CELECOXIB
All strengths: Limited Use — Reason for Use code 316, 317 required; same patient cost rules
Shared coverage and patient cost rules
StatusLimited Use — Reason for Use code 316, 317 required
Patient paysPatient pays: program not supplied; amount cannot be determined.
Other products in the same Health Canada class (M01A) — coverage varies; not interchangeable
- Diclofenac (Voltaren): general benefit, Not a benefit
- Diclofenac + misoprostol (Arthrotec 50): general benefit
- Flurbiprofen (Ansaid): general benefit, Not a benefit
- Ibuprofen (Motrin): general benefit, Not a benefit
- Indomethacin (Indocid): general benefit, Not a benefit
- Ketoprofen (Ketoprofen): general benefit, Not a benefit
12 more in the class list below
AG-Celecoxib · DIN 02437570 · 100mg · capsule
Limited Use — Reason for Use code 316, 317 requiredMarketed · checked 2026-09-02
Write on scriptLU code 316, 317 (patient must meet the criteria below)
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Ontario Limited Use criteria — code 316, 317
Coverage limit:
Osteoarthritis
Reason for Use code 316
For patients who have failed an adequate trial of acetaminophen (e.g. acetaminophen 1g QID for several weeks) and have had:
Coverage limit:
History of a documented, clinically significant ulcer or GI bleed; or
Failure or intolerance to at least three listed NSAIDS.
Coverage limit:
The maximum daily dose of celecoxib which will be reimbursed for the treatment of osteoarthritis is 200mg.
Coverage limit:
LU Authorization Period: 1 year
Coverage limit:
Rheumatoid arthritis
Reason for Use code 317
For patients who have had:
Coverage limit:
History of a documented, clinically significant ulcer or GI bleed; or
Failure or intolerance to at least three listed NSAIDS.
Coverage limit:
The maximum daily dose of celecoxib which will be reimbursed for the treatment of rheumatoid arthritis is 400mg.
Coverage limit:
LU Authorization Period: 1 year
Brand vs generic price
Lowest DBP recovery rule under medically necessary no-substitution claims:
6.2 Medically Necessary "No Substitution" Claims
The Side Effect Reporting Form will not have to be renewed. However, the
pharmacy must maintain a copy of the prescription that contains a direction that
there be no substitution and the required Health Canada Side Effect Reporting Form
(completed and signed by the prescriber). The prescriber must write “No
Substitution” or “No Sub” on renewal or subsequent new written prescriptions, and
indicate “No Substitution” on subsequent new oral prescriptions. The dispenser will
be reimbursed the DBP plus a mark-up and the lesser of the posted usual and
customary fee or the ODB dispensing fee minus the applicable ODB co-payment
amount. Where a completed Side Effect Reporting Form is not available at the
pharmacy during an inspection, the difference between the cost of the higher-cost
product and the lowest DBP listed for the interchangeable category will be
recovered.
(ontario.ca, Revision #17; 2026-08-03 ↗)
6.2 Medically Necessary "No Substitution" Claims
The Ministry will provide reimbursement of a higher-cost interchangeable product in
medically necessary circumstances where a patient has experienced a significant
adverse reaction with two (2) lower-cost interchangeable drug products, where
available. When a prescriber identifies a patient for which it is medically necessary
that a higher cost interchangeable product be provided, the prescriber must:
• Complete, sign and forward to the pharmacist a copy of the Health Canada
side effect reporting form for each lower-cost interchangeable drug product
trialed (Side Effect Reporting Form[s]); and
• Write “No Substitution” or “No Sub” on a written prescription or indicate “No
Substitution” to the pharmacist in the case of a verbal prescription.
The prescriber should keep a copy of the completed form in the patient’s record for
future use and reference.
In the case of a written prescription, when the pharmacist or dispensing physician
receives a prescription with the written notation “No Substitution” or “No Sub”,
reimbursement will be provided for the higher-cost interchangeable product only if
the prescription is accompanied by a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed.
This form must be completely filled out noting the details of the adverse reaction
and signed by the prescriber.
In the case of a verbal prescription, the prescriber must satisfy the operator of the
pharmacy or dispensing physician that a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed
has been completed and signed by the prescriber. A written record of this verbal
prescription and the completed Health Canada Side Effect Reporting Form must be
received by the pharmacy prior to claim submission.
Upon receipt, the pharmacist must:
• Fax, submit online or mail the completed and signed form to Health Canada’s
Canada Vigilance Program; and
• Retain his or her copy of the completed and signed Side Effect Reporting
Form.
(ontario.ca, Revision #17; 2026-08-03 ↗)1 brand, same coverage
AG-Celecoxib · DIN 02437570
Manufacturer: Angita Pharma Inc.; listing date 2020-11-30
Health Canada: Marketed since 2019-05-13 · brand AG-CELECOXIB · ATC M01AH01 CELECOXIB · form Capsule · route Oral · ingredients CELECOXIB 100 MG · company Angita pharma inc. · schedule Prescription
Check this DIN again · Health Canada product recordAG-Celecoxib: Formulary list price $0.1279/unit (unit not stated in source; not the patient's cost)
Ministry pays: $0.1279 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=92190 · Verify on the e-Formulary ↗ (DIN 02437570)
Source record
DIN 02437570: AG-Celecoxib
Raw flags: sec12=Y, sec3=Y
Item: 280804075; group id 377; item number 0898; lccId 00064; manufacturer id ANG
Source form: Cap; strength: 100mg
Recorded listing: Limited Use: paid only with a Reason for Use code and the criteria below
Source prices (unrounded): $0.1279; ministry $0.1279
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02437570
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=92190
Therapeutic Notes (formulary)
NSAIDs have a high rate of serious adverse effects in the elderly. When prescribing NSAIDs, the minimal effective dose for the shortest period of time should be used. In nonspecific pain and/or osteoarthritis, in the absence of joint inflammation (swelling), acetaminophen is a better first choice for analgesia. The most effective treatment to prevent NSAID-gastritis is misoprostol; although H-2 antagonists, such as ranitidine or cimetidine, are commonly used, they are not as effective. NSAIDs can significantly aggravate hypertension and congestive heart failure; ASA in doses below 1 gram per day is a better choice than other NSAID options if anti-inflammatory effects are required in patients with these conditions. Low dose ASA has additional benefits for anti-platelet indications that are not provided by other NSAIDs, and should be given in preference or in addition to other NSAIDs for patients with vascular indications.
Interchangeable products
Act Celecoxib · DIN 02420155 · $0.1279
Apo-Celecoxib · DIN 02418932 · $0.1279
Auro-Celecoxib · DIN 02445670 · $0.1279
Bio-Celecoxib · DIN 02426382 · $0.1279
Celebrex · DIN 02239941 · $0.1279
Celecoxib · DIN 02429675 · $0.1279
Celecoxib · DIN 02436299 · $0.1279
Jamp-Celecoxib · DIN 02424533 · $0.1279
M-Celecoxib · DIN 02495465 · $0.1279
Mar-Celecoxib · DIN 02420058 · $0.1279
Mint-Celecoxib · DIN 02412497 · $0.1279
NRA-Celecoxib · DIN 02479737 · $0.1279
PMS-Celecoxib · DIN 02355442 · $0.1279
PMSC-Celecoxib · DIN 02517116 · $0.1279
Ran-Celecoxib · DIN 02412373 · $0.1279
Sdz Celecoxib · DIN 02442639 · $0.1279
Teva-Celecoxib · DIN 02288915 · $0.1279
Shortage status: no shortage or discontinuation reported (checked 2026-09-13T08:10:21.292534+00:00); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02437570
Shortage record checked 2026-09-13T08:10:21.292534+00:00
Apo-Celecoxib · DIN 02418932 · 100mg · capsule
Limited Use — Reason for Use code 316, 317 requiredMarketed · checked 2026-09-02
Write on scriptLU code 316, 317 (patient must meet the criteria below)
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Ontario Limited Use criteria — code 316, 317
Coverage limit:
Osteoarthritis
Reason for Use code 316
For patients who have failed an adequate trial of acetaminophen (e.g. acetaminophen 1g QID for several weeks) and have had:
Coverage limit:
History of a documented, clinically significant ulcer or GI bleed; or
Failure or intolerance to at least three listed NSAIDS.
Coverage limit:
The maximum daily dose of celecoxib which will be reimbursed for the treatment of osteoarthritis is 200mg.
Coverage limit:
LU Authorization Period: 1 year
Coverage limit:
Rheumatoid arthritis
Reason for Use code 317
For patients who have had:
Coverage limit:
History of a documented, clinically significant ulcer or GI bleed; or
Failure or intolerance to at least three listed NSAIDS.
Coverage limit:
The maximum daily dose of celecoxib which will be reimbursed for the treatment of rheumatoid arthritis is 400mg.
Coverage limit:
LU Authorization Period: 1 year
Brand vs generic price
Lowest DBP recovery rule under medically necessary no-substitution claims:
6.2 Medically Necessary "No Substitution" Claims
The Side Effect Reporting Form will not have to be renewed. However, the
pharmacy must maintain a copy of the prescription that contains a direction that
there be no substitution and the required Health Canada Side Effect Reporting Form
(completed and signed by the prescriber). The prescriber must write “No
Substitution” or “No Sub” on renewal or subsequent new written prescriptions, and
indicate “No Substitution” on subsequent new oral prescriptions. The dispenser will
be reimbursed the DBP plus a mark-up and the lesser of the posted usual and
customary fee or the ODB dispensing fee minus the applicable ODB co-payment
amount. Where a completed Side Effect Reporting Form is not available at the
pharmacy during an inspection, the difference between the cost of the higher-cost
product and the lowest DBP listed for the interchangeable category will be
recovered.
(ontario.ca, Revision #17; 2026-08-03 ↗)
6.2 Medically Necessary "No Substitution" Claims
The Ministry will provide reimbursement of a higher-cost interchangeable product in
medically necessary circumstances where a patient has experienced a significant
adverse reaction with two (2) lower-cost interchangeable drug products, where
available. When a prescriber identifies a patient for which it is medically necessary
that a higher cost interchangeable product be provided, the prescriber must:
• Complete, sign and forward to the pharmacist a copy of the Health Canada
side effect reporting form for each lower-cost interchangeable drug product
trialed (Side Effect Reporting Form[s]); and
• Write “No Substitution” or “No Sub” on a written prescription or indicate “No
Substitution” to the pharmacist in the case of a verbal prescription.
The prescriber should keep a copy of the completed form in the patient’s record for
future use and reference.
In the case of a written prescription, when the pharmacist or dispensing physician
receives a prescription with the written notation “No Substitution” or “No Sub”,
reimbursement will be provided for the higher-cost interchangeable product only if
the prescription is accompanied by a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed.
This form must be completely filled out noting the details of the adverse reaction
and signed by the prescriber.
In the case of a verbal prescription, the prescriber must satisfy the operator of the
pharmacy or dispensing physician that a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed
has been completed and signed by the prescriber. A written record of this verbal
prescription and the completed Health Canada Side Effect Reporting Form must be
received by the pharmacy prior to claim submission.
Upon receipt, the pharmacist must:
• Fax, submit online or mail the completed and signed form to Health Canada’s
Canada Vigilance Program; and
• Retain his or her copy of the completed and signed Side Effect Reporting
Form.
(ontario.ca, Revision #17; 2026-08-03 ↗)1 brand, same coverage
Apo-Celecoxib · DIN 02418932
Manufacturer: Apotex Inc.; listing date 2015-01-28
Health Canada: Marketed since 2014-11-17 · brand APO-CELECOXIB · ATC M01AH01 CELECOXIB · form Capsule · route Oral · ingredients CELECOXIB 100 MG · company Apotex inc · schedule Prescription
Check this DIN again · Health Canada product recordApo-Celecoxib: Formulary list price $0.1279/unit (unit not stated in source; not the patient's cost)
Ministry pays: $0.1279 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=90347 · Verify on the e-Formulary ↗ (DIN 02418932)
Source record
DIN 02418932: Apo-Celecoxib
Raw flags: sec12=Y, sec3=Y
Item: 280804075; group id 377; item number 0898; lccId 00064; manufacturer id APX
Source form: Cap; strength: 100mg
Recorded listing: Limited Use: paid only with a Reason for Use code and the criteria below
Source prices (unrounded): $0.1279; ministry $0.1279
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02418932
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=90347
Therapeutic Notes (formulary)
NSAIDs have a high rate of serious adverse effects in the elderly. When prescribing NSAIDs, the minimal effective dose for the shortest period of time should be used. In nonspecific pain and/or osteoarthritis, in the absence of joint inflammation (swelling), acetaminophen is a better first choice for analgesia. The most effective treatment to prevent NSAID-gastritis is misoprostol; although H-2 antagonists, such as ranitidine or cimetidine, are commonly used, they are not as effective. NSAIDs can significantly aggravate hypertension and congestive heart failure; ASA in doses below 1 gram per day is a better choice than other NSAID options if anti-inflammatory effects are required in patients with these conditions. Low dose ASA has additional benefits for anti-platelet indications that are not provided by other NSAIDs, and should be given in preference or in addition to other NSAIDs for patients with vascular indications.
Interchangeable products
AG-Celecoxib · DIN 02437570 · $0.1279
Act Celecoxib · DIN 02420155 · $0.1279
Auro-Celecoxib · DIN 02445670 · $0.1279
Bio-Celecoxib · DIN 02426382 · $0.1279
Celebrex · DIN 02239941 · $0.1279
Celecoxib · DIN 02429675 · $0.1279
Celecoxib · DIN 02436299 · $0.1279
Jamp-Celecoxib · DIN 02424533 · $0.1279
M-Celecoxib · DIN 02495465 · $0.1279
Mar-Celecoxib · DIN 02420058 · $0.1279
Mint-Celecoxib · DIN 02412497 · $0.1279
NRA-Celecoxib · DIN 02479737 · $0.1279
PMS-Celecoxib · DIN 02355442 · $0.1279
PMSC-Celecoxib · DIN 02517116 · $0.1279
Ran-Celecoxib · DIN 02412373 · $0.1279
Sdz Celecoxib · DIN 02442639 · $0.1279
Teva-Celecoxib · DIN 02288915 · $0.1279
Shortage status: resolved shortage (ended 2025-01-23); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02418932
Shortage record checked 2026-09-13T08:10:21.292534+00:00
Auro-Celecoxib · DIN 02445670 · 100mg · capsule
Limited Use — Reason for Use code 316, 317 requiredMarketed · checked 2026-09-02
Write on scriptLU code 316, 317 (patient must meet the criteria below)
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Ontario Limited Use criteria — code 316, 317
Coverage limit:
Osteoarthritis
Reason for Use code 316
For patients who have failed an adequate trial of acetaminophen (e.g. acetaminophen 1g QID for several weeks) and have had:
Coverage limit:
History of a documented, clinically significant ulcer or GI bleed; or
Failure or intolerance to at least three listed NSAIDS.
Coverage limit:
The maximum daily dose of celecoxib which will be reimbursed for the treatment of osteoarthritis is 200mg.
Coverage limit:
LU Authorization Period: 1 year
Coverage limit:
Rheumatoid arthritis
Reason for Use code 317
For patients who have had:
Coverage limit:
History of a documented, clinically significant ulcer or GI bleed; or
Failure or intolerance to at least three listed NSAIDS.
Coverage limit:
The maximum daily dose of celecoxib which will be reimbursed for the treatment of rheumatoid arthritis is 400mg.
Coverage limit:
LU Authorization Period: 1 year
Brand vs generic price
Lowest DBP recovery rule under medically necessary no-substitution claims:
6.2 Medically Necessary "No Substitution" Claims
The Side Effect Reporting Form will not have to be renewed. However, the
pharmacy must maintain a copy of the prescription that contains a direction that
there be no substitution and the required Health Canada Side Effect Reporting Form
(completed and signed by the prescriber). The prescriber must write “No
Substitution” or “No Sub” on renewal or subsequent new written prescriptions, and
indicate “No Substitution” on subsequent new oral prescriptions. The dispenser will
be reimbursed the DBP plus a mark-up and the lesser of the posted usual and
customary fee or the ODB dispensing fee minus the applicable ODB co-payment
amount. Where a completed Side Effect Reporting Form is not available at the
pharmacy during an inspection, the difference between the cost of the higher-cost
product and the lowest DBP listed for the interchangeable category will be
recovered.
(ontario.ca, Revision #17; 2026-08-03 ↗)
6.2 Medically Necessary "No Substitution" Claims
The Ministry will provide reimbursement of a higher-cost interchangeable product in
medically necessary circumstances where a patient has experienced a significant
adverse reaction with two (2) lower-cost interchangeable drug products, where
available. When a prescriber identifies a patient for which it is medically necessary
that a higher cost interchangeable product be provided, the prescriber must:
• Complete, sign and forward to the pharmacist a copy of the Health Canada
side effect reporting form for each lower-cost interchangeable drug product
trialed (Side Effect Reporting Form[s]); and
• Write “No Substitution” or “No Sub” on a written prescription or indicate “No
Substitution” to the pharmacist in the case of a verbal prescription.
The prescriber should keep a copy of the completed form in the patient’s record for
future use and reference.
In the case of a written prescription, when the pharmacist or dispensing physician
receives a prescription with the written notation “No Substitution” or “No Sub”,
reimbursement will be provided for the higher-cost interchangeable product only if
the prescription is accompanied by a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed.
This form must be completely filled out noting the details of the adverse reaction
and signed by the prescriber.
In the case of a verbal prescription, the prescriber must satisfy the operator of the
pharmacy or dispensing physician that a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed
has been completed and signed by the prescriber. A written record of this verbal
prescription and the completed Health Canada Side Effect Reporting Form must be
received by the pharmacy prior to claim submission.
Upon receipt, the pharmacist must:
• Fax, submit online or mail the completed and signed form to Health Canada’s
Canada Vigilance Program; and
• Retain his or her copy of the completed and signed Side Effect Reporting
Form.
(ontario.ca, Revision #17; 2026-08-03 ↗)1 brand, same coverage
Auro-Celecoxib · DIN 02445670
Manufacturer: Auro Pharma Inc.; listing date 2016-07-28
Health Canada: Marketed since 2015-12-02 · brand AURO-CELECOXIB · ATC M01AH01 CELECOXIB · form Capsule · route Oral · ingredients CELECOXIB 100 MG · company Auro pharma inc · schedule Prescription
Check this DIN again · Health Canada product recordAuro-Celecoxib: Formulary list price $0.1279/unit (unit not stated in source; not the patient's cost)
Ministry pays: $0.1279 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=93095 · Verify on the e-Formulary ↗ (DIN 02445670)
Source record
DIN 02445670: Auro-Celecoxib
Raw flags: sec12=Y, sec3=Y
Item: 280804075; group id 377; item number 0898; lccId 00064; manufacturer id AUR
Source form: Cap; strength: 100mg
Recorded listing: Limited Use: paid only with a Reason for Use code and the criteria below
Source prices (unrounded): $0.1279; ministry $0.1279
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02445670
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=93095
Therapeutic Notes (formulary)
NSAIDs have a high rate of serious adverse effects in the elderly. When prescribing NSAIDs, the minimal effective dose for the shortest period of time should be used. In nonspecific pain and/or osteoarthritis, in the absence of joint inflammation (swelling), acetaminophen is a better first choice for analgesia. The most effective treatment to prevent NSAID-gastritis is misoprostol; although H-2 antagonists, such as ranitidine or cimetidine, are commonly used, they are not as effective. NSAIDs can significantly aggravate hypertension and congestive heart failure; ASA in doses below 1 gram per day is a better choice than other NSAID options if anti-inflammatory effects are required in patients with these conditions. Low dose ASA has additional benefits for anti-platelet indications that are not provided by other NSAIDs, and should be given in preference or in addition to other NSAIDs for patients with vascular indications.
