VENLAFAXINE HCL
All strengths: General benefit; same patient cost rules
Shared coverage and patient cost rules
StatusGeneral benefit
Patient paysPatient pays: program not supplied; amount cannot be determined.
Other products in the same Health Canada class (N06AX) — coverage varies; not interchangeable
- Duloxetine (Cymbalta): general benefit, Not a benefit
- Mirtazapine (Remeron RD): general benefit, Not a benefit
- Trazodone (Desyrel): general benefit, Not a benefit
- Vortioxetine (Trintellix): general benefit
- Bupropion (Wellbutrin XL): limited Use 315, Not a benefit
- Desvenlafaxine (Pristiq): not a benefit
17 more in the class list below
ACT Venlafaxine XR · DIN 02304317 · 37.5mg · extended release capsule
General benefitMarketed · checked 2026-09-02
Write on scriptno code needed
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Brand vs generic price
Lowest DBP recovery rule under medically necessary no-substitution claims:
6.2 Medically Necessary "No Substitution" Claims
The Side Effect Reporting Form will not have to be renewed. However, the
pharmacy must maintain a copy of the prescription that contains a direction that
there be no substitution and the required Health Canada Side Effect Reporting Form
(completed and signed by the prescriber). The prescriber must write “No
Substitution” or “No Sub” on renewal or subsequent new written prescriptions, and
indicate “No Substitution” on subsequent new oral prescriptions. The dispenser will
be reimbursed the DBP plus a mark-up and the lesser of the posted usual and
customary fee or the ODB dispensing fee minus the applicable ODB co-payment
amount. Where a completed Side Effect Reporting Form is not available at the
pharmacy during an inspection, the difference between the cost of the higher-cost
product and the lowest DBP listed for the interchangeable category will be
recovered.
(ontario.ca, Revision #17; 2026-08-03 ↗)
6.2 Medically Necessary "No Substitution" Claims
The Ministry will provide reimbursement of a higher-cost interchangeable product in
medically necessary circumstances where a patient has experienced a significant
adverse reaction with two (2) lower-cost interchangeable drug products, where
available. When a prescriber identifies a patient for which it is medically necessary
that a higher cost interchangeable product be provided, the prescriber must:
• Complete, sign and forward to the pharmacist a copy of the Health Canada
side effect reporting form for each lower-cost interchangeable drug product
trialed (Side Effect Reporting Form[s]); and
• Write “No Substitution” or “No Sub” on a written prescription or indicate “No
Substitution” to the pharmacist in the case of a verbal prescription.
The prescriber should keep a copy of the completed form in the patient’s record for
future use and reference.
In the case of a written prescription, when the pharmacist or dispensing physician
receives a prescription with the written notation “No Substitution” or “No Sub”,
reimbursement will be provided for the higher-cost interchangeable product only if
the prescription is accompanied by a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed.
This form must be completely filled out noting the details of the adverse reaction
and signed by the prescriber.
In the case of a verbal prescription, the prescriber must satisfy the operator of the
pharmacy or dispensing physician that a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed
has been completed and signed by the prescriber. A written record of this verbal
prescription and the completed Health Canada Side Effect Reporting Form must be
received by the pharmacy prior to claim submission.
Upon receipt, the pharmacist must:
• Fax, submit online or mail the completed and signed form to Health Canada’s
Canada Vigilance Program; and
• Retain his or her copy of the completed and signed Side Effect Reporting
Form.
(ontario.ca, Revision #17; 2026-08-03 ↗)1 brand, same coverage
ACT Venlafaxine XR · DIN 02304317
Manufacturer: Teva Canada Limited; listing date 2008-04-09
Health Canada: Marketed since 2019-03-01 · brand ACT VENLAFAXINE XR · ATC N06AX16 VENLAFAXINE · form Capsule (extended-release) · route Oral · ingredients VENLAFAXINE (VENLAFAXINE HYDROCHLORIDE) 37.5 MG · company Teva canada limited · schedule Prescription
Check this DIN again · Health Canada product recordACT Venlafaxine XR: Formulary list price $0.0913/unit (unit not stated in source; not the patient's cost)
Ministry pays: $0.0913 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=78960 · Verify on the e-Formulary ↗ (DIN 02304317)
Source record
DIN 02304317: ACT Venlafaxine XR
Raw flags: sec3=Y
Item: 281604087; group id 474; item number 1193; lccId None; manufacturer id TEV
Source form: ER Cap; strength: 37.5mg
Recorded listing: General benefit
Source prices (unrounded): $0.0913; ministry $0.0913
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02304317
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=78960
Interchangeable products
Apo-Venlafaxine XR · DIN 02331683 · $0.0913
Auro-Venlafaxine XR · DIN 02452839 · $0.0913
Effexor XR · DIN 02237279 · $0.0913
M-Venlafaxine XR · DIN 02471280 · $0.0913
Mint-Venlafaxine XR · DIN 02522977 · $0.0913
PMS-Venlafaxine XR · DIN 02278545 · $0.0913
PMSC-Venlafaxine XR · DIN 02521466 · $0.0913
Sandoz Venlafaxine XR · DIN 02310317 · $0.0913
Taro-Venlafaxine XR · DIN 02380072 · $0.0913
Teva-Venlafaxine XR · DIN 02275023 · $0.0913
Venlafaxine XR · DIN 02354713 · $0.0913
Venlafaxine XR · DIN 02385929 · $0.0913
Venlafaxine XR · DIN 02489678 · $0.0913
Venlafaxine XR · DIN 02516535 · $0.0913
Shortage status: discontinued (2018-06-30, reported by ACTAVIS PHARMA COMPANY); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02304317
Shortage record checked 2026-09-13T08:10:21.292534+00:00
Auro-Venlafaxine XR · DIN 02452839 · 37.5mg · extended release capsule
General benefitMarketed · checked 2026-09-02
Write on scriptno code needed
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Brand vs generic price
Lowest DBP recovery rule under medically necessary no-substitution claims:
6.2 Medically Necessary "No Substitution" Claims
The Side Effect Reporting Form will not have to be renewed. However, the
pharmacy must maintain a copy of the prescription that contains a direction that
there be no substitution and the required Health Canada Side Effect Reporting Form
(completed and signed by the prescriber). The prescriber must write “No
Substitution” or “No Sub” on renewal or subsequent new written prescriptions, and
indicate “No Substitution” on subsequent new oral prescriptions. The dispenser will
be reimbursed the DBP plus a mark-up and the lesser of the posted usual and
customary fee or the ODB dispensing fee minus the applicable ODB co-payment
amount. Where a completed Side Effect Reporting Form is not available at the
pharmacy during an inspection, the difference between the cost of the higher-cost
product and the lowest DBP listed for the interchangeable category will be
recovered.
(ontario.ca, Revision #17; 2026-08-03 ↗)
6.2 Medically Necessary "No Substitution" Claims
The Ministry will provide reimbursement of a higher-cost interchangeable product in
medically necessary circumstances where a patient has experienced a significant
adverse reaction with two (2) lower-cost interchangeable drug products, where
available. When a prescriber identifies a patient for which it is medically necessary
that a higher cost interchangeable product be provided, the prescriber must:
• Complete, sign and forward to the pharmacist a copy of the Health Canada
side effect reporting form for each lower-cost interchangeable drug product
trialed (Side Effect Reporting Form[s]); and
• Write “No Substitution” or “No Sub” on a written prescription or indicate “No
Substitution” to the pharmacist in the case of a verbal prescription.
The prescriber should keep a copy of the completed form in the patient’s record for
future use and reference.
In the case of a written prescription, when the pharmacist or dispensing physician
receives a prescription with the written notation “No Substitution” or “No Sub”,
reimbursement will be provided for the higher-cost interchangeable product only if
the prescription is accompanied by a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed.
This form must be completely filled out noting the details of the adverse reaction
and signed by the prescriber.
In the case of a verbal prescription, the prescriber must satisfy the operator of the
pharmacy or dispensing physician that a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed
has been completed and signed by the prescriber. A written record of this verbal
prescription and the completed Health Canada Side Effect Reporting Form must be
received by the pharmacy prior to claim submission.
Upon receipt, the pharmacist must:
• Fax, submit online or mail the completed and signed form to Health Canada’s
Canada Vigilance Program; and
• Retain his or her copy of the completed and signed Side Effect Reporting
Form.
(ontario.ca, Revision #17; 2026-08-03 ↗)1 brand, same coverage
Auro-Venlafaxine XR · DIN 02452839
Manufacturer: Auro Pharma Inc.; listing date 2016-05-31
Health Canada: Marketed since 2016-03-14 · brand AURO-VENLAFAXINE XR · ATC N06AX16 VENLAFAXINE · form Capsule (extended-release) · route Oral · ingredients VENLAFAXINE (VENLAFAXINE HYDROCHLORIDE) 37.5 MG · company Auro pharma inc · schedule Prescription
Check this DIN again · Health Canada product recordAuro-Venlafaxine XR: Formulary list price $0.0913/unit (unit not stated in source; not the patient's cost)
Ministry pays: $0.0913 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=93924 · Verify on the e-Formulary ↗ (DIN 02452839)
Source record
DIN 02452839: Auro-Venlafaxine XR
Raw flags: sec3=Y
Item: 281604087; group id 474; item number 1193; lccId None; manufacturer id AUR
Source form: ER Cap; strength: 37.5mg
Recorded listing: General benefit
Source prices (unrounded): $0.0913; ministry $0.0913
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02452839
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=93924
Interchangeable products
ACT Venlafaxine XR · DIN 02304317 · $0.0913
Apo-Venlafaxine XR · DIN 02331683 · $0.0913
Effexor XR · DIN 02237279 · $0.0913
M-Venlafaxine XR · DIN 02471280 · $0.0913
Mint-Venlafaxine XR · DIN 02522977 · $0.0913
PMS-Venlafaxine XR · DIN 02278545 · $0.0913
PMSC-Venlafaxine XR · DIN 02521466 · $0.0913
Sandoz Venlafaxine XR · DIN 02310317 · $0.0913
Taro-Venlafaxine XR · DIN 02380072 · $0.0913
Teva-Venlafaxine XR · DIN 02275023 · $0.0913
Venlafaxine XR · DIN 02354713 · $0.0913
Venlafaxine XR · DIN 02385929 · $0.0913
Venlafaxine XR · DIN 02489678 · $0.0913
Venlafaxine XR · DIN 02516535 · $0.0913
Shortage status: resolved shortage (ended 2024-12-16); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02452839
Shortage record checked 2026-09-13T08:10:21.292534+00:00
Effexor XR · DIN 02237279 · 37.5mg · extended release capsule
General benefitMarketed · checked 2026-09-02
Write on scriptno code needed
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Savings card: RxHelp ONE lists Effexor XR (read 2026-09-10) — brand-name savings card, free; cannot be combined with another card on the same claim.
(rxhelp.ca ↗)1 brand, same coverage
Effexor XR · DIN 02237279
Manufacturer: Upjohn Canada ULC; listing date 2000-01-17
Health Canada: Marketed since 2023-08-09 · brand EFFEXOR XR · ATC N06AX16 VENLAFAXINE · form Capsule (extended-release) · route Oral · ingredients VENLAFAXINE (VENLAFAXINE HYDROCHLORIDE) 37.5 MG · company Bgp pharma ulc · schedule Prescription
Check this DIN again · Health Canada product recordMinistry pays: $0.0913 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=60600 · Verify on the e-Formulary ↗ (DIN 02237279)
Source record
DIN 02237279: Effexor XR
Raw flags: sec3=Y
Item: 281604087; group id 474; item number 1193; lccId None; manufacturer id UJC
Source form: ER Cap; strength: 37.5mg
Recorded listing: General benefit
Source prices (unrounded): $1.1625; ministry $0.0913
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02237279
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=60600
Interchangeable products
ACT Venlafaxine XR · DIN 02304317 · $0.0913
Apo-Venlafaxine XR · DIN 02331683 · $0.0913
Auro-Venlafaxine XR · DIN 02452839 · $0.0913
M-Venlafaxine XR · DIN 02471280 · $0.0913
Mint-Venlafaxine XR · DIN 02522977 · $0.0913
PMS-Venlafaxine XR · DIN 02278545 · $0.0913
PMSC-Venlafaxine XR · DIN 02521466 · $0.0913
Sandoz Venlafaxine XR · DIN 02310317 · $0.0913
Taro-Venlafaxine XR · DIN 02380072 · $0.0913
Teva-Venlafaxine XR · DIN 02275023 · $0.0913
Venlafaxine XR · DIN 02354713 · $0.0913
Venlafaxine XR · DIN 02385929 · $0.0913
Venlafaxine XR · DIN 02489678 · $0.0913
Venlafaxine XR · DIN 02516535 · $0.0913
Shortage status: resolved shortage (ended 2023-12-07); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02237279
Shortage record checked 2026-09-13T08:10:21.292534+00:00
M-Venlafaxine XR · DIN 02471280 · 37.5mg · extended release capsule
General benefitMarketed · checked 2026-09-02
Write on scriptno code needed
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Brand vs generic price
Lowest DBP recovery rule under medically necessary no-substitution claims:
6.2 Medically Necessary "No Substitution" Claims
The Side Effect Reporting Form will not have to be renewed. However, the
pharmacy must maintain a copy of the prescription that contains a direction that
there be no substitution and the required Health Canada Side Effect Reporting Form
(completed and signed by the prescriber). The prescriber must write “No
Substitution” or “No Sub” on renewal or subsequent new written prescriptions, and
indicate “No Substitution” on subsequent new oral prescriptions. The dispenser will
be reimbursed the DBP plus a mark-up and the lesser of the posted usual and
customary fee or the ODB dispensing fee minus the applicable ODB co-payment
amount. Where a completed Side Effect Reporting Form is not available at the
pharmacy during an inspection, the difference between the cost of the higher-cost
product and the lowest DBP listed for the interchangeable category will be
recovered.
