not an ODB benefit
Write on scriptnot a benefit; no Exceptional Access criteria on record; see alternatives
Patient paysPatient pays: program not supplied; amount cannot be determined.
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Ministry criteria list dated January 1, 2025; the program's current criteria may differ; SADIE shows the current version. Current criteria in SADIE
Coverage criteria
Exceptional Access criteria on record are for Brand(s): Axert; DOSAGE FORM/ STRENGTH: 6 mg, 12.5mg tablet — not this product; no criteria on record for this product in this block.
Exceptional Access Program criteria on record (ministry list dated 2025-01-01, not exhaustive):
Ministry criteria list dated January 1, 2025; the program's current criteria may differ; SADIE shows the current version. https://www.ontario.ca/page/sadie-special-authorization-digital-information-exchange
Almotriptan
Brand(s): Axert
DOSAGE FORM/ STRENGTH: 6 mg, 12.5mg tablet
Naratriptan
Brand(s): Amerge
DOSAGE FORM/ STRENGTH: 1 mg, 2.5 mg tablet
Rizatriptan
Brand(s): Maxalt, Maxalt RPD
DOSAGE FORM/ STRENGTH: 5 mg, 10 mg tablet and wafer
Sumatriptan
Brand(s): Imitrex
DOSAGE FORM/ STRENGTH: 50 mg, 100 mg tablet
For the treatment of migraines with or without aura in patients who failed
adequate trials of other medications for migraines (e.g. acetaminophen, NSAIDs)
and where the following information is provided:
• Details of migraine prophylactic regimens (e.g. amitriptyline, beta-blockers) tried
or rationale why they are inappropriate; and
• The number of attacks, duration, and severity of migraines.
Duration of Approval: 5 years
Renewal requests may be considered for patients who continue to benefit from
treatment. The physician must provide the frequency of triptan use.
Warning: The frequent use of triptans (i.e. more than three days per week for longer
than three months at a time) may predispose a patient to developing triptan-induced
chronic daily headaches.
217
EAP source: eap-frequently-requested-drugs-2025-01-01.txt, page 217, record 124, corpus 2025-01-01; name match only, not an eligibility decision
Brand vs generic price
Lowest DBP recovery rule under medically necessary no-substitution claims:
6.2 Medically Necessary "No Substitution" Claims
The Side Effect Reporting Form will not have to be renewed. However, the
pharmacy must maintain a copy of the prescription that contains a direction that
there be no substitution and the required Health Canada Side Effect Reporting Form
(completed and signed by the prescriber). The prescriber must write “No
Substitution” or “No Sub” on renewal or subsequent new written prescriptions, and
indicate “No Substitution” on subsequent new oral prescriptions. The dispenser will
be reimbursed the DBP plus a mark-up and the lesser of the posted usual and
customary fee or the ODB dispensing fee minus the applicable ODB co-payment
amount. Where a completed Side Effect Reporting Form is not available at the
pharmacy during an inspection, the difference between the cost of the higher-cost
product and the lowest DBP listed for the interchangeable category will be
recovered.
(ontario.ca, Revision #17; 2026-08-03 ↗)
6.2 Medically Necessary "No Substitution" Claims
The Ministry will provide reimbursement of a higher-cost interchangeable product in
medically necessary circumstances where a patient has experienced a significant
adverse reaction with two (2) lower-cost interchangeable drug products, where
available. When a prescriber identifies a patient for which it is medically necessary
that a higher cost interchangeable product be provided, the prescriber must:
• Complete, sign and forward to the pharmacist a copy of the Health Canada
side effect reporting form for each lower-cost interchangeable drug product
trialed (Side Effect Reporting Form[s]); and
• Write “No Substitution” or “No Sub” on a written prescription or indicate “No
Substitution” to the pharmacist in the case of a verbal prescription.
The prescriber should keep a copy of the completed form in the patient’s record for
future use and reference.
In the case of a written prescription, when the pharmacist or dispensing physician
receives a prescription with the written notation “No Substitution” or “No Sub”,
reimbursement will be provided for the higher-cost interchangeable product only if
the prescription is accompanied by a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed.
This form must be completely filled out noting the details of the adverse reaction
and signed by the prescriber.
In the case of a verbal prescription, the prescriber must satisfy the operator of the
pharmacy or dispensing physician that a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed
has been completed and signed by the prescriber. A written record of this verbal
prescription and the completed Health Canada Side Effect Reporting Form must be
received by the pharmacy prior to claim submission.