Interchangeable products
AG-Celecoxib · DIN 02437570 · $0.1279
Act Celecoxib · DIN 02420155 · $0.1279
Apo-Celecoxib · DIN 02418932 · $0.1279
Bio-Celecoxib · DIN 02426382 · $0.1279
Celebrex · DIN 02239941 · $0.1279
Celecoxib · DIN 02429675 · $0.1279
Celecoxib · DIN 02436299 · $0.1279
Jamp-Celecoxib · DIN 02424533 · $0.1279
M-Celecoxib · DIN 02495465 · $0.1279
Mar-Celecoxib · DIN 02420058 · $0.1279
Mint-Celecoxib · DIN 02412497 · $0.1279
NRA-Celecoxib · DIN 02479737 · $0.1279
PMS-Celecoxib · DIN 02355442 · $0.1279
PMSC-Celecoxib · DIN 02517116 · $0.1279
Ran-Celecoxib · DIN 02412373 · $0.1279
Sdz Celecoxib · DIN 02442639 · $0.1279
Teva-Celecoxib · DIN 02288915 · $0.1279
Shortage status: resolved shortage (ended 2025-06-01); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02445670
Shortage record checked 2026-09-13T08:10:21.292534+00:00
Bio-Celecoxib · DIN 02426382 · 100mg · capsule
Limited Use — Reason for Use code 316, 317 requiredMarketed · checked 2026-09-02
Write on scriptLU code 316, 317 (patient must meet the criteria below)
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Ontario Limited Use criteria — code 316, 317
Coverage limit:
Osteoarthritis
Reason for Use code 316
For patients who have failed an adequate trial of acetaminophen (e.g. acetaminophen 1g QID for several weeks) and have had:
Coverage limit:
History of a documented, clinically significant ulcer or GI bleed; or
Failure or intolerance to at least three listed NSAIDS.
Coverage limit:
The maximum daily dose of celecoxib which will be reimbursed for the treatment of osteoarthritis is 200mg.
Coverage limit:
LU Authorization Period: 1 year
Coverage limit:
Rheumatoid arthritis
Reason for Use code 317
For patients who have had:
Coverage limit:
History of a documented, clinically significant ulcer or GI bleed; or
Failure or intolerance to at least three listed NSAIDS.
Coverage limit:
The maximum daily dose of celecoxib which will be reimbursed for the treatment of rheumatoid arthritis is 400mg.
Coverage limit:
LU Authorization Period: 1 year
Brand vs generic price
Lowest DBP recovery rule under medically necessary no-substitution claims:
6.2 Medically Necessary "No Substitution" Claims
The Side Effect Reporting Form will not have to be renewed. However, the
pharmacy must maintain a copy of the prescription that contains a direction that
there be no substitution and the required Health Canada Side Effect Reporting Form
(completed and signed by the prescriber). The prescriber must write “No
Substitution” or “No Sub” on renewal or subsequent new written prescriptions, and
indicate “No Substitution” on subsequent new oral prescriptions. The dispenser will
be reimbursed the DBP plus a mark-up and the lesser of the posted usual and
customary fee or the ODB dispensing fee minus the applicable ODB co-payment
amount. Where a completed Side Effect Reporting Form is not available at the
pharmacy during an inspection, the difference between the cost of the higher-cost
product and the lowest DBP listed for the interchangeable category will be
recovered.
(ontario.ca, Revision #17; 2026-08-03 ↗)
6.2 Medically Necessary "No Substitution" Claims
The Ministry will provide reimbursement of a higher-cost interchangeable product in
medically necessary circumstances where a patient has experienced a significant
adverse reaction with two (2) lower-cost interchangeable drug products, where
available. When a prescriber identifies a patient for which it is medically necessary
that a higher cost interchangeable product be provided, the prescriber must:
• Complete, sign and forward to the pharmacist a copy of the Health Canada
side effect reporting form for each lower-cost interchangeable drug product
trialed (Side Effect Reporting Form[s]); and
• Write “No Substitution” or “No Sub” on a written prescription or indicate “No
Substitution” to the pharmacist in the case of a verbal prescription.
The prescriber should keep a copy of the completed form in the patient’s record for
future use and reference.
In the case of a written prescription, when the pharmacist or dispensing physician
receives a prescription with the written notation “No Substitution” or “No Sub”,
reimbursement will be provided for the higher-cost interchangeable product only if
the prescription is accompanied by a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed.
This form must be completely filled out noting the details of the adverse reaction
and signed by the prescriber.
In the case of a verbal prescription, the prescriber must satisfy the operator of the
pharmacy or dispensing physician that a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed
has been completed and signed by the prescriber. A written record of this verbal
prescription and the completed Health Canada Side Effect Reporting Form must be
received by the pharmacy prior to claim submission.
Upon receipt, the pharmacist must:
• Fax, submit online or mail the completed and signed form to Health Canada’s
Canada Vigilance Program; and
• Retain his or her copy of the completed and signed Side Effect Reporting
Form.
(ontario.ca, Revision #17; 2026-08-03 ↗)1 brand, same coverage
Bio-Celecoxib · DIN 02426382
Manufacturer: Biomed Pharma; listing date 2016-02-25
Health Canada: Marketed since 2014-12-05 · brand BIO-CELECOXIB · ATC M01AH01 CELECOXIB · form Capsule · route Oral · ingredients CELECOXIB 100 MG · company Biomed pharma · schedule Prescription
Check this DIN again · Health Canada product recordBio-Celecoxib: Formulary list price $0.1279/unit (unit not stated in source; not the patient's cost)
Ministry pays: $0.1279 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=91097 · Verify on the e-Formulary ↗ (DIN 02426382)
Source record
DIN 02426382: Bio-Celecoxib
Raw flags: sec12=Y, sec3=Y
Item: 280804075; group id 377; item number 0898; lccId 00064; manufacturer id BMP
Source form: Cap; strength: 100mg
Recorded listing: Limited Use: paid only with a Reason for Use code and the criteria below
Source prices (unrounded): $0.1279; ministry $0.1279
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02426382
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=91097
Therapeutic Notes (formulary)
NSAIDs have a high rate of serious adverse effects in the elderly. When prescribing NSAIDs, the minimal effective dose for the shortest period of time should be used. In nonspecific pain and/or osteoarthritis, in the absence of joint inflammation (swelling), acetaminophen is a better first choice for analgesia. The most effective treatment to prevent NSAID-gastritis is misoprostol; although H-2 antagonists, such as ranitidine or cimetidine, are commonly used, they are not as effective. NSAIDs can significantly aggravate hypertension and congestive heart failure; ASA in doses below 1 gram per day is a better choice than other NSAID options if anti-inflammatory effects are required in patients with these conditions. Low dose ASA has additional benefits for anti-platelet indications that are not provided by other NSAIDs, and should be given in preference or in addition to other NSAIDs for patients with vascular indications.
Interchangeable products
AG-Celecoxib · DIN 02437570 · $0.1279
Act Celecoxib · DIN 02420155 · $0.1279
Apo-Celecoxib · DIN 02418932 · $0.1279
Auro-Celecoxib · DIN 02445670 · $0.1279
Celebrex · DIN 02239941 · $0.1279
Celecoxib · DIN 02429675 · $0.1279
Celecoxib · DIN 02436299 · $0.1279
Jamp-Celecoxib · DIN 02424533 · $0.1279
M-Celecoxib · DIN 02495465 · $0.1279
Mar-Celecoxib · DIN 02420058 · $0.1279
Mint-Celecoxib · DIN 02412497 · $0.1279
NRA-Celecoxib · DIN 02479737 · $0.1279
PMS-Celecoxib · DIN 02355442 · $0.1279
PMSC-Celecoxib · DIN 02517116 · $0.1279
Ran-Celecoxib · DIN 02412373 · $0.1279
Sdz Celecoxib · DIN 02442639 · $0.1279
Teva-Celecoxib · DIN 02288915 · $0.1279
Shortage status: resolved shortage (ended 2019-07-20); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02426382
Shortage record checked 2026-09-13T08:10:21.292534+00:00
Celebrex · DIN 02239941 · 100mg · capsule
Limited Use — Reason for Use code 316, 317 requiredMarketed · checked 2026-09-02
Write on scriptLU code 316, 317 (patient must meet the criteria below)
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Ontario Limited Use criteria — code 316, 317
Coverage limit:
Osteoarthritis
Reason for Use code 316
For patients who have failed an adequate trial of acetaminophen (e.g. acetaminophen 1g QID for several weeks) and have had:
Coverage limit:
History of a documented, clinically significant ulcer or GI bleed; or
Failure or intolerance to at least three listed NSAIDS.
Coverage limit:
The maximum daily dose of celecoxib which will be reimbursed for the treatment of osteoarthritis is 200mg.
Coverage limit:
LU Authorization Period: 1 year
Coverage limit:
Rheumatoid arthritis
Reason for Use code 317
For patients who have had:
Coverage limit:
History of a documented, clinically significant ulcer or GI bleed; or
Failure or intolerance to at least three listed NSAIDS.
Coverage limit:
The maximum daily dose of celecoxib which will be reimbursed for the treatment of rheumatoid arthritis is 400mg.
Coverage limit:
LU Authorization Period: 1 year
Savings card: RxHelp ONE lists Celebrex (read 2026-09-10) — brand-name savings card, free; cannot be combined with another card on the same claim.
(rxhelp.ca ↗)1 brand, same coverage
Celebrex · DIN 02239941
Manufacturer: Upjohn Canada ULC; listing date 2000-04-17
Health Canada: Marketed since 2023-09-26 · brand CELEBREX · ATC M01AH01 CELECOXIB · form Capsule · route Oral · ingredients CELECOXIB 100 MG · company Bgp pharma ulc · schedule Prescription
Check this DIN again · Health Canada product recordMinistry pays: $0.1279 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=63442 · Verify on the e-Formulary ↗ (DIN 02239941)
Source record
DIN 02239941: Celebrex
Raw flags: sec12=Y, sec3=Y
Item: 280804075; group id 377; item number 0898; lccId 00064; manufacturer id UJC
Source form: Cap; strength: 100mg
Recorded listing: Limited Use: paid only with a Reason for Use code and the criteria below
Source prices (unrounded): $0.8482; ministry $0.1279
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02239941
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=63442
Therapeutic Notes (formulary)
NSAIDs have a high rate of serious adverse effects in the elderly. When prescribing NSAIDs, the minimal effective dose for the shortest period of time should be used. In nonspecific pain and/or osteoarthritis, in the absence of joint inflammation (swelling), acetaminophen is a better first choice for analgesia. The most effective treatment to prevent NSAID-gastritis is misoprostol; although H-2 antagonists, such as ranitidine or cimetidine, are commonly used, they are not as effective. NSAIDs can significantly aggravate hypertension and congestive heart failure; ASA in doses below 1 gram per day is a better choice than other NSAID options if anti-inflammatory effects are required in patients with these conditions. Low dose ASA has additional benefits for anti-platelet indications that are not provided by other NSAIDs, and should be given in preference or in addition to other NSAIDs for patients with vascular indications.
Interchangeable products
AG-Celecoxib · DIN 02437570 · $0.1279
Act Celecoxib · DIN 02420155 · $0.1279
Apo-Celecoxib · DIN 02418932 · $0.1279
Auro-Celecoxib · DIN 02445670 · $0.1279
Bio-Celecoxib · DIN 02426382 · $0.1279
Celecoxib · DIN 02429675 · $0.1279
Celecoxib · DIN 02436299 · $0.1279
Jamp-Celecoxib · DIN 02424533 · $0.1279
M-Celecoxib · DIN 02495465 · $0.1279
Mar-Celecoxib · DIN 02420058 · $0.1279
Mint-Celecoxib · DIN 02412497 · $0.1279
NRA-Celecoxib · DIN 02479737 · $0.1279
PMS-Celecoxib · DIN 02355442 · $0.1279
PMSC-Celecoxib · DIN 02517116 · $0.1279
Ran-Celecoxib · DIN 02412373 · $0.1279
Sdz Celecoxib · DIN 02442639 · $0.1279
Teva-Celecoxib · DIN 02288915 · $0.1279
Shortage status: resolved shortage (ended 2017-06-01); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02239941
Shortage record checked 2026-09-13T08:10:21.292534+00:00
Celecoxib · DIN 02429675 · 100mg · capsule
Limited Use — Reason for Use code 316, 317 requiredMarketed · checked 2026-09-02
Write on scriptLU code 316, 317 (patient must meet the criteria below)
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Ontario Limited Use criteria — code 316, 317
Coverage limit:
Osteoarthritis
Reason for Use code 316
For patients who have failed an adequate trial of acetaminophen (e.g. acetaminophen 1g QID for several weeks) and have had:
Coverage limit:
History of a documented, clinically significant ulcer or GI bleed; or
Failure or intolerance to at least three listed NSAIDS.
Coverage limit:
The maximum daily dose of celecoxib which will be reimbursed for the treatment of osteoarthritis is 200mg.
Coverage limit:
LU Authorization Period: 1 year
Coverage limit:
Rheumatoid arthritis
Reason for Use code 317
For patients who have had:
Coverage limit:
History of a documented, clinically significant ulcer or GI bleed; or
Failure or intolerance to at least three listed NSAIDS.
Coverage limit:
The maximum daily dose of celecoxib which will be reimbursed for the treatment of rheumatoid arthritis is 400mg.
Coverage limit:
LU Authorization Period: 1 year
Brand vs generic price
Lowest DBP recovery rule under medically necessary no-substitution claims:
6.2 Medically Necessary "No Substitution" Claims
The Side Effect Reporting Form will not have to be renewed. However, the
pharmacy must maintain a copy of the prescription that contains a direction that
there be no substitution and the required Health Canada Side Effect Reporting Form
(completed and signed by the prescriber). The prescriber must write “No
Substitution” or “No Sub” on renewal or subsequent new written prescriptions, and
indicate “No Substitution” on subsequent new oral prescriptions. The dispenser will
be reimbursed the DBP plus a mark-up and the lesser of the posted usual and
customary fee or the ODB dispensing fee minus the applicable ODB co-payment
amount. Where a completed Side Effect Reporting Form is not available at the
pharmacy during an inspection, the difference between the cost of the higher-cost
product and the lowest DBP listed for the interchangeable category will be
recovered.
(ontario.ca, Revision #17; 2026-08-03 ↗)
6.2 Medically Necessary "No Substitution" Claims
The Ministry will provide reimbursement of a higher-cost interchangeable product in
medically necessary circumstances where a patient has experienced a significant
adverse reaction with two (2) lower-cost interchangeable drug products, where
available. When a prescriber identifies a patient for which it is medically necessary
that a higher cost interchangeable product be provided, the prescriber must:
• Complete, sign and forward to the pharmacist a copy of the Health Canada
side effect reporting form for each lower-cost interchangeable drug product
trialed (Side Effect Reporting Form[s]); and
• Write “No Substitution” or “No Sub” on a written prescription or indicate “No
Substitution” to the pharmacist in the case of a verbal prescription.
The prescriber should keep a copy of the completed form in the patient’s record for
future use and reference.
In the case of a written prescription, when the pharmacist or dispensing physician
receives a prescription with the written notation “No Substitution” or “No Sub”,
reimbursement will be provided for the higher-cost interchangeable product only if
the prescription is accompanied by a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed.
This form must be completely filled out noting the details of the adverse reaction
and signed by the prescriber.
In the case of a verbal prescription, the prescriber must satisfy the operator of the
pharmacy or dispensing physician that a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed
has been completed and signed by the prescriber. A written record of this verbal
prescription and the completed Health Canada Side Effect Reporting Form must be
received by the pharmacy prior to claim submission.
Upon receipt, the pharmacist must:
• Fax, submit online or mail the completed and signed form to Health Canada’s
Canada Vigilance Program; and
• Retain his or her copy of the completed and signed Side Effect Reporting
Form.
(ontario.ca, Revision #17; 2026-08-03 ↗)1 brand, same coverage
Celecoxib · DIN 02429675
Manufacturer: Sivem Pharmaceuticals ULC; listing date 2020-06-30
Health Canada: Marketed since 2018-07-04 · brand CELECOXIB · ATC M01AH01 CELECOXIB · form Capsule · route Oral · ingredients CELECOXIB 100 MG · company Sivem pharmaceuticals ulc · schedule Prescription
Check this DIN again · Health Canada product recordCelecoxib: Formulary list price $0.1279/unit (unit not stated in source; not the patient's cost)
Ministry pays: $0.1279 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=91412 · Verify on the e-Formulary ↗ (DIN 02429675)
Source record
DIN 02429675: Celecoxib
Raw flags: sec12=Y, sec3=Y
Item: 280804075; group id 377; item number 0898; lccId 00064; manufacturer id SIV
Source form: Cap; strength: 100mg
Recorded listing: Limited Use: paid only with a Reason for Use code and the criteria below
Source prices (unrounded): $0.1279; ministry $0.1279
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02429675
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=91412
Therapeutic Notes (formulary)
NSAIDs have a high rate of serious adverse effects in the elderly. When prescribing NSAIDs, the minimal effective dose for the shortest period of time should be used. In nonspecific pain and/or osteoarthritis, in the absence of joint inflammation (swelling), acetaminophen is a better first choice for analgesia. The most effective treatment to prevent NSAID-gastritis is misoprostol; although H-2 antagonists, such as ranitidine or cimetidine, are commonly used, they are not as effective. NSAIDs can significantly aggravate hypertension and congestive heart failure; ASA in doses below 1 gram per day is a better choice than other NSAID options if anti-inflammatory effects are required in patients with these conditions. Low dose ASA has additional benefits for anti-platelet indications that are not provided by other NSAIDs, and should be given in preference or in addition to other NSAIDs for patients with vascular indications.
Interchangeable products
AG-Celecoxib · DIN 02437570 · $0.1279
Act Celecoxib · DIN 02420155 · $0.1279
Apo-Celecoxib · DIN 02418932 · $0.1279
Auro-Celecoxib · DIN 02445670 · $0.1279
Bio-Celecoxib · DIN 02426382 · $0.1279
Celebrex · DIN 02239941 · $0.1279
Celecoxib · DIN 02436299 · $0.1279
Jamp-Celecoxib · DIN 02424533 · $0.1279
M-Celecoxib · DIN 02495465 · $0.1279
Mar-Celecoxib · DIN 02420058 · $0.1279
Mint-Celecoxib · DIN 02412497 · $0.1279
NRA-Celecoxib · DIN 02479737 · $0.1279
PMS-Celecoxib · DIN 02355442 · $0.1279
PMSC-Celecoxib · DIN 02517116 · $0.1279
Ran-Celecoxib · DIN 02412373 · $0.1279
Sdz Celecoxib · DIN 02442639 · $0.1279
Teva-Celecoxib · DIN 02288915 · $0.1279
Shortage status: resolved shortage (ended 2020-04-13); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02429675
Shortage record checked 2026-09-13T08:10:21.292534+00:00
Celecoxib · DIN 02436299 · 100mg · capsule
Limited Use — Reason for Use code 316, 317 requiredMarketed · checked 2026-09-02
Write on scriptLU code 316, 317 (patient must meet the criteria below)
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Ontario Limited Use criteria — code 316, 317
Coverage limit:
Osteoarthritis
Reason for Use code 316
For patients who have failed an adequate trial of acetaminophen (e.g. acetaminophen 1g QID for several weeks) and have had:
Coverage limit:
History of a documented, clinically significant ulcer or GI bleed; or
Failure or intolerance to at least three listed NSAIDS.
Coverage limit:
The maximum daily dose of celecoxib which will be reimbursed for the treatment of osteoarthritis is 200mg.