(ontario.ca, Revision #17; 2026-08-03 ↗)
6.2 Medically Necessary "No Substitution" Claims
The Ministry will provide reimbursement of a higher-cost interchangeable product in
medically necessary circumstances where a patient has experienced a significant
adverse reaction with two (2) lower-cost interchangeable drug products, where
available. When a prescriber identifies a patient for which it is medically necessary
that a higher cost interchangeable product be provided, the prescriber must:
• Complete, sign and forward to the pharmacist a copy of the Health Canada
side effect reporting form for each lower-cost interchangeable drug product
trialed (Side Effect Reporting Form[s]); and
• Write “No Substitution” or “No Sub” on a written prescription or indicate “No
Substitution” to the pharmacist in the case of a verbal prescription.
The prescriber should keep a copy of the completed form in the patient’s record for
future use and reference.
In the case of a written prescription, when the pharmacist or dispensing physician
receives a prescription with the written notation “No Substitution” or “No Sub”,
reimbursement will be provided for the higher-cost interchangeable product only if
the prescription is accompanied by a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed.
This form must be completely filled out noting the details of the adverse reaction
and signed by the prescriber.
In the case of a verbal prescription, the prescriber must satisfy the operator of the
pharmacy or dispensing physician that a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed
has been completed and signed by the prescriber. A written record of this verbal
prescription and the completed Health Canada Side Effect Reporting Form must be
received by the pharmacy prior to claim submission.
Upon receipt, the pharmacist must:
• Fax, submit online or mail the completed and signed form to Health Canada’s
Canada Vigilance Program; and
• Retain his or her copy of the completed and signed Side Effect Reporting
Form.
(ontario.ca, Revision #17; 2026-08-03 ↗)1 brand, same coverage
M-Venlafaxine XR · DIN 02471280
Manufacturer: Mantra Pharma Inc.; listing date 2021-11-30
Health Canada: Marketed since 2026-03-05 · brand M-VENLAFAXINE XR · ATC N06AX16 VENLAFAXINE · form Capsule (extended-release) · route Oral · ingredients VENLAFAXINE (VENLAFAXINE HYDROCHLORIDE) 37.5 MG · company Mantra pharma inc · schedule Prescription
Check this DIN again · Health Canada product recordM-Venlafaxine XR: Formulary list price $0.0913/unit (unit not stated in source; not the patient's cost)
Ministry pays: $0.0913 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=96039 · Verify on the e-Formulary ↗ (DIN 02471280)
Source record
DIN 02471280: M-Venlafaxine XR
Raw flags: sec3=Y
Item: 281604087; group id 474; item number 1193; lccId None; manufacturer id MAT
Source form: ER Cap; strength: 37.5mg
Recorded listing: General benefit
Source prices (unrounded): $0.0913; ministry $0.0913
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02471280
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=96039
Interchangeable products
ACT Venlafaxine XR · DIN 02304317 · $0.0913
Apo-Venlafaxine XR · DIN 02331683 · $0.0913
Auro-Venlafaxine XR · DIN 02452839 · $0.0913
Effexor XR · DIN 02237279 · $0.0913
Mint-Venlafaxine XR · DIN 02522977 · $0.0913
PMS-Venlafaxine XR · DIN 02278545 · $0.0913
PMSC-Venlafaxine XR · DIN 02521466 · $0.0913
Sandoz Venlafaxine XR · DIN 02310317 · $0.0913
Taro-Venlafaxine XR · DIN 02380072 · $0.0913
Teva-Venlafaxine XR · DIN 02275023 · $0.0913
Venlafaxine XR · DIN 02354713 · $0.0913
Venlafaxine XR · DIN 02385929 · $0.0913
Venlafaxine XR · DIN 02489678 · $0.0913
Venlafaxine XR · DIN 02516535 · $0.0913
Shortage status: no shortage or discontinuation reported (checked 2026-09-13T08:10:21.292534+00:00); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02471280
Shortage record checked 2026-09-13T08:10:21.292534+00:00
PMSC-Venlafaxine XR · DIN 02521466 · 37.5mg · extended release capsule
General benefitMarketed · checked 2026-09-02
Write on scriptno code needed
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Brand vs generic price
Lowest DBP recovery rule under medically necessary no-substitution claims:
6.2 Medically Necessary "No Substitution" Claims
The Side Effect Reporting Form will not have to be renewed. However, the
pharmacy must maintain a copy of the prescription that contains a direction that
there be no substitution and the required Health Canada Side Effect Reporting Form
(completed and signed by the prescriber). The prescriber must write “No
Substitution” or “No Sub” on renewal or subsequent new written prescriptions, and
indicate “No Substitution” on subsequent new oral prescriptions. The dispenser will
be reimbursed the DBP plus a mark-up and the lesser of the posted usual and
customary fee or the ODB dispensing fee minus the applicable ODB co-payment
amount. Where a completed Side Effect Reporting Form is not available at the
pharmacy during an inspection, the difference between the cost of the higher-cost
product and the lowest DBP listed for the interchangeable category will be
recovered.
(ontario.ca, Revision #17; 2026-08-03 ↗)
6.2 Medically Necessary "No Substitution" Claims
The Ministry will provide reimbursement of a higher-cost interchangeable product in
medically necessary circumstances where a patient has experienced a significant
adverse reaction with two (2) lower-cost interchangeable drug products, where
available. When a prescriber identifies a patient for which it is medically necessary
that a higher cost interchangeable product be provided, the prescriber must:
• Complete, sign and forward to the pharmacist a copy of the Health Canada
side effect reporting form for each lower-cost interchangeable drug product
trialed (Side Effect Reporting Form[s]); and
• Write “No Substitution” or “No Sub” on a written prescription or indicate “No
Substitution” to the pharmacist in the case of a verbal prescription.
The prescriber should keep a copy of the completed form in the patient’s record for
future use and reference.
In the case of a written prescription, when the pharmacist or dispensing physician
receives a prescription with the written notation “No Substitution” or “No Sub”,
reimbursement will be provided for the higher-cost interchangeable product only if
the prescription is accompanied by a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed.
This form must be completely filled out noting the details of the adverse reaction
and signed by the prescriber.
In the case of a verbal prescription, the prescriber must satisfy the operator of the
pharmacy or dispensing physician that a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed
has been completed and signed by the prescriber. A written record of this verbal
prescription and the completed Health Canada Side Effect Reporting Form must be
received by the pharmacy prior to claim submission.
Upon receipt, the pharmacist must:
• Fax, submit online or mail the completed and signed form to Health Canada’s
Canada Vigilance Program; and
• Retain his or her copy of the completed and signed Side Effect Reporting
Form.
(ontario.ca, Revision #17; 2026-08-03 ↗)1 brand, same coverage
PMSC-Venlafaxine XR · DIN 02521466
Manufacturer: Pharmascience Inc.; listing date 2022-11-30
Health Canada: Marketed since 2022-09-23 · brand PMSC-VENLAFAXINE XR · ATC N06AX16 VENLAFAXINE · form Capsule (extended-release) · route Oral · ingredients VENLAFAXINE (VENLAFAXINE HYDROCHLORIDE) 37.5 MG · company Pharmascience inc · schedule Prescription
Check this DIN again · Health Canada product recordPMSC-Venlafaxine XR: Formulary list price $0.0913/unit (unit not stated in source; not the patient's cost)
Ministry pays: $0.0913 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=101065 · Verify on the e-Formulary ↗ (DIN 02521466)
Source record
DIN 02521466: PMSC-Venlafaxine XR
Raw flags: sec3=Y
Item: 281604087; group id 474; item number 1193; lccId None; manufacturer id PMS
Source form: ER Cap; strength: 37.5mg
Recorded listing: General benefit
Source prices (unrounded): $0.0913; ministry $0.0913
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02521466
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=101065
Interchangeable products
ACT Venlafaxine XR · DIN 02304317 · $0.0913
Apo-Venlafaxine XR · DIN 02331683 · $0.0913
Auro-Venlafaxine XR · DIN 02452839 · $0.0913
Effexor XR · DIN 02237279 · $0.0913
M-Venlafaxine XR · DIN 02471280 · $0.0913
Mint-Venlafaxine XR · DIN 02522977 · $0.0913
PMS-Venlafaxine XR · DIN 02278545 · $0.0913
Sandoz Venlafaxine XR · DIN 02310317 · $0.0913
Taro-Venlafaxine XR · DIN 02380072 · $0.0913
Teva-Venlafaxine XR · DIN 02275023 · $0.0913
Venlafaxine XR · DIN 02354713 · $0.0913
Venlafaxine XR · DIN 02385929 · $0.0913
Venlafaxine XR · DIN 02489678 · $0.0913
Venlafaxine XR · DIN 02516535 · $0.0913
Shortage status: no shortage or discontinuation reported (checked 2026-09-13T08:10:21.292534+00:00); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02521466
Shortage record checked 2026-09-13T08:10:21.292534+00:00
Sandoz Venlafaxine XR · DIN 02310317 · 37.5mg · extended release capsule
General benefitMarketed · checked 2026-09-02
Write on scriptno code needed
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Brand vs generic price
Lowest DBP recovery rule under medically necessary no-substitution claims:
6.2 Medically Necessary "No Substitution" Claims
The Side Effect Reporting Form will not have to be renewed. However, the
pharmacy must maintain a copy of the prescription that contains a direction that
there be no substitution and the required Health Canada Side Effect Reporting Form
(completed and signed by the prescriber). The prescriber must write “No
Substitution” or “No Sub” on renewal or subsequent new written prescriptions, and
indicate “No Substitution” on subsequent new oral prescriptions. The dispenser will
be reimbursed the DBP plus a mark-up and the lesser of the posted usual and
customary fee or the ODB dispensing fee minus the applicable ODB co-payment
amount. Where a completed Side Effect Reporting Form is not available at the
pharmacy during an inspection, the difference between the cost of the higher-cost
product and the lowest DBP listed for the interchangeable category will be
recovered.
(ontario.ca, Revision #17; 2026-08-03 ↗)
6.2 Medically Necessary "No Substitution" Claims
The Ministry will provide reimbursement of a higher-cost interchangeable product in
medically necessary circumstances where a patient has experienced a significant
adverse reaction with two (2) lower-cost interchangeable drug products, where
available. When a prescriber identifies a patient for which it is medically necessary
that a higher cost interchangeable product be provided, the prescriber must:
• Complete, sign and forward to the pharmacist a copy of the Health Canada
side effect reporting form for each lower-cost interchangeable drug product
trialed (Side Effect Reporting Form[s]); and
• Write “No Substitution” or “No Sub” on a written prescription or indicate “No
Substitution” to the pharmacist in the case of a verbal prescription.
The prescriber should keep a copy of the completed form in the patient’s record for
future use and reference.
In the case of a written prescription, when the pharmacist or dispensing physician
receives a prescription with the written notation “No Substitution” or “No Sub”,
reimbursement will be provided for the higher-cost interchangeable product only if
the prescription is accompanied by a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed.
This form must be completely filled out noting the details of the adverse reaction
and signed by the prescriber.
In the case of a verbal prescription, the prescriber must satisfy the operator of the
pharmacy or dispensing physician that a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed
has been completed and signed by the prescriber. A written record of this verbal
prescription and the completed Health Canada Side Effect Reporting Form must be
received by the pharmacy prior to claim submission.
Upon receipt, the pharmacist must:
• Fax, submit online or mail the completed and signed form to Health Canada’s
Canada Vigilance Program; and
• Retain his or her copy of the completed and signed Side Effect Reporting
Form.
(ontario.ca, Revision #17; 2026-08-03 ↗)1 brand, same coverage
Sandoz Venlafaxine XR · DIN 02310317
Manufacturer: Sandoz Canada Inc.; listing date 2008-08-28
Health Canada: Marketed since 2020-03-20 · brand SANDOZ VENLAFAXINE XR · ATC N06AX16 VENLAFAXINE · form Capsule (extended-release) · route Oral · ingredients VENLAFAXINE (VENLAFAXINE HYDROCHLORIDE) 37.5 MG · company Sandoz canada incorporated · schedule Prescription
Check this DIN again · Health Canada product recordSandoz Venlafaxine XR: Formulary list price $0.0913/unit (unit not stated in source; not the patient's cost)
Ministry pays: $0.0913 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=79596 · Verify on the e-Formulary ↗ (DIN 02310317)
Source record
DIN 02310317: Sandoz Venlafaxine XR
Raw flags: sec3=Y
Item: 281604087; group id 474; item number 1193; lccId None; manufacturer id SDZ
Source form: ER Cap; strength: 37.5mg
Recorded listing: General benefit
Source prices (unrounded): $0.0913; ministry $0.0913
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02310317
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=79596
Interchangeable products
ACT Venlafaxine XR · DIN 02304317 · $0.0913
Apo-Venlafaxine XR · DIN 02331683 · $0.0913
Auro-Venlafaxine XR · DIN 02452839 · $0.0913
Effexor XR · DIN 02237279 · $0.0913
M-Venlafaxine XR · DIN 02471280 · $0.0913
Mint-Venlafaxine XR · DIN 02522977 · $0.0913
PMS-Venlafaxine XR · DIN 02278545 · $0.0913
PMSC-Venlafaxine XR · DIN 02521466 · $0.0913
Taro-Venlafaxine XR · DIN 02380072 · $0.0913
Teva-Venlafaxine XR · DIN 02275023 · $0.0913
Venlafaxine XR · DIN 02354713 · $0.0913
Venlafaxine XR · DIN 02385929 · $0.0913
Venlafaxine XR · DIN 02489678 · $0.0913
Venlafaxine XR · DIN 02516535 · $0.0913
Shortage status: resolved shortage (ended 2020-01-16); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02310317
Shortage record checked 2026-09-13T08:10:21.292534+00:00
Taro-Venlafaxine XR · DIN 02380072 · 37.5mg · extended release capsule
General benefitMarketed · checked 2026-09-02
Write on scriptno code needed
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Brand vs generic price
Lowest DBP recovery rule under medically necessary no-substitution claims:
6.2 Medically Necessary "No Substitution" Claims
The Side Effect Reporting Form will not have to be renewed. However, the
pharmacy must maintain a copy of the prescription that contains a direction that
there be no substitution and the required Health Canada Side Effect Reporting Form
(completed and signed by the prescriber). The prescriber must write “No
Substitution” or “No Sub” on renewal or subsequent new written prescriptions, and
indicate “No Substitution” on subsequent new oral prescriptions. The dispenser will
be reimbursed the DBP plus a mark-up and the lesser of the posted usual and
customary fee or the ODB dispensing fee minus the applicable ODB co-payment
amount. Where a completed Side Effect Reporting Form is not available at the
pharmacy during an inspection, the difference between the cost of the higher-cost
product and the lowest DBP listed for the interchangeable category will be
recovered.