Upon receipt, the pharmacist must:
• Fax, submit online or mail the completed and signed form to Health Canada’s
Canada Vigilance Program; and
• Retain his or her copy of the completed and signed Side Effect Reporting
Form.
(ontario.ca, Revision #17; 2026-08-03 ↗)1 brand, same coverage
Teva-Almotriptan · DIN 02434849
Manufacturer: Teva Canada Limited; listing date 2015-06-29
Health Canada: Marketed since 2014-12-12 · brand TEVA-ALMOTRIPTAN · ATC N02CC05 ALMOTRIPTAN · form Tablet · route Oral · ingredients ALMOTRIPTAN (ALMOTRIPTAN MALATE) 12.5 MG · company Teva canada limited · schedule Prescription
Check this DIN again · Health Canada product recordTeva-Almotriptan: Formulary list price $9.7833/unit (unit not stated in source; not the patient's cost)
Ministry pays: $9.7833 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=91914 · Verify on the e-Formulary ↗ (DIN 02434849)
Source record
The source extract's flag for this DIN is unclear — confirm on the e-Formulary before prescribing (DIN 02434849).
DIN 02434849: Teva-Almotriptan
Raw flags: sec3=Y, sec3b=Y, sec3bEAP=Y
Item: 289200016; group id 534; item number 1444; lccId None; manufacturer id TEV
Source form: Tab; strength: 12.5mg
Recorded listing: Off-Formulary Interchangeable, not an ODB benefit; may be reimbursed through the Exceptional Access Program when approved (likely, unconfirmed)
Source prices (unrounded): $9.7833; ministry $9.7833
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02434849
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=91914
Interchangeable products
Almotriptan · DIN 02466821 · $9.7833
Apo-Almotriptan · DIN 02405806 · $9.7833
Axert · DIN 02248129 · not recorded
Mylan-Almotriptan · DIN 02398443 · $9.7833
Sandoz Almotriptan · DIN 02405334 · $9.7825
Shortage status: discontinued (2025-06-16, reported by TEVA CANADA LIMITED); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02434849
Shortage record checked 2026-09-13T08:10:21.292534+00:00
Apo-Almotriptan · DIN 02405792 · 6.25mg · tablet
StatusOff-Formulary Interchangeable, not an ODB benefit
Write on scriptnot a benefit; no Exceptional Access criteria on record; see alternatives
Patient paysPatient pays: program not supplied; amount cannot be determined.
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Ministry criteria list dated January 1, 2025; the program's current criteria may differ; SADIE shows the current version. Current criteria in SADIE
Coverage criteria
Exceptional Access criteria on record are for Brand(s): Axert; DOSAGE FORM/ STRENGTH: 6 mg, 12.5mg tablet — not this product; no criteria on record for this product in this block.
Exceptional Access Program criteria on record (ministry list dated 2025-01-01, not exhaustive):
Ministry criteria list dated January 1, 2025; the program's current criteria may differ; SADIE shows the current version. https://www.ontario.ca/page/sadie-special-authorization-digital-information-exchange
Almotriptan
Brand(s): Axert
DOSAGE FORM/ STRENGTH: 6 mg, 12.5mg tablet
Naratriptan
Brand(s): Amerge
DOSAGE FORM/ STRENGTH: 1 mg, 2.5 mg tablet
Rizatriptan
Brand(s): Maxalt, Maxalt RPD
DOSAGE FORM/ STRENGTH: 5 mg, 10 mg tablet and wafer
Sumatriptan
Brand(s): Imitrex
DOSAGE FORM/ STRENGTH: 50 mg, 100 mg tablet
For the treatment of migraines with or without aura in patients who failed
adequate trials of other medications for migraines (e.g. acetaminophen, NSAIDs)
and where the following information is provided:
• Details of migraine prophylactic regimens (e.g. amitriptyline, beta-blockers) tried
or rationale why they are inappropriate; and
• The number of attacks, duration, and severity of migraines.
Duration of Approval: 5 years
Renewal requests may be considered for patients who continue to benefit from
treatment. The physician must provide the frequency of triptan use.
Warning: The frequent use of triptans (i.e. more than three days per week for longer
than three months at a time) may predispose a patient to developing triptan-induced
chronic daily headaches.