Coverage limit:
LU Authorization Period: 1 year
Coverage limit:
Rheumatoid arthritis
Reason for Use code 317
For patients who have had:
Coverage limit:
History of a documented, clinically significant ulcer or GI bleed; or
Failure or intolerance to at least three listed NSAIDS.
Coverage limit:
The maximum daily dose of celecoxib which will be reimbursed for the treatment of rheumatoid arthritis is 400mg.
Coverage limit:
LU Authorization Period: 1 year
Brand vs generic price
Lowest DBP recovery rule under medically necessary no-substitution claims:
6.2 Medically Necessary "No Substitution" Claims
The Side Effect Reporting Form will not have to be renewed. However, the
pharmacy must maintain a copy of the prescription that contains a direction that
there be no substitution and the required Health Canada Side Effect Reporting Form
(completed and signed by the prescriber). The prescriber must write “No
Substitution” or “No Sub” on renewal or subsequent new written prescriptions, and
indicate “No Substitution” on subsequent new oral prescriptions. The dispenser will
be reimbursed the DBP plus a mark-up and the lesser of the posted usual and
customary fee or the ODB dispensing fee minus the applicable ODB co-payment
amount. Where a completed Side Effect Reporting Form is not available at the
pharmacy during an inspection, the difference between the cost of the higher-cost
product and the lowest DBP listed for the interchangeable category will be
recovered.
(ontario.ca, Revision #17; 2026-08-03 ↗)
6.2 Medically Necessary "No Substitution" Claims
The Ministry will provide reimbursement of a higher-cost interchangeable product in
medically necessary circumstances where a patient has experienced a significant
adverse reaction with two (2) lower-cost interchangeable drug products, where
available. When a prescriber identifies a patient for which it is medically necessary
that a higher cost interchangeable product be provided, the prescriber must:
• Complete, sign and forward to the pharmacist a copy of the Health Canada
side effect reporting form for each lower-cost interchangeable drug product
trialed (Side Effect Reporting Form[s]); and
• Write “No Substitution” or “No Sub” on a written prescription or indicate “No
Substitution” to the pharmacist in the case of a verbal prescription.
The prescriber should keep a copy of the completed form in the patient’s record for
future use and reference.
In the case of a written prescription, when the pharmacist or dispensing physician
receives a prescription with the written notation “No Substitution” or “No Sub”,
reimbursement will be provided for the higher-cost interchangeable product only if
the prescription is accompanied by a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed.
This form must be completely filled out noting the details of the adverse reaction
and signed by the prescriber.
In the case of a verbal prescription, the prescriber must satisfy the operator of the
pharmacy or dispensing physician that a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed
has been completed and signed by the prescriber. A written record of this verbal
prescription and the completed Health Canada Side Effect Reporting Form must be
received by the pharmacy prior to claim submission.
Upon receipt, the pharmacist must:
• Fax, submit online or mail the completed and signed form to Health Canada’s
Canada Vigilance Program; and
• Retain his or her copy of the completed and signed Side Effect Reporting
Form.
(ontario.ca, Revision #17; 2026-08-03 ↗)1 brand, same coverage
Celecoxib · DIN 02436299
Manufacturer: Sanis Health Inc.; listing date 2021-03-29
Health Canada: Marketed since 2021-02-02 · brand CELECOXIB · ATC M01AH01 CELECOXIB · form Capsule · route Oral · ingredients CELECOXIB 100 MG · company Sanis health inc · schedule Prescription
Check this DIN again · Health Canada product recordCelecoxib: Formulary list price $0.1279/unit (unit not stated in source; not the patient's cost)
Ministry pays: $0.1279 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=92062 · Verify on the e-Formulary ↗ (DIN 02436299)
Source record
DIN 02436299: Celecoxib
Raw flags: sec12=Y, sec3=Y
Item: 280804075; group id 377; item number 0898; lccId 00064; manufacturer id SAI
Source form: Cap; strength: 100mg
Recorded listing: Limited Use: paid only with a Reason for Use code and the criteria below
Source prices (unrounded): $0.1279; ministry $0.1279
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02436299
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=92062
Therapeutic Notes (formulary)
NSAIDs have a high rate of serious adverse effects in the elderly. When prescribing NSAIDs, the minimal effective dose for the shortest period of time should be used. In nonspecific pain and/or osteoarthritis, in the absence of joint inflammation (swelling), acetaminophen is a better first choice for analgesia. The most effective treatment to prevent NSAID-gastritis is misoprostol; although H-2 antagonists, such as ranitidine or cimetidine, are commonly used, they are not as effective. NSAIDs can significantly aggravate hypertension and congestive heart failure; ASA in doses below 1 gram per day is a better choice than other NSAID options if anti-inflammatory effects are required in patients with these conditions. Low dose ASA has additional benefits for anti-platelet indications that are not provided by other NSAIDs, and should be given in preference or in addition to other NSAIDs for patients with vascular indications.
Interchangeable products
AG-Celecoxib · DIN 02437570 · $0.1279
Act Celecoxib · DIN 02420155 · $0.1279
Apo-Celecoxib · DIN 02418932 · $0.1279
Auro-Celecoxib · DIN 02445670 · $0.1279
Bio-Celecoxib · DIN 02426382 · $0.1279
Celebrex · DIN 02239941 · $0.1279
Celecoxib · DIN 02429675 · $0.1279
Jamp-Celecoxib · DIN 02424533 · $0.1279
M-Celecoxib · DIN 02495465 · $0.1279
Mar-Celecoxib · DIN 02420058 · $0.1279
Mint-Celecoxib · DIN 02412497 · $0.1279
NRA-Celecoxib · DIN 02479737 · $0.1279
PMS-Celecoxib · DIN 02355442 · $0.1279
PMSC-Celecoxib · DIN 02517116 · $0.1279
Ran-Celecoxib · DIN 02412373 · $0.1279
Sdz Celecoxib · DIN 02442639 · $0.1279
Teva-Celecoxib · DIN 02288915 · $0.1279
Shortage status: avoided shortage; reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02436299
Shortage record checked 2026-09-13T08:10:21.292534+00:00
Jamp-Celecoxib · DIN 02424533 · 100mg · capsule
Limited Use — Reason for Use code 316, 317 requiredMarketed · checked 2026-09-02
Write on scriptLU code 316, 317 (patient must meet the criteria below)
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Ontario Limited Use criteria — code 316, 317
Coverage limit:
Osteoarthritis
Reason for Use code 316
For patients who have failed an adequate trial of acetaminophen (e.g. acetaminophen 1g QID for several weeks) and have had:
Coverage limit:
History of a documented, clinically significant ulcer or GI bleed; or
Failure or intolerance to at least three listed NSAIDS.
Coverage limit:
The maximum daily dose of celecoxib which will be reimbursed for the treatment of osteoarthritis is 200mg.
Coverage limit:
LU Authorization Period: 1 year
Coverage limit:
Rheumatoid arthritis
Reason for Use code 317
For patients who have had:
Coverage limit:
History of a documented, clinically significant ulcer or GI bleed; or
Failure or intolerance to at least three listed NSAIDS.
Coverage limit:
The maximum daily dose of celecoxib which will be reimbursed for the treatment of rheumatoid arthritis is 400mg.
Coverage limit:
LU Authorization Period: 1 year
Brand vs generic price
Lowest DBP recovery rule under medically necessary no-substitution claims:
6.2 Medically Necessary "No Substitution" Claims
The Side Effect Reporting Form will not have to be renewed. However, the
pharmacy must maintain a copy of the prescription that contains a direction that
there be no substitution and the required Health Canada Side Effect Reporting Form
(completed and signed by the prescriber). The prescriber must write “No
Substitution” or “No Sub” on renewal or subsequent new written prescriptions, and
indicate “No Substitution” on subsequent new oral prescriptions. The dispenser will
be reimbursed the DBP plus a mark-up and the lesser of the posted usual and
customary fee or the ODB dispensing fee minus the applicable ODB co-payment
amount. Where a completed Side Effect Reporting Form is not available at the
pharmacy during an inspection, the difference between the cost of the higher-cost
product and the lowest DBP listed for the interchangeable category will be
recovered.
(ontario.ca, Revision #17; 2026-08-03 ↗)
6.2 Medically Necessary "No Substitution" Claims
The Ministry will provide reimbursement of a higher-cost interchangeable product in
medically necessary circumstances where a patient has experienced a significant
adverse reaction with two (2) lower-cost interchangeable drug products, where
available. When a prescriber identifies a patient for which it is medically necessary
that a higher cost interchangeable product be provided, the prescriber must:
• Complete, sign and forward to the pharmacist a copy of the Health Canada
side effect reporting form for each lower-cost interchangeable drug product
trialed (Side Effect Reporting Form[s]); and
• Write “No Substitution” or “No Sub” on a written prescription or indicate “No
Substitution” to the pharmacist in the case of a verbal prescription.
The prescriber should keep a copy of the completed form in the patient’s record for
future use and reference.
In the case of a written prescription, when the pharmacist or dispensing physician
receives a prescription with the written notation “No Substitution” or “No Sub”,
reimbursement will be provided for the higher-cost interchangeable product only if
the prescription is accompanied by a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed.
This form must be completely filled out noting the details of the adverse reaction
and signed by the prescriber.
In the case of a verbal prescription, the prescriber must satisfy the operator of the
pharmacy or dispensing physician that a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed
has been completed and signed by the prescriber. A written record of this verbal
prescription and the completed Health Canada Side Effect Reporting Form must be
received by the pharmacy prior to claim submission.
Upon receipt, the pharmacist must:
• Fax, submit online or mail the completed and signed form to Health Canada’s
Canada Vigilance Program; and
• Retain his or her copy of the completed and signed Side Effect Reporting
Form.
(ontario.ca, Revision #17; 2026-08-03 ↗)1 brand, same coverage
Jamp-Celecoxib · DIN 02424533
Manufacturer: Jamp Pharma Corporation; listing date 2015-01-28
Health Canada: Marketed since 2026-03-12 · brand JAMP CELECOXIB · ATC M01AH01 CELECOXIB · form Capsule · route Oral · ingredients CELECOXIB 100 MG · company Jamp pharma corporation · schedule Prescription
Check this DIN again · Health Canada product recordJamp-Celecoxib: Formulary list price $0.1279/unit (unit not stated in source; not the patient's cost)
Ministry pays: $0.1279 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=90922 · Verify on the e-Formulary ↗ (DIN 02424533)
Source record
DIN 02424533: Jamp-Celecoxib
Raw flags: sec12=Y, sec3=Y
Item: 280804075; group id 377; item number 0898; lccId 00064; manufacturer id JPC
Source form: Cap; strength: 100mg
Recorded listing: Limited Use: paid only with a Reason for Use code and the criteria below
Source prices (unrounded): $0.1279; ministry $0.1279
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02424533
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=90922
Therapeutic Notes (formulary)
NSAIDs have a high rate of serious adverse effects in the elderly. When prescribing NSAIDs, the minimal effective dose for the shortest period of time should be used. In nonspecific pain and/or osteoarthritis, in the absence of joint inflammation (swelling), acetaminophen is a better first choice for analgesia. The most effective treatment to prevent NSAID-gastritis is misoprostol; although H-2 antagonists, such as ranitidine or cimetidine, are commonly used, they are not as effective. NSAIDs can significantly aggravate hypertension and congestive heart failure; ASA in doses below 1 gram per day is a better choice than other NSAID options if anti-inflammatory effects are required in patients with these conditions. Low dose ASA has additional benefits for anti-platelet indications that are not provided by other NSAIDs, and should be given in preference or in addition to other NSAIDs for patients with vascular indications.
Interchangeable products
AG-Celecoxib · DIN 02437570 · $0.1279
Act Celecoxib · DIN 02420155 · $0.1279
Apo-Celecoxib · DIN 02418932 · $0.1279
Auro-Celecoxib · DIN 02445670 · $0.1279
Bio-Celecoxib · DIN 02426382 · $0.1279
Celebrex · DIN 02239941 · $0.1279
Celecoxib · DIN 02429675 · $0.1279
Celecoxib · DIN 02436299 · $0.1279
M-Celecoxib · DIN 02495465 · $0.1279
Mar-Celecoxib · DIN 02420058 · $0.1279
Mint-Celecoxib · DIN 02412497 · $0.1279
NRA-Celecoxib · DIN 02479737 · $0.1279
PMS-Celecoxib · DIN 02355442 · $0.1279
PMSC-Celecoxib · DIN 02517116 · $0.1279
Ran-Celecoxib · DIN 02412373 · $0.1279
Sdz Celecoxib · DIN 02442639 · $0.1279
Teva-Celecoxib · DIN 02288915 · $0.1279
Shortage status: resolved shortage (ended 2023-09-26); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02424533
Shortage record checked 2026-09-13T08:10:21.292534+00:00
M-Celecoxib · DIN 02495465 · 100mg · capsule
Limited Use — Reason for Use code 316, 317 requiredMarketed · checked 2026-09-02
Write on scriptLU code 316, 317 (patient must meet the criteria below)
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Ontario Limited Use criteria — code 316, 317
Coverage limit:
Osteoarthritis
Reason for Use code 316
For patients who have failed an adequate trial of acetaminophen (e.g. acetaminophen 1g QID for several weeks) and have had:
Coverage limit:
History of a documented, clinically significant ulcer or GI bleed; or
Failure or intolerance to at least three listed NSAIDS.
Coverage limit:
The maximum daily dose of celecoxib which will be reimbursed for the treatment of osteoarthritis is 200mg.
Coverage limit:
LU Authorization Period: 1 year
Coverage limit:
Rheumatoid arthritis
Reason for Use code 317
For patients who have had:
Coverage limit:
History of a documented, clinically significant ulcer or GI bleed; or
Failure or intolerance to at least three listed NSAIDS.
Coverage limit:
The maximum daily dose of celecoxib which will be reimbursed for the treatment of rheumatoid arthritis is 400mg.
Coverage limit:
LU Authorization Period: 1 year
Brand vs generic price
Lowest DBP recovery rule under medically necessary no-substitution claims:
6.2 Medically Necessary "No Substitution" Claims
The Side Effect Reporting Form will not have to be renewed. However, the
pharmacy must maintain a copy of the prescription that contains a direction that
there be no substitution and the required Health Canada Side Effect Reporting Form
(completed and signed by the prescriber). The prescriber must write “No
Substitution” or “No Sub” on renewal or subsequent new written prescriptions, and
indicate “No Substitution” on subsequent new oral prescriptions. The dispenser will
be reimbursed the DBP plus a mark-up and the lesser of the posted usual and
customary fee or the ODB dispensing fee minus the applicable ODB co-payment
amount. Where a completed Side Effect Reporting Form is not available at the
pharmacy during an inspection, the difference between the cost of the higher-cost
product and the lowest DBP listed for the interchangeable category will be
recovered.
(ontario.ca, Revision #17; 2026-08-03 ↗)
6.2 Medically Necessary "No Substitution" Claims
The Ministry will provide reimbursement of a higher-cost interchangeable product in
medically necessary circumstances where a patient has experienced a significant
adverse reaction with two (2) lower-cost interchangeable drug products, where
available. When a prescriber identifies a patient for which it is medically necessary
that a higher cost interchangeable product be provided, the prescriber must:
• Complete, sign and forward to the pharmacist a copy of the Health Canada
side effect reporting form for each lower-cost interchangeable drug product
trialed (Side Effect Reporting Form[s]); and
• Write “No Substitution” or “No Sub” on a written prescription or indicate “No
Substitution” to the pharmacist in the case of a verbal prescription.
The prescriber should keep a copy of the completed form in the patient’s record for
future use and reference.
In the case of a written prescription, when the pharmacist or dispensing physician
receives a prescription with the written notation “No Substitution” or “No Sub”,
reimbursement will be provided for the higher-cost interchangeable product only if
the prescription is accompanied by a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed.
This form must be completely filled out noting the details of the adverse reaction
and signed by the prescriber.
In the case of a verbal prescription, the prescriber must satisfy the operator of the
pharmacy or dispensing physician that a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed
has been completed and signed by the prescriber. A written record of this verbal
prescription and the completed Health Canada Side Effect Reporting Form must be
received by the pharmacy prior to claim submission.
Upon receipt, the pharmacist must:
• Fax, submit online or mail the completed and signed form to Health Canada’s
Canada Vigilance Program; and
• Retain his or her copy of the completed and signed Side Effect Reporting
Form.
(ontario.ca, Revision #17; 2026-08-03 ↗)1 brand, same coverage
M-Celecoxib · DIN 02495465
Manufacturer: Mantra Pharma Inc.; listing date 2021-10-29
Health Canada: Marketed since 2020-03-24 · brand M-CELECOXIB · ATC M01AH01 CELECOXIB · form Capsule · route Oral · ingredients CELECOXIB 100 MG · company Mantra pharma inc · schedule Prescription
Check this DIN again · Health Canada product recordM-Celecoxib: Formulary list price $0.1279/unit (unit not stated in source; not the patient's cost)
Ministry pays: $0.1279 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=98538 · Verify on the e-Formulary ↗ (DIN 02495465)
Source record
DIN 02495465: M-Celecoxib
Raw flags: sec12=Y, sec3=Y
Item: 280804075; group id 377; item number 0898; lccId 00064; manufacturer id MAT
Source form: Cap; strength: 100mg
Recorded listing: Limited Use: paid only with a Reason for Use code and the criteria below
Source prices (unrounded): $0.1279; ministry $0.1279
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02495465
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=98538
Therapeutic Notes (formulary)
NSAIDs have a high rate of serious adverse effects in the elderly. When prescribing NSAIDs, the minimal effective dose for the shortest period of time should be used. In nonspecific pain and/or osteoarthritis, in the absence of joint inflammation (swelling), acetaminophen is a better first choice for analgesia. The most effective treatment to prevent NSAID-gastritis is misoprostol; although H-2 antagonists, such as ranitidine or cimetidine, are commonly used, they are not as effective. NSAIDs can significantly aggravate hypertension and congestive heart failure; ASA in doses below 1 gram per day is a better choice than other NSAID options if anti-inflammatory effects are required in patients with these conditions. Low dose ASA has additional benefits for anti-platelet indications that are not provided by other NSAIDs, and should be given in preference or in addition to other NSAIDs for patients with vascular indications.
Interchangeable products
AG-Celecoxib · DIN 02437570 · $0.1279
Act Celecoxib · DIN 02420155 · $0.1279
Apo-Celecoxib · DIN 02418932 · $0.1279
Auro-Celecoxib · DIN 02445670 · $0.1279
Bio-Celecoxib · DIN 02426382 · $0.1279
Celebrex · DIN 02239941 · $0.1279
Celecoxib · DIN 02429675 · $0.1279
Celecoxib · DIN 02436299 · $0.1279
Jamp-Celecoxib · DIN 02424533 · $0.1279
Mar-Celecoxib · DIN 02420058 · $0.1279
Mint-Celecoxib · DIN 02412497 · $0.1279
NRA-Celecoxib · DIN 02479737 · $0.1279
PMS-Celecoxib · DIN 02355442 · $0.1279
PMSC-Celecoxib · DIN 02517116 · $0.1279
Ran-Celecoxib · DIN 02412373 · $0.1279
Sdz Celecoxib · DIN 02442639 · $0.1279
Teva-Celecoxib · DIN 02288915 · $0.1279
Shortage status: resolved shortage (ended 2026-06-22); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02495465
Shortage record checked 2026-09-13T08:10:21.292534+00:00
Mar-Celecoxib · DIN 02420058 · 100mg · capsule
Limited Use — Reason for Use code 316, 317 requiredMarketed · checked 2026-09-02
Write on scriptLU code 316, 317 (patient must meet the criteria below)
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Ontario Limited Use criteria — code 316, 317
Coverage limit:
Osteoarthritis
Reason for Use code 316
For patients who have failed an adequate trial of acetaminophen (e.g. acetaminophen 1g QID for several weeks) and have had:
Coverage limit:
History of a documented, clinically significant ulcer or GI bleed; or
Failure or intolerance to at least three listed NSAIDS.
