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Ontario coverage, price, criteria word for word, Health Canada status and shortages for one product

Patient plan: look up a medication list

ESZOPICLONE

All strengths: Off-Formulary Interchangeable, not an ODB benefit; same patient cost rules

Shared coverage and patient cost rules
StatusOff-Formulary Interchangeable, not an ODB benefit
Patient paysPatient pays: program not supplied; amount cannot be determined.

Other products in the same Health Canada class (N05C, N05CF) — coverage varies; not interchangeable

  • Zolpidem (Sublinox): not a benefit
  • Zopiclone (Imovane): not a benefit
  • Flurazepam (Dalmane): general benefit, Not a benefit
  • Nitrazepam (Mogadon): general benefit
  • Temazepam (Restoril): general benefit
  • Triazolam (Halcion): general benefit, Not a benefit

1 more in the class list below

Lunesta · DIN 02453207 · 1mg · tablet

Off-Formulary Interchangeable, not an ODB benefitMarketed · checked 2026-09-02
Write on scriptnot a benefit; no Exceptional Access criteria on record; see alternatives
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
1 brand, same coverage
Lunesta · DIN 02453207 Manufacturer: Knight Therapeutics Inc.; listing date 2024-10-31 Health Canada: Marketed since 2026-01-20 · brand LUNESTA · ATC N05CF04 ESZOPICLONE · form Tablet · route Oral · ingredients ESZOPICLONE 1 MG · company Knight therapeutics inc. · schedule Prescription
Check this DIN again · Health Canada product record

Lunesta: Formulary list price not recorded/unit (unit not stated in source; not the patient's cost)

Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=93974 · Verify on the e-Formulary ↗ (DIN 02453207)

Source record
DIN 02453207: Lunesta Raw flags: notABenefit=Y, sec3=Y, sec3b=Y Item: 282400240; group id 520; item number 1407; lccId None; manufacturer id KNT Source form: Tab; strength: 1mg Recorded listing: Off-Formulary Interchangeable, not an ODB benefit Source prices (unrounded): not recorded; ministry not recorded Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02453207 Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=93974
Interchangeable products
Mar-Eszopiclone · DIN 02549433 · not recorded
Shortage status: resolved shortage (ended 2024-08-30); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada) Source: https://healthproductshortages.ca/search?term=02453207
Shortage record checked 2026-09-13T08:10:21.292534+00:00

Mar-Eszopiclone · DIN 02549433 · 1mg · tablet

Off-Formulary Interchangeable, not an ODB benefitMarketed · checked 2026-09-02
Write on scriptnot a benefit; no Exceptional Access criteria on record; see alternatives
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
1 brand, same coverage
Mar-Eszopiclone · DIN 02549433 Manufacturer: Marcan Pharmaceuticals Inc.; listing date 2024-10-31 Health Canada: Marketed since 2024-09-03 · brand MAR-ESZOPICLONE · ATC N05CF04 ESZOPICLONE · form Tablet · route Oral · ingredients ESZOPICLONE 1 MG · company Marcan pharmaceuticals inc · schedule Prescription
Check this DIN again · Health Canada product record

Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=103828 · Verify on the e-Formulary ↗ (DIN 02549433)

Source record
DIN 02549433: Mar-Eszopiclone Raw flags: notABenefit=Y, sec3=Y, sec3b=Y Item: 282400240; group id 520; item number 1407; lccId None; manufacturer id MAR Source form: Tab; strength: 1mg Recorded listing: Off-Formulary Interchangeable, not an ODB benefit Source prices (unrounded): $1.4365; ministry not recorded Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02549433 Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=103828
Interchangeable products
Lunesta · DIN 02453207 · not recorded
Shortage status: no shortage or discontinuation reported (checked 2026-09-13T08:10:21.292534+00:00); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada) Source: https://healthproductshortages.ca/search?term=02549433
Shortage record checked 2026-09-13T08:10:21.292534+00:00