217
EAP source: eap-frequently-requested-drugs-2025-01-01.txt, page 217, record 124, corpus 2025-01-01; name match only, not an eligibility decision
1 brand, same coverage
Apo-Almotriptan · DIN 02405792
Manufacturer: Apotex Inc.; listing date 2013-09-27
Health Canada: Dormant since 2017-08-04 · brand APO-ALMOTRIPTAN · ATC N02CC05 ALMOTRIPTAN · form Tablet · route Oral · ingredients ALMOTRIPTAN (ALMOTRIPTAN MALATE) 6.25 MG · company Apotex inc · schedule Prescription
Check this DIN again · Health Canada product recordApo-Almotriptan: Formulary list price $9.7833/unit (unit not stated in source; not the patient's cost)
Ministry pays: $9.7833 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=89056 · Verify on the e-Formulary ↗ (DIN 02405792)
Source record
The source extract's flag for this DIN is unclear — confirm on the e-Formulary before prescribing (DIN 02405792).
DIN 02405792: Apo-Almotriptan
Raw flags: sec3=Y, sec3b=Y, sec3bEAP=Y
Item: 289200017; group id 534; item number 1443; lccId None; manufacturer id APX
Source form: Tab; strength: 6.25mg
Recorded listing: Off-Formulary Interchangeable, not an ODB benefit; may be reimbursed through the Exceptional Access Program when approved (likely, unconfirmed)
Source prices (unrounded): $9.7833; ministry $9.7833
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02405792
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=89056
Interchangeable products
Axert · DIN 02248128 · not recorded
Mylan-Almotriptan · DIN 02398435 · $9.7833
Shortage status: resolved shortage (ended 2019-05-13); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02405792
Shortage record checked 2026-09-13T08:10:21.292534+00:00
Health Canada lists this DIN as Dormant since 2017-08-04 — choose a marketed DIN from the same-category list.
Apo-Almotriptan · DIN 02405806 · 12.5mg · tablet
Off-Formulary Interchangeable, not an ODB benefitDormant since 2017-08-04 · checked 2026-09-02
StatusOff-Formulary Interchangeable, not an ODB benefit
Write on scriptnot a benefit; no Exceptional Access criteria on record; see alternatives
Patient paysPatient pays: program not supplied; amount cannot be determined.
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Ministry criteria list dated January 1, 2025; the program's current criteria may differ; SADIE shows the current version. Current criteria in SADIE
Coverage criteria
Exceptional Access criteria on record are for Brand(s): Axert; DOSAGE FORM/ STRENGTH: 6 mg, 12.5mg tablet — not this product; no criteria on record for this product in this block.
Exceptional Access Program criteria on record (ministry list dated 2025-01-01, not exhaustive):
Ministry criteria list dated January 1, 2025; the program's current criteria may differ; SADIE shows the current version. https://www.ontario.ca/page/sadie-special-authorization-digital-information-exchange
Almotriptan
Brand(s): Axert
DOSAGE FORM/ STRENGTH: 6 mg, 12.5mg tablet
Naratriptan
Brand(s): Amerge
DOSAGE FORM/ STRENGTH: 1 mg, 2.5 mg tablet
Rizatriptan
Brand(s): Maxalt, Maxalt RPD
DOSAGE FORM/ STRENGTH: 5 mg, 10 mg tablet and wafer
Sumatriptan
Brand(s): Imitrex
DOSAGE FORM/ STRENGTH: 50 mg, 100 mg tablet
For the treatment of migraines with or without aura in patients who failed
adequate trials of other medications for migraines (e.g. acetaminophen, NSAIDs)
and where the following information is provided:
• Details of migraine prophylactic regimens (e.g. amitriptyline, beta-blockers) tried
or rationale why they are inappropriate; and
• The number of attacks, duration, and severity of migraines.
Duration of Approval: 5 years
Renewal requests may be considered for patients who continue to benefit from
treatment. The physician must provide the frequency of triptan use.
Warning: The frequent use of triptans (i.e. more than three days per week for longer
than three months at a time) may predispose a patient to developing triptan-induced
chronic daily headaches.
217
EAP source: eap-frequently-requested-drugs-2025-01-01.txt, page 217, record 124, corpus 2025-01-01; name match only, not an eligibility decision
Brand vs generic price
Lowest DBP recovery rule under medically necessary no-substitution claims:
6.2 Medically Necessary "No Substitution" Claims
The Side Effect Reporting Form will not have to be renewed. However, the
pharmacy must maintain a copy of the prescription that contains a direction that
there be no substitution and the required Health Canada Side Effect Reporting Form
(completed and signed by the prescriber). The prescriber must write “No
Substitution” or “No Sub” on renewal or subsequent new written prescriptions, and
indicate “No Substitution” on subsequent new oral prescriptions. The dispenser will
be reimbursed the DBP plus a mark-up and the lesser of the posted usual and
customary fee or the ODB dispensing fee minus the applicable ODB co-payment
amount. Where a completed Side Effect Reporting Form is not available at the
pharmacy during an inspection, the difference between the cost of the higher-cost
product and the lowest DBP listed for the interchangeable category will be
recovered.