Coverage limit:
The maximum daily dose of celecoxib which will be reimbursed for the treatment of osteoarthritis is 200mg.
Coverage limit:
LU Authorization Period: 1 year
Coverage limit:
Rheumatoid arthritis
Reason for Use code 317
For patients who have had:
Coverage limit:
History of a documented, clinically significant ulcer or GI bleed; or
Failure or intolerance to at least three listed NSAIDS.
Coverage limit:
The maximum daily dose of celecoxib which will be reimbursed for the treatment of rheumatoid arthritis is 400mg.
Coverage limit:
LU Authorization Period: 1 year
Brand vs generic price
Lowest DBP recovery rule under medically necessary no-substitution claims:
6.2 Medically Necessary "No Substitution" Claims
The Side Effect Reporting Form will not have to be renewed. However, the
pharmacy must maintain a copy of the prescription that contains a direction that
there be no substitution and the required Health Canada Side Effect Reporting Form
(completed and signed by the prescriber). The prescriber must write “No
Substitution” or “No Sub” on renewal or subsequent new written prescriptions, and
indicate “No Substitution” on subsequent new oral prescriptions. The dispenser will
be reimbursed the DBP plus a mark-up and the lesser of the posted usual and
customary fee or the ODB dispensing fee minus the applicable ODB co-payment
amount. Where a completed Side Effect Reporting Form is not available at the
pharmacy during an inspection, the difference between the cost of the higher-cost
product and the lowest DBP listed for the interchangeable category will be
recovered.
(ontario.ca, Revision #17; 2026-08-03 ↗)
6.2 Medically Necessary "No Substitution" Claims
The Ministry will provide reimbursement of a higher-cost interchangeable product in
medically necessary circumstances where a patient has experienced a significant
adverse reaction with two (2) lower-cost interchangeable drug products, where
available. When a prescriber identifies a patient for which it is medically necessary
that a higher cost interchangeable product be provided, the prescriber must:
• Complete, sign and forward to the pharmacist a copy of the Health Canada
side effect reporting form for each lower-cost interchangeable drug product
trialed (Side Effect Reporting Form[s]); and
• Write “No Substitution” or “No Sub” on a written prescription or indicate “No
Substitution” to the pharmacist in the case of a verbal prescription.
The prescriber should keep a copy of the completed form in the patient’s record for
future use and reference.
In the case of a written prescription, when the pharmacist or dispensing physician
receives a prescription with the written notation “No Substitution” or “No Sub”,
reimbursement will be provided for the higher-cost interchangeable product only if
the prescription is accompanied by a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed.
This form must be completely filled out noting the details of the adverse reaction
and signed by the prescriber.
In the case of a verbal prescription, the prescriber must satisfy the operator of the
pharmacy or dispensing physician that a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed
has been completed and signed by the prescriber. A written record of this verbal
prescription and the completed Health Canada Side Effect Reporting Form must be
received by the pharmacy prior to claim submission.
Upon receipt, the pharmacist must:
• Fax, submit online or mail the completed and signed form to Health Canada’s
Canada Vigilance Program; and
• Retain his or her copy of the completed and signed Side Effect Reporting
Form.
(ontario.ca, Revision #17; 2026-08-03 ↗)1 brand, same coverage
Mar-Celecoxib · DIN 02420058
Manufacturer: Marcan Pharmaceuticals Inc.; listing date 2015-01-28
Health Canada: Marketed since 2014-11-17 · brand MAR-CELECOXIB · ATC M01AH01 CELECOXIB · form Capsule · route Oral · ingredients CELECOXIB 100 MG · company Marcan pharmaceuticals inc · schedule Prescription
Check this DIN again · Health Canada product recordMar-Celecoxib: Formulary list price $0.1279/unit (unit not stated in source; not the patient's cost)
Ministry pays: $0.1279 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=90466 · Verify on the e-Formulary ↗ (DIN 02420058)
Source record
DIN 02420058: Mar-Celecoxib
Raw flags: sec12=Y, sec3=Y
Item: 280804075; group id 377; item number 0898; lccId 00064; manufacturer id MAR
Source form: Cap; strength: 100mg
Recorded listing: Limited Use: paid only with a Reason for Use code and the criteria below
Source prices (unrounded): $0.1279; ministry $0.1279
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02420058
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=90466
Therapeutic Notes (formulary)
NSAIDs have a high rate of serious adverse effects in the elderly. When prescribing NSAIDs, the minimal effective dose for the shortest period of time should be used. In nonspecific pain and/or osteoarthritis, in the absence of joint inflammation (swelling), acetaminophen is a better first choice for analgesia. The most effective treatment to prevent NSAID-gastritis is misoprostol; although H-2 antagonists, such as ranitidine or cimetidine, are commonly used, they are not as effective. NSAIDs can significantly aggravate hypertension and congestive heart failure; ASA in doses below 1 gram per day is a better choice than other NSAID options if anti-inflammatory effects are required in patients with these conditions. Low dose ASA has additional benefits for anti-platelet indications that are not provided by other NSAIDs, and should be given in preference or in addition to other NSAIDs for patients with vascular indications.
Interchangeable products
AG-Celecoxib · DIN 02437570 · $0.1279
Act Celecoxib · DIN 02420155 · $0.1279
Apo-Celecoxib · DIN 02418932 · $0.1279
Auro-Celecoxib · DIN 02445670 · $0.1279
Bio-Celecoxib · DIN 02426382 · $0.1279
Celebrex · DIN 02239941 · $0.1279
Celecoxib · DIN 02429675 · $0.1279
Celecoxib · DIN 02436299 · $0.1279
Jamp-Celecoxib · DIN 02424533 · $0.1279
M-Celecoxib · DIN 02495465 · $0.1279
Mint-Celecoxib · DIN 02412497 · $0.1279
NRA-Celecoxib · DIN 02479737 · $0.1279
PMS-Celecoxib · DIN 02355442 · $0.1279
PMSC-Celecoxib · DIN 02517116 · $0.1279
Ran-Celecoxib · DIN 02412373 · $0.1279
Sdz Celecoxib · DIN 02442639 · $0.1279
Teva-Celecoxib · DIN 02288915 · $0.1279
Shortage status: resolved shortage (ended 2018-09-13); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02420058
Shortage record checked 2026-09-13T08:10:21.292534+00:00
Mint-Celecoxib · DIN 02412497 · 100mg · capsule
Limited Use — Reason for Use code 316, 317 requiredMarketed · checked 2026-09-02
Write on scriptLU code 316, 317 (patient must meet the criteria below)
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Ontario Limited Use criteria — code 316, 317
Coverage limit:
Osteoarthritis
Reason for Use code 316
For patients who have failed an adequate trial of acetaminophen (e.g. acetaminophen 1g QID for several weeks) and have had:
Coverage limit:
History of a documented, clinically significant ulcer or GI bleed; or
Failure or intolerance to at least three listed NSAIDS.
Coverage limit:
The maximum daily dose of celecoxib which will be reimbursed for the treatment of osteoarthritis is 200mg.
Coverage limit:
LU Authorization Period: 1 year
Coverage limit:
Rheumatoid arthritis
Reason for Use code 317
For patients who have had:
Coverage limit:
History of a documented, clinically significant ulcer or GI bleed; or
Failure or intolerance to at least three listed NSAIDS.
Coverage limit:
The maximum daily dose of celecoxib which will be reimbursed for the treatment of rheumatoid arthritis is 400mg.
Coverage limit:
LU Authorization Period: 1 year
Brand vs generic price
Lowest DBP recovery rule under medically necessary no-substitution claims:
6.2 Medically Necessary "No Substitution" Claims
The Side Effect Reporting Form will not have to be renewed. However, the
pharmacy must maintain a copy of the prescription that contains a direction that
there be no substitution and the required Health Canada Side Effect Reporting Form
(completed and signed by the prescriber). The prescriber must write “No
Substitution” or “No Sub” on renewal or subsequent new written prescriptions, and
indicate “No Substitution” on subsequent new oral prescriptions. The dispenser will
be reimbursed the DBP plus a mark-up and the lesser of the posted usual and
customary fee or the ODB dispensing fee minus the applicable ODB co-payment
amount. Where a completed Side Effect Reporting Form is not available at the
pharmacy during an inspection, the difference between the cost of the higher-cost
product and the lowest DBP listed for the interchangeable category will be
recovered.
(ontario.ca, Revision #17; 2026-08-03 ↗)
6.2 Medically Necessary "No Substitution" Claims
The Ministry will provide reimbursement of a higher-cost interchangeable product in
medically necessary circumstances where a patient has experienced a significant
adverse reaction with two (2) lower-cost interchangeable drug products, where
available. When a prescriber identifies a patient for which it is medically necessary
that a higher cost interchangeable product be provided, the prescriber must:
• Complete, sign and forward to the pharmacist a copy of the Health Canada
side effect reporting form for each lower-cost interchangeable drug product
trialed (Side Effect Reporting Form[s]); and
• Write “No Substitution” or “No Sub” on a written prescription or indicate “No
Substitution” to the pharmacist in the case of a verbal prescription.
The prescriber should keep a copy of the completed form in the patient’s record for
future use and reference.
In the case of a written prescription, when the pharmacist or dispensing physician
receives a prescription with the written notation “No Substitution” or “No Sub”,
reimbursement will be provided for the higher-cost interchangeable product only if
the prescription is accompanied by a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed.
This form must be completely filled out noting the details of the adverse reaction
and signed by the prescriber.
In the case of a verbal prescription, the prescriber must satisfy the operator of the
pharmacy or dispensing physician that a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed
has been completed and signed by the prescriber. A written record of this verbal
prescription and the completed Health Canada Side Effect Reporting Form must be
received by the pharmacy prior to claim submission.
Upon receipt, the pharmacist must:
• Fax, submit online or mail the completed and signed form to Health Canada’s
Canada Vigilance Program; and
• Retain his or her copy of the completed and signed Side Effect Reporting
Form.
(ontario.ca, Revision #17; 2026-08-03 ↗)1 brand, same coverage
Mint-Celecoxib · DIN 02412497
Manufacturer: Mint Pharmaceuticals Inc.; listing date 2015-01-28
Health Canada: Marketed since 2014-11-17 · brand MINT-CELECOXIB · ATC M01AH01 CELECOXIB · form Capsule · route Oral · ingredients CELECOXIB 100 MG · company Mint pharmaceuticals inc · schedule Prescription
Check this DIN again · Health Canada product recordMint-Celecoxib: Formulary list price $0.1279/unit (unit not stated in source; not the patient's cost)
Ministry pays: $0.1279 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=89713 · Verify on the e-Formulary ↗ (DIN 02412497)
Source record
DIN 02412497: Mint-Celecoxib
Raw flags: sec12=Y, sec3=Y
Item: 280804075; group id 377; item number 0898; lccId 00064; manufacturer id MIN
Source form: Cap; strength: 100mg
Recorded listing: Limited Use: paid only with a Reason for Use code and the criteria below
Source prices (unrounded): $0.1279; ministry $0.1279
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02412497
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=89713
Therapeutic Notes (formulary)
NSAIDs have a high rate of serious adverse effects in the elderly. When prescribing NSAIDs, the minimal effective dose for the shortest period of time should be used. In nonspecific pain and/or osteoarthritis, in the absence of joint inflammation (swelling), acetaminophen is a better first choice for analgesia. The most effective treatment to prevent NSAID-gastritis is misoprostol; although H-2 antagonists, such as ranitidine or cimetidine, are commonly used, they are not as effective. NSAIDs can significantly aggravate hypertension and congestive heart failure; ASA in doses below 1 gram per day is a better choice than other NSAID options if anti-inflammatory effects are required in patients with these conditions. Low dose ASA has additional benefits for anti-platelet indications that are not provided by other NSAIDs, and should be given in preference or in addition to other NSAIDs for patients with vascular indications.
Interchangeable products
AG-Celecoxib · DIN 02437570 · $0.1279
Act Celecoxib · DIN 02420155 · $0.1279
Apo-Celecoxib · DIN 02418932 · $0.1279
Auro-Celecoxib · DIN 02445670 · $0.1279
Bio-Celecoxib · DIN 02426382 · $0.1279
Celebrex · DIN 02239941 · $0.1279
Celecoxib · DIN 02429675 · $0.1279
Celecoxib · DIN 02436299 · $0.1279
Jamp-Celecoxib · DIN 02424533 · $0.1279
M-Celecoxib · DIN 02495465 · $0.1279
Mar-Celecoxib · DIN 02420058 · $0.1279
NRA-Celecoxib · DIN 02479737 · $0.1279
PMS-Celecoxib · DIN 02355442 · $0.1279
PMSC-Celecoxib · DIN 02517116 · $0.1279
Ran-Celecoxib · DIN 02412373 · $0.1279
Sdz Celecoxib · DIN 02442639 · $0.1279
Teva-Celecoxib · DIN 02288915 · $0.1279
Shortage status: no shortage or discontinuation reported (checked 2026-09-13T08:10:21.292534+00:00); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02412497
Shortage record checked 2026-09-13T08:10:21.292534+00:00
NRA-Celecoxib · DIN 02479737 · 100mg · capsule
Limited Use — Reason for Use code 316, 317 requiredMarketed · checked 2026-09-02
Write on scriptLU code 316, 317 (patient must meet the criteria below)
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Ontario Limited Use criteria — code 316, 317
Coverage limit:
Osteoarthritis
Reason for Use code 316
For patients who have failed an adequate trial of acetaminophen (e.g. acetaminophen 1g QID for several weeks) and have had:
Coverage limit:
History of a documented, clinically significant ulcer or GI bleed; or
Failure or intolerance to at least three listed NSAIDS.
Coverage limit:
The maximum daily dose of celecoxib which will be reimbursed for the treatment of osteoarthritis is 200mg.
Coverage limit:
LU Authorization Period: 1 year
Coverage limit:
Rheumatoid arthritis
Reason for Use code 317
For patients who have had:
Coverage limit:
History of a documented, clinically significant ulcer or GI bleed; or
Failure or intolerance to at least three listed NSAIDS.
Coverage limit:
The maximum daily dose of celecoxib which will be reimbursed for the treatment of rheumatoid arthritis is 400mg.
Coverage limit:
LU Authorization Period: 1 year
Brand vs generic price
Lowest DBP recovery rule under medically necessary no-substitution claims:
6.2 Medically Necessary "No Substitution" Claims
The Side Effect Reporting Form will not have to be renewed. However, the
pharmacy must maintain a copy of the prescription that contains a direction that
there be no substitution and the required Health Canada Side Effect Reporting Form
(completed and signed by the prescriber). The prescriber must write “No
Substitution” or “No Sub” on renewal or subsequent new written prescriptions, and
indicate “No Substitution” on subsequent new oral prescriptions. The dispenser will
be reimbursed the DBP plus a mark-up and the lesser of the posted usual and
customary fee or the ODB dispensing fee minus the applicable ODB co-payment
amount. Where a completed Side Effect Reporting Form is not available at the
pharmacy during an inspection, the difference between the cost of the higher-cost
product and the lowest DBP listed for the interchangeable category will be
recovered.
(ontario.ca, Revision #17; 2026-08-03 ↗)
6.2 Medically Necessary "No Substitution" Claims
The Ministry will provide reimbursement of a higher-cost interchangeable product in
medically necessary circumstances where a patient has experienced a significant
adverse reaction with two (2) lower-cost interchangeable drug products, where
available. When a prescriber identifies a patient for which it is medically necessary
that a higher cost interchangeable product be provided, the prescriber must:
• Complete, sign and forward to the pharmacist a copy of the Health Canada
side effect reporting form for each lower-cost interchangeable drug product
trialed (Side Effect Reporting Form[s]); and
• Write “No Substitution” or “No Sub” on a written prescription or indicate “No
Substitution” to the pharmacist in the case of a verbal prescription.
The prescriber should keep a copy of the completed form in the patient’s record for
future use and reference.
In the case of a written prescription, when the pharmacist or dispensing physician
receives a prescription with the written notation “No Substitution” or “No Sub”,
reimbursement will be provided for the higher-cost interchangeable product only if
the prescription is accompanied by a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed.
This form must be completely filled out noting the details of the adverse reaction
and signed by the prescriber.
In the case of a verbal prescription, the prescriber must satisfy the operator of the
pharmacy or dispensing physician that a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed
has been completed and signed by the prescriber. A written record of this verbal
prescription and the completed Health Canada Side Effect Reporting Form must be
received by the pharmacy prior to claim submission.
Upon receipt, the pharmacist must:
• Fax, submit online or mail the completed and signed form to Health Canada’s
Canada Vigilance Program; and
• Retain his or her copy of the completed and signed Side Effect Reporting
Form.
(ontario.ca, Revision #17; 2026-08-03 ↗)1 brand, same coverage
NRA-Celecoxib · DIN 02479737
Manufacturer: Nora Pharma; listing date 2020-06-30
Health Canada: Marketed since 2019-07-02 · brand NRA-CELECOXIB · ATC M01AH01 CELECOXIB · form Capsule · route Oral · ingredients CELECOXIB 100 MG · company Nora pharma inc · schedule Prescription
Check this DIN again · Health Canada product recordNRA-Celecoxib: Formulary list price $0.1279/unit (unit not stated in source; not the patient's cost)
Ministry pays: $0.1279 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=97003 · Verify on the e-Formulary ↗ (DIN 02479737)
Source record
DIN 02479737: NRA-Celecoxib
Raw flags: sec12=Y, sec3=Y
Item: 280804075; group id 377; item number 0898; lccId 00064; manufacturer id NRA
Source form: Cap; strength: 100mg
Recorded listing: Limited Use: paid only with a Reason for Use code and the criteria below
Source prices (unrounded): $0.1279; ministry $0.1279
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02479737
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=97003
Therapeutic Notes (formulary)
NSAIDs have a high rate of serious adverse effects in the elderly. When prescribing NSAIDs, the minimal effective dose for the shortest period of time should be used. In nonspecific pain and/or osteoarthritis, in the absence of joint inflammation (swelling), acetaminophen is a better first choice for analgesia. The most effective treatment to prevent NSAID-gastritis is misoprostol; although H-2 antagonists, such as ranitidine or cimetidine, are commonly used, they are not as effective. NSAIDs can significantly aggravate hypertension and congestive heart failure; ASA in doses below 1 gram per day is a better choice than other NSAID options if anti-inflammatory effects are required in patients with these conditions. Low dose ASA has additional benefits for anti-platelet indications that are not provided by other NSAIDs, and should be given in preference or in addition to other NSAIDs for patients with vascular indications.