Lunesta · DIN 02453215 · 2mg · tablet

Off-Formulary Interchangeable, not an ODB benefitMarketed · checked 2026-09-02
Write on scriptnot a benefit; no Exceptional Access criteria on record; see alternatives
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
1 brand, same coverage
Lunesta · DIN 02453215 Manufacturer: Knight Therapeutics Inc.; listing date 2024-10-31 Health Canada: Marketed since 2026-01-20 · brand LUNESTA · ATC N05CF04 ESZOPICLONE · form Tablet · route Oral · ingredients ESZOPICLONE 2 MG · company Knight therapeutics inc. · schedule Prescription
Check this DIN again · Health Canada product record

Lunesta: Formulary list price not recorded/unit (unit not stated in source; not the patient's cost)

Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=93975 · Verify on the e-Formulary ↗ (DIN 02453215)

Source record
DIN 02453215: Lunesta Raw flags: notABenefit=Y, sec3=Y, sec3b=Y Item: 282400241; group id 520; item number 1408; lccId None; manufacturer id KNT Source form: Tab; strength: 2mg Recorded listing: Off-Formulary Interchangeable, not an ODB benefit Source prices (unrounded): not recorded; ministry not recorded Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02453215 Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=93975
Interchangeable products
Mar-Eszopiclone · DIN 02549441 · not recorded
Shortage status: no shortage or discontinuation reported (checked 2026-09-13T08:10:21.292534+00:00); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada) Source: https://healthproductshortages.ca/search?term=02453215
Shortage record checked 2026-09-13T08:10:21.292534+00:00

Mar-Eszopiclone · DIN 02549441 · 2mg · tablet

Off-Formulary Interchangeable, not an ODB benefitMarketed · checked 2026-09-02
Write on scriptnot a benefit; no Exceptional Access criteria on record; see alternatives
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
1 brand, same coverage
Mar-Eszopiclone · DIN 02549441 Manufacturer: Marcan Pharmaceuticals Inc.; listing date 2024-10-31 Health Canada: Marketed since 2024-09-03 · brand MAR-ESZOPICLONE · ATC N05CF04 ESZOPICLONE · form Tablet · route Oral · ingredients ESZOPICLONE 2 MG · company Marcan pharmaceuticals inc · schedule Prescription
Check this DIN again · Health Canada product record

Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=103829 · Verify on the e-Formulary ↗ (DIN 02549441)

Source record
DIN 02549441: Mar-Eszopiclone Raw flags: notABenefit=Y, sec3=Y, sec3b=Y Item: 282400241; group id 520; item number 1408; lccId None; manufacturer id MAR Source form: Tab; strength: 2mg Recorded listing: Off-Formulary Interchangeable, not an ODB benefit Source prices (unrounded): $1.4365; ministry not recorded Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02549441 Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=103829
Interchangeable products
Lunesta · DIN 02453215 · not recorded
Shortage status: no shortage or discontinuation reported (checked 2026-09-13T08:10:21.292534+00:00); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada) Source: https://healthproductshortages.ca/search?term=02549441
Shortage record checked 2026-09-13T08:10:21.292534+00:00

Lunesta · DIN 02453223 · 3mg · tablet

Off-Formulary Interchangeable, not an ODB benefitMarketed · checked 2026-09-02
Write on scriptnot a benefit; no Exceptional Access criteria on record; see alternatives
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
1 brand, same coverage
Lunesta · DIN 02453223 Manufacturer: Knight Therapeutics Inc.; listing date 2024-10-31 Health Canada: Marketed since 2026-01-22 · brand LUNESTA · ATC N05CF04 ESZOPICLONE · form Tablet · route Oral · ingredients ESZOPICLONE 3 MG · company Knight therapeutics inc. · schedule Prescription
Check this DIN again · Health Canada product record

Lunesta: Formulary list price not recorded/unit (unit not stated in source; not the patient's cost)

Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=93976 · Verify on the e-Formulary ↗ (DIN 02453223)