(ontario.ca, Revision #17; 2026-08-03 ↗)
6.2 Medically Necessary "No Substitution" Claims
The Ministry will provide reimbursement of a higher-cost interchangeable product in
medically necessary circumstances where a patient has experienced a significant
adverse reaction with two (2) lower-cost interchangeable drug products, where
available. When a prescriber identifies a patient for which it is medically necessary
that a higher cost interchangeable product be provided, the prescriber must:
• Complete, sign and forward to the pharmacist a copy of the Health Canada
side effect reporting form for each lower-cost interchangeable drug product
trialed (Side Effect Reporting Form[s]); and
• Write “No Substitution” or “No Sub” on a written prescription or indicate “No
Substitution” to the pharmacist in the case of a verbal prescription.
The prescriber should keep a copy of the completed form in the patient’s record for
future use and reference.
In the case of a written prescription, when the pharmacist or dispensing physician
receives a prescription with the written notation “No Substitution” or “No Sub”,
reimbursement will be provided for the higher-cost interchangeable product only if
the prescription is accompanied by a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed.
This form must be completely filled out noting the details of the adverse reaction
and signed by the prescriber.
In the case of a verbal prescription, the prescriber must satisfy the operator of the
pharmacy or dispensing physician that a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed
has been completed and signed by the prescriber. A written record of this verbal
prescription and the completed Health Canada Side Effect Reporting Form must be
received by the pharmacy prior to claim submission.
Upon receipt, the pharmacist must:
• Fax, submit online or mail the completed and signed form to Health Canada’s
Canada Vigilance Program; and
• Retain his or her copy of the completed and signed Side Effect Reporting
Form.
(ontario.ca, Revision #17; 2026-08-03 ↗)1 brand, same coverage
Taro-Venlafaxine XR · DIN 02380072
Manufacturer: Sun Pharma; listing date 2012-04-24
Health Canada: Marketed since 2020-10-16 · brand TARO-VENLAFAXINE XR · ATC N06AX16 VENLAFAXINE · form Capsule (extended-release) · route Oral · ingredients VENLAFAXINE (VENLAFAXINE HYDROCHLORIDE) 37.5 MG · company Sun pharma canada inc · schedule Prescription
Check this DIN again · Health Canada product recordTaro-Venlafaxine XR: Formulary list price $0.0913/unit (unit not stated in source; not the patient's cost)
Ministry pays: $0.0913 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=86591 · Verify on the e-Formulary ↗ (DIN 02380072)
Source record
DIN 02380072: Taro-Venlafaxine XR
Raw flags: sec3=Y
Item: 281604087; group id 474; item number 1193; lccId None; manufacturer id SPC
Source form: ER Cap; strength: 37.5mg
Recorded listing: General benefit
Source prices (unrounded): $0.0913; ministry $0.0913
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02380072
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=86591
Interchangeable products
ACT Venlafaxine XR · DIN 02304317 · $0.0913
Apo-Venlafaxine XR · DIN 02331683 · $0.0913
Auro-Venlafaxine XR · DIN 02452839 · $0.0913
Effexor XR · DIN 02237279 · $0.0913
M-Venlafaxine XR · DIN 02471280 · $0.0913
Mint-Venlafaxine XR · DIN 02522977 · $0.0913
PMS-Venlafaxine XR · DIN 02278545 · $0.0913
PMSC-Venlafaxine XR · DIN 02521466 · $0.0913
Sandoz Venlafaxine XR · DIN 02310317 · $0.0913
Teva-Venlafaxine XR · DIN 02275023 · $0.0913
Venlafaxine XR · DIN 02354713 · $0.0913
Venlafaxine XR · DIN 02385929 · $0.0913
Venlafaxine XR · DIN 02489678 · $0.0913
Venlafaxine XR · DIN 02516535 · $0.0913
Shortage status: active shortage (reported 2026-05-19, estimated to end 2026-12-18, last updated 2026-09-04); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02380072
Shortage record checked 2026-09-13T08:10:21.292534+00:00
Venlafaxine XR · DIN 02354713 · 37.5mg · extended release capsule
General benefitMarketed · checked 2026-09-02
Write on scriptno code needed
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Brand vs generic price
Lowest DBP recovery rule under medically necessary no-substitution claims:
6.2 Medically Necessary "No Substitution" Claims
The Side Effect Reporting Form will not have to be renewed. However, the
pharmacy must maintain a copy of the prescription that contains a direction that
there be no substitution and the required Health Canada Side Effect Reporting Form
(completed and signed by the prescriber). The prescriber must write “No
Substitution” or “No Sub” on renewal or subsequent new written prescriptions, and
indicate “No Substitution” on subsequent new oral prescriptions. The dispenser will
be reimbursed the DBP plus a mark-up and the lesser of the posted usual and
customary fee or the ODB dispensing fee minus the applicable ODB co-payment
amount. Where a completed Side Effect Reporting Form is not available at the
pharmacy during an inspection, the difference between the cost of the higher-cost
product and the lowest DBP listed for the interchangeable category will be
recovered.
(ontario.ca, Revision #17; 2026-08-03 ↗)
6.2 Medically Necessary "No Substitution" Claims
The Ministry will provide reimbursement of a higher-cost interchangeable product in
medically necessary circumstances where a patient has experienced a significant
adverse reaction with two (2) lower-cost interchangeable drug products, where
available. When a prescriber identifies a patient for which it is medically necessary
that a higher cost interchangeable product be provided, the prescriber must:
• Complete, sign and forward to the pharmacist a copy of the Health Canada
side effect reporting form for each lower-cost interchangeable drug product
trialed (Side Effect Reporting Form[s]); and
• Write “No Substitution” or “No Sub” on a written prescription or indicate “No
Substitution” to the pharmacist in the case of a verbal prescription.
The prescriber should keep a copy of the completed form in the patient’s record for
future use and reference.
In the case of a written prescription, when the pharmacist or dispensing physician
receives a prescription with the written notation “No Substitution” or “No Sub”,
reimbursement will be provided for the higher-cost interchangeable product only if
the prescription is accompanied by a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed.
This form must be completely filled out noting the details of the adverse reaction
and signed by the prescriber.
In the case of a verbal prescription, the prescriber must satisfy the operator of the
pharmacy or dispensing physician that a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed
has been completed and signed by the prescriber. A written record of this verbal
prescription and the completed Health Canada Side Effect Reporting Form must be
received by the pharmacy prior to claim submission.
Upon receipt, the pharmacist must:
• Fax, submit online or mail the completed and signed form to Health Canada’s
Canada Vigilance Program; and
• Retain his or her copy of the completed and signed Side Effect Reporting
Form.
(ontario.ca, Revision #17; 2026-08-03 ↗)1 brand, same coverage
Venlafaxine XR · DIN 02354713
Manufacturer: Sanis Health Inc.; listing date 2011-08-04
Health Canada: Marketed since 2023-01-25 · brand VENLAFAXINE XR · ATC N06AX16 VENLAFAXINE · form Capsule (extended-release) · route Oral · ingredients VENLAFAXINE (VENLAFAXINE HYDROCHLORIDE) 37.5 MG · company Sanis health inc · schedule Prescription
Check this DIN again · Health Canada product recordVenlafaxine XR: Formulary list price $0.0913/unit (unit not stated in source; not the patient's cost)
Ministry pays: $0.0913 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=83988 · Verify on the e-Formulary ↗ (DIN 02354713)
Source record
DIN 02354713: Venlafaxine XR
Raw flags: sec3=Y
Item: 281604087; group id 474; item number 1193; lccId None; manufacturer id SAI
Source form: ER Cap; strength: 37.5mg
Recorded listing: General benefit
Source prices (unrounded): $0.0913; ministry $0.0913
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02354713
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=83988
Interchangeable products
ACT Venlafaxine XR · DIN 02304317 · $0.0913
Apo-Venlafaxine XR · DIN 02331683 · $0.0913
Auro-Venlafaxine XR · DIN 02452839 · $0.0913
Effexor XR · DIN 02237279 · $0.0913
M-Venlafaxine XR · DIN 02471280 · $0.0913
Mint-Venlafaxine XR · DIN 02522977 · $0.0913
PMS-Venlafaxine XR · DIN 02278545 · $0.0913
PMSC-Venlafaxine XR · DIN 02521466 · $0.0913
Sandoz Venlafaxine XR · DIN 02310317 · $0.0913
Taro-Venlafaxine XR · DIN 02380072 · $0.0913
Teva-Venlafaxine XR · DIN 02275023 · $0.0913
Venlafaxine XR · DIN 02385929 · $0.0913
Venlafaxine XR · DIN 02489678 · $0.0913
Venlafaxine XR · DIN 02516535 · $0.0913
Shortage status: resolved shortage (ended 2025-02-10); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02354713
Shortage record checked 2026-09-13T08:10:21.292534+00:00
Venlafaxine XR · DIN 02385929 · 37.5mg · extended release capsule
General benefitMarketed · checked 2026-09-02
Write on scriptno code needed
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Brand vs generic price
Lowest DBP recovery rule under medically necessary no-substitution claims:
6.2 Medically Necessary "No Substitution" Claims
The Side Effect Reporting Form will not have to be renewed. However, the
pharmacy must maintain a copy of the prescription that contains a direction that
there be no substitution and the required Health Canada Side Effect Reporting Form
(completed and signed by the prescriber). The prescriber must write “No
Substitution” or “No Sub” on renewal or subsequent new written prescriptions, and
indicate “No Substitution” on subsequent new oral prescriptions. The dispenser will
be reimbursed the DBP plus a mark-up and the lesser of the posted usual and
customary fee or the ODB dispensing fee minus the applicable ODB co-payment
amount. Where a completed Side Effect Reporting Form is not available at the
pharmacy during an inspection, the difference between the cost of the higher-cost
product and the lowest DBP listed for the interchangeable category will be
recovered.
(ontario.ca, Revision #17; 2026-08-03 ↗)
6.2 Medically Necessary "No Substitution" Claims
The Ministry will provide reimbursement of a higher-cost interchangeable product in
medically necessary circumstances where a patient has experienced a significant
adverse reaction with two (2) lower-cost interchangeable drug products, where
available. When a prescriber identifies a patient for which it is medically necessary
that a higher cost interchangeable product be provided, the prescriber must:
• Complete, sign and forward to the pharmacist a copy of the Health Canada
side effect reporting form for each lower-cost interchangeable drug product
trialed (Side Effect Reporting Form[s]); and
• Write “No Substitution” or “No Sub” on a written prescription or indicate “No
Substitution” to the pharmacist in the case of a verbal prescription.
The prescriber should keep a copy of the completed form in the patient’s record for
future use and reference.
In the case of a written prescription, when the pharmacist or dispensing physician
receives a prescription with the written notation “No Substitution” or “No Sub”,
reimbursement will be provided for the higher-cost interchangeable product only if
the prescription is accompanied by a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed.
This form must be completely filled out noting the details of the adverse reaction
and signed by the prescriber.
In the case of a verbal prescription, the prescriber must satisfy the operator of the
pharmacy or dispensing physician that a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed
has been completed and signed by the prescriber. A written record of this verbal
prescription and the completed Health Canada Side Effect Reporting Form must be
received by the pharmacy prior to claim submission.
Upon receipt, the pharmacist must:
• Fax, submit online or mail the completed and signed form to Health Canada’s
Canada Vigilance Program; and
• Retain his or her copy of the completed and signed Side Effect Reporting
Form.
(ontario.ca, Revision #17; 2026-08-03 ↗)1 brand, same coverage
Venlafaxine XR · DIN 02385929
Manufacturer: Sivem Pharmaceuticals ULC; listing date 2020-06-30
Health Canada: Marketed since 2018-06-08 · brand VENLAFAXINE XR · ATC N06AX16 VENLAFAXINE · form Capsule (extended-release) · route Oral · ingredients VENLAFAXINE (VENLAFAXINE HYDROCHLORIDE) 37.5 MG · company Sivem pharmaceuticals ulc · schedule Prescription
Check this DIN again · Health Canada product recordVenlafaxine XR: Formulary list price $0.0913/unit (unit not stated in source; not the patient's cost)
Ministry pays: $0.0913 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=87153 · Verify on the e-Formulary ↗ (DIN 02385929)
Source record
DIN 02385929: Venlafaxine XR
Raw flags: sec3=Y
Item: 281604087; group id 474; item number 1193; lccId None; manufacturer id SIV
Source form: ER Cap; strength: 37.5mg
Recorded listing: General benefit
Source prices (unrounded): $0.0913; ministry $0.0913
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02385929
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=87153
Interchangeable products
ACT Venlafaxine XR · DIN 02304317 · $0.0913
Apo-Venlafaxine XR · DIN 02331683 · $0.0913
Auro-Venlafaxine XR · DIN 02452839 · $0.0913
Effexor XR · DIN 02237279 · $0.0913
M-Venlafaxine XR · DIN 02471280 · $0.0913
Mint-Venlafaxine XR · DIN 02522977 · $0.0913
PMS-Venlafaxine XR · DIN 02278545 · $0.0913
PMSC-Venlafaxine XR · DIN 02521466 · $0.0913
Sandoz Venlafaxine XR · DIN 02310317 · $0.0913
Taro-Venlafaxine XR · DIN 02380072 · $0.0913
Teva-Venlafaxine XR · DIN 02275023 · $0.0913
Venlafaxine XR · DIN 02354713 · $0.0913
Venlafaxine XR · DIN 02489678 · $0.0913
Venlafaxine XR · DIN 02516535 · $0.0913
Shortage status: resolved shortage (ended 2018-07-02); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02385929
Shortage record checked 2026-09-13T08:10:21.292534+00:00
Venlafaxine XR · DIN 02489678 · 37.5mg · extended release capsule
General benefitMarketed · checked 2026-09-02
Write on scriptno code needed
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Brand vs generic price
Lowest DBP recovery rule under medically necessary no-substitution claims:
6.2 Medically Necessary "No Substitution" Claims
The Side Effect Reporting Form will not have to be renewed. However, the
pharmacy must maintain a copy of the prescription that contains a direction that
there be no substitution and the required Health Canada Side Effect Reporting Form
(completed and signed by the prescriber). The prescriber must write “No
Substitution” or “No Sub” on renewal or subsequent new written prescriptions, and
indicate “No Substitution” on subsequent new oral prescriptions. The dispenser will
be reimbursed the DBP plus a mark-up and the lesser of the posted usual and
customary fee or the ODB dispensing fee minus the applicable ODB co-payment
amount. Where a completed Side Effect Reporting Form is not available at the
pharmacy during an inspection, the difference between the cost of the higher-cost
product and the lowest DBP listed for the interchangeable category will be
recovered.