Interchangeable products
AG-Celecoxib · DIN 02437570 · $0.1279
Act Celecoxib · DIN 02420155 · $0.1279
Apo-Celecoxib · DIN 02418932 · $0.1279
Auro-Celecoxib · DIN 02445670 · $0.1279
Bio-Celecoxib · DIN 02426382 · $0.1279
Celebrex · DIN 02239941 · $0.1279
Celecoxib · DIN 02429675 · $0.1279
Celecoxib · DIN 02436299 · $0.1279
Jamp-Celecoxib · DIN 02424533 · $0.1279
M-Celecoxib · DIN 02495465 · $0.1279
Mar-Celecoxib · DIN 02420058 · $0.1279
Mint-Celecoxib · DIN 02412497 · $0.1279
PMS-Celecoxib · DIN 02355442 · $0.1279
PMSC-Celecoxib · DIN 02517116 · $0.1279
Ran-Celecoxib · DIN 02412373 · $0.1279
Sdz Celecoxib · DIN 02442639 · $0.1279
Teva-Celecoxib · DIN 02288915 · $0.1279
Shortage status: no shortage or discontinuation reported (checked 2026-09-13T08:10:21.292534+00:00); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02479737
Shortage record checked 2026-09-13T08:10:21.292534+00:00
PMSC-Celecoxib · DIN 02517116 · 100mg · capsule
Limited Use — Reason for Use code 316, 317 requiredMarketed · checked 2026-09-02
Write on scriptLU code 316, 317 (patient must meet the criteria below)
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Ontario Limited Use criteria — code 316, 317
Coverage limit:
Osteoarthritis
Reason for Use code 316
For patients who have failed an adequate trial of acetaminophen (e.g. acetaminophen 1g QID for several weeks) and have had:
Coverage limit:
History of a documented, clinically significant ulcer or GI bleed; or
Failure or intolerance to at least three listed NSAIDS.
Coverage limit:
The maximum daily dose of celecoxib which will be reimbursed for the treatment of osteoarthritis is 200mg.
Coverage limit:
LU Authorization Period: 1 year
Coverage limit:
Rheumatoid arthritis
Reason for Use code 317
For patients who have had:
Coverage limit:
History of a documented, clinically significant ulcer or GI bleed; or
Failure or intolerance to at least three listed NSAIDS.
Coverage limit:
The maximum daily dose of celecoxib which will be reimbursed for the treatment of rheumatoid arthritis is 400mg.
Coverage limit:
LU Authorization Period: 1 year
Brand vs generic price
Lowest DBP recovery rule under medically necessary no-substitution claims:
6.2 Medically Necessary "No Substitution" Claims
The Side Effect Reporting Form will not have to be renewed. However, the
pharmacy must maintain a copy of the prescription that contains a direction that
there be no substitution and the required Health Canada Side Effect Reporting Form
(completed and signed by the prescriber). The prescriber must write “No
Substitution” or “No Sub” on renewal or subsequent new written prescriptions, and
indicate “No Substitution” on subsequent new oral prescriptions. The dispenser will
be reimbursed the DBP plus a mark-up and the lesser of the posted usual and
customary fee or the ODB dispensing fee minus the applicable ODB co-payment
amount. Where a completed Side Effect Reporting Form is not available at the
pharmacy during an inspection, the difference between the cost of the higher-cost
product and the lowest DBP listed for the interchangeable category will be
recovered.
(ontario.ca, Revision #17; 2026-08-03 ↗)
6.2 Medically Necessary "No Substitution" Claims
The Ministry will provide reimbursement of a higher-cost interchangeable product in
medically necessary circumstances where a patient has experienced a significant
adverse reaction with two (2) lower-cost interchangeable drug products, where
available. When a prescriber identifies a patient for which it is medically necessary
that a higher cost interchangeable product be provided, the prescriber must:
• Complete, sign and forward to the pharmacist a copy of the Health Canada
side effect reporting form for each lower-cost interchangeable drug product
trialed (Side Effect Reporting Form[s]); and
• Write “No Substitution” or “No Sub” on a written prescription or indicate “No
Substitution” to the pharmacist in the case of a verbal prescription.
The prescriber should keep a copy of the completed form in the patient’s record for
future use and reference.
In the case of a written prescription, when the pharmacist or dispensing physician
receives a prescription with the written notation “No Substitution” or “No Sub”,
reimbursement will be provided for the higher-cost interchangeable product only if
the prescription is accompanied by a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed.
This form must be completely filled out noting the details of the adverse reaction
and signed by the prescriber.
In the case of a verbal prescription, the prescriber must satisfy the operator of the
pharmacy or dispensing physician that a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed
has been completed and signed by the prescriber. A written record of this verbal
prescription and the completed Health Canada Side Effect Reporting Form must be
received by the pharmacy prior to claim submission.
Upon receipt, the pharmacist must:
• Fax, submit online or mail the completed and signed form to Health Canada’s
Canada Vigilance Program; and
• Retain his or her copy of the completed and signed Side Effect Reporting
Form.
(ontario.ca, Revision #17; 2026-08-03 ↗)1 brand, same coverage
PMSC-Celecoxib · DIN 02517116
Manufacturer: Pharmascience Inc.; listing date 2022-01-31
Health Canada: Marketed since 2021-11-09 · brand PMSC-CELECOXIB · ATC M01AH01 CELECOXIB · form Capsule · route Oral · ingredients CELECOXIB 100 MG · company Pharmascience inc · schedule Prescription
Check this DIN again · Health Canada product recordPMSC-Celecoxib: Formulary list price $0.1279/unit (unit not stated in source; not the patient's cost)
Ministry pays: $0.1279 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=100645 · Verify on the e-Formulary ↗ (DIN 02517116)
Source record
DIN 02517116: PMSC-Celecoxib
Raw flags: sec12=Y, sec3=Y
Item: 280804075; group id 377; item number 0898; lccId 00064; manufacturer id PMS
Source form: Cap; strength: 100mg
Recorded listing: Limited Use: paid only with a Reason for Use code and the criteria below
Source prices (unrounded): $0.1279; ministry $0.1279
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02517116
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=100645
Therapeutic Notes (formulary)
NSAIDs have a high rate of serious adverse effects in the elderly. When prescribing NSAIDs, the minimal effective dose for the shortest period of time should be used. In nonspecific pain and/or osteoarthritis, in the absence of joint inflammation (swelling), acetaminophen is a better first choice for analgesia. The most effective treatment to prevent NSAID-gastritis is misoprostol; although H-2 antagonists, such as ranitidine or cimetidine, are commonly used, they are not as effective. NSAIDs can significantly aggravate hypertension and congestive heart failure; ASA in doses below 1 gram per day is a better choice than other NSAID options if anti-inflammatory effects are required in patients with these conditions. Low dose ASA has additional benefits for anti-platelet indications that are not provided by other NSAIDs, and should be given in preference or in addition to other NSAIDs for patients with vascular indications.
Interchangeable products
AG-Celecoxib · DIN 02437570 · $0.1279
Act Celecoxib · DIN 02420155 · $0.1279
Apo-Celecoxib · DIN 02418932 · $0.1279
Auro-Celecoxib · DIN 02445670 · $0.1279
Bio-Celecoxib · DIN 02426382 · $0.1279
Celebrex · DIN 02239941 · $0.1279
Celecoxib · DIN 02429675 · $0.1279
Celecoxib · DIN 02436299 · $0.1279
Jamp-Celecoxib · DIN 02424533 · $0.1279
M-Celecoxib · DIN 02495465 · $0.1279
Mar-Celecoxib · DIN 02420058 · $0.1279
Mint-Celecoxib · DIN 02412497 · $0.1279
NRA-Celecoxib · DIN 02479737 · $0.1279
PMS-Celecoxib · DIN 02355442 · $0.1279
Ran-Celecoxib · DIN 02412373 · $0.1279
Sdz Celecoxib · DIN 02442639 · $0.1279
Teva-Celecoxib · DIN 02288915 · $0.1279
Shortage status: resolved shortage (ended 2025-05-20); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02517116
Shortage record checked 2026-09-13T08:10:21.292534+00:00
AG-Celecoxib · DIN 02437589 · 200mg · capsule
Limited Use — Reason for Use code 316, 317 requiredMarketed · checked 2026-09-02
Write on scriptLU code 316, 317 (patient must meet the criteria below)
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Ontario Limited Use criteria — code 316, 317
Coverage limit:
Osteoarthritis
Reason for Use code 316
For patients who have failed an adequate trial of acetaminophen (e.g. acetaminophen 1g QID for several weeks) and have had:
Coverage limit:
History of a documented, clinically significant ulcer or GI bleed; or
Failure or intolerance to at least three listed NSAIDS.
Coverage limit:
The maximum daily dose of celecoxib which will be reimbursed for the treatment of osteoarthritis is 200mg.
Coverage limit:
LU Authorization Period: 1 year
Coverage limit:
Rheumatoid arthritis
Reason for Use code 317
For patients who have had:
Coverage limit:
History of a documented, clinically significant ulcer or GI bleed; or
Failure or intolerance to at least three listed NSAIDS.
Coverage limit:
The maximum daily dose of celecoxib which will be reimbursed for the treatment of rheumatoid arthritis is 400mg.
Coverage limit:
LU Authorization Period: 1 year
Brand vs generic price
Lowest DBP recovery rule under medically necessary no-substitution claims:
6.2 Medically Necessary "No Substitution" Claims
The Side Effect Reporting Form will not have to be renewed. However, the
pharmacy must maintain a copy of the prescription that contains a direction that
there be no substitution and the required Health Canada Side Effect Reporting Form
(completed and signed by the prescriber). The prescriber must write “No
Substitution” or “No Sub” on renewal or subsequent new written prescriptions, and
indicate “No Substitution” on subsequent new oral prescriptions. The dispenser will
be reimbursed the DBP plus a mark-up and the lesser of the posted usual and
customary fee or the ODB dispensing fee minus the applicable ODB co-payment
amount. Where a completed Side Effect Reporting Form is not available at the
pharmacy during an inspection, the difference between the cost of the higher-cost
product and the lowest DBP listed for the interchangeable category will be
recovered.
(ontario.ca, Revision #17; 2026-08-03 ↗)
6.2 Medically Necessary "No Substitution" Claims
The Ministry will provide reimbursement of a higher-cost interchangeable product in
medically necessary circumstances where a patient has experienced a significant
adverse reaction with two (2) lower-cost interchangeable drug products, where
available. When a prescriber identifies a patient for which it is medically necessary
that a higher cost interchangeable product be provided, the prescriber must:
• Complete, sign and forward to the pharmacist a copy of the Health Canada
side effect reporting form for each lower-cost interchangeable drug product
trialed (Side Effect Reporting Form[s]); and
• Write “No Substitution” or “No Sub” on a written prescription or indicate “No
Substitution” to the pharmacist in the case of a verbal prescription.
The prescriber should keep a copy of the completed form in the patient’s record for
future use and reference.
In the case of a written prescription, when the pharmacist or dispensing physician
receives a prescription with the written notation “No Substitution” or “No Sub”,
reimbursement will be provided for the higher-cost interchangeable product only if
the prescription is accompanied by a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed.
This form must be completely filled out noting the details of the adverse reaction
and signed by the prescriber.
In the case of a verbal prescription, the prescriber must satisfy the operator of the
pharmacy or dispensing physician that a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed
has been completed and signed by the prescriber. A written record of this verbal
prescription and the completed Health Canada Side Effect Reporting Form must be
received by the pharmacy prior to claim submission.
Upon receipt, the pharmacist must:
• Fax, submit online or mail the completed and signed form to Health Canada’s
Canada Vigilance Program; and
• Retain his or her copy of the completed and signed Side Effect Reporting
Form.
(ontario.ca, Revision #17; 2026-08-03 ↗)1 brand, same coverage
AG-Celecoxib · DIN 02437589
Manufacturer: Angita Pharma Inc.; listing date 2020-11-30
Health Canada: Marketed since 2019-05-13 · brand AG-CELECOXIB · ATC M01AH01 CELECOXIB · form Capsule · route Oral · ingredients CELECOXIB 200 MG · company Angita pharma inc. · schedule Prescription
Check this DIN again · Health Canada product recordAG-Celecoxib: Formulary list price $0.2558/unit (unit not stated in source; not the patient's cost)
Ministry pays: $0.2558 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=92191 · Verify on the e-Formulary ↗ (DIN 02437589)
Source record
DIN 02437589: AG-Celecoxib
Raw flags: sec12=Y, sec3=Y
Item: 280804076; group id 377; item number 0899; lccId 00064; manufacturer id ANG
Source form: Cap; strength: 200mg
Recorded listing: Limited Use: paid only with a Reason for Use code and the criteria below
Source prices (unrounded): $0.2558; ministry $0.2558
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02437589
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=92191
Therapeutic Notes (formulary)
NSAIDs have a high rate of serious adverse effects in the elderly. When prescribing NSAIDs, the minimal effective dose for the shortest period of time should be used. In nonspecific pain and/or osteoarthritis, in the absence of joint inflammation (swelling), acetaminophen is a better first choice for analgesia. The most effective treatment to prevent NSAID-gastritis is misoprostol; although H-2 antagonists, such as ranitidine or cimetidine, are commonly used, they are not as effective. NSAIDs can significantly aggravate hypertension and congestive heart failure; ASA in doses below 1 gram per day is a better choice than other NSAID options if anti-inflammatory effects are required in patients with these conditions. Low dose ASA has additional benefits for anti-platelet indications that are not provided by other NSAIDs, and should be given in preference or in addition to other NSAIDs for patients with vascular indications.
Interchangeable products
Act Celecoxib · DIN 02420163 · $0.2558
Apo-Celecoxib · DIN 02418940 · $0.2558
Auro-Celecoxib · DIN 02445689 · $0.2558
Bio-Celecoxib · DIN 02426390 · $0.2558
Celebrex · DIN 02239942 · $0.2558
Celecoxib · DIN 02429683 · $0.2558
Celecoxib · DIN 02436302 · $0.2558
Jamp-Celecoxib · DIN 02424541 · $0.2558
M-Celecoxib · DIN 02495473 · $0.2558
Mar-Celecoxib · DIN 02420066 · $0.2558
Mint-Celecoxib · DIN 02412500 · $0.2558
NRA-Celecoxib · DIN 02479745 · $0.2558
PMS-Celecoxib · DIN 02355450 · $0.2558
PMSC-Celecoxib · DIN 02517124 · $0.2558
Ran-Celecoxib · DIN 02412381 · $0.2558
Sdz Celecoxib · DIN 02442647 · $0.2558
Teva-Celecoxib · DIN 02288923 · $0.2558
Shortage status: no shortage or discontinuation reported (checked 2026-09-13T08:10:21.292534+00:00); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02437589
Shortage record checked 2026-09-13T08:10:21.292534+00:00
Apo-Celecoxib · DIN 02418940 · 200mg · capsule
Limited Use — Reason for Use code 316, 317 requiredMarketed · checked 2026-09-02
Write on scriptLU code 316, 317 (patient must meet the criteria below)
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Ontario Limited Use criteria — code 316, 317
Coverage limit:
Osteoarthritis
Reason for Use code 316
For patients who have failed an adequate trial of acetaminophen (e.g. acetaminophen 1g QID for several weeks) and have had:
Coverage limit:
History of a documented, clinically significant ulcer or GI bleed; or
Failure or intolerance to at least three listed NSAIDS.
Coverage limit:
The maximum daily dose of celecoxib which will be reimbursed for the treatment of osteoarthritis is 200mg.
Coverage limit:
LU Authorization Period: 1 year
Coverage limit:
Rheumatoid arthritis
Reason for Use code 317
For patients who have had:
Coverage limit:
History of a documented, clinically significant ulcer or GI bleed; or
Failure or intolerance to at least three listed NSAIDS.
Coverage limit:
The maximum daily dose of celecoxib which will be reimbursed for the treatment of rheumatoid arthritis is 400mg.
Coverage limit:
LU Authorization Period: 1 year
Brand vs generic price
Lowest DBP recovery rule under medically necessary no-substitution claims:
6.2 Medically Necessary "No Substitution" Claims
The Side Effect Reporting Form will not have to be renewed. However, the
pharmacy must maintain a copy of the prescription that contains a direction that
there be no substitution and the required Health Canada Side Effect Reporting Form
(completed and signed by the prescriber). The prescriber must write “No
Substitution” or “No Sub” on renewal or subsequent new written prescriptions, and
indicate “No Substitution” on subsequent new oral prescriptions. The dispenser will
be reimbursed the DBP plus a mark-up and the lesser of the posted usual and
customary fee or the ODB dispensing fee minus the applicable ODB co-payment
amount. Where a completed Side Effect Reporting Form is not available at the
pharmacy during an inspection, the difference between the cost of the higher-cost
product and the lowest DBP listed for the interchangeable category will be
recovered.
(ontario.ca, Revision #17; 2026-08-03 ↗)
6.2 Medically Necessary "No Substitution" Claims
The Ministry will provide reimbursement of a higher-cost interchangeable product in
medically necessary circumstances where a patient has experienced a significant
adverse reaction with two (2) lower-cost interchangeable drug products, where
available. When a prescriber identifies a patient for which it is medically necessary
that a higher cost interchangeable product be provided, the prescriber must:
• Complete, sign and forward to the pharmacist a copy of the Health Canada
side effect reporting form for each lower-cost interchangeable drug product
trialed (Side Effect Reporting Form[s]); and
• Write “No Substitution” or “No Sub” on a written prescription or indicate “No
Substitution” to the pharmacist in the case of a verbal prescription.
The prescriber should keep a copy of the completed form in the patient’s record for
future use and reference.
In the case of a written prescription, when the pharmacist or dispensing physician
receives a prescription with the written notation “No Substitution” or “No Sub”,
reimbursement will be provided for the higher-cost interchangeable product only if
the prescription is accompanied by a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed.
This form must be completely filled out noting the details of the adverse reaction
and signed by the prescriber.
In the case of a verbal prescription, the prescriber must satisfy the operator of the
pharmacy or dispensing physician that a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed
has been completed and signed by the prescriber. A written record of this verbal
prescription and the completed Health Canada Side Effect Reporting Form must be
received by the pharmacy prior to claim submission.
Upon receipt, the pharmacist must:
• Fax, submit online or mail the completed and signed form to Health Canada’s
Canada Vigilance Program; and
• Retain his or her copy of the completed and signed Side Effect Reporting
Form.
(ontario.ca, Revision #17; 2026-08-03 ↗)1 brand, same coverage
Apo-Celecoxib · DIN 02418940
Manufacturer: Apotex Inc.; listing date 2015-01-28
Health Canada: Marketed since 2014-11-17 · brand APO-CELECOXIB · ATC M01AH01 CELECOXIB · form Capsule · route Oral · ingredients CELECOXIB 200 MG · company Apotex inc · schedule Prescription
Check this DIN again · Health Canada product recordApo-Celecoxib: Formulary list price $0.2558/unit (unit not stated in source; not the patient's cost)
Ministry pays: $0.2558 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=90348 · Verify on the e-Formulary ↗ (DIN 02418940)
Source record
DIN 02418940: Apo-Celecoxib
Raw flags: sec12=Y, sec3=Y
Item: 280804076; group id 377; item number 0899; lccId 00064; manufacturer id APX
Source form: Cap; strength: 200mg
Recorded listing: Limited Use: paid only with a Reason for Use code and the criteria below
Source prices (unrounded): $0.2558; ministry $0.2558
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02418940
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=90348
Therapeutic Notes (formulary)
NSAIDs have a high rate of serious adverse effects in the elderly. When prescribing NSAIDs, the minimal effective dose for the shortest period of time should be used. In nonspecific pain and/or osteoarthritis, in the absence of joint inflammation (swelling), acetaminophen is a better first choice for analgesia. The most effective treatment to prevent NSAID-gastritis is misoprostol; although H-2 antagonists, such as ranitidine or cimetidine, are commonly used, they are not as effective. NSAIDs can significantly aggravate hypertension and congestive heart failure; ASA in doses below 1 gram per day is a better choice than other NSAID options if anti-inflammatory effects are required in patients with these conditions. Low dose ASA has additional benefits for anti-platelet indications that are not provided by other NSAIDs, and should be given in preference or in addition to other NSAIDs for patients with vascular indications.