Source record
DIN 02453223: Lunesta Raw flags: notABenefit=Y, sec3=Y, sec3b=Y Item: 282400242; group id 520; item number 1409; lccId None; manufacturer id KNT Source form: Tab; strength: 3mg Recorded listing: Off-Formulary Interchangeable, not an ODB benefit Source prices (unrounded): not recorded; ministry not recorded Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02453223 Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=93976
Interchangeable products
Mar-Eszopiclone · DIN 02549468 · not recorded
Shortage status: resolved shortage (ended 2024-12-17); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada) Source: https://healthproductshortages.ca/search?term=02453223
Shortage record checked 2026-09-13T08:10:21.292534+00:00

Mar-Eszopiclone · DIN 02549468 · 3mg · tablet

Off-Formulary Interchangeable, not an ODB benefitMarketed · checked 2026-09-02
Write on scriptnot a benefit; no Exceptional Access criteria on record; see alternatives
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
1 brand, same coverage
Mar-Eszopiclone · DIN 02549468 Manufacturer: Marcan Pharmaceuticals Inc.; listing date 2024-10-31 Health Canada: Marketed since 2024-09-03 · brand MAR-ESZOPICLONE · ATC N05CF04 ESZOPICLONE · form Tablet · route Oral · ingredients ESZOPICLONE 3 MG · company Marcan pharmaceuticals inc · schedule Prescription
Check this DIN again · Health Canada product record

Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=103830 · Verify on the e-Formulary ↗ (DIN 02549468)

Source record
DIN 02549468: Mar-Eszopiclone Raw flags: notABenefit=Y, sec3=Y, sec3b=Y Item: 282400242; group id 520; item number 1409; lccId None; manufacturer id MAR Source form: Tab; strength: 3mg Recorded listing: Off-Formulary Interchangeable, not an ODB benefit Source prices (unrounded): $1.4365; ministry not recorded Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02549468 Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=103830
Interchangeable products
Lunesta · DIN 02453223 · not recorded
Shortage status: no shortage or discontinuation reported (checked 2026-09-13T08:10:21.292534+00:00); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada) Source: https://healthproductshortages.ca/search?term=02549468
Shortage record checked 2026-09-13T08:10:21.292534+00:00
Other drugs in the same formulary class (28:24 Sedatives and Hypnotics) and how they are covered

Matched class: 28:24 Sedatives and Hypnotics

Drug-class inventory only. Lists recorded Ontario formulary products, not every Canadian medication; does not recommend treatment. Covered without a code on the Ontario formulary: NITRAZEPAM, PHENOBARBITAL, TEMAZEPAM Some products covered without a code (check the product listing): BUSPIRONE HYDROCHLORIDE, FLURAZEPAM, METHOTRIMEPRAZINE, TRIAZOLAM 28:24 Sedatives and Hypnotics

ZOLPIDEM TARTRATE

· 10 products · Off-Formulary Interchangeable, not an ODB benefit · strengths: 5mg, 10mg · SL Tab

ZOPICLONE

· 40 products · Off-Formulary Interchangeable, not an ODB benefit · strengths: 3.75mg, 5mg, 7.5mg · Tab

FLURAZEPAM

· 4 products · Listed, not a benefit (2), General benefit (2) · strengths: 15mg, 30mg · Cap

NITRAZEPAM

· 2 products · General benefit · strengths: 5mg, 10mg · Tab

TEMAZEPAM

· 2 products · General benefit · strengths: 15mg, 30mg · Cap

TRIAZOLAM

· 4 products · Listed, not a benefit (2), General benefit (2) · strengths: 0.125mg, 0.25mg · Tab

MIDAZOLAM

· 3 products · Listed, not a benefit (1), Limited Use, codes 495, 496 (2) · strengths: 5mg/mL · Inj Sol (with Preservative)

BUSPIRONE HYDROCHLORIDE

· 9 products · Listed, not a benefit (1), General benefit (8) · strengths: 10mg · Tab

METHOTRIMEPRAZINE

· 9 products · General benefit (5), Listed, not a benefit (4) · strengths: 25mg/mL, 2mg, 5mg, 25mg, 50mg · Inj Sol-1mL Pk, Tab