(ontario.ca, Revision #17; 2026-08-03 ↗)
6.2 Medically Necessary "No Substitution" Claims
The Ministry will provide reimbursement of a higher-cost interchangeable product in
medically necessary circumstances where a patient has experienced a significant
adverse reaction with two (2) lower-cost interchangeable drug products, where
available. When a prescriber identifies a patient for which it is medically necessary
that a higher cost interchangeable product be provided, the prescriber must:
• Complete, sign and forward to the pharmacist a copy of the Health Canada
side effect reporting form for each lower-cost interchangeable drug product
trialed (Side Effect Reporting Form[s]); and
• Write “No Substitution” or “No Sub” on a written prescription or indicate “No
Substitution” to the pharmacist in the case of a verbal prescription.
The prescriber should keep a copy of the completed form in the patient’s record for
future use and reference.
In the case of a written prescription, when the pharmacist or dispensing physician
receives a prescription with the written notation “No Substitution” or “No Sub”,
reimbursement will be provided for the higher-cost interchangeable product only if
the prescription is accompanied by a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed.
This form must be completely filled out noting the details of the adverse reaction
and signed by the prescriber.
In the case of a verbal prescription, the prescriber must satisfy the operator of the
pharmacy or dispensing physician that a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed
has been completed and signed by the prescriber. A written record of this verbal
prescription and the completed Health Canada Side Effect Reporting Form must be
received by the pharmacy prior to claim submission.
Upon receipt, the pharmacist must:
• Fax, submit online or mail the completed and signed form to Health Canada’s
Canada Vigilance Program; and
• Retain his or her copy of the completed and signed Side Effect Reporting
Form.
(ontario.ca, Revision #17; 2026-08-03 ↗)1 brand, same coverage
Venlafaxine XR · DIN 02489678
Manufacturer: Laboratoire Riva Inc.; listing date 2024-11-29
Health Canada: Marketed since 2019-08-07 · brand VENLAFAXINE XR · ATC N06AX16 VENLAFAXINE · form Capsule (extended-release) · route Oral · ingredients VENLAFAXINE (VENLAFAXINE HYDROCHLORIDE) 37.5 MG · company Laboratoire riva inc. · schedule Prescription
Check this DIN again · Health Canada product recordVenlafaxine XR: Formulary list price $0.0913/unit (unit not stated in source; not the patient's cost)
Ministry pays: $0.0913 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=97974 · Verify on the e-Formulary ↗ (DIN 02489678)
Source record
DIN 02489678: Venlafaxine XR
Raw flags: sec3=Y
Item: 281604087; group id 474; item number 1193; lccId None; manufacturer id RIA
Source form: ER Cap; strength: 37.5mg
Recorded listing: General benefit
Source prices (unrounded): $0.0913; ministry $0.0913
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02489678
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=97974
Interchangeable products
ACT Venlafaxine XR · DIN 02304317 · $0.0913
Apo-Venlafaxine XR · DIN 02331683 · $0.0913
Auro-Venlafaxine XR · DIN 02452839 · $0.0913
Effexor XR · DIN 02237279 · $0.0913
M-Venlafaxine XR · DIN 02471280 · $0.0913
Mint-Venlafaxine XR · DIN 02522977 · $0.0913
PMS-Venlafaxine XR · DIN 02278545 · $0.0913
PMSC-Venlafaxine XR · DIN 02521466 · $0.0913
Sandoz Venlafaxine XR · DIN 02310317 · $0.0913
Taro-Venlafaxine XR · DIN 02380072 · $0.0913
Teva-Venlafaxine XR · DIN 02275023 · $0.0913
Venlafaxine XR · DIN 02354713 · $0.0913
Venlafaxine XR · DIN 02385929 · $0.0913
Venlafaxine XR · DIN 02516535 · $0.0913
Shortage status: no shortage or discontinuation reported (checked 2026-09-13T08:10:21.292534+00:00); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02489678
Shortage record checked 2026-09-13T08:10:21.292534+00:00
Venlafaxine XR · DIN 02516535 · 37.5mg · extended release capsule
General benefitMarketed · checked 2026-09-02
Write on scriptno code needed
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Brand vs generic price
Lowest DBP recovery rule under medically necessary no-substitution claims:
6.2 Medically Necessary "No Substitution" Claims
The Side Effect Reporting Form will not have to be renewed. However, the
pharmacy must maintain a copy of the prescription that contains a direction that
there be no substitution and the required Health Canada Side Effect Reporting Form
(completed and signed by the prescriber). The prescriber must write “No
Substitution” or “No Sub” on renewal or subsequent new written prescriptions, and
indicate “No Substitution” on subsequent new oral prescriptions. The dispenser will
be reimbursed the DBP plus a mark-up and the lesser of the posted usual and
customary fee or the ODB dispensing fee minus the applicable ODB co-payment
amount. Where a completed Side Effect Reporting Form is not available at the
pharmacy during an inspection, the difference between the cost of the higher-cost
product and the lowest DBP listed for the interchangeable category will be
recovered.
(ontario.ca, Revision #17; 2026-08-03 ↗)
6.2 Medically Necessary "No Substitution" Claims
The Ministry will provide reimbursement of a higher-cost interchangeable product in
medically necessary circumstances where a patient has experienced a significant
adverse reaction with two (2) lower-cost interchangeable drug products, where
available. When a prescriber identifies a patient for which it is medically necessary
that a higher cost interchangeable product be provided, the prescriber must:
• Complete, sign and forward to the pharmacist a copy of the Health Canada
side effect reporting form for each lower-cost interchangeable drug product
trialed (Side Effect Reporting Form[s]); and
• Write “No Substitution” or “No Sub” on a written prescription or indicate “No
Substitution” to the pharmacist in the case of a verbal prescription.
The prescriber should keep a copy of the completed form in the patient’s record for
future use and reference.
In the case of a written prescription, when the pharmacist or dispensing physician
receives a prescription with the written notation “No Substitution” or “No Sub”,
reimbursement will be provided for the higher-cost interchangeable product only if
the prescription is accompanied by a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed.
This form must be completely filled out noting the details of the adverse reaction
and signed by the prescriber.
In the case of a verbal prescription, the prescriber must satisfy the operator of the
pharmacy or dispensing physician that a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed
has been completed and signed by the prescriber. A written record of this verbal
prescription and the completed Health Canada Side Effect Reporting Form must be
received by the pharmacy prior to claim submission.
Upon receipt, the pharmacist must:
• Fax, submit online or mail the completed and signed form to Health Canada’s
Canada Vigilance Program; and
• Retain his or her copy of the completed and signed Side Effect Reporting
Form.
(ontario.ca, Revision #17; 2026-08-03 ↗)1 brand, same coverage
Venlafaxine XR · DIN 02516535
Manufacturer: Jamp Pharma Corporation; listing date 2022-02-28
Health Canada: Marketed since 2021-12-29 · brand VENLAFAXINE XR · ATC N06AX16 VENLAFAXINE · form Capsule (extended-release) · route Oral · ingredients VENLAFAXINE (VENLAFAXINE HYDROCHLORIDE) 37.5 MG · company Jamp pharma corporation · schedule Prescription
Check this DIN again · Health Canada product recordVenlafaxine XR: Formulary list price $0.0913/unit (unit not stated in source; not the patient's cost)
Ministry pays: $0.0913 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=100588 · Verify on the e-Formulary ↗ (DIN 02516535)
Source record
DIN 02516535: Venlafaxine XR
Raw flags: sec3=Y
Item: 281604087; group id 474; item number 1193; lccId None; manufacturer id JPC
Source form: ER Cap; strength: 37.5mg
Recorded listing: General benefit
Source prices (unrounded): $0.0913; ministry $0.0913
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02516535
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=100588
Interchangeable products
ACT Venlafaxine XR · DIN 02304317 · $0.0913
Apo-Venlafaxine XR · DIN 02331683 · $0.0913
Auro-Venlafaxine XR · DIN 02452839 · $0.0913
Effexor XR · DIN 02237279 · $0.0913
M-Venlafaxine XR · DIN 02471280 · $0.0913
Mint-Venlafaxine XR · DIN 02522977 · $0.0913
PMS-Venlafaxine XR · DIN 02278545 · $0.0913
PMSC-Venlafaxine XR · DIN 02521466 · $0.0913
Sandoz Venlafaxine XR · DIN 02310317 · $0.0913
Taro-Venlafaxine XR · DIN 02380072 · $0.0913
Teva-Venlafaxine XR · DIN 02275023 · $0.0913
Venlafaxine XR · DIN 02354713 · $0.0913
Venlafaxine XR · DIN 02385929 · $0.0913
Venlafaxine XR · DIN 02489678 · $0.0913
Shortage status: resolved shortage (ended 2025-03-17); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02516535
Shortage record checked 2026-09-13T08:10:21.292534+00:00
ACT Venlafaxine XR · DIN 02304325 · 75mg · extended release capsule
General benefitMarketed · checked 2026-09-02
Write on scriptno code needed
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Brand vs generic price
Lowest DBP recovery rule under medically necessary no-substitution claims:
6.2 Medically Necessary "No Substitution" Claims
The Side Effect Reporting Form will not have to be renewed. However, the
pharmacy must maintain a copy of the prescription that contains a direction that
there be no substitution and the required Health Canada Side Effect Reporting Form
(completed and signed by the prescriber). The prescriber must write “No
Substitution” or “No Sub” on renewal or subsequent new written prescriptions, and
indicate “No Substitution” on subsequent new oral prescriptions. The dispenser will
be reimbursed the DBP plus a mark-up and the lesser of the posted usual and
customary fee or the ODB dispensing fee minus the applicable ODB co-payment
amount. Where a completed Side Effect Reporting Form is not available at the
pharmacy during an inspection, the difference between the cost of the higher-cost
product and the lowest DBP listed for the interchangeable category will be
recovered.
(ontario.ca, Revision #17; 2026-08-03 ↗)
6.2 Medically Necessary "No Substitution" Claims
The Ministry will provide reimbursement of a higher-cost interchangeable product in
medically necessary circumstances where a patient has experienced a significant
adverse reaction with two (2) lower-cost interchangeable drug products, where
available. When a prescriber identifies a patient for which it is medically necessary
that a higher cost interchangeable product be provided, the prescriber must:
• Complete, sign and forward to the pharmacist a copy of the Health Canada
side effect reporting form for each lower-cost interchangeable drug product
trialed (Side Effect Reporting Form[s]); and
• Write “No Substitution” or “No Sub” on a written prescription or indicate “No
Substitution” to the pharmacist in the case of a verbal prescription.
The prescriber should keep a copy of the completed form in the patient’s record for
future use and reference.
In the case of a written prescription, when the pharmacist or dispensing physician
receives a prescription with the written notation “No Substitution” or “No Sub”,
reimbursement will be provided for the higher-cost interchangeable product only if
the prescription is accompanied by a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed.
This form must be completely filled out noting the details of the adverse reaction
and signed by the prescriber.
In the case of a verbal prescription, the prescriber must satisfy the operator of the
pharmacy or dispensing physician that a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed
has been completed and signed by the prescriber. A written record of this verbal
prescription and the completed Health Canada Side Effect Reporting Form must be
received by the pharmacy prior to claim submission.
Upon receipt, the pharmacist must:
• Fax, submit online or mail the completed and signed form to Health Canada’s
Canada Vigilance Program; and
• Retain his or her copy of the completed and signed Side Effect Reporting
Form.
(ontario.ca, Revision #17; 2026-08-03 ↗)1 brand, same coverage
ACT Venlafaxine XR · DIN 02304325
Manufacturer: Teva Canada Limited; listing date 2008-04-09
Health Canada: Marketed since 2019-03-01 · brand ACT VENLAFAXINE XR · ATC N06AX16 VENLAFAXINE · form Capsule (extended-release) · route Oral · ingredients VENLAFAXINE (VENLAFAXINE HYDROCHLORIDE) 75 MG · company Teva canada limited · schedule Prescription
Check this DIN again · Health Canada product recordACT Venlafaxine XR: Formulary list price $0.1825/unit (unit not stated in source; not the patient's cost)
Ministry pays: $0.1825 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=78961 · Verify on the e-Formulary ↗ (DIN 02304325)
Source record
DIN 02304325: ACT Venlafaxine XR
Raw flags: sec3=Y
Item: 281604088; group id 474; item number 1194; lccId None; manufacturer id TEV
Source form: ER Cap; strength: 75mg
Recorded listing: General benefit
Source prices (unrounded): $0.1825; ministry $0.1825
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02304325
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=78961
Interchangeable products
Apo-Venlafaxine XR · DIN 02331691 · $0.1825
Auro-Venlafaxine XR · DIN 02452847 · $0.1825
Effexor XR · DIN 02237280 · $0.1825
M-Venlafaxine XR · DIN 02471299 · $0.1825
Mint-Venlafaxine XR · DIN 02522985 · $0.1825
PMS-Venlafaxine XR · DIN 02278553 · $0.1825
PMSC-Venlafaxine XR · DIN 02521482 · $0.1825
Sandoz Venlafaxine XR · DIN 02310325 · $0.1825
Taro-Venlafaxine XR · DIN 02380080 · $0.1825
Teva-Venlafaxine XR · DIN 02275031 · $0.1825
Venlafaxine XR · DIN 02354721 · $0.1825
Venlafaxine XR · DIN 02385937 · $0.1825
Venlafaxine XR · DIN 02489686 · $0.1825
Venlafaxine XR · DIN 02516543 · $0.1825
Shortage status: active shortage (reported 2026-03-10, estimated to end 2026-08-20, last updated 2026-07-31); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02304325
Shortage record checked 2026-09-13T08:10:21.292534+00:00
Auro-Venlafaxine XR · DIN 02452847 · 75mg · extended release capsule
General benefitMarketed · checked 2026-09-02
Write on scriptno code needed
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Brand vs generic price
Lowest DBP recovery rule under medically necessary no-substitution claims:
6.2 Medically Necessary "No Substitution" Claims
The Side Effect Reporting Form will not have to be renewed. However, the
pharmacy must maintain a copy of the prescription that contains a direction that
there be no substitution and the required Health Canada Side Effect Reporting Form
(completed and signed by the prescriber). The prescriber must write “No
Substitution” or “No Sub” on renewal or subsequent new written prescriptions, and
indicate “No Substitution” on subsequent new oral prescriptions. The dispenser will
be reimbursed the DBP plus a mark-up and the lesser of the posted usual and
customary fee or the ODB dispensing fee minus the applicable ODB co-payment
amount. Where a completed Side Effect Reporting Form is not available at the
pharmacy during an inspection, the difference between the cost of the higher-cost
product and the lowest DBP listed for the interchangeable category will be
recovered.