Interchangeable products
AG-Celecoxib · DIN 02437589 · $0.2558
Act Celecoxib · DIN 02420163 · $0.2558
Auro-Celecoxib · DIN 02445689 · $0.2558
Bio-Celecoxib · DIN 02426390 · $0.2558
Celebrex · DIN 02239942 · $0.2558
Celecoxib · DIN 02429683 · $0.2558
Celecoxib · DIN 02436302 · $0.2558
Jamp-Celecoxib · DIN 02424541 · $0.2558
M-Celecoxib · DIN 02495473 · $0.2558
Mar-Celecoxib · DIN 02420066 · $0.2558
Mint-Celecoxib · DIN 02412500 · $0.2558
NRA-Celecoxib · DIN 02479745 · $0.2558
PMS-Celecoxib · DIN 02355450 · $0.2558
PMSC-Celecoxib · DIN 02517124 · $0.2558
Ran-Celecoxib · DIN 02412381 · $0.2558
Sdz Celecoxib · DIN 02442647 · $0.2558
Teva-Celecoxib · DIN 02288923 · $0.2558
Shortage status: resolved shortage (ended 2024-12-12); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02418940
Shortage record checked 2026-09-13T08:10:21.292534+00:00
Auro-Celecoxib · DIN 02445689 · 200mg · capsule
Limited Use — Reason for Use code 316, 317 requiredMarketed · checked 2026-09-02
Write on scriptLU code 316, 317 (patient must meet the criteria below)
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Ontario Limited Use criteria — code 316, 317
Coverage limit:
Osteoarthritis
Reason for Use code 316
For patients who have failed an adequate trial of acetaminophen (e.g. acetaminophen 1g QID for several weeks) and have had:
Coverage limit:
History of a documented, clinically significant ulcer or GI bleed; or
Failure or intolerance to at least three listed NSAIDS.
Coverage limit:
The maximum daily dose of celecoxib which will be reimbursed for the treatment of osteoarthritis is 200mg.
Coverage limit:
LU Authorization Period: 1 year
Coverage limit:
Rheumatoid arthritis
Reason for Use code 317
For patients who have had:
Coverage limit:
History of a documented, clinically significant ulcer or GI bleed; or
Failure or intolerance to at least three listed NSAIDS.
Coverage limit:
The maximum daily dose of celecoxib which will be reimbursed for the treatment of rheumatoid arthritis is 400mg.
Coverage limit:
LU Authorization Period: 1 year
Brand vs generic price
Lowest DBP recovery rule under medically necessary no-substitution claims:
6.2 Medically Necessary "No Substitution" Claims
The Side Effect Reporting Form will not have to be renewed. However, the
pharmacy must maintain a copy of the prescription that contains a direction that
there be no substitution and the required Health Canada Side Effect Reporting Form
(completed and signed by the prescriber). The prescriber must write “No
Substitution” or “No Sub” on renewal or subsequent new written prescriptions, and
indicate “No Substitution” on subsequent new oral prescriptions. The dispenser will
be reimbursed the DBP plus a mark-up and the lesser of the posted usual and
customary fee or the ODB dispensing fee minus the applicable ODB co-payment
amount. Where a completed Side Effect Reporting Form is not available at the
pharmacy during an inspection, the difference between the cost of the higher-cost
product and the lowest DBP listed for the interchangeable category will be
recovered.
(ontario.ca, Revision #17; 2026-08-03 ↗)
6.2 Medically Necessary "No Substitution" Claims
The Ministry will provide reimbursement of a higher-cost interchangeable product in
medically necessary circumstances where a patient has experienced a significant
adverse reaction with two (2) lower-cost interchangeable drug products, where
available. When a prescriber identifies a patient for which it is medically necessary
that a higher cost interchangeable product be provided, the prescriber must:
• Complete, sign and forward to the pharmacist a copy of the Health Canada
side effect reporting form for each lower-cost interchangeable drug product
trialed (Side Effect Reporting Form[s]); and
• Write “No Substitution” or “No Sub” on a written prescription or indicate “No
Substitution” to the pharmacist in the case of a verbal prescription.
The prescriber should keep a copy of the completed form in the patient’s record for
future use and reference.
In the case of a written prescription, when the pharmacist or dispensing physician
receives a prescription with the written notation “No Substitution” or “No Sub”,
reimbursement will be provided for the higher-cost interchangeable product only if
the prescription is accompanied by a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed.
This form must be completely filled out noting the details of the adverse reaction
and signed by the prescriber.
In the case of a verbal prescription, the prescriber must satisfy the operator of the
pharmacy or dispensing physician that a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed
has been completed and signed by the prescriber. A written record of this verbal
prescription and the completed Health Canada Side Effect Reporting Form must be
received by the pharmacy prior to claim submission.
Upon receipt, the pharmacist must:
• Fax, submit online or mail the completed and signed form to Health Canada’s
Canada Vigilance Program; and
• Retain his or her copy of the completed and signed Side Effect Reporting
Form.
(ontario.ca, Revision #17; 2026-08-03 ↗)1 brand, same coverage
Auro-Celecoxib · DIN 02445689
Manufacturer: Auro Pharma Inc.; listing date 2016-07-28
Health Canada: Marketed since 2015-12-02 · brand AURO-CELECOXIB · ATC M01AH01 CELECOXIB · form Capsule · route Oral · ingredients CELECOXIB 200 MG · company Auro pharma inc · schedule Prescription
Check this DIN again · Health Canada product recordAuro-Celecoxib: Formulary list price $0.2558/unit (unit not stated in source; not the patient's cost)
Ministry pays: $0.2558 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=93096 · Verify on the e-Formulary ↗ (DIN 02445689)
Source record
DIN 02445689: Auro-Celecoxib
Raw flags: sec12=Y, sec3=Y
Item: 280804076; group id 377; item number 0899; lccId 00064; manufacturer id AUR
Source form: Cap; strength: 200mg
Recorded listing: Limited Use: paid only with a Reason for Use code and the criteria below
Source prices (unrounded): $0.2558; ministry $0.2558
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02445689
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=93096
Therapeutic Notes (formulary)
NSAIDs have a high rate of serious adverse effects in the elderly. When prescribing NSAIDs, the minimal effective dose for the shortest period of time should be used. In nonspecific pain and/or osteoarthritis, in the absence of joint inflammation (swelling), acetaminophen is a better first choice for analgesia. The most effective treatment to prevent NSAID-gastritis is misoprostol; although H-2 antagonists, such as ranitidine or cimetidine, are commonly used, they are not as effective. NSAIDs can significantly aggravate hypertension and congestive heart failure; ASA in doses below 1 gram per day is a better choice than other NSAID options if anti-inflammatory effects are required in patients with these conditions. Low dose ASA has additional benefits for anti-platelet indications that are not provided by other NSAIDs, and should be given in preference or in addition to other NSAIDs for patients with vascular indications.
Interchangeable products
AG-Celecoxib · DIN 02437589 · $0.2558
Act Celecoxib · DIN 02420163 · $0.2558
Apo-Celecoxib · DIN 02418940 · $0.2558
Bio-Celecoxib · DIN 02426390 · $0.2558
Celebrex · DIN 02239942 · $0.2558
Celecoxib · DIN 02429683 · $0.2558
Celecoxib · DIN 02436302 · $0.2558
Jamp-Celecoxib · DIN 02424541 · $0.2558
M-Celecoxib · DIN 02495473 · $0.2558
Mar-Celecoxib · DIN 02420066 · $0.2558
Mint-Celecoxib · DIN 02412500 · $0.2558
NRA-Celecoxib · DIN 02479745 · $0.2558
PMS-Celecoxib · DIN 02355450 · $0.2558
PMSC-Celecoxib · DIN 02517124 · $0.2558
Ran-Celecoxib · DIN 02412381 · $0.2558
Sdz Celecoxib · DIN 02442647 · $0.2558
Teva-Celecoxib · DIN 02288923 · $0.2558
Shortage status: resolved shortage (ended 2024-06-28); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02445689
Shortage record checked 2026-09-13T08:10:21.292534+00:00
Bio-Celecoxib · DIN 02426390 · 200mg · capsule
Limited Use — Reason for Use code 316, 317 requiredMarketed · checked 2026-09-02
Write on scriptLU code 316, 317 (patient must meet the criteria below)
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Ontario Limited Use criteria — code 316, 317
Coverage limit:
Osteoarthritis
Reason for Use code 316
For patients who have failed an adequate trial of acetaminophen (e.g. acetaminophen 1g QID for several weeks) and have had:
Coverage limit:
History of a documented, clinically significant ulcer or GI bleed; or
Failure or intolerance to at least three listed NSAIDS.
Coverage limit:
The maximum daily dose of celecoxib which will be reimbursed for the treatment of osteoarthritis is 200mg.
Coverage limit:
LU Authorization Period: 1 year
Coverage limit:
Rheumatoid arthritis
Reason for Use code 317
For patients who have had:
Coverage limit:
History of a documented, clinically significant ulcer or GI bleed; or
Failure or intolerance to at least three listed NSAIDS.
Coverage limit:
The maximum daily dose of celecoxib which will be reimbursed for the treatment of rheumatoid arthritis is 400mg.
Coverage limit:
LU Authorization Period: 1 year
Brand vs generic price
Lowest DBP recovery rule under medically necessary no-substitution claims:
6.2 Medically Necessary "No Substitution" Claims
The Side Effect Reporting Form will not have to be renewed. However, the
pharmacy must maintain a copy of the prescription that contains a direction that
there be no substitution and the required Health Canada Side Effect Reporting Form
(completed and signed by the prescriber). The prescriber must write “No
Substitution” or “No Sub” on renewal or subsequent new written prescriptions, and
indicate “No Substitution” on subsequent new oral prescriptions. The dispenser will
be reimbursed the DBP plus a mark-up and the lesser of the posted usual and
customary fee or the ODB dispensing fee minus the applicable ODB co-payment
amount. Where a completed Side Effect Reporting Form is not available at the
pharmacy during an inspection, the difference between the cost of the higher-cost
product and the lowest DBP listed for the interchangeable category will be
recovered.
(ontario.ca, Revision #17; 2026-08-03 ↗)
6.2 Medically Necessary "No Substitution" Claims
The Ministry will provide reimbursement of a higher-cost interchangeable product in
medically necessary circumstances where a patient has experienced a significant
adverse reaction with two (2) lower-cost interchangeable drug products, where
available. When a prescriber identifies a patient for which it is medically necessary
that a higher cost interchangeable product be provided, the prescriber must:
• Complete, sign and forward to the pharmacist a copy of the Health Canada
side effect reporting form for each lower-cost interchangeable drug product
trialed (Side Effect Reporting Form[s]); and
• Write “No Substitution” or “No Sub” on a written prescription or indicate “No
Substitution” to the pharmacist in the case of a verbal prescription.
The prescriber should keep a copy of the completed form in the patient’s record for
future use and reference.
In the case of a written prescription, when the pharmacist or dispensing physician
receives a prescription with the written notation “No Substitution” or “No Sub”,
reimbursement will be provided for the higher-cost interchangeable product only if
the prescription is accompanied by a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed.
This form must be completely filled out noting the details of the adverse reaction
and signed by the prescriber.
In the case of a verbal prescription, the prescriber must satisfy the operator of the
pharmacy or dispensing physician that a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed
has been completed and signed by the prescriber. A written record of this verbal
prescription and the completed Health Canada Side Effect Reporting Form must be
received by the pharmacy prior to claim submission.
Upon receipt, the pharmacist must:
• Fax, submit online or mail the completed and signed form to Health Canada’s
Canada Vigilance Program; and
• Retain his or her copy of the completed and signed Side Effect Reporting
Form.
(ontario.ca, Revision #17; 2026-08-03 ↗)1 brand, same coverage
Bio-Celecoxib · DIN 02426390
Manufacturer: Biomed Pharma; listing date 2016-02-25
Health Canada: Marketed since 2014-12-05 · brand BIO-CELECOXIB · ATC M01AH01 CELECOXIB · form Capsule · route Oral · ingredients CELECOXIB 200 MG · company Biomed pharma · schedule Prescription
Check this DIN again · Health Canada product recordBio-Celecoxib: Formulary list price $0.2558/unit (unit not stated in source; not the patient's cost)
Ministry pays: $0.2558 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=91098 · Verify on the e-Formulary ↗ (DIN 02426390)
Source record
DIN 02426390: Bio-Celecoxib
Raw flags: sec12=Y, sec3=Y
Item: 280804076; group id 377; item number 0899; lccId 00064; manufacturer id BMP
Source form: Cap; strength: 200mg
Recorded listing: Limited Use: paid only with a Reason for Use code and the criteria below
Source prices (unrounded): $0.2558; ministry $0.2558
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02426390
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=91098
Therapeutic Notes (formulary)
NSAIDs have a high rate of serious adverse effects in the elderly. When prescribing NSAIDs, the minimal effective dose for the shortest period of time should be used. In nonspecific pain and/or osteoarthritis, in the absence of joint inflammation (swelling), acetaminophen is a better first choice for analgesia. The most effective treatment to prevent NSAID-gastritis is misoprostol; although H-2 antagonists, such as ranitidine or cimetidine, are commonly used, they are not as effective. NSAIDs can significantly aggravate hypertension and congestive heart failure; ASA in doses below 1 gram per day is a better choice than other NSAID options if anti-inflammatory effects are required in patients with these conditions. Low dose ASA has additional benefits for anti-platelet indications that are not provided by other NSAIDs, and should be given in preference or in addition to other NSAIDs for patients with vascular indications.
Interchangeable products
AG-Celecoxib · DIN 02437589 · $0.2558
Act Celecoxib · DIN 02420163 · $0.2558
Apo-Celecoxib · DIN 02418940 · $0.2558
Auro-Celecoxib · DIN 02445689 · $0.2558
Celebrex · DIN 02239942 · $0.2558
Celecoxib · DIN 02429683 · $0.2558
Celecoxib · DIN 02436302 · $0.2558
Jamp-Celecoxib · DIN 02424541 · $0.2558
M-Celecoxib · DIN 02495473 · $0.2558
Mar-Celecoxib · DIN 02420066 · $0.2558
Mint-Celecoxib · DIN 02412500 · $0.2558
NRA-Celecoxib · DIN 02479745 · $0.2558
PMS-Celecoxib · DIN 02355450 · $0.2558
PMSC-Celecoxib · DIN 02517124 · $0.2558
Ran-Celecoxib · DIN 02412381 · $0.2558
Sdz Celecoxib · DIN 02442647 · $0.2558
Teva-Celecoxib · DIN 02288923 · $0.2558
Shortage status: resolved shortage (ended 2019-07-20); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02426390
Shortage record checked 2026-09-13T08:10:21.292534+00:00
Celebrex · DIN 02239942 · 200mg · capsule
Limited Use — Reason for Use code 316, 317 requiredMarketed · checked 2026-09-02
Write on scriptLU code 316, 317 (patient must meet the criteria below)
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Ontario Limited Use criteria — code 316, 317
Coverage limit:
Osteoarthritis
Reason for Use code 316
For patients who have failed an adequate trial of acetaminophen (e.g. acetaminophen 1g QID for several weeks) and have had:
Coverage limit:
History of a documented, clinically significant ulcer or GI bleed; or
Failure or intolerance to at least three listed NSAIDS.
Coverage limit:
The maximum daily dose of celecoxib which will be reimbursed for the treatment of osteoarthritis is 200mg.
Coverage limit:
LU Authorization Period: 1 year
Coverage limit:
Rheumatoid arthritis
Reason for Use code 317
For patients who have had:
Coverage limit:
History of a documented, clinically significant ulcer or GI bleed; or
Failure or intolerance to at least three listed NSAIDS.
Coverage limit:
The maximum daily dose of celecoxib which will be reimbursed for the treatment of rheumatoid arthritis is 400mg.
Coverage limit:
LU Authorization Period: 1 year
Savings card: RxHelp ONE lists Celebrex (read 2026-09-10) — brand-name savings card, free; cannot be combined with another card on the same claim.
(rxhelp.ca ↗)1 brand, same coverage
Celebrex · DIN 02239942
Manufacturer: Upjohn Canada ULC; listing date 2000-04-17
Health Canada: Marketed since 2023-09-26 · brand CELEBREX · ATC M01AH01 CELECOXIB · form Capsule · route Oral · ingredients CELECOXIB 200 MG · company Bgp pharma ulc · schedule Prescription
Check this DIN again · Health Canada product recordMinistry pays: $0.2558 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=63443 · Verify on the e-Formulary ↗ (DIN 02239942)
Source record
DIN 02239942: Celebrex
Raw flags: sec12=Y, sec3=Y
Item: 280804076; group id 377; item number 0899; lccId 00064; manufacturer id UJC
Source form: Cap; strength: 200mg
Recorded listing: Limited Use: paid only with a Reason for Use code and the criteria below
Source prices (unrounded): $1.6966; ministry $0.2558
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02239942
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=63443
Therapeutic Notes (formulary)
NSAIDs have a high rate of serious adverse effects in the elderly. When prescribing NSAIDs, the minimal effective dose for the shortest period of time should be used. In nonspecific pain and/or osteoarthritis, in the absence of joint inflammation (swelling), acetaminophen is a better first choice for analgesia. The most effective treatment to prevent NSAID-gastritis is misoprostol; although H-2 antagonists, such as ranitidine or cimetidine, are commonly used, they are not as effective. NSAIDs can significantly aggravate hypertension and congestive heart failure; ASA in doses below 1 gram per day is a better choice than other NSAID options if anti-inflammatory effects are required in patients with these conditions. Low dose ASA has additional benefits for anti-platelet indications that are not provided by other NSAIDs, and should be given in preference or in addition to other NSAIDs for patients with vascular indications.
Interchangeable products
AG-Celecoxib · DIN 02437589 · $0.2558
Act Celecoxib · DIN 02420163 · $0.2558
Apo-Celecoxib · DIN 02418940 · $0.2558
Auro-Celecoxib · DIN 02445689 · $0.2558
Bio-Celecoxib · DIN 02426390 · $0.2558
Celecoxib · DIN 02429683 · $0.2558
Celecoxib · DIN 02436302 · $0.2558
Jamp-Celecoxib · DIN 02424541 · $0.2558
M-Celecoxib · DIN 02495473 · $0.2558
Mar-Celecoxib · DIN 02420066 · $0.2558
Mint-Celecoxib · DIN 02412500 · $0.2558
NRA-Celecoxib · DIN 02479745 · $0.2558
PMS-Celecoxib · DIN 02355450 · $0.2558
PMSC-Celecoxib · DIN 02517124 · $0.2558
Ran-Celecoxib · DIN 02412381 · $0.2558
Sdz Celecoxib · DIN 02442647 · $0.2558
Teva-Celecoxib · DIN 02288923 · $0.2558
Shortage status: resolved shortage (ended 2022-06-03); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02239942
Shortage record checked 2026-09-13T08:10:21.292534+00:00
Celecoxib · DIN 02429683 · 200mg · capsule
Limited Use — Reason for Use code 316, 317 requiredMarketed · checked 2026-09-02
Write on scriptLU code 316, 317 (patient must meet the criteria below)
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Ontario Limited Use criteria — code 316, 317
Coverage limit:
Osteoarthritis
Reason for Use code 316
For patients who have failed an adequate trial of acetaminophen (e.g. acetaminophen 1g QID for several weeks) and have had:
Coverage limit:
History of a documented, clinically significant ulcer or GI bleed; or
Failure or intolerance to at least three listed NSAIDS.
Coverage limit:
The maximum daily dose of celecoxib which will be reimbursed for the treatment of osteoarthritis is 200mg.
Coverage limit:
LU Authorization Period: 1 year
Coverage limit:
Rheumatoid arthritis
Reason for Use code 317
For patients who have had:
Coverage limit:
History of a documented, clinically significant ulcer or GI bleed; or
Failure or intolerance to at least three listed NSAIDS.
Coverage limit:
The maximum daily dose of celecoxib which will be reimbursed for the treatment of rheumatoid arthritis is 400mg.