(ontario.ca, Revision #17; 2026-08-03 ↗)
6.2 Medically Necessary "No Substitution" Claims
The Ministry will provide reimbursement of a higher-cost interchangeable product in
medically necessary circumstances where a patient has experienced a significant
adverse reaction with two (2) lower-cost interchangeable drug products, where
available. When a prescriber identifies a patient for which it is medically necessary
that a higher cost interchangeable product be provided, the prescriber must:
• Complete, sign and forward to the pharmacist a copy of the Health Canada
side effect reporting form for each lower-cost interchangeable drug product
trialed (Side Effect Reporting Form[s]); and
• Write “No Substitution” or “No Sub” on a written prescription or indicate “No
Substitution” to the pharmacist in the case of a verbal prescription.
The prescriber should keep a copy of the completed form in the patient’s record for
future use and reference.
In the case of a written prescription, when the pharmacist or dispensing physician
receives a prescription with the written notation “No Substitution” or “No Sub”,
reimbursement will be provided for the higher-cost interchangeable product only if
the prescription is accompanied by a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed.
This form must be completely filled out noting the details of the adverse reaction
and signed by the prescriber.
In the case of a verbal prescription, the prescriber must satisfy the operator of the
pharmacy or dispensing physician that a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed
has been completed and signed by the prescriber. A written record of this verbal
prescription and the completed Health Canada Side Effect Reporting Form must be
received by the pharmacy prior to claim submission.
Upon receipt, the pharmacist must:
• Fax, submit online or mail the completed and signed form to Health Canada’s
Canada Vigilance Program; and
• Retain his or her copy of the completed and signed Side Effect Reporting
Form.
(ontario.ca, Revision #17; 2026-08-03 ↗)1 brand, same coverage
Apo-Almotriptan · DIN 02405806
Manufacturer: Apotex Inc.; listing date 2013-09-27
Health Canada: Dormant since 2017-08-04 · brand APO-ALMOTRIPTAN · ATC N02CC05 ALMOTRIPTAN · form Tablet · route Oral · ingredients ALMOTRIPTAN (ALMOTRIPTAN MALATE) 12.5 MG · company Apotex inc · schedule Prescription
Check this DIN again · Health Canada product recordApo-Almotriptan: Formulary list price $9.7833/unit (unit not stated in source; not the patient's cost)
Ministry pays: $9.7833 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=89057 · Verify on the e-Formulary ↗ (DIN 02405806)
Source record
The source extract's flag for this DIN is unclear — confirm on the e-Formulary before prescribing (DIN 02405806).
DIN 02405806: Apo-Almotriptan
Raw flags: sec3=Y, sec3b=Y, sec3bEAP=Y
Item: 289200016; group id 534; item number 1444; lccId None; manufacturer id APX
Source form: Tab; strength: 12.5mg
Recorded listing: Off-Formulary Interchangeable, not an ODB benefit; may be reimbursed through the Exceptional Access Program when approved (likely, unconfirmed)
Source prices (unrounded): $9.7833; ministry $9.7833
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02405806
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=89057
Interchangeable products
Almotriptan · DIN 02466821 · $9.7833
Axert · DIN 02248129 · not recorded
Mylan-Almotriptan · DIN 02398443 · $9.7833
Sandoz Almotriptan · DIN 02405334 · $9.7825
Teva-Almotriptan · DIN 02434849 · $9.7833
Shortage status: resolved shortage (ended 2019-05-13); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02405806
Shortage record checked 2026-09-13T08:10:21.292534+00:00
Health Canada lists this DIN as Dormant since 2017-08-04 — choose a marketed DIN from the same-category list.
Axert · DIN 02248128 · 6.25mg · tablet
Off-Formulary Interchangeable, not an ODB benefit; Health Canada lists this DIN as Cancelled post market since 2017-10-27 — choose a marketed DIN from the same-category list.Discontinued 2017-10-27 · checked 2026-09-02
StatusOff-Formulary Interchangeable, not an ODB benefit; Health Canada lists this DIN as Cancelled post market since 2017-10-27 — choose a marketed DIN from the same-category list.