(ontario.ca, Revision #17; 2026-08-03 ↗)
6.2 Medically Necessary "No Substitution" Claims
The Ministry will provide reimbursement of a higher-cost interchangeable product in
medically necessary circumstances where a patient has experienced a significant
adverse reaction with two (2) lower-cost interchangeable drug products, where
available. When a prescriber identifies a patient for which it is medically necessary
that a higher cost interchangeable product be provided, the prescriber must:
• Complete, sign and forward to the pharmacist a copy of the Health Canada
side effect reporting form for each lower-cost interchangeable drug product
trialed (Side Effect Reporting Form[s]); and
• Write “No Substitution” or “No Sub” on a written prescription or indicate “No
Substitution” to the pharmacist in the case of a verbal prescription.
The prescriber should keep a copy of the completed form in the patient’s record for
future use and reference.
In the case of a written prescription, when the pharmacist or dispensing physician
receives a prescription with the written notation “No Substitution” or “No Sub”,
reimbursement will be provided for the higher-cost interchangeable product only if
the prescription is accompanied by a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed.
This form must be completely filled out noting the details of the adverse reaction
and signed by the prescriber.
In the case of a verbal prescription, the prescriber must satisfy the operator of the
pharmacy or dispensing physician that a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed
has been completed and signed by the prescriber. A written record of this verbal
prescription and the completed Health Canada Side Effect Reporting Form must be
received by the pharmacy prior to claim submission.
Upon receipt, the pharmacist must:
• Fax, submit online or mail the completed and signed form to Health Canada’s
Canada Vigilance Program; and
• Retain his or her copy of the completed and signed Side Effect Reporting
Form.
(ontario.ca, Revision #17; 2026-08-03 ↗)1 brand, same coverage
Auro-Venlafaxine XR · DIN 02452847
Manufacturer: Auro Pharma Inc.; listing date 2016-05-31
Health Canada: Marketed since 2016-03-14 · brand AURO-VENLAFAXINE XR · ATC N06AX16 VENLAFAXINE · form Capsule (extended-release) · route Oral · ingredients VENLAFAXINE (VENLAFAXINE HYDROCHLORIDE) 75 MG · company Auro pharma inc · schedule Prescription
Check this DIN again · Health Canada product recordAuro-Venlafaxine XR: Formulary list price $0.1825/unit (unit not stated in source; not the patient's cost)
Ministry pays: $0.1825 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=93925 · Verify on the e-Formulary ↗ (DIN 02452847)
Source record
DIN 02452847: Auro-Venlafaxine XR
Raw flags: sec3=Y
Item: 281604088; group id 474; item number 1194; lccId None; manufacturer id AUR
Source form: ER Cap; strength: 75mg
Recorded listing: General benefit
Source prices (unrounded): $0.1825; ministry $0.1825
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02452847
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=93925
Interchangeable products
ACT Venlafaxine XR · DIN 02304325 · $0.1825
Apo-Venlafaxine XR · DIN 02331691 · $0.1825
Effexor XR · DIN 02237280 · $0.1825
M-Venlafaxine XR · DIN 02471299 · $0.1825
Mint-Venlafaxine XR · DIN 02522985 · $0.1825
PMS-Venlafaxine XR · DIN 02278553 · $0.1825
PMSC-Venlafaxine XR · DIN 02521482 · $0.1825
Sandoz Venlafaxine XR · DIN 02310325 · $0.1825
Taro-Venlafaxine XR · DIN 02380080 · $0.1825
Teva-Venlafaxine XR · DIN 02275031 · $0.1825
Venlafaxine XR · DIN 02354721 · $0.1825
Venlafaxine XR · DIN 02385937 · $0.1825
Venlafaxine XR · DIN 02489686 · $0.1825
Venlafaxine XR · DIN 02516543 · $0.1825
Shortage status: resolved shortage (ended 2019-08-15); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02452847
Shortage record checked 2026-09-13T08:10:21.292534+00:00
Effexor XR · DIN 02237280 · 75mg · extended release capsule
General benefitMarketed · checked 2026-09-02
Write on scriptno code needed
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Savings card: RxHelp ONE lists Effexor XR (read 2026-09-10) — brand-name savings card, free; cannot be combined with another card on the same claim.
(rxhelp.ca ↗)1 brand, same coverage
Effexor XR · DIN 02237280
Manufacturer: Upjohn Canada ULC; listing date 2000-01-17
Health Canada: Marketed since 2023-08-09 · brand EFFEXOR XR · ATC N06AX16 VENLAFAXINE · form Capsule (extended-release) · route Oral · ingredients VENLAFAXINE (VENLAFAXINE HYDROCHLORIDE) 75 MG · company Bgp pharma ulc · schedule Prescription
Check this DIN again · Health Canada product recordMinistry pays: $0.1825 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=60601 · Verify on the e-Formulary ↗ (DIN 02237280)
Source record
DIN 02237280: Effexor XR
Raw flags: sec3=Y
Item: 281604088; group id 474; item number 1194; lccId None; manufacturer id UJC
Source form: ER Cap; strength: 75mg
Recorded listing: General benefit
Source prices (unrounded): $2.3242; ministry $0.1825
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02237280
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=60601
Interchangeable products
ACT Venlafaxine XR · DIN 02304325 · $0.1825
Apo-Venlafaxine XR · DIN 02331691 · $0.1825
Auro-Venlafaxine XR · DIN 02452847 · $0.1825
M-Venlafaxine XR · DIN 02471299 · $0.1825
Mint-Venlafaxine XR · DIN 02522985 · $0.1825
PMS-Venlafaxine XR · DIN 02278553 · $0.1825
PMSC-Venlafaxine XR · DIN 02521482 · $0.1825
Sandoz Venlafaxine XR · DIN 02310325 · $0.1825
Taro-Venlafaxine XR · DIN 02380080 · $0.1825
Teva-Venlafaxine XR · DIN 02275031 · $0.1825
Venlafaxine XR · DIN 02354721 · $0.1825
Venlafaxine XR · DIN 02385937 · $0.1825
Venlafaxine XR · DIN 02489686 · $0.1825
Venlafaxine XR · DIN 02516543 · $0.1825
Shortage status: resolved shortage (ended 2018-01-19); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02237280
Shortage record checked 2026-09-13T08:10:21.292534+00:00
M-Venlafaxine XR · DIN 02471299 · 75mg · extended release capsule
General benefitMarketed · checked 2026-09-02
Write on scriptno code needed
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Brand vs generic price
Lowest DBP recovery rule under medically necessary no-substitution claims:
6.2 Medically Necessary "No Substitution" Claims
The Side Effect Reporting Form will not have to be renewed. However, the
pharmacy must maintain a copy of the prescription that contains a direction that
there be no substitution and the required Health Canada Side Effect Reporting Form
(completed and signed by the prescriber). The prescriber must write “No
Substitution” or “No Sub” on renewal or subsequent new written prescriptions, and
indicate “No Substitution” on subsequent new oral prescriptions. The dispenser will
be reimbursed the DBP plus a mark-up and the lesser of the posted usual and
customary fee or the ODB dispensing fee minus the applicable ODB co-payment
amount. Where a completed Side Effect Reporting Form is not available at the
pharmacy during an inspection, the difference between the cost of the higher-cost
product and the lowest DBP listed for the interchangeable category will be
recovered.
(ontario.ca, Revision #17; 2026-08-03 ↗)
6.2 Medically Necessary "No Substitution" Claims
The Ministry will provide reimbursement of a higher-cost interchangeable product in
medically necessary circumstances where a patient has experienced a significant
adverse reaction with two (2) lower-cost interchangeable drug products, where
available. When a prescriber identifies a patient for which it is medically necessary
that a higher cost interchangeable product be provided, the prescriber must:
• Complete, sign and forward to the pharmacist a copy of the Health Canada
side effect reporting form for each lower-cost interchangeable drug product
trialed (Side Effect Reporting Form[s]); and
• Write “No Substitution” or “No Sub” on a written prescription or indicate “No
Substitution” to the pharmacist in the case of a verbal prescription.
The prescriber should keep a copy of the completed form in the patient’s record for
future use and reference.
In the case of a written prescription, when the pharmacist or dispensing physician
receives a prescription with the written notation “No Substitution” or “No Sub”,
reimbursement will be provided for the higher-cost interchangeable product only if
the prescription is accompanied by a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed.
This form must be completely filled out noting the details of the adverse reaction
and signed by the prescriber.
In the case of a verbal prescription, the prescriber must satisfy the operator of the
pharmacy or dispensing physician that a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed
has been completed and signed by the prescriber. A written record of this verbal
prescription and the completed Health Canada Side Effect Reporting Form must be
received by the pharmacy prior to claim submission.
Upon receipt, the pharmacist must:
• Fax, submit online or mail the completed and signed form to Health Canada’s
Canada Vigilance Program; and
• Retain his or her copy of the completed and signed Side Effect Reporting
Form.
(ontario.ca, Revision #17; 2026-08-03 ↗)1 brand, same coverage
M-Venlafaxine XR · DIN 02471299
Manufacturer: Mantra Pharma Inc.; listing date 2021-11-30
Health Canada: Marketed since 2026-03-05 · brand M-VENLAFAXINE XR · ATC N06AX16 VENLAFAXINE · form Capsule (extended-release) · route Oral · ingredients VENLAFAXINE (VENLAFAXINE HYDROCHLORIDE) 75 MG · company Mantra pharma inc · schedule Prescription
Check this DIN again · Health Canada product recordM-Venlafaxine XR: Formulary list price $0.1825/unit (unit not stated in source; not the patient's cost)
Ministry pays: $0.1825 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=96040 · Verify on the e-Formulary ↗ (DIN 02471299)
Source record
DIN 02471299: M-Venlafaxine XR
Raw flags: sec3=Y
Item: 281604088; group id 474; item number 1194; lccId None; manufacturer id MAT
Source form: ER Cap; strength: 75mg
Recorded listing: General benefit
Source prices (unrounded): $0.1825; ministry $0.1825
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02471299
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=96040
Interchangeable products
ACT Venlafaxine XR · DIN 02304325 · $0.1825
Apo-Venlafaxine XR · DIN 02331691 · $0.1825
Auro-Venlafaxine XR · DIN 02452847 · $0.1825
Effexor XR · DIN 02237280 · $0.1825
Mint-Venlafaxine XR · DIN 02522985 · $0.1825
PMS-Venlafaxine XR · DIN 02278553 · $0.1825
PMSC-Venlafaxine XR · DIN 02521482 · $0.1825
Sandoz Venlafaxine XR · DIN 02310325 · $0.1825
Taro-Venlafaxine XR · DIN 02380080 · $0.1825
Teva-Venlafaxine XR · DIN 02275031 · $0.1825
Venlafaxine XR · DIN 02354721 · $0.1825
Venlafaxine XR · DIN 02385937 · $0.1825
Venlafaxine XR · DIN 02489686 · $0.1825
Venlafaxine XR · DIN 02516543 · $0.1825
Shortage status: no shortage or discontinuation reported (checked 2026-09-13T08:10:21.292534+00:00); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02471299
Shortage record checked 2026-09-13T08:10:21.292534+00:00
PMSC-Venlafaxine XR · DIN 02521482 · 75mg · extended release capsule
General benefitMarketed · checked 2026-09-02
Write on scriptno code needed
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Brand vs generic price
Lowest DBP recovery rule under medically necessary no-substitution claims:
6.2 Medically Necessary "No Substitution" Claims
The Side Effect Reporting Form will not have to be renewed. However, the
pharmacy must maintain a copy of the prescription that contains a direction that
there be no substitution and the required Health Canada Side Effect Reporting Form
(completed and signed by the prescriber). The prescriber must write “No
Substitution” or “No Sub” on renewal or subsequent new written prescriptions, and
indicate “No Substitution” on subsequent new oral prescriptions. The dispenser will
be reimbursed the DBP plus a mark-up and the lesser of the posted usual and
customary fee or the ODB dispensing fee minus the applicable ODB co-payment
amount. Where a completed Side Effect Reporting Form is not available at the
pharmacy during an inspection, the difference between the cost of the higher-cost
product and the lowest DBP listed for the interchangeable category will be
recovered.