Coverage limit:
LU Authorization Period: 1 year
Brand vs generic price
Lowest DBP recovery rule under medically necessary no-substitution claims:
6.2 Medically Necessary "No Substitution" Claims
The Side Effect Reporting Form will not have to be renewed. However, the
pharmacy must maintain a copy of the prescription that contains a direction that
there be no substitution and the required Health Canada Side Effect Reporting Form
(completed and signed by the prescriber). The prescriber must write “No
Substitution” or “No Sub” on renewal or subsequent new written prescriptions, and
indicate “No Substitution” on subsequent new oral prescriptions. The dispenser will
be reimbursed the DBP plus a mark-up and the lesser of the posted usual and
customary fee or the ODB dispensing fee minus the applicable ODB co-payment
amount. Where a completed Side Effect Reporting Form is not available at the
pharmacy during an inspection, the difference between the cost of the higher-cost
product and the lowest DBP listed for the interchangeable category will be
recovered.
(ontario.ca, Revision #17; 2026-08-03 ↗)
6.2 Medically Necessary "No Substitution" Claims
The Ministry will provide reimbursement of a higher-cost interchangeable product in
medically necessary circumstances where a patient has experienced a significant
adverse reaction with two (2) lower-cost interchangeable drug products, where
available. When a prescriber identifies a patient for which it is medically necessary
that a higher cost interchangeable product be provided, the prescriber must:
• Complete, sign and forward to the pharmacist a copy of the Health Canada
side effect reporting form for each lower-cost interchangeable drug product
trialed (Side Effect Reporting Form[s]); and
• Write “No Substitution” or “No Sub” on a written prescription or indicate “No
Substitution” to the pharmacist in the case of a verbal prescription.
The prescriber should keep a copy of the completed form in the patient’s record for
future use and reference.
In the case of a written prescription, when the pharmacist or dispensing physician
receives a prescription with the written notation “No Substitution” or “No Sub”,
reimbursement will be provided for the higher-cost interchangeable product only if
the prescription is accompanied by a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed.
This form must be completely filled out noting the details of the adverse reaction
and signed by the prescriber.
In the case of a verbal prescription, the prescriber must satisfy the operator of the
pharmacy or dispensing physician that a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed
has been completed and signed by the prescriber. A written record of this verbal
prescription and the completed Health Canada Side Effect Reporting Form must be
received by the pharmacy prior to claim submission.
Upon receipt, the pharmacist must:
• Fax, submit online or mail the completed and signed form to Health Canada’s
Canada Vigilance Program; and
• Retain his or her copy of the completed and signed Side Effect Reporting
Form.
(ontario.ca, Revision #17; 2026-08-03 ↗)1 brand, same coverage
Celecoxib · DIN 02429683
Manufacturer: Sivem Pharmaceuticals ULC; listing date 2020-06-30
Health Canada: Marketed since 2018-07-04 · brand CELECOXIB · ATC M01AH01 CELECOXIB · form Capsule · route Oral · ingredients CELECOXIB 200 MG · company Sivem pharmaceuticals ulc · schedule Prescription
Check this DIN again · Health Canada product recordCelecoxib: Formulary list price $0.2558/unit (unit not stated in source; not the patient's cost)
Ministry pays: $0.2558 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=91413 · Verify on the e-Formulary ↗ (DIN 02429683)
Source record
DIN 02429683: Celecoxib
Raw flags: sec12=Y, sec3=Y
Item: 280804076; group id 377; item number 0899; lccId 00064; manufacturer id SIV
Source form: Cap; strength: 200mg
Recorded listing: Limited Use: paid only with a Reason for Use code and the criteria below
Source prices (unrounded): $0.2558; ministry $0.2558
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02429683
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=91413
Therapeutic Notes (formulary)
NSAIDs have a high rate of serious adverse effects in the elderly. When prescribing NSAIDs, the minimal effective dose for the shortest period of time should be used. In nonspecific pain and/or osteoarthritis, in the absence of joint inflammation (swelling), acetaminophen is a better first choice for analgesia. The most effective treatment to prevent NSAID-gastritis is misoprostol; although H-2 antagonists, such as ranitidine or cimetidine, are commonly used, they are not as effective. NSAIDs can significantly aggravate hypertension and congestive heart failure; ASA in doses below 1 gram per day is a better choice than other NSAID options if anti-inflammatory effects are required in patients with these conditions. Low dose ASA has additional benefits for anti-platelet indications that are not provided by other NSAIDs, and should be given in preference or in addition to other NSAIDs for patients with vascular indications.
Interchangeable products
AG-Celecoxib · DIN 02437589 · $0.2558
Act Celecoxib · DIN 02420163 · $0.2558
Apo-Celecoxib · DIN 02418940 · $0.2558
Auro-Celecoxib · DIN 02445689 · $0.2558
Bio-Celecoxib · DIN 02426390 · $0.2558
Celebrex · DIN 02239942 · $0.2558
Celecoxib · DIN 02436302 · $0.2558
Jamp-Celecoxib · DIN 02424541 · $0.2558
M-Celecoxib · DIN 02495473 · $0.2558
Mar-Celecoxib · DIN 02420066 · $0.2558
Mint-Celecoxib · DIN 02412500 · $0.2558
NRA-Celecoxib · DIN 02479745 · $0.2558
PMS-Celecoxib · DIN 02355450 · $0.2558
PMSC-Celecoxib · DIN 02517124 · $0.2558
Ran-Celecoxib · DIN 02412381 · $0.2558
Sdz Celecoxib · DIN 02442647 · $0.2558
Teva-Celecoxib · DIN 02288923 · $0.2558
Shortage status: resolved shortage (ended 2020-08-10); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02429683
Shortage record checked 2026-09-13T08:10:21.292534+00:00
Celecoxib · DIN 02436302 · 200mg · capsule
Limited Use — Reason for Use code 316, 317 requiredMarketed · checked 2026-09-02
Write on scriptLU code 316, 317 (patient must meet the criteria below)
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Ontario Limited Use criteria — code 316, 317
Coverage limit:
Osteoarthritis
Reason for Use code 316
For patients who have failed an adequate trial of acetaminophen (e.g. acetaminophen 1g QID for several weeks) and have had:
Coverage limit:
History of a documented, clinically significant ulcer or GI bleed; or
Failure or intolerance to at least three listed NSAIDS.
Coverage limit:
The maximum daily dose of celecoxib which will be reimbursed for the treatment of osteoarthritis is 200mg.
Coverage limit:
LU Authorization Period: 1 year
Coverage limit:
Rheumatoid arthritis
Reason for Use code 317
For patients who have had:
Coverage limit:
History of a documented, clinically significant ulcer or GI bleed; or
Failure or intolerance to at least three listed NSAIDS.
Coverage limit:
The maximum daily dose of celecoxib which will be reimbursed for the treatment of rheumatoid arthritis is 400mg.
Coverage limit:
LU Authorization Period: 1 year
Brand vs generic price
Lowest DBP recovery rule under medically necessary no-substitution claims:
6.2 Medically Necessary "No Substitution" Claims
The Side Effect Reporting Form will not have to be renewed. However, the
pharmacy must maintain a copy of the prescription that contains a direction that
there be no substitution and the required Health Canada Side Effect Reporting Form
(completed and signed by the prescriber). The prescriber must write “No
Substitution” or “No Sub” on renewal or subsequent new written prescriptions, and
indicate “No Substitution” on subsequent new oral prescriptions. The dispenser will
be reimbursed the DBP plus a mark-up and the lesser of the posted usual and
customary fee or the ODB dispensing fee minus the applicable ODB co-payment
amount. Where a completed Side Effect Reporting Form is not available at the
pharmacy during an inspection, the difference between the cost of the higher-cost
product and the lowest DBP listed for the interchangeable category will be
recovered.
(ontario.ca, Revision #17; 2026-08-03 ↗)
6.2 Medically Necessary "No Substitution" Claims
The Ministry will provide reimbursement of a higher-cost interchangeable product in
medically necessary circumstances where a patient has experienced a significant
adverse reaction with two (2) lower-cost interchangeable drug products, where
available. When a prescriber identifies a patient for which it is medically necessary
that a higher cost interchangeable product be provided, the prescriber must:
• Complete, sign and forward to the pharmacist a copy of the Health Canada
side effect reporting form for each lower-cost interchangeable drug product
trialed (Side Effect Reporting Form[s]); and
• Write “No Substitution” or “No Sub” on a written prescription or indicate “No
Substitution” to the pharmacist in the case of a verbal prescription.
The prescriber should keep a copy of the completed form in the patient’s record for
future use and reference.
In the case of a written prescription, when the pharmacist or dispensing physician
receives a prescription with the written notation “No Substitution” or “No Sub”,
reimbursement will be provided for the higher-cost interchangeable product only if
the prescription is accompanied by a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed.
This form must be completely filled out noting the details of the adverse reaction
and signed by the prescriber.
In the case of a verbal prescription, the prescriber must satisfy the operator of the
pharmacy or dispensing physician that a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed
has been completed and signed by the prescriber. A written record of this verbal
prescription and the completed Health Canada Side Effect Reporting Form must be
received by the pharmacy prior to claim submission.
Upon receipt, the pharmacist must:
• Fax, submit online or mail the completed and signed form to Health Canada’s
Canada Vigilance Program; and
• Retain his or her copy of the completed and signed Side Effect Reporting
Form.
(ontario.ca, Revision #17; 2026-08-03 ↗)1 brand, same coverage
Celecoxib · DIN 02436302
Manufacturer: Sanis Health Inc.; listing date 2021-03-29
Health Canada: Marketed since 2021-02-02 · brand CELECOXIB · ATC M01AH01 CELECOXIB · form Capsule · route Oral · ingredients CELECOXIB 200 MG · company Sanis health inc · schedule Prescription
Check this DIN again · Health Canada product recordCelecoxib: Formulary list price $0.2558/unit (unit not stated in source; not the patient's cost)
Ministry pays: $0.2558 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=92063 · Verify on the e-Formulary ↗ (DIN 02436302)
Source record
DIN 02436302: Celecoxib
Raw flags: sec12=Y, sec3=Y
Item: 280804076; group id 377; item number 0899; lccId 00064; manufacturer id SAI
Source form: Cap; strength: 200mg
Recorded listing: Limited Use: paid only with a Reason for Use code and the criteria below
Source prices (unrounded): $0.2558; ministry $0.2558
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02436302
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=92063
Therapeutic Notes (formulary)
NSAIDs have a high rate of serious adverse effects in the elderly. When prescribing NSAIDs, the minimal effective dose for the shortest period of time should be used. In nonspecific pain and/or osteoarthritis, in the absence of joint inflammation (swelling), acetaminophen is a better first choice for analgesia. The most effective treatment to prevent NSAID-gastritis is misoprostol; although H-2 antagonists, such as ranitidine or cimetidine, are commonly used, they are not as effective. NSAIDs can significantly aggravate hypertension and congestive heart failure; ASA in doses below 1 gram per day is a better choice than other NSAID options if anti-inflammatory effects are required in patients with these conditions. Low dose ASA has additional benefits for anti-platelet indications that are not provided by other NSAIDs, and should be given in preference or in addition to other NSAIDs for patients with vascular indications.
Interchangeable products
AG-Celecoxib · DIN 02437589 · $0.2558
Act Celecoxib · DIN 02420163 · $0.2558
Apo-Celecoxib · DIN 02418940 · $0.2558
Auro-Celecoxib · DIN 02445689 · $0.2558
Bio-Celecoxib · DIN 02426390 · $0.2558
Celebrex · DIN 02239942 · $0.2558
Celecoxib · DIN 02429683 · $0.2558
Jamp-Celecoxib · DIN 02424541 · $0.2558
M-Celecoxib · DIN 02495473 · $0.2558
Mar-Celecoxib · DIN 02420066 · $0.2558
Mint-Celecoxib · DIN 02412500 · $0.2558
NRA-Celecoxib · DIN 02479745 · $0.2558
PMS-Celecoxib · DIN 02355450 · $0.2558
PMSC-Celecoxib · DIN 02517124 · $0.2558
Ran-Celecoxib · DIN 02412381 · $0.2558
Sdz Celecoxib · DIN 02442647 · $0.2558
Teva-Celecoxib · DIN 02288923 · $0.2558
Shortage status: resolved shortage (ended 2021-05-05); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02436302
Shortage record checked 2026-09-13T08:10:21.292534+00:00
Jamp-Celecoxib · DIN 02424541 · 200mg · capsule
Limited Use — Reason for Use code 316, 317 requiredMarketed · checked 2026-09-02
Write on scriptLU code 316, 317 (patient must meet the criteria below)
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Ontario Limited Use criteria — code 316, 317
Coverage limit:
Osteoarthritis
Reason for Use code 316
For patients who have failed an adequate trial of acetaminophen (e.g. acetaminophen 1g QID for several weeks) and have had:
Coverage limit:
History of a documented, clinically significant ulcer or GI bleed; or
Failure or intolerance to at least three listed NSAIDS.
Coverage limit:
The maximum daily dose of celecoxib which will be reimbursed for the treatment of osteoarthritis is 200mg.
Coverage limit:
LU Authorization Period: 1 year
Coverage limit:
Rheumatoid arthritis
Reason for Use code 317
For patients who have had:
Coverage limit:
History of a documented, clinically significant ulcer or GI bleed; or
Failure or intolerance to at least three listed NSAIDS.
Coverage limit:
The maximum daily dose of celecoxib which will be reimbursed for the treatment of rheumatoid arthritis is 400mg.
Coverage limit:
LU Authorization Period: 1 year
Brand vs generic price
Lowest DBP recovery rule under medically necessary no-substitution claims:
6.2 Medically Necessary "No Substitution" Claims
The Side Effect Reporting Form will not have to be renewed. However, the
pharmacy must maintain a copy of the prescription that contains a direction that
there be no substitution and the required Health Canada Side Effect Reporting Form
(completed and signed by the prescriber). The prescriber must write “No
Substitution” or “No Sub” on renewal or subsequent new written prescriptions, and
indicate “No Substitution” on subsequent new oral prescriptions. The dispenser will
be reimbursed the DBP plus a mark-up and the lesser of the posted usual and
customary fee or the ODB dispensing fee minus the applicable ODB co-payment
amount. Where a completed Side Effect Reporting Form is not available at the
pharmacy during an inspection, the difference between the cost of the higher-cost
product and the lowest DBP listed for the interchangeable category will be
recovered.
(ontario.ca, Revision #17; 2026-08-03 ↗)
6.2 Medically Necessary "No Substitution" Claims
The Ministry will provide reimbursement of a higher-cost interchangeable product in
medically necessary circumstances where a patient has experienced a significant
adverse reaction with two (2) lower-cost interchangeable drug products, where
available. When a prescriber identifies a patient for which it is medically necessary
that a higher cost interchangeable product be provided, the prescriber must:
• Complete, sign and forward to the pharmacist a copy of the Health Canada
side effect reporting form for each lower-cost interchangeable drug product
trialed (Side Effect Reporting Form[s]); and
• Write “No Substitution” or “No Sub” on a written prescription or indicate “No
Substitution” to the pharmacist in the case of a verbal prescription.
The prescriber should keep a copy of the completed form in the patient’s record for
future use and reference.
In the case of a written prescription, when the pharmacist or dispensing physician
receives a prescription with the written notation “No Substitution” or “No Sub”,
reimbursement will be provided for the higher-cost interchangeable product only if
the prescription is accompanied by a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed.
This form must be completely filled out noting the details of the adverse reaction
and signed by the prescriber.
In the case of a verbal prescription, the prescriber must satisfy the operator of the
pharmacy or dispensing physician that a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed
has been completed and signed by the prescriber. A written record of this verbal
prescription and the completed Health Canada Side Effect Reporting Form must be
received by the pharmacy prior to claim submission.
Upon receipt, the pharmacist must:
• Fax, submit online or mail the completed and signed form to Health Canada’s
Canada Vigilance Program; and
• Retain his or her copy of the completed and signed Side Effect Reporting
Form.
(ontario.ca, Revision #17; 2026-08-03 ↗)1 brand, same coverage
Jamp-Celecoxib · DIN 02424541
Manufacturer: Jamp Pharma Corporation; listing date 2015-01-28
Health Canada: Marketed since 2026-03-12 · brand JAMP CELECOXIB · ATC M01AH01 CELECOXIB · form Capsule · route Oral · ingredients CELECOXIB 200 MG · company Jamp pharma corporation · schedule Prescription
Check this DIN again · Health Canada product recordJamp-Celecoxib: Formulary list price $0.2558/unit (unit not stated in source; not the patient's cost)
Ministry pays: $0.2558 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=90923 · Verify on the e-Formulary ↗ (DIN 02424541)
Source record
DIN 02424541: Jamp-Celecoxib
Raw flags: sec12=Y, sec3=Y
Item: 280804076; group id 377; item number 0899; lccId 00064; manufacturer id JPC
Source form: Cap; strength: 200mg
Recorded listing: Limited Use: paid only with a Reason for Use code and the criteria below
Source prices (unrounded): $0.2558; ministry $0.2558
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02424541
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=90923
Therapeutic Notes (formulary)
NSAIDs have a high rate of serious adverse effects in the elderly. When prescribing NSAIDs, the minimal effective dose for the shortest period of time should be used. In nonspecific pain and/or osteoarthritis, in the absence of joint inflammation (swelling), acetaminophen is a better first choice for analgesia. The most effective treatment to prevent NSAID-gastritis is misoprostol; although H-2 antagonists, such as ranitidine or cimetidine, are commonly used, they are not as effective. NSAIDs can significantly aggravate hypertension and congestive heart failure; ASA in doses below 1 gram per day is a better choice than other NSAID options if anti-inflammatory effects are required in patients with these conditions. Low dose ASA has additional benefits for anti-platelet indications that are not provided by other NSAIDs, and should be given in preference or in addition to other NSAIDs for patients with vascular indications.
Interchangeable products
AG-Celecoxib · DIN 02437589 · $0.2558
Act Celecoxib · DIN 02420163 · $0.2558
Apo-Celecoxib · DIN 02418940 · $0.2558
Auro-Celecoxib · DIN 02445689 · $0.2558
Bio-Celecoxib · DIN 02426390 · $0.2558
Celebrex · DIN 02239942 · $0.2558
Celecoxib · DIN 02429683 · $0.2558
Celecoxib · DIN 02436302 · $0.2558
M-Celecoxib · DIN 02495473 · $0.2558
Mar-Celecoxib · DIN 02420066 · $0.2558
Mint-Celecoxib · DIN 02412500 · $0.2558
NRA-Celecoxib · DIN 02479745 · $0.2558
PMS-Celecoxib · DIN 02355450 · $0.2558
PMSC-Celecoxib · DIN 02517124 · $0.2558
Ran-Celecoxib · DIN 02412381 · $0.2558
Sdz Celecoxib · DIN 02442647 · $0.2558
Teva-Celecoxib · DIN 02288923 · $0.2558
Shortage status: resolved shortage (ended 2023-11-15); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02424541
Shortage record checked 2026-09-13T08:10:21.292534+00:00
M-Celecoxib · DIN 02495473 · 200mg · capsule
Limited Use — Reason for Use code 316, 317 requiredMarketed · checked 2026-09-02
Write on scriptLU code 316, 317 (patient must meet the criteria below)
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Ontario Limited Use criteria — code 316, 317
Coverage limit:
Osteoarthritis
Reason for Use code 316
For patients who have failed an adequate trial of acetaminophen (e.g. acetaminophen 1g QID for several weeks) and have had:
Coverage limit:
History of a documented, clinically significant ulcer or GI bleed; or
Failure or intolerance to at least three listed NSAIDS.
Coverage limit:
The maximum daily dose of celecoxib which will be reimbursed for the treatment of osteoarthritis is 200mg.