Write on scriptnot a benefit; no Exceptional Access criteria on record; see alternatives; Health Canada lists this DIN as Cancelled post market since 2017-10-27 — choose a marketed DIN from the same-category list.
Patient paysPatient pays: program not supplied; amount cannot be determined.
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Ministry criteria list dated January 1, 2025; the program's current criteria may differ; SADIE shows the current version. Current criteria in SADIE
Coverage criteria
Exceptional Access criteria on record are for Brand(s): Axert; DOSAGE FORM/ STRENGTH: 6 mg, 12.5mg tablet — not this product; no criteria on record for this product in this block.
Exceptional Access Program criteria on record (ministry list dated 2025-01-01, not exhaustive):
Ministry criteria list dated January 1, 2025; the program's current criteria may differ; SADIE shows the current version. https://www.ontario.ca/page/sadie-special-authorization-digital-information-exchange
Almotriptan
Brand(s): Axert
DOSAGE FORM/ STRENGTH: 6 mg, 12.5mg tablet
Naratriptan
Brand(s): Amerge
DOSAGE FORM/ STRENGTH: 1 mg, 2.5 mg tablet
Rizatriptan
Brand(s): Maxalt, Maxalt RPD
DOSAGE FORM/ STRENGTH: 5 mg, 10 mg tablet and wafer
Sumatriptan
Brand(s): Imitrex
DOSAGE FORM/ STRENGTH: 50 mg, 100 mg tablet
For the treatment of migraines with or without aura in patients who failed
adequate trials of other medications for migraines (e.g. acetaminophen, NSAIDs)
and where the following information is provided:
• Details of migraine prophylactic regimens (e.g. amitriptyline, beta-blockers) tried
or rationale why they are inappropriate; and
• The number of attacks, duration, and severity of migraines.
Duration of Approval: 5 years
Renewal requests may be considered for patients who continue to benefit from
treatment. The physician must provide the frequency of triptan use.
Warning: The frequent use of triptans (i.e. more than three days per week for longer
than three months at a time) may predispose a patient to developing triptan-induced
chronic daily headaches.
217
EAP source: eap-frequently-requested-drugs-2025-01-01.txt, page 217, record 124, corpus 2025-01-01; name match only, not an eligibility decision
1 brand, same coverage
Axert · DIN 02248128
Manufacturer: Janssen-Ortho Inc.; listing date 2013-09-27
Health Canada: Cancelled post market since 2017-10-27 · brand AXERT 6.25MG · ATC N02CC05 ALMOTRIPTAN · form Tablet · route Oral · ingredients ALMOTRIPTAN (ALMOTRIPTAN MALATE) 6.25 MG · company Mcneil consumer healthcare division of johnson & johnson inc · schedule Prescription
Check this DIN again · Health Canada product recordAxert: Formulary list price not recorded/unit (unit not stated in source; not the patient's cost)
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=72455 · Verify on the e-Formulary ↗ (DIN 02248128)
Source record
The source extract's flag for this DIN is unclear — confirm on the e-Formulary before prescribing (DIN 02248128).
DIN 02248128: Axert
Raw flags: sec3=Y, sec3b=Y, sec3bEAP=Y
Item: 289200017; group id 534; item number 1443; lccId None; manufacturer id JNO
Source form: Tab; strength: 6.25mg
Recorded listing: Off-Formulary Interchangeable, not an ODB benefit; may be reimbursed through the Exceptional Access Program when approved (likely, unconfirmed)
Source prices (unrounded): not recorded; ministry not recorded
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02248128
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=72455
Interchangeable products
Apo-Almotriptan · DIN 02405792 · $9.7833
Mylan-Almotriptan · DIN 02398435 · $9.7833
Shortage status: discontinued (2017-10-27, reported by MCNEIL CONSUMER HEALTHCARE DIVISION OF JOHNSON & JOHNSON INC); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02248128
Shortage record checked 2026-09-13T08:10:21.292534+00:00
Health Canada lists this DIN as Cancelled post market since 2017-10-27 — choose a marketed DIN from the same-category list.