(ontario.ca, Revision #17; 2026-08-03 ↗)
6.2 Medically Necessary "No Substitution" Claims
The Ministry will provide reimbursement of a higher-cost interchangeable product in
medically necessary circumstances where a patient has experienced a significant
adverse reaction with two (2) lower-cost interchangeable drug products, where
available. When a prescriber identifies a patient for which it is medically necessary
that a higher cost interchangeable product be provided, the prescriber must:
• Complete, sign and forward to the pharmacist a copy of the Health Canada
side effect reporting form for each lower-cost interchangeable drug product
trialed (Side Effect Reporting Form[s]); and
• Write “No Substitution” or “No Sub” on a written prescription or indicate “No
Substitution” to the pharmacist in the case of a verbal prescription.
The prescriber should keep a copy of the completed form in the patient’s record for
future use and reference.
In the case of a written prescription, when the pharmacist or dispensing physician
receives a prescription with the written notation “No Substitution” or “No Sub”,
reimbursement will be provided for the higher-cost interchangeable product only if
the prescription is accompanied by a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed.
This form must be completely filled out noting the details of the adverse reaction
and signed by the prescriber.
In the case of a verbal prescription, the prescriber must satisfy the operator of the
pharmacy or dispensing physician that a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed
has been completed and signed by the prescriber. A written record of this verbal
prescription and the completed Health Canada Side Effect Reporting Form must be
received by the pharmacy prior to claim submission.
Upon receipt, the pharmacist must:
• Fax, submit online or mail the completed and signed form to Health Canada’s
Canada Vigilance Program; and
• Retain his or her copy of the completed and signed Side Effect Reporting
Form.
(ontario.ca, Revision #17; 2026-08-03 ↗)1 brand, same coverage
PMSC-Venlafaxine XR · DIN 02521482
Manufacturer: Pharmascience Inc.; listing date 2022-10-31
Health Canada: Marketed since 2022-08-30 · brand PMSC-VENLAFAXINE XR · ATC N06AX16 VENLAFAXINE · form Capsule (extended-release) · route Oral · ingredients VENLAFAXINE (VENLAFAXINE HYDROCHLORIDE) 75 MG · company Pharmascience inc · schedule Prescription
Check this DIN again · Health Canada product recordPMSC-Venlafaxine XR: Formulary list price $0.1825/unit (unit not stated in source; not the patient's cost)
Ministry pays: $0.1825 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=101067 · Verify on the e-Formulary ↗ (DIN 02521482)
Source record
DIN 02521482: PMSC-Venlafaxine XR
Raw flags: sec3=Y
Item: 281604088; group id 474; item number 1194; lccId None; manufacturer id PMS
Source form: ER Cap; strength: 75mg
Recorded listing: General benefit
Source prices (unrounded): $0.1825; ministry $0.1825
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02521482
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=101067
Interchangeable products
ACT Venlafaxine XR · DIN 02304325 · $0.1825
Apo-Venlafaxine XR · DIN 02331691 · $0.1825
Auro-Venlafaxine XR · DIN 02452847 · $0.1825
Effexor XR · DIN 02237280 · $0.1825
M-Venlafaxine XR · DIN 02471299 · $0.1825
Mint-Venlafaxine XR · DIN 02522985 · $0.1825
PMS-Venlafaxine XR · DIN 02278553 · $0.1825
Sandoz Venlafaxine XR · DIN 02310325 · $0.1825
Taro-Venlafaxine XR · DIN 02380080 · $0.1825
Teva-Venlafaxine XR · DIN 02275031 · $0.1825
Venlafaxine XR · DIN 02354721 · $0.1825
Venlafaxine XR · DIN 02385937 · $0.1825
Venlafaxine XR · DIN 02489686 · $0.1825
Venlafaxine XR · DIN 02516543 · $0.1825
Shortage status: no shortage or discontinuation reported (checked 2026-09-13T08:10:21.292534+00:00); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02521482
Shortage record checked 2026-09-13T08:10:21.292534+00:00
Sandoz Venlafaxine XR · DIN 02310325 · 75mg · extended release capsule
General benefitMarketed · checked 2026-09-02
Write on scriptno code needed
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Brand vs generic price
Lowest DBP recovery rule under medically necessary no-substitution claims:
6.2 Medically Necessary "No Substitution" Claims
The Side Effect Reporting Form will not have to be renewed. However, the
pharmacy must maintain a copy of the prescription that contains a direction that
there be no substitution and the required Health Canada Side Effect Reporting Form
(completed and signed by the prescriber). The prescriber must write “No
Substitution” or “No Sub” on renewal or subsequent new written prescriptions, and
indicate “No Substitution” on subsequent new oral prescriptions. The dispenser will
be reimbursed the DBP plus a mark-up and the lesser of the posted usual and
customary fee or the ODB dispensing fee minus the applicable ODB co-payment
amount. Where a completed Side Effect Reporting Form is not available at the
pharmacy during an inspection, the difference between the cost of the higher-cost
product and the lowest DBP listed for the interchangeable category will be
recovered.
(ontario.ca, Revision #17; 2026-08-03 ↗)
6.2 Medically Necessary "No Substitution" Claims
The Ministry will provide reimbursement of a higher-cost interchangeable product in
medically necessary circumstances where a patient has experienced a significant
adverse reaction with two (2) lower-cost interchangeable drug products, where
available. When a prescriber identifies a patient for which it is medically necessary
that a higher cost interchangeable product be provided, the prescriber must:
• Complete, sign and forward to the pharmacist a copy of the Health Canada
side effect reporting form for each lower-cost interchangeable drug product
trialed (Side Effect Reporting Form[s]); and
• Write “No Substitution” or “No Sub” on a written prescription or indicate “No
Substitution” to the pharmacist in the case of a verbal prescription.
The prescriber should keep a copy of the completed form in the patient’s record for
future use and reference.
In the case of a written prescription, when the pharmacist or dispensing physician
receives a prescription with the written notation “No Substitution” or “No Sub”,
reimbursement will be provided for the higher-cost interchangeable product only if
the prescription is accompanied by a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed.
This form must be completely filled out noting the details of the adverse reaction
and signed by the prescriber.
In the case of a verbal prescription, the prescriber must satisfy the operator of the
pharmacy or dispensing physician that a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed
has been completed and signed by the prescriber. A written record of this verbal
prescription and the completed Health Canada Side Effect Reporting Form must be
received by the pharmacy prior to claim submission.
Upon receipt, the pharmacist must:
• Fax, submit online or mail the completed and signed form to Health Canada’s
Canada Vigilance Program; and
• Retain his or her copy of the completed and signed Side Effect Reporting
Form.
(ontario.ca, Revision #17; 2026-08-03 ↗)1 brand, same coverage
Sandoz Venlafaxine XR · DIN 02310325
Manufacturer: Sandoz Canada Inc.; listing date 2008-08-28
Health Canada: Marketed since 2020-03-20 · brand SANDOZ VENLAFAXINE XR · ATC N06AX16 VENLAFAXINE · form Capsule (extended-release) · route Oral · ingredients VENLAFAXINE (VENLAFAXINE HYDROCHLORIDE) 75 MG · company Sandoz canada incorporated · schedule Prescription
Check this DIN again · Health Canada product recordSandoz Venlafaxine XR: Formulary list price $0.1825/unit (unit not stated in source; not the patient's cost)
Ministry pays: $0.1825 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=79597 · Verify on the e-Formulary ↗ (DIN 02310325)
Source record
DIN 02310325: Sandoz Venlafaxine XR
Raw flags: sec3=Y
Item: 281604088; group id 474; item number 1194; lccId None; manufacturer id SDZ
Source form: ER Cap; strength: 75mg
Recorded listing: General benefit
Source prices (unrounded): $0.1825; ministry $0.1825
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02310325
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=79597
Interchangeable products
ACT Venlafaxine XR · DIN 02304325 · $0.1825
Apo-Venlafaxine XR · DIN 02331691 · $0.1825
Auro-Venlafaxine XR · DIN 02452847 · $0.1825
Effexor XR · DIN 02237280 · $0.1825
M-Venlafaxine XR · DIN 02471299 · $0.1825
Mint-Venlafaxine XR · DIN 02522985 · $0.1825
PMS-Venlafaxine XR · DIN 02278553 · $0.1825
PMSC-Venlafaxine XR · DIN 02521482 · $0.1825
Taro-Venlafaxine XR · DIN 02380080 · $0.1825
Teva-Venlafaxine XR · DIN 02275031 · $0.1825
Venlafaxine XR · DIN 02354721 · $0.1825
Venlafaxine XR · DIN 02385937 · $0.1825
Venlafaxine XR · DIN 02489686 · $0.1825
Venlafaxine XR · DIN 02516543 · $0.1825
Shortage status: shortage reported ended 2026-09-08 (report last updated 2026-09-08); confirm supply with the pharmacy; reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02310325
Shortage record checked 2026-09-13T08:10:21.292534+00:00
Taro-Venlafaxine XR · DIN 02380080 · 75mg · extended release capsule
General benefitMarketed · checked 2026-09-02
Write on scriptno code needed
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Brand vs generic price
Lowest DBP recovery rule under medically necessary no-substitution claims:
6.2 Medically Necessary "No Substitution" Claims
The Side Effect Reporting Form will not have to be renewed. However, the
pharmacy must maintain a copy of the prescription that contains a direction that
there be no substitution and the required Health Canada Side Effect Reporting Form
(completed and signed by the prescriber). The prescriber must write “No
Substitution” or “No Sub” on renewal or subsequent new written prescriptions, and
indicate “No Substitution” on subsequent new oral prescriptions. The dispenser will
be reimbursed the DBP plus a mark-up and the lesser of the posted usual and
customary fee or the ODB dispensing fee minus the applicable ODB co-payment
amount. Where a completed Side Effect Reporting Form is not available at the
pharmacy during an inspection, the difference between the cost of the higher-cost
product and the lowest DBP listed for the interchangeable category will be
recovered.
(ontario.ca, Revision #17; 2026-08-03 ↗)
6.2 Medically Necessary "No Substitution" Claims
The Ministry will provide reimbursement of a higher-cost interchangeable product in
medically necessary circumstances where a patient has experienced a significant
adverse reaction with two (2) lower-cost interchangeable drug products, where
available. When a prescriber identifies a patient for which it is medically necessary
that a higher cost interchangeable product be provided, the prescriber must:
• Complete, sign and forward to the pharmacist a copy of the Health Canada
side effect reporting form for each lower-cost interchangeable drug product
trialed (Side Effect Reporting Form[s]); and
• Write “No Substitution” or “No Sub” on a written prescription or indicate “No
Substitution” to the pharmacist in the case of a verbal prescription.
The prescriber should keep a copy of the completed form in the patient’s record for
future use and reference.
In the case of a written prescription, when the pharmacist or dispensing physician
receives a prescription with the written notation “No Substitution” or “No Sub”,
reimbursement will be provided for the higher-cost interchangeable product only if
the prescription is accompanied by a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed.
This form must be completely filled out noting the details of the adverse reaction
and signed by the prescriber.
In the case of a verbal prescription, the prescriber must satisfy the operator of the
pharmacy or dispensing physician that a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed
has been completed and signed by the prescriber. A written record of this verbal
prescription and the completed Health Canada Side Effect Reporting Form must be
received by the pharmacy prior to claim submission.
Upon receipt, the pharmacist must:
• Fax, submit online or mail the completed and signed form to Health Canada’s
Canada Vigilance Program; and
• Retain his or her copy of the completed and signed Side Effect Reporting
Form.
(ontario.ca, Revision #17; 2026-08-03 ↗)1 brand, same coverage
Taro-Venlafaxine XR · DIN 02380080
Manufacturer: Sun Pharma; listing date 2012-04-24
Health Canada: Marketed since 2020-10-16 · brand TARO-VENLAFAXINE XR · ATC N06AX16 VENLAFAXINE · form Capsule (extended-release) · route Oral · ingredients VENLAFAXINE (VENLAFAXINE HYDROCHLORIDE) 75 MG · company Sun pharma canada inc · schedule Prescription
Check this DIN again · Health Canada product recordTaro-Venlafaxine XR: Formulary list price $0.1825/unit (unit not stated in source; not the patient's cost)
Ministry pays: $0.1825 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=86592 · Verify on the e-Formulary ↗ (DIN 02380080)
Source record
DIN 02380080: Taro-Venlafaxine XR
Raw flags: sec3=Y
Item: 281604088; group id 474; item number 1194; lccId None; manufacturer id SPC
Source form: ER Cap; strength: 75mg
Recorded listing: General benefit
Source prices (unrounded): $0.1825; ministry $0.1825
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02380080
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=86592
Interchangeable products
ACT Venlafaxine XR · DIN 02304325 · $0.1825
Apo-Venlafaxine XR · DIN 02331691 · $0.1825
Auro-Venlafaxine XR · DIN 02452847 · $0.1825
Effexor XR · DIN 02237280 · $0.1825
M-Venlafaxine XR · DIN 02471299 · $0.1825
Mint-Venlafaxine XR · DIN 02522985 · $0.1825
PMS-Venlafaxine XR · DIN 02278553 · $0.1825
PMSC-Venlafaxine XR · DIN 02521482 · $0.1825
Sandoz Venlafaxine XR · DIN 02310325 · $0.1825
Teva-Venlafaxine XR · DIN 02275031 · $0.1825
Venlafaxine XR · DIN 02354721 · $0.1825
Venlafaxine XR · DIN 02385937 · $0.1825
Venlafaxine XR · DIN 02489686 · $0.1825
Venlafaxine XR · DIN 02516543 · $0.1825
Shortage status: active shortage (reported 2026-04-13, estimated to end 2026-09-11, last updated 2026-08-17); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02380080
Shortage record checked 2026-09-13T08:10:21.292534+00:00
Venlafaxine XR · DIN 02354721 · 75mg · extended release capsule
General benefitMarketed · checked 2026-09-02
Write on scriptno code needed
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Brand vs generic price
Lowest DBP recovery rule under medically necessary no-substitution claims:
6.2 Medically Necessary "No Substitution" Claims
The Side Effect Reporting Form will not have to be renewed. However, the
pharmacy must maintain a copy of the prescription that contains a direction that
there be no substitution and the required Health Canada Side Effect Reporting Form
(completed and signed by the prescriber). The prescriber must write “No
Substitution” or “No Sub” on renewal or subsequent new written prescriptions, and
indicate “No Substitution” on subsequent new oral prescriptions. The dispenser will
be reimbursed the DBP plus a mark-up and the lesser of the posted usual and
customary fee or the ODB dispensing fee minus the applicable ODB co-payment
amount. Where a completed Side Effect Reporting Form is not available at the
pharmacy during an inspection, the difference between the cost of the higher-cost
product and the lowest DBP listed for the interchangeable category will be
recovered.