PHENOBARBITAL

· 5 products · General benefit · strengths: 5mg/mL, 15mg, 30mg, 60mg, 100mg · Oral Elixir, Tab

LORAZEPAM

· 9 products · Listed, not a benefit (1), Limited Use, codes 481 (2), Off-Formulary Interchangeable, not an ODB benefit (6) · strengths: 4mg/mL, 0.5mg, 1mg, 2mg · Inj Sol (with preservative), SL Tab Source: formulary-ed43-front-matter.txt Part V; ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26; class 28:24
Full class listing Related classes: 28:08 Analgesics, 28:10 Opiate Antagonists, 28:12 Anticonvulsants, 28:16 Psychotherapeutic Agents, 28:20 C.N.S. Stimulants, 28:36 Antiparkinsonian Agents, 28:92 Miscellaneous Central Nervous System Drugs Same formulary class, not same indication: class membership alone does not establish equivalent uses.
What the Health Canada label says it is for
1. INDICATIONS LUNESTA (eszopiclone) is indicated for short-term (usually not exceeding 7-10 days) use for: • treatment and symptomatic relief of insomnia characterized by difficulty falling asleep • frequent nocturnal awakenings and/or early morning awakenings where disturbed sleep results in impaired daytime functioning (see 4.4 DOSAGE AND ADMINISTRATION, 4.1 Dosing Considerations). 1.1 Pediatrics Pediatrics (<18 years of age): No data are available to Health Canada; therefore, Health Canada has not authorized an indication for pediatric use. [see also 7.1.3 Pediatrics]. 1.2 Geriatrics Geriatrics (>65 years of age): There is a risk for greater sensitivity to the drug effects in the elderly [see also 7.1.4 Geriatrics]. A lower maximum dose is recommended in the elderly (see 4.2 Recommended Dose and Dosage Adjustment, Geriatrics). Long-term use of LUNESTA should be avoided, including in geriatric patients. Enhanced monitoring is recommended (see 7 WARNINGS AND PRECAUTIONS, Falls and Fractures; 4 DOSAGE AND ADMINISTRATION, 4.1 Dosing Considerations). https://pdf.hres.ca/dpd_pm/00075298.PDF PM date: APR 18, 2024 Source product: LUNESTA; DIN 02453207; fetched 2026-09-10 Product monograph posted by Health Canada; excerpt for lookup only.

Other review policies

For Lunesta, Mar-Eszopiclone: no applicable EAP criteria are held and no ODB benefit is established. These policies do not establish coverage.

For rare, immediately life-, limb- or organ-threatening circumstances, the Compassionate Review Policy may consider an unfunded drug or indication, subject to its criteria and without bypassing the drug review process. Compassionate Review Policy

Compassionate Review Policy: source quote
Where there are rare clinical circumstances in immediately life, limb, or organ-threatening conditions, the Executive Officer will also consider requests for drugs or indications in situations where there has not been a decision by the Executive Officer to provide funding of the drug or indication as part of the Ontario Drug Benefit program (and the EAP), and the drug or indication requested would not circumvent the established review process for new drugs or indications as part of the drug submission process for listing within the Ontario Drug Benefit program. Requests must meet the criteria for the Compassionate Review Policy.

Ontario source; updated September 15, 2026

For cancer drugs, Case-by-Case Review considers rare, immediately life-threatening circumstances when no satisfactory funded treatment exists; its criteria and application process apply. Case-by-Case Review (cancer drugs)

Case-by-Case Review (cancer drugs): source quote
Note: Requests for cancer drugs are considered under the Case-by-Case Review Program (CBCRP) which is administered by Ontario Health (Cancer Care Ontario) on behalf of the Ministry of Health. The CBCRP considers funding requests for drugs (both oral therapies and injectable drugs) for the treatment of cancer in patients who have a rare clinical circumstance that is immediately life-threatening (death is likely within a matter of months) and who require treatment with an unfunded drug, because there is no other satisfactory and funded treatment. Please refer to the Ontario Health website for information on the application process, FAQs, eligibility criteria and program policies.

Ontario source; updated September 15, 2026