Axert · DIN 02248129 · 12.5mg · tablet
Off-Formulary Interchangeable, not an ODB benefit; Health Canada lists this DIN as Cancelled post market since 2017-10-27 — choose a marketed DIN from the same-category list.Discontinued 2017-10-27 · checked 2026-09-02
StatusOff-Formulary Interchangeable, not an ODB benefit; Health Canada lists this DIN as Cancelled post market since 2017-10-27 — choose a marketed DIN from the same-category list.
Write on scriptExceptional Access application required. For a drug to be considered for funding, the EAP reimbursement criteria must always be met and the request approved prior to the initiation of treatment with the drug being requested, unless otherwise specified within the criteria. (ontario.ca, Aug 31, 2026 ↗) Submit through SADIE: "The SADIE portal is available to authorized prescribers and their delegates and designates, enabling the creation, submission and tracking of web-based electronic requests directly to the Exceptional Access Program." (ontario.ca, Aug 31, 2026 ↗); Health Canada lists this DIN as Cancelled post market since 2017-10-27 — choose a marketed DIN from the same-category list. Patient paysPatient pays: program not supplied; amount cannot be determined.
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Ministry criteria list dated January 1, 2025; the program's current criteria may differ; SADIE shows the current version. Current criteria in SADIE
Coverage criteria
Exceptional Access Program criteria on record (ministry list dated 2025-01-01, not exhaustive):
Ministry criteria list dated January 1, 2025; the program's current criteria may differ; SADIE shows the current version. https://www.ontario.ca/page/sadie-special-authorization-digital-information-exchange
Almotriptan
Brand(s): Axert
DOSAGE FORM/ STRENGTH: 6 mg, 12.5mg tablet
Naratriptan
Brand(s): Amerge
DOSAGE FORM/ STRENGTH: 1 mg, 2.5 mg tablet
Rizatriptan
Brand(s): Maxalt, Maxalt RPD
DOSAGE FORM/ STRENGTH: 5 mg, 10 mg tablet and wafer
Sumatriptan
Brand(s): Imitrex
DOSAGE FORM/ STRENGTH: 50 mg, 100 mg tablet
For the treatment of migraines with or without aura in patients who failed
adequate trials of other medications for migraines (e.g. acetaminophen, NSAIDs)
and where the following information is provided:
• Details of migraine prophylactic regimens (e.g. amitriptyline, beta-blockers) tried
or rationale why they are inappropriate; and
• The number of attacks, duration, and severity of migraines.
Duration of Approval: 5 years
Renewal requests may be considered for patients who continue to benefit from
treatment. The physician must provide the frequency of triptan use.
Warning: The frequent use of triptans (i.e. more than three days per week for longer
than three months at a time) may predispose a patient to developing triptan-induced
chronic daily headaches.
217
EAP source: eap-frequently-requested-drugs-2025-01-01.txt, page 217, record 124, corpus 2025-01-01; name match only, not an eligibility decision
Brand vs generic price
Lowest DBP recovery rule under medically necessary no-substitution claims:
6.2 Medically Necessary "No Substitution" Claims
The Side Effect Reporting Form will not have to be renewed. However, the
pharmacy must maintain a copy of the prescription that contains a direction that
there be no substitution and the required Health Canada Side Effect Reporting Form
(completed and signed by the prescriber). The prescriber must write “No
Substitution” or “No Sub” on renewal or subsequent new written prescriptions, and
indicate “No Substitution” on subsequent new oral prescriptions. The dispenser will
be reimbursed the DBP plus a mark-up and the lesser of the posted usual and
customary fee or the ODB dispensing fee minus the applicable ODB co-payment
amount. Where a completed Side Effect Reporting Form is not available at the
pharmacy during an inspection, the difference between the cost of the higher-cost
product and the lowest DBP listed for the interchangeable category will be
recovered.
(ontario.ca, Revision #17; 2026-08-03 ↗)
6.2 Medically Necessary "No Substitution" Claims
The Ministry will provide reimbursement of a higher-cost interchangeable product in
medically necessary circumstances where a patient has experienced a significant
adverse reaction with two (2) lower-cost interchangeable drug products, where
available. When a prescriber identifies a patient for which it is medically necessary
that a higher cost interchangeable product be provided, the prescriber must:
• Complete, sign and forward to the pharmacist a copy of the Health Canada
side effect reporting form for each lower-cost interchangeable drug product
trialed (Side Effect Reporting Form[s]); and
• Write “No Substitution” or “No Sub” on a written prescription or indicate “No
Substitution” to the pharmacist in the case of a verbal prescription.
The prescriber should keep a copy of the completed form in the patient’s record for
future use and reference.