(ontario.ca, Revision #17; 2026-08-03 ↗)
6.2 Medically Necessary "No Substitution" Claims
The Ministry will provide reimbursement of a higher-cost interchangeable product in
medically necessary circumstances where a patient has experienced a significant
adverse reaction with two (2) lower-cost interchangeable drug products, where
available. When a prescriber identifies a patient for which it is medically necessary
that a higher cost interchangeable product be provided, the prescriber must:
• Complete, sign and forward to the pharmacist a copy of the Health Canada
side effect reporting form for each lower-cost interchangeable drug product
trialed (Side Effect Reporting Form[s]); and
• Write “No Substitution” or “No Sub” on a written prescription or indicate “No
Substitution” to the pharmacist in the case of a verbal prescription.
The prescriber should keep a copy of the completed form in the patient’s record for
future use and reference.
In the case of a written prescription, when the pharmacist or dispensing physician
receives a prescription with the written notation “No Substitution” or “No Sub”,
reimbursement will be provided for the higher-cost interchangeable product only if
the prescription is accompanied by a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed.
This form must be completely filled out noting the details of the adverse reaction
and signed by the prescriber.
In the case of a verbal prescription, the prescriber must satisfy the operator of the
pharmacy or dispensing physician that a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed
has been completed and signed by the prescriber. A written record of this verbal
prescription and the completed Health Canada Side Effect Reporting Form must be
received by the pharmacy prior to claim submission.
Upon receipt, the pharmacist must:
• Fax, submit online or mail the completed and signed form to Health Canada’s
Canada Vigilance Program; and
• Retain his or her copy of the completed and signed Side Effect Reporting
Form.
(ontario.ca, Revision #17; 2026-08-03 ↗)1 brand, same coverage
Venlafaxine XR · DIN 02354721
Manufacturer: Sanis Health Inc.; listing date 2011-08-04
Health Canada: Marketed since 2023-05-23 · brand VENLAFAXINE XR · ATC N06AX16 VENLAFAXINE · form Capsule (extended-release) · route Oral · ingredients VENLAFAXINE (VENLAFAXINE HYDROCHLORIDE) 75 MG · company Sanis health inc · schedule Prescription
Check this DIN again · Health Canada product recordVenlafaxine XR: Formulary list price $0.1825/unit (unit not stated in source; not the patient's cost)
Ministry pays: $0.1825 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=83989 · Verify on the e-Formulary ↗ (DIN 02354721)
Source record
DIN 02354721: Venlafaxine XR
Raw flags: sec3=Y
Item: 281604088; group id 474; item number 1194; lccId None; manufacturer id SAI
Source form: ER Cap; strength: 75mg
Recorded listing: General benefit
Source prices (unrounded): $0.1825; ministry $0.1825
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02354721
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=83989
Interchangeable products
ACT Venlafaxine XR · DIN 02304325 · $0.1825
Apo-Venlafaxine XR · DIN 02331691 · $0.1825
Auro-Venlafaxine XR · DIN 02452847 · $0.1825
Effexor XR · DIN 02237280 · $0.1825
M-Venlafaxine XR · DIN 02471299 · $0.1825
Mint-Venlafaxine XR · DIN 02522985 · $0.1825
PMS-Venlafaxine XR · DIN 02278553 · $0.1825
PMSC-Venlafaxine XR · DIN 02521482 · $0.1825
Sandoz Venlafaxine XR · DIN 02310325 · $0.1825
Taro-Venlafaxine XR · DIN 02380080 · $0.1825
Teva-Venlafaxine XR · DIN 02275031 · $0.1825
Venlafaxine XR · DIN 02385937 · $0.1825
Venlafaxine XR · DIN 02489686 · $0.1825
Venlafaxine XR · DIN 02516543 · $0.1825
Shortage status: resolved shortage (ended 2024-12-02); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02354721
Shortage record checked 2026-09-13T08:10:21.292534+00:00
Venlafaxine XR · DIN 02385937 · 75mg · extended release capsule
General benefitMarketed · checked 2026-09-02
Write on scriptno code needed
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Brand vs generic price
Lowest DBP recovery rule under medically necessary no-substitution claims:
6.2 Medically Necessary "No Substitution" Claims
The Side Effect Reporting Form will not have to be renewed. However, the
pharmacy must maintain a copy of the prescription that contains a direction that
there be no substitution and the required Health Canada Side Effect Reporting Form
(completed and signed by the prescriber). The prescriber must write “No
Substitution” or “No Sub” on renewal or subsequent new written prescriptions, and
indicate “No Substitution” on subsequent new oral prescriptions. The dispenser will
be reimbursed the DBP plus a mark-up and the lesser of the posted usual and
customary fee or the ODB dispensing fee minus the applicable ODB co-payment
amount. Where a completed Side Effect Reporting Form is not available at the
pharmacy during an inspection, the difference between the cost of the higher-cost
product and the lowest DBP listed for the interchangeable category will be
recovered.
(ontario.ca, Revision #17; 2026-08-03 ↗)
6.2 Medically Necessary "No Substitution" Claims
The Ministry will provide reimbursement of a higher-cost interchangeable product in
medically necessary circumstances where a patient has experienced a significant
adverse reaction with two (2) lower-cost interchangeable drug products, where
available. When a prescriber identifies a patient for which it is medically necessary
that a higher cost interchangeable product be provided, the prescriber must:
• Complete, sign and forward to the pharmacist a copy of the Health Canada
side effect reporting form for each lower-cost interchangeable drug product
trialed (Side Effect Reporting Form[s]); and
• Write “No Substitution” or “No Sub” on a written prescription or indicate “No
Substitution” to the pharmacist in the case of a verbal prescription.
The prescriber should keep a copy of the completed form in the patient’s record for
future use and reference.
In the case of a written prescription, when the pharmacist or dispensing physician
receives a prescription with the written notation “No Substitution” or “No Sub”,
reimbursement will be provided for the higher-cost interchangeable product only if
the prescription is accompanied by a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed.
This form must be completely filled out noting the details of the adverse reaction
and signed by the prescriber.
In the case of a verbal prescription, the prescriber must satisfy the operator of the
pharmacy or dispensing physician that a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed
has been completed and signed by the prescriber. A written record of this verbal
prescription and the completed Health Canada Side Effect Reporting Form must be
received by the pharmacy prior to claim submission.
Upon receipt, the pharmacist must:
• Fax, submit online or mail the completed and signed form to Health Canada’s
Canada Vigilance Program; and
• Retain his or her copy of the completed and signed Side Effect Reporting
Form.
(ontario.ca, Revision #17; 2026-08-03 ↗)1 brand, same coverage
Venlafaxine XR · DIN 02385937
Manufacturer: Sivem Pharmaceuticals ULC; listing date 2020-06-30
Health Canada: Marketed since 2018-06-08 · brand VENLAFAXINE XR · ATC N06AX16 VENLAFAXINE · form Capsule (extended-release) · route Oral · ingredients VENLAFAXINE (VENLAFAXINE HYDROCHLORIDE) 75 MG · company Sivem pharmaceuticals ulc · schedule Prescription
Check this DIN again · Health Canada product recordVenlafaxine XR: Formulary list price $0.1825/unit (unit not stated in source; not the patient's cost)
Ministry pays: $0.1825 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=87154 · Verify on the e-Formulary ↗ (DIN 02385937)
Source record
DIN 02385937: Venlafaxine XR
Raw flags: sec3=Y
Item: 281604088; group id 474; item number 1194; lccId None; manufacturer id SIV
Source form: ER Cap; strength: 75mg
Recorded listing: General benefit
Source prices (unrounded): $0.1825; ministry $0.1825
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02385937
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=87154
Interchangeable products
ACT Venlafaxine XR · DIN 02304325 · $0.1825
Apo-Venlafaxine XR · DIN 02331691 · $0.1825
Auro-Venlafaxine XR · DIN 02452847 · $0.1825
Effexor XR · DIN 02237280 · $0.1825
M-Venlafaxine XR · DIN 02471299 · $0.1825
Mint-Venlafaxine XR · DIN 02522985 · $0.1825
PMS-Venlafaxine XR · DIN 02278553 · $0.1825
PMSC-Venlafaxine XR · DIN 02521482 · $0.1825
Sandoz Venlafaxine XR · DIN 02310325 · $0.1825
Taro-Venlafaxine XR · DIN 02380080 · $0.1825
Teva-Venlafaxine XR · DIN 02275031 · $0.1825
Venlafaxine XR · DIN 02354721 · $0.1825
Venlafaxine XR · DIN 02489686 · $0.1825
Venlafaxine XR · DIN 02516543 · $0.1825
Shortage status: resolved shortage (ended 2018-07-02); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02385937
Shortage record checked 2026-09-13T08:10:21.292534+00:00
Venlafaxine XR · DIN 02489686 · 75mg · extended release capsule
General benefitMarketed · checked 2026-09-02
Write on scriptno code needed
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Brand vs generic price
Lowest DBP recovery rule under medically necessary no-substitution claims:
6.2 Medically Necessary "No Substitution" Claims
The Side Effect Reporting Form will not have to be renewed. However, the
pharmacy must maintain a copy of the prescription that contains a direction that
there be no substitution and the required Health Canada Side Effect Reporting Form
(completed and signed by the prescriber). The prescriber must write “No
Substitution” or “No Sub” on renewal or subsequent new written prescriptions, and
indicate “No Substitution” on subsequent new oral prescriptions. The dispenser will
be reimbursed the DBP plus a mark-up and the lesser of the posted usual and
customary fee or the ODB dispensing fee minus the applicable ODB co-payment
amount. Where a completed Side Effect Reporting Form is not available at the
pharmacy during an inspection, the difference between the cost of the higher-cost
product and the lowest DBP listed for the interchangeable category will be
recovered.
(ontario.ca, Revision #17; 2026-08-03 ↗)
6.2 Medically Necessary "No Substitution" Claims
The Ministry will provide reimbursement of a higher-cost interchangeable product in
medically necessary circumstances where a patient has experienced a significant
adverse reaction with two (2) lower-cost interchangeable drug products, where
available. When a prescriber identifies a patient for which it is medically necessary
that a higher cost interchangeable product be provided, the prescriber must:
• Complete, sign and forward to the pharmacist a copy of the Health Canada
side effect reporting form for each lower-cost interchangeable drug product
trialed (Side Effect Reporting Form[s]); and
• Write “No Substitution” or “No Sub” on a written prescription or indicate “No
Substitution” to the pharmacist in the case of a verbal prescription.
The prescriber should keep a copy of the completed form in the patient’s record for
future use and reference.
In the case of a written prescription, when the pharmacist or dispensing physician
receives a prescription with the written notation “No Substitution” or “No Sub”,
reimbursement will be provided for the higher-cost interchangeable product only if
the prescription is accompanied by a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed.
This form must be completely filled out noting the details of the adverse reaction
and signed by the prescriber.
In the case of a verbal prescription, the prescriber must satisfy the operator of the
pharmacy or dispensing physician that a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed
has been completed and signed by the prescriber. A written record of this verbal
prescription and the completed Health Canada Side Effect Reporting Form must be
received by the pharmacy prior to claim submission.
Upon receipt, the pharmacist must:
• Fax, submit online or mail the completed and signed form to Health Canada’s
Canada Vigilance Program; and
• Retain his or her copy of the completed and signed Side Effect Reporting
Form.
(ontario.ca, Revision #17; 2026-08-03 ↗)1 brand, same coverage
Venlafaxine XR · DIN 02489686
Manufacturer: Laboratoire Riva Inc.; listing date 2024-11-29
Health Canada: Marketed since 2019-08-07 · brand VENLAFAXINE XR · ATC N06AX16 VENLAFAXINE · form Capsule (extended-release) · route Oral · ingredients VENLAFAXINE (VENLAFAXINE HYDROCHLORIDE) 75 MG · company Laboratoire riva inc. · schedule Prescription
Check this DIN again · Health Canada product recordVenlafaxine XR: Formulary list price $0.1825/unit (unit not stated in source; not the patient's cost)
Ministry pays: $0.1825 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=97975 · Verify on the e-Formulary ↗ (DIN 02489686)
Source record
DIN 02489686: Venlafaxine XR
Raw flags: sec3=Y
Item: 281604088; group id 474; item number 1194; lccId None; manufacturer id RIA
Source form: ER Cap; strength: 75mg
Recorded listing: General benefit
Source prices (unrounded): $0.1825; ministry $0.1825
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02489686
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=97975
Interchangeable products
ACT Venlafaxine XR · DIN 02304325 · $0.1825
Apo-Venlafaxine XR · DIN 02331691 · $0.1825
Auro-Venlafaxine XR · DIN 02452847 · $0.1825
Effexor XR · DIN 02237280 · $0.1825
M-Venlafaxine XR · DIN 02471299 · $0.1825
Mint-Venlafaxine XR · DIN 02522985 · $0.1825
PMS-Venlafaxine XR · DIN 02278553 · $0.1825
PMSC-Venlafaxine XR · DIN 02521482 · $0.1825
Sandoz Venlafaxine XR · DIN 02310325 · $0.1825
Taro-Venlafaxine XR · DIN 02380080 · $0.1825
Teva-Venlafaxine XR · DIN 02275031 · $0.1825
Venlafaxine XR · DIN 02354721 · $0.1825
Venlafaxine XR · DIN 02385937 · $0.1825
Venlafaxine XR · DIN 02516543 · $0.1825
Shortage status: no shortage or discontinuation reported (checked 2026-09-13T08:10:21.292534+00:00); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02489686
Shortage record checked 2026-09-13T08:10:21.292534+00:00
Venlafaxine XR · DIN 02516543 · 75mg · extended release capsule
General benefitMarketed · checked 2026-09-02
Write on scriptno code needed
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Brand vs generic price
Lowest DBP recovery rule under medically necessary no-substitution claims:
6.2 Medically Necessary "No Substitution" Claims
The Side Effect Reporting Form will not have to be renewed. However, the
pharmacy must maintain a copy of the prescription that contains a direction that
there be no substitution and the required Health Canada Side Effect Reporting Form
(completed and signed by the prescriber). The prescriber must write “No
Substitution” or “No Sub” on renewal or subsequent new written prescriptions, and
indicate “No Substitution” on subsequent new oral prescriptions. The dispenser will
be reimbursed the DBP plus a mark-up and the lesser of the posted usual and
customary fee or the ODB dispensing fee minus the applicable ODB co-payment
amount. Where a completed Side Effect Reporting Form is not available at the
pharmacy during an inspection, the difference between the cost of the higher-cost
product and the lowest DBP listed for the interchangeable category will be
recovered.