Coverage limit:
LU Authorization Period: 1 year
Coverage limit:
Rheumatoid arthritis
Reason for Use code 317
For patients who have had:
Coverage limit:
History of a documented, clinically significant ulcer or GI bleed; or
Failure or intolerance to at least three listed NSAIDS.
Coverage limit:
The maximum daily dose of celecoxib which will be reimbursed for the treatment of rheumatoid arthritis is 400mg.
Coverage limit:
LU Authorization Period: 1 year
Brand vs generic price
Lowest DBP recovery rule under medically necessary no-substitution claims:
6.2 Medically Necessary "No Substitution" Claims
The Side Effect Reporting Form will not have to be renewed. However, the
pharmacy must maintain a copy of the prescription that contains a direction that
there be no substitution and the required Health Canada Side Effect Reporting Form
(completed and signed by the prescriber). The prescriber must write “No
Substitution” or “No Sub” on renewal or subsequent new written prescriptions, and
indicate “No Substitution” on subsequent new oral prescriptions. The dispenser will
be reimbursed the DBP plus a mark-up and the lesser of the posted usual and
customary fee or the ODB dispensing fee minus the applicable ODB co-payment
amount. Where a completed Side Effect Reporting Form is not available at the
pharmacy during an inspection, the difference between the cost of the higher-cost
product and the lowest DBP listed for the interchangeable category will be
recovered.
(ontario.ca, Revision #17; 2026-08-03 ↗)
6.2 Medically Necessary "No Substitution" Claims
The Ministry will provide reimbursement of a higher-cost interchangeable product in
medically necessary circumstances where a patient has experienced a significant
adverse reaction with two (2) lower-cost interchangeable drug products, where
available. When a prescriber identifies a patient for which it is medically necessary
that a higher cost interchangeable product be provided, the prescriber must:
• Complete, sign and forward to the pharmacist a copy of the Health Canada
side effect reporting form for each lower-cost interchangeable drug product
trialed (Side Effect Reporting Form[s]); and
• Write “No Substitution” or “No Sub” on a written prescription or indicate “No
Substitution” to the pharmacist in the case of a verbal prescription.
The prescriber should keep a copy of the completed form in the patient’s record for
future use and reference.
In the case of a written prescription, when the pharmacist or dispensing physician
receives a prescription with the written notation “No Substitution” or “No Sub”,
reimbursement will be provided for the higher-cost interchangeable product only if
the prescription is accompanied by a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed.
This form must be completely filled out noting the details of the adverse reaction
and signed by the prescriber.
In the case of a verbal prescription, the prescriber must satisfy the operator of the
pharmacy or dispensing physician that a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed
has been completed and signed by the prescriber. A written record of this verbal
prescription and the completed Health Canada Side Effect Reporting Form must be
received by the pharmacy prior to claim submission.
Upon receipt, the pharmacist must:
• Fax, submit online or mail the completed and signed form to Health Canada’s
Canada Vigilance Program; and
• Retain his or her copy of the completed and signed Side Effect Reporting
Form.
(ontario.ca, Revision #17; 2026-08-03 ↗)1 brand, same coverage
M-Celecoxib · DIN 02495473
Manufacturer: Mantra Pharma Inc.; listing date 2021-10-29
Health Canada: Marketed since 2020-03-24 · brand M-CELECOXIB · ATC M01AH01 CELECOXIB · form Capsule · route Oral · ingredients CELECOXIB 200 MG · company Mantra pharma inc · schedule Prescription
Check this DIN again · Health Canada product recordM-Celecoxib: Formulary list price $0.2558/unit (unit not stated in source; not the patient's cost)
Ministry pays: $0.2558 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=98539 · Verify on the e-Formulary ↗ (DIN 02495473)
Source record
DIN 02495473: M-Celecoxib
Raw flags: sec12=Y, sec3=Y
Item: 280804076; group id 377; item number 0899; lccId 00064; manufacturer id MAT
Source form: Cap; strength: 200mg
Recorded listing: Limited Use: paid only with a Reason for Use code and the criteria below
Source prices (unrounded): $0.2558; ministry $0.2558
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02495473
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=98539
Therapeutic Notes (formulary)
NSAIDs have a high rate of serious adverse effects in the elderly. When prescribing NSAIDs, the minimal effective dose for the shortest period of time should be used. In nonspecific pain and/or osteoarthritis, in the absence of joint inflammation (swelling), acetaminophen is a better first choice for analgesia. The most effective treatment to prevent NSAID-gastritis is misoprostol; although H-2 antagonists, such as ranitidine or cimetidine, are commonly used, they are not as effective. NSAIDs can significantly aggravate hypertension and congestive heart failure; ASA in doses below 1 gram per day is a better choice than other NSAID options if anti-inflammatory effects are required in patients with these conditions. Low dose ASA has additional benefits for anti-platelet indications that are not provided by other NSAIDs, and should be given in preference or in addition to other NSAIDs for patients with vascular indications.
Interchangeable products
AG-Celecoxib · DIN 02437589 · $0.2558
Act Celecoxib · DIN 02420163 · $0.2558
Apo-Celecoxib · DIN 02418940 · $0.2558
Auro-Celecoxib · DIN 02445689 · $0.2558
Bio-Celecoxib · DIN 02426390 · $0.2558
Celebrex · DIN 02239942 · $0.2558
Celecoxib · DIN 02429683 · $0.2558
Celecoxib · DIN 02436302 · $0.2558
Jamp-Celecoxib · DIN 02424541 · $0.2558
Mar-Celecoxib · DIN 02420066 · $0.2558
Mint-Celecoxib · DIN 02412500 · $0.2558
NRA-Celecoxib · DIN 02479745 · $0.2558
PMS-Celecoxib · DIN 02355450 · $0.2558
PMSC-Celecoxib · DIN 02517124 · $0.2558
Ran-Celecoxib · DIN 02412381 · $0.2558
Sdz Celecoxib · DIN 02442647 · $0.2558
Teva-Celecoxib · DIN 02288923 · $0.2558
Shortage status: no shortage or discontinuation reported (checked 2026-09-13T08:10:21.292534+00:00); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02495473
Shortage record checked 2026-09-13T08:10:21.292534+00:00
Mar-Celecoxib · DIN 02420066 · 200mg · capsule
Limited Use — Reason for Use code 316, 317 requiredMarketed · checked 2026-09-02
Write on scriptLU code 316, 317 (patient must meet the criteria below)
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Ontario Limited Use criteria — code 316, 317
Coverage limit:
Osteoarthritis
Reason for Use code 316
For patients who have failed an adequate trial of acetaminophen (e.g. acetaminophen 1g QID for several weeks) and have had:
Coverage limit:
History of a documented, clinically significant ulcer or GI bleed; or
Failure or intolerance to at least three listed NSAIDS.
Coverage limit:
The maximum daily dose of celecoxib which will be reimbursed for the treatment of osteoarthritis is 200mg.
Coverage limit:
LU Authorization Period: 1 year
Coverage limit:
Rheumatoid arthritis
Reason for Use code 317
For patients who have had:
Coverage limit:
History of a documented, clinically significant ulcer or GI bleed; or
Failure or intolerance to at least three listed NSAIDS.
Coverage limit:
The maximum daily dose of celecoxib which will be reimbursed for the treatment of rheumatoid arthritis is 400mg.
Coverage limit:
LU Authorization Period: 1 year
Brand vs generic price
Lowest DBP recovery rule under medically necessary no-substitution claims:
6.2 Medically Necessary "No Substitution" Claims
The Side Effect Reporting Form will not have to be renewed. However, the
pharmacy must maintain a copy of the prescription that contains a direction that
there be no substitution and the required Health Canada Side Effect Reporting Form
(completed and signed by the prescriber). The prescriber must write “No
Substitution” or “No Sub” on renewal or subsequent new written prescriptions, and
indicate “No Substitution” on subsequent new oral prescriptions. The dispenser will
be reimbursed the DBP plus a mark-up and the lesser of the posted usual and
customary fee or the ODB dispensing fee minus the applicable ODB co-payment
amount. Where a completed Side Effect Reporting Form is not available at the
pharmacy during an inspection, the difference between the cost of the higher-cost
product and the lowest DBP listed for the interchangeable category will be
recovered.
(ontario.ca, Revision #17; 2026-08-03 ↗)
6.2 Medically Necessary "No Substitution" Claims
The Ministry will provide reimbursement of a higher-cost interchangeable product in
medically necessary circumstances where a patient has experienced a significant
adverse reaction with two (2) lower-cost interchangeable drug products, where
available. When a prescriber identifies a patient for which it is medically necessary
that a higher cost interchangeable product be provided, the prescriber must:
• Complete, sign and forward to the pharmacist a copy of the Health Canada
side effect reporting form for each lower-cost interchangeable drug product
trialed (Side Effect Reporting Form[s]); and
• Write “No Substitution” or “No Sub” on a written prescription or indicate “No
Substitution” to the pharmacist in the case of a verbal prescription.
The prescriber should keep a copy of the completed form in the patient’s record for
future use and reference.
In the case of a written prescription, when the pharmacist or dispensing physician
receives a prescription with the written notation “No Substitution” or “No Sub”,
reimbursement will be provided for the higher-cost interchangeable product only if
the prescription is accompanied by a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed.
This form must be completely filled out noting the details of the adverse reaction
and signed by the prescriber.
In the case of a verbal prescription, the prescriber must satisfy the operator of the
pharmacy or dispensing physician that a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed
has been completed and signed by the prescriber. A written record of this verbal
prescription and the completed Health Canada Side Effect Reporting Form must be
received by the pharmacy prior to claim submission.
Upon receipt, the pharmacist must:
• Fax, submit online or mail the completed and signed form to Health Canada’s
Canada Vigilance Program; and
• Retain his or her copy of the completed and signed Side Effect Reporting
Form.
(ontario.ca, Revision #17; 2026-08-03 ↗)1 brand, same coverage
Mar-Celecoxib · DIN 02420066
Manufacturer: Marcan Pharmaceuticals Inc.; listing date 2015-01-28
Health Canada: Marketed since 2014-11-17 · brand MAR-CELECOXIB · ATC M01AH01 CELECOXIB · form Capsule · route Oral · ingredients CELECOXIB 200 MG · company Marcan pharmaceuticals inc · schedule Prescription
Check this DIN again · Health Canada product recordMar-Celecoxib: Formulary list price $0.2558/unit (unit not stated in source; not the patient's cost)
Ministry pays: $0.2558 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=90467 · Verify on the e-Formulary ↗ (DIN 02420066)
Source record
DIN 02420066: Mar-Celecoxib
Raw flags: sec12=Y, sec3=Y
Item: 280804076; group id 377; item number 0899; lccId 00064; manufacturer id MAR
Source form: Cap; strength: 200mg
Recorded listing: Limited Use: paid only with a Reason for Use code and the criteria below
Source prices (unrounded): $0.2558; ministry $0.2558
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02420066
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=90467
Therapeutic Notes (formulary)
NSAIDs have a high rate of serious adverse effects in the elderly. When prescribing NSAIDs, the minimal effective dose for the shortest period of time should be used. In nonspecific pain and/or osteoarthritis, in the absence of joint inflammation (swelling), acetaminophen is a better first choice for analgesia. The most effective treatment to prevent NSAID-gastritis is misoprostol; although H-2 antagonists, such as ranitidine or cimetidine, are commonly used, they are not as effective. NSAIDs can significantly aggravate hypertension and congestive heart failure; ASA in doses below 1 gram per day is a better choice than other NSAID options if anti-inflammatory effects are required in patients with these conditions. Low dose ASA has additional benefits for anti-platelet indications that are not provided by other NSAIDs, and should be given in preference or in addition to other NSAIDs for patients with vascular indications.
Interchangeable products
AG-Celecoxib · DIN 02437589 · $0.2558
Act Celecoxib · DIN 02420163 · $0.2558
Apo-Celecoxib · DIN 02418940 · $0.2558
Auro-Celecoxib · DIN 02445689 · $0.2558
Bio-Celecoxib · DIN 02426390 · $0.2558
Celebrex · DIN 02239942 · $0.2558
Celecoxib · DIN 02429683 · $0.2558
Celecoxib · DIN 02436302 · $0.2558
Jamp-Celecoxib · DIN 02424541 · $0.2558
M-Celecoxib · DIN 02495473 · $0.2558
Mint-Celecoxib · DIN 02412500 · $0.2558
NRA-Celecoxib · DIN 02479745 · $0.2558
PMS-Celecoxib · DIN 02355450 · $0.2558
PMSC-Celecoxib · DIN 02517124 · $0.2558
Ran-Celecoxib · DIN 02412381 · $0.2558
Sdz Celecoxib · DIN 02442647 · $0.2558
Teva-Celecoxib · DIN 02288923 · $0.2558
Shortage status: no shortage or discontinuation reported (checked 2026-09-13T08:10:21.292534+00:00); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02420066
Shortage record checked 2026-09-13T08:10:21.292534+00:00
Mint-Celecoxib · DIN 02412500 · 200mg · capsule
Limited Use — Reason for Use code 316, 317 requiredMarketed · checked 2026-09-02
Write on scriptLU code 316, 317 (patient must meet the criteria below)
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Ontario Limited Use criteria — code 316, 317
Coverage limit:
Osteoarthritis
Reason for Use code 316
For patients who have failed an adequate trial of acetaminophen (e.g. acetaminophen 1g QID for several weeks) and have had:
Coverage limit:
History of a documented, clinically significant ulcer or GI bleed; or
Failure or intolerance to at least three listed NSAIDS.
Coverage limit:
The maximum daily dose of celecoxib which will be reimbursed for the treatment of osteoarthritis is 200mg.
Coverage limit:
LU Authorization Period: 1 year
Coverage limit:
Rheumatoid arthritis
Reason for Use code 317
For patients who have had:
Coverage limit:
History of a documented, clinically significant ulcer or GI bleed; or
Failure or intolerance to at least three listed NSAIDS.
Coverage limit:
The maximum daily dose of celecoxib which will be reimbursed for the treatment of rheumatoid arthritis is 400mg.
Coverage limit:
LU Authorization Period: 1 year
Brand vs generic price
Lowest DBP recovery rule under medically necessary no-substitution claims:
6.2 Medically Necessary "No Substitution" Claims
The Side Effect Reporting Form will not have to be renewed. However, the
pharmacy must maintain a copy of the prescription that contains a direction that
there be no substitution and the required Health Canada Side Effect Reporting Form
(completed and signed by the prescriber). The prescriber must write “No
Substitution” or “No Sub” on renewal or subsequent new written prescriptions, and
indicate “No Substitution” on subsequent new oral prescriptions. The dispenser will
be reimbursed the DBP plus a mark-up and the lesser of the posted usual and
customary fee or the ODB dispensing fee minus the applicable ODB co-payment
amount. Where a completed Side Effect Reporting Form is not available at the
pharmacy during an inspection, the difference between the cost of the higher-cost
product and the lowest DBP listed for the interchangeable category will be
recovered.
(ontario.ca, Revision #17; 2026-08-03 ↗)
6.2 Medically Necessary "No Substitution" Claims
The Ministry will provide reimbursement of a higher-cost interchangeable product in
medically necessary circumstances where a patient has experienced a significant
adverse reaction with two (2) lower-cost interchangeable drug products, where
available. When a prescriber identifies a patient for which it is medically necessary
that a higher cost interchangeable product be provided, the prescriber must:
• Complete, sign and forward to the pharmacist a copy of the Health Canada
side effect reporting form for each lower-cost interchangeable drug product
trialed (Side Effect Reporting Form[s]); and
• Write “No Substitution” or “No Sub” on a written prescription or indicate “No
Substitution” to the pharmacist in the case of a verbal prescription.
The prescriber should keep a copy of the completed form in the patient’s record for
future use and reference.
In the case of a written prescription, when the pharmacist or dispensing physician
receives a prescription with the written notation “No Substitution” or “No Sub”,
reimbursement will be provided for the higher-cost interchangeable product only if
the prescription is accompanied by a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed.
This form must be completely filled out noting the details of the adverse reaction
and signed by the prescriber.
In the case of a verbal prescription, the prescriber must satisfy the operator of the
pharmacy or dispensing physician that a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed
has been completed and signed by the prescriber. A written record of this verbal
prescription and the completed Health Canada Side Effect Reporting Form must be
received by the pharmacy prior to claim submission.
Upon receipt, the pharmacist must:
• Fax, submit online or mail the completed and signed form to Health Canada’s
Canada Vigilance Program; and
• Retain his or her copy of the completed and signed Side Effect Reporting
Form.
(ontario.ca, Revision #17; 2026-08-03 ↗)1 brand, same coverage
Mint-Celecoxib · DIN 02412500
Manufacturer: Mint Pharmaceuticals Inc.; listing date 2015-01-28
Health Canada: Marketed since 2014-11-17 · brand MINT-CELECOXIB · ATC M01AH01 CELECOXIB · form Capsule · route Oral · ingredients CELECOXIB 200 MG · company Mint pharmaceuticals inc · schedule Prescription
Check this DIN again · Health Canada product recordMint-Celecoxib: Formulary list price $0.2558/unit (unit not stated in source; not the patient's cost)
Ministry pays: $0.2558 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=89714 · Verify on the e-Formulary ↗ (DIN 02412500)
Source record
DIN 02412500: Mint-Celecoxib
Raw flags: sec12=Y, sec3=Y
Item: 280804076; group id 377; item number 0899; lccId 00064; manufacturer id MIN
Source form: Cap; strength: 200mg
Recorded listing: Limited Use: paid only with a Reason for Use code and the criteria below
Source prices (unrounded): $0.2558; ministry $0.2558
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02412500
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=89714
Therapeutic Notes (formulary)
NSAIDs have a high rate of serious adverse effects in the elderly. When prescribing NSAIDs, the minimal effective dose for the shortest period of time should be used. In nonspecific pain and/or osteoarthritis, in the absence of joint inflammation (swelling), acetaminophen is a better first choice for analgesia. The most effective treatment to prevent NSAID-gastritis is misoprostol; although H-2 antagonists, such as ranitidine or cimetidine, are commonly used, they are not as effective. NSAIDs can significantly aggravate hypertension and congestive heart failure; ASA in doses below 1 gram per day is a better choice than other NSAID options if anti-inflammatory effects are required in patients with these conditions. Low dose ASA has additional benefits for anti-platelet indications that are not provided by other NSAIDs, and should be given in preference or in addition to other NSAIDs for patients with vascular indications.
Interchangeable products
AG-Celecoxib · DIN 02437589 · $0.2558
Act Celecoxib · DIN 02420163 · $0.2558
Apo-Celecoxib · DIN 02418940 · $0.2558
Auro-Celecoxib · DIN 02445689 · $0.2558
Bio-Celecoxib · DIN 02426390 · $0.2558
Celebrex · DIN 02239942 · $0.2558
Celecoxib · DIN 02429683 · $0.2558
Celecoxib · DIN 02436302 · $0.2558
Jamp-Celecoxib · DIN 02424541 · $0.2558
M-Celecoxib · DIN 02495473 · $0.2558
Mar-Celecoxib · DIN 02420066 · $0.2558
NRA-Celecoxib · DIN 02479745 · $0.2558
PMS-Celecoxib · DIN 02355450 · $0.2558
PMSC-Celecoxib · DIN 02517124 · $0.2558
Ran-Celecoxib · DIN 02412381 · $0.2558
Sdz Celecoxib · DIN 02442647 · $0.2558
Teva-Celecoxib · DIN 02288923 · $0.2558
Shortage status: no shortage or discontinuation reported (checked 2026-09-13T08:10:21.292534+00:00); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02412500
Shortage record checked 2026-09-13T08:10:21.292534+00:00