In the case of a written prescription, when the pharmacist or dispensing physician
receives a prescription with the written notation “No Substitution” or “No Sub”,
reimbursement will be provided for the higher-cost interchangeable product only if
the prescription is accompanied by a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed.
This form must be completely filled out noting the details of the adverse reaction
and signed by the prescriber.
In the case of a verbal prescription, the prescriber must satisfy the operator of the
pharmacy or dispensing physician that a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed
has been completed and signed by the prescriber. A written record of this verbal
prescription and the completed Health Canada Side Effect Reporting Form must be
received by the pharmacy prior to claim submission.
Upon receipt, the pharmacist must:
• Fax, submit online or mail the completed and signed form to Health Canada’s
Canada Vigilance Program; and
• Retain his or her copy of the completed and signed Side Effect Reporting
Form.
(ontario.ca, Revision #17; 2026-08-03 ↗)How long EAP takes
Turnaround times
The Exceptional Access Program receives between 250 and 500 requests a day. Requests are categorized in order of priority based on how quickly a drug is needed, the type of drug, and the condition for which the drug is being used.
Turnaround times begin on the business day on which the EAP receives a complete request from a physician or nurse practitioner. You may have to wait longer if the request is missing information or supporting documents required by the EAP criteria, if a request requires external review, or if documents are sent by fax or mail instead of submitted via SADIE.
EAP Weekly Progress Report
Date: September 15, 2026
Processing categories and examples | Target | Current |
Priority 1 — for drugs such as antibiotics, cancer medications, and initial requests for pain medications | 3 business days | 2 business day |
Priority 2 — for antiviral drugs to treat HIV, drugs for multiple sclerosis, and pulmonary hypertension | 5 business days | 3 business days |
Biologics — for biologic drugs to treat rheumatoid arthritis, psoriatic arthritis, ulcerative colitis and Crohn’s disease | 10 business days | 4 business days |
Chronic — for drugs used for chronic conditions such as migraines, chronic pain, Ménière's disease and symptoms of Parkinson’s disease. | 4 to 6 weeks | 11 business days |
(ontario.ca, Updated September 15, 2026 ↗)
For selected drugs, the Telephone Request Service is available to authorized prescribers or their delegates. In most cases, the funding decision is provided by the end of the call and processed within one business day.
(ontario.ca, Updated September 15, 2026 ↗)1 brand, same coverage
Axert · DIN 02248129
Manufacturer: Janssen-Ortho Inc.; listing date 2013-09-27
Health Canada: Cancelled post market since 2017-10-27 · brand AXERT 12.5MG · ATC N02CC05 ALMOTRIPTAN · form Tablet · route Oral · ingredients ALMOTRIPTAN (ALMOTRIPTAN MALATE) 12.5 MG · company Mcneil consumer healthcare division of johnson & johnson inc · schedule Prescription
Check this DIN again · Health Canada product recordAxert: Formulary list price not recorded/unit (unit not stated in source; not the patient's cost)
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=72456 · Verify on the e-Formulary ↗ (DIN 02248129)
Source record
The source extract's flag for this DIN is unclear — confirm on the e-Formulary before prescribing (DIN 02248129).
DIN 02248129: Axert
Raw flags: sec3=Y, sec3b=Y, sec3bEAP=Y
Item: 289200016; group id 534; item number 1444; lccId None; manufacturer id JNO
Source form: Tab; strength: 12.5mg
Recorded listing: Off-Formulary Interchangeable, not an ODB benefit; may be reimbursed through the Exceptional Access Program when approved (likely, unconfirmed)
Source prices (unrounded): not recorded; ministry not recorded
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02248129
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=72456
Interchangeable products
Almotriptan · DIN 02466821 · $9.7833
Apo-Almotriptan · DIN 02405806 · $9.7833
Mylan-Almotriptan · DIN 02398443 · $9.7833
Sandoz Almotriptan · DIN 02405334 · $9.7825
Teva-Almotriptan · DIN 02434849 · $9.7833
Shortage status: discontinued (2017-10-27, reported by MCNEIL CONSUMER HEALTHCARE DIVISION OF JOHNSON & JOHNSON INC); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02248129
Shortage record checked 2026-09-13T08:10:21.292534+00:00
Health Canada lists this DIN as Cancelled post market since 2017-10-27 — choose a marketed DIN from the same-category list.
Other drugs in the same formulary class (28:92 Miscellaneous Central Nervous System Drugs) and how they are covered
Matched class: 28:92 Miscellaneous Central Nervous System Drugs
Drug-class inventory only. Lists recorded Ontario formulary products, not every Canadian medication; does not recommend treatment.
Covered without a code on the Ontario formulary: PIZOTYLINE
Some products covered without a code (check the product listing): ATOMOXETINE HCL, PRAMIPEXOLE DIHYDROCHLORIDE MONOHYDRATE
28:92 Miscellaneous Central Nervous System Drugs
· 16 products · Off-Formulary Interchangeable, not an ODB benefit · strengths: 20mg, 40mg · Tab
· 6 products · Off-Formulary Interchangeable, not an ODB benefit · strengths: 2.5mg · Tab
· 6 products · Off-Formulary Interchangeable, not an ODB benefit · strengths: 1mg, 2.5mg · Tab
· 44 products · Off-Formulary Interchangeable, not an ODB benefit · strengths: 5mg, 10mg · Orally Disintegrating Tab, Tab
· 37 products · Off-Formulary Interchangeable, not an ODB benefit · strengths: 6mg/0.5mL, 25mg, 50mg, 100mg · Inj Sol-Pref Syr 0.5mL Pk, Tab
· 21 products · Off-Formulary Interchangeable, not an ODB benefit · strengths: 2.5mg · Orally Disintegrating Tab, Tab
· 1 products · General benefit · strengths: 1mg · Tab
· 59 products · Listed, not a benefit (5), General benefit (40), Off-Formulary Interchangeable, not an ODB benefit (14) · strengths: 10mg, 18mg, 25mg, 40mg, 60mg, 80mg, 100mg · Cap
· 28 products · General benefit (19), Off-Formulary Interchangeable, not an ODB benefit (7), Listed, not a benefit (2) · strengths: 0.25mg, 0.5mg, 1mg, 1.5mg · Tab
· 1 products ·
Limited Use, codes 531 · strengths: 333mg · DR Tab
· 4 products ·
Limited Use, codes 367 · strengths: 200mg · Tab
· 18 products · Off-Formulary Interchangeable, not an ODB benefit · strengths: 120mg, 240mg · DR Cap
Source: formulary-ed43-front-matter.txt Part V; ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26; class 28:92
and 1 more
Full class listing
Related classes: 28:08 Analgesics, 28:10 Opiate Antagonists, 28:12 Anticonvulsants, 28:16 Psychotherapeutic Agents, 28:20 C.N.S. Stimulants, 28:24 Sedatives and Hypnotics, 28:36 Antiparkinsonian Agents
Same formulary class, not same indication: class membership alone does not establish equivalent uses.
Other review policies
For Mylan-Almotriptan, Almotriptan, Sandoz Almotriptan, Teva-Almotriptan, Apo-Almotriptan, Axert: no applicable EAP criteria are held and no ODB benefit is established. These policies do not establish coverage.
For rare, immediately life-, limb- or organ-threatening circumstances, the Compassionate Review Policy may consider an unfunded drug or indication, subject to its criteria and without bypassing the drug review process. Compassionate Review Policy
Compassionate Review Policy: source quote
Where there are rare clinical circumstances in immediately life, limb, or organ-threatening conditions, the Executive Officer will also consider requests for drugs or indications in situations where there has not been a decision by the Executive Officer to provide funding of the drug or indication as part of the Ontario Drug Benefit program (and the EAP), and the drug or indication requested would not circumvent the established review process for new drugs or indications as part of the drug submission process for listing within the Ontario Drug Benefit program. Requests must meet the criteria for the Compassionate Review Policy.
Ontario source; updated September 15, 2026
For cancer drugs, Case-by-Case Review considers rare, immediately life-threatening circumstances when no satisfactory funded treatment exists; its criteria and application process apply. Case-by-Case Review (cancer drugs)
Case-by-Case Review (cancer drugs): source quote
Note: Requests for cancer drugs are considered under the Case-by-Case Review Program (CBCRP) which is administered by Ontario Health (Cancer Care Ontario) on behalf of the Ministry of Health. The CBCRP considers funding requests for drugs (both oral therapies and injectable drugs) for the treatment of cancer in patients who have a rare clinical circumstance that is immediately life-threatening (death is likely within a matter of months) and who require treatment with an unfunded drug, because there is no other satisfactory and funded treatment. Please refer to the Ontario Health website for information on the application process, FAQs, eligibility criteria and program policies.
Ontario source; updated September 15, 2026