(ontario.ca, Revision #17; 2026-08-03 ↗)
6.2 Medically Necessary "No Substitution" Claims
The Ministry will provide reimbursement of a higher-cost interchangeable product in
medically necessary circumstances where a patient has experienced a significant
adverse reaction with two (2) lower-cost interchangeable drug products, where
available. When a prescriber identifies a patient for which it is medically necessary
that a higher cost interchangeable product be provided, the prescriber must:
• Complete, sign and forward to the pharmacist a copy of the Health Canada
side effect reporting form for each lower-cost interchangeable drug product
trialed (Side Effect Reporting Form[s]); and
• Write “No Substitution” or “No Sub” on a written prescription or indicate “No
Substitution” to the pharmacist in the case of a verbal prescription.
The prescriber should keep a copy of the completed form in the patient’s record for
future use and reference.
In the case of a written prescription, when the pharmacist or dispensing physician
receives a prescription with the written notation “No Substitution” or “No Sub”,
reimbursement will be provided for the higher-cost interchangeable product only if
the prescription is accompanied by a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed.
This form must be completely filled out noting the details of the adverse reaction
and signed by the prescriber.
In the case of a verbal prescription, the prescriber must satisfy the operator of the
pharmacy or dispensing physician that a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed
has been completed and signed by the prescriber. A written record of this verbal
prescription and the completed Health Canada Side Effect Reporting Form must be
received by the pharmacy prior to claim submission.
Upon receipt, the pharmacist must:
• Fax, submit online or mail the completed and signed form to Health Canada’s
Canada Vigilance Program; and
• Retain his or her copy of the completed and signed Side Effect Reporting
Form.
(ontario.ca, Revision #17; 2026-08-03 ↗)1 brand, same coverage
Venlafaxine XR · DIN 02516543
Manufacturer: Jamp Pharma Corporation; listing date 2022-02-28
Health Canada: Marketed since 2022-01-13 · brand VENLAFAXINE XR · ATC N06AX16 VENLAFAXINE · form Capsule (extended-release) · route Oral · ingredients VENLAFAXINE (VENLAFAXINE HYDROCHLORIDE) 75 MG · company Jamp pharma corporation · schedule Prescription
Check this DIN again · Health Canada product recordVenlafaxine XR: Formulary list price $0.1825/unit (unit not stated in source; not the patient's cost)
Ministry pays: $0.1825 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=100589 · Verify on the e-Formulary ↗ (DIN 02516543)
Source record
DIN 02516543: Venlafaxine XR
Raw flags: sec3=Y
Item: 281604088; group id 474; item number 1194; lccId None; manufacturer id JPC
Source form: ER Cap; strength: 75mg
Recorded listing: General benefit
Source prices (unrounded): $0.1825; ministry $0.1825
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02516543
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=100589
Interchangeable products
ACT Venlafaxine XR · DIN 02304325 · $0.1825
Apo-Venlafaxine XR · DIN 02331691 · $0.1825
Auro-Venlafaxine XR · DIN 02452847 · $0.1825
Effexor XR · DIN 02237280 · $0.1825
M-Venlafaxine XR · DIN 02471299 · $0.1825
Mint-Venlafaxine XR · DIN 02522985 · $0.1825
PMS-Venlafaxine XR · DIN 02278553 · $0.1825
PMSC-Venlafaxine XR · DIN 02521482 · $0.1825
Sandoz Venlafaxine XR · DIN 02310325 · $0.1825
Taro-Venlafaxine XR · DIN 02380080 · $0.1825
Teva-Venlafaxine XR · DIN 02275031 · $0.1825
Venlafaxine XR · DIN 02354721 · $0.1825
Venlafaxine XR · DIN 02385937 · $0.1825
Venlafaxine XR · DIN 02489686 · $0.1825
Shortage status: resolved shortage (ended 2026-07-17); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02516543
Shortage record checked 2026-09-13T08:10:21.292534+00:00
ACT Venlafaxine XR · DIN 02304333 · 150mg · extended release capsule
General benefitMarketed · checked 2026-09-02
Write on scriptno code needed
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Brand vs generic price
Lowest DBP recovery rule under medically necessary no-substitution claims:
6.2 Medically Necessary "No Substitution" Claims
The Side Effect Reporting Form will not have to be renewed. However, the
pharmacy must maintain a copy of the prescription that contains a direction that
there be no substitution and the required Health Canada Side Effect Reporting Form
(completed and signed by the prescriber). The prescriber must write “No
Substitution” or “No Sub” on renewal or subsequent new written prescriptions, and
indicate “No Substitution” on subsequent new oral prescriptions. The dispenser will
be reimbursed the DBP plus a mark-up and the lesser of the posted usual and
customary fee or the ODB dispensing fee minus the applicable ODB co-payment
amount. Where a completed Side Effect Reporting Form is not available at the
pharmacy during an inspection, the difference between the cost of the higher-cost
product and the lowest DBP listed for the interchangeable category will be
recovered.
(ontario.ca, Revision #17; 2026-08-03 ↗)
6.2 Medically Necessary "No Substitution" Claims
The Ministry will provide reimbursement of a higher-cost interchangeable product in
medically necessary circumstances where a patient has experienced a significant
adverse reaction with two (2) lower-cost interchangeable drug products, where
available. When a prescriber identifies a patient for which it is medically necessary
that a higher cost interchangeable product be provided, the prescriber must:
• Complete, sign and forward to the pharmacist a copy of the Health Canada
side effect reporting form for each lower-cost interchangeable drug product
trialed (Side Effect Reporting Form[s]); and
• Write “No Substitution” or “No Sub” on a written prescription or indicate “No
Substitution” to the pharmacist in the case of a verbal prescription.
The prescriber should keep a copy of the completed form in the patient’s record for
future use and reference.
In the case of a written prescription, when the pharmacist or dispensing physician
receives a prescription with the written notation “No Substitution” or “No Sub”,
reimbursement will be provided for the higher-cost interchangeable product only if
the prescription is accompanied by a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed.
This form must be completely filled out noting the details of the adverse reaction
and signed by the prescriber.
In the case of a verbal prescription, the prescriber must satisfy the operator of the
pharmacy or dispensing physician that a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed
has been completed and signed by the prescriber. A written record of this verbal
prescription and the completed Health Canada Side Effect Reporting Form must be
received by the pharmacy prior to claim submission.
Upon receipt, the pharmacist must:
• Fax, submit online or mail the completed and signed form to Health Canada’s
Canada Vigilance Program; and
• Retain his or her copy of the completed and signed Side Effect Reporting
Form.
(ontario.ca, Revision #17; 2026-08-03 ↗)1 brand, same coverage
ACT Venlafaxine XR · DIN 02304333
Manufacturer: Teva Canada Limited; listing date 2008-04-09
Health Canada: Marketed since 2019-03-01 · brand ACT VENLAFAXINE XR · ATC N06AX16 VENLAFAXINE · form Capsule (extended-release) · route Oral · ingredients VENLAFAXINE (VENLAFAXINE HYDROCHLORIDE) 150 MG · company Teva canada limited · schedule Prescription
Check this DIN again · Health Canada product recordACT Venlafaxine XR: Formulary list price $0.1927/unit (unit not stated in source; not the patient's cost)
Ministry pays: $0.1927 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=78962 · Verify on the e-Formulary ↗ (DIN 02304333)
Source record
DIN 02304333: ACT Venlafaxine XR
Raw flags: sec3=Y
Item: 281604089; group id 474; item number 1195; lccId None; manufacturer id TEV
Source form: ER Cap; strength: 150mg
Recorded listing: General benefit
Source prices (unrounded): $0.1927; ministry $0.1927
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02304333
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=78962
Interchangeable products
Apo-Venlafaxine XR · DIN 02331705 · $0.1927
Auro-Venlafaxine XR · DIN 02452855 · $0.1927
Effexor XR · DIN 02237282 · $0.1927
M-Venlafaxine XR · DIN 02471302 · $0.1927
Mint-Venlafaxine XR · DIN 02522993 · $0.1927
PMS-Venlafaxine XR · DIN 02278561 · $0.1927
PMSC-Venlafaxine XR · DIN 02521474 · $0.1927
Sandoz Venlafaxine XR · DIN 02310333 · $0.1927
Taro-Venlafaxine XR · DIN 02380099 · $0.1927
Teva-Venlafaxine XR · DIN 02275058 · $0.1927
Venlafaxine XR · DIN 02354748 · $0.1927
Venlafaxine XR · DIN 02385945 · $0.1927
Venlafaxine XR · DIN 02489694 · $0.1927
Venlafaxine XR · DIN 02516551 · $0.1927
Shortage status: discontinued (2018-06-30, reported by ACTAVIS PHARMA COMPANY); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02304333
Shortage record checked 2026-09-13T08:10:21.292534+00:00
Auro-Venlafaxine XR · DIN 02452855 · 150mg · extended release capsule
General benefitMarketed · checked 2026-09-02
Write on scriptno code needed
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Brand vs generic price
Lowest DBP recovery rule under medically necessary no-substitution claims:
6.2 Medically Necessary "No Substitution" Claims
The Side Effect Reporting Form will not have to be renewed. However, the
pharmacy must maintain a copy of the prescription that contains a direction that
there be no substitution and the required Health Canada Side Effect Reporting Form
(completed and signed by the prescriber). The prescriber must write “No
Substitution” or “No Sub” on renewal or subsequent new written prescriptions, and
indicate “No Substitution” on subsequent new oral prescriptions. The dispenser will
be reimbursed the DBP plus a mark-up and the lesser of the posted usual and
customary fee or the ODB dispensing fee minus the applicable ODB co-payment
amount. Where a completed Side Effect Reporting Form is not available at the
pharmacy during an inspection, the difference between the cost of the higher-cost
product and the lowest DBP listed for the interchangeable category will be
recovered.
(ontario.ca, Revision #17; 2026-08-03 ↗)
6.2 Medically Necessary "No Substitution" Claims
The Ministry will provide reimbursement of a higher-cost interchangeable product in
medically necessary circumstances where a patient has experienced a significant
adverse reaction with two (2) lower-cost interchangeable drug products, where
available. When a prescriber identifies a patient for which it is medically necessary
that a higher cost interchangeable product be provided, the prescriber must:
• Complete, sign and forward to the pharmacist a copy of the Health Canada
side effect reporting form for each lower-cost interchangeable drug product
trialed (Side Effect Reporting Form[s]); and
• Write “No Substitution” or “No Sub” on a written prescription or indicate “No
Substitution” to the pharmacist in the case of a verbal prescription.
The prescriber should keep a copy of the completed form in the patient’s record for
future use and reference.
In the case of a written prescription, when the pharmacist or dispensing physician
receives a prescription with the written notation “No Substitution” or “No Sub”,
reimbursement will be provided for the higher-cost interchangeable product only if
the prescription is accompanied by a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed.
This form must be completely filled out noting the details of the adverse reaction
and signed by the prescriber.
In the case of a verbal prescription, the prescriber must satisfy the operator of the
pharmacy or dispensing physician that a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed
has been completed and signed by the prescriber. A written record of this verbal
prescription and the completed Health Canada Side Effect Reporting Form must be
received by the pharmacy prior to claim submission.
Upon receipt, the pharmacist must:
• Fax, submit online or mail the completed and signed form to Health Canada’s
Canada Vigilance Program; and
• Retain his or her copy of the completed and signed Side Effect Reporting
Form.
(ontario.ca, Revision #17; 2026-08-03 ↗)1 brand, same coverage
Auro-Venlafaxine XR · DIN 02452855
Manufacturer: Auro Pharma Inc.; listing date 2016-05-31
Health Canada: Marketed since 2016-03-14 · brand AURO-VENLAFAXINE XR · ATC N06AX16 VENLAFAXINE · form Capsule (extended-release) · route Oral · ingredients VENLAFAXINE (VENLAFAXINE HYDROCHLORIDE) 150 MG · company Auro pharma inc · schedule Prescription
Check this DIN again · Health Canada product recordAuro-Venlafaxine XR: Formulary list price $0.1927/unit (unit not stated in source; not the patient's cost)
Ministry pays: $0.1927 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=93926 · Verify on the e-Formulary ↗ (DIN 02452855)
Source record
DIN 02452855: Auro-Venlafaxine XR
Raw flags: sec3=Y
Item: 281604089; group id 474; item number 1195; lccId None; manufacturer id AUR
Source form: ER Cap; strength: 150mg
Recorded listing: General benefit
Source prices (unrounded): $0.1927; ministry $0.1927
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02452855
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=93926
Interchangeable products
ACT Venlafaxine XR · DIN 02304333 · $0.1927
Apo-Venlafaxine XR · DIN 02331705 · $0.1927
Effexor XR · DIN 02237282 · $0.1927
M-Venlafaxine XR · DIN 02471302 · $0.1927
Mint-Venlafaxine XR · DIN 02522993 · $0.1927
PMS-Venlafaxine XR · DIN 02278561 · $0.1927
PMSC-Venlafaxine XR · DIN 02521474 · $0.1927
Sandoz Venlafaxine XR · DIN 02310333 · $0.1927
Taro-Venlafaxine XR · DIN 02380099 · $0.1927
Teva-Venlafaxine XR · DIN 02275058 · $0.1927
Venlafaxine XR · DIN 02354748 · $0.1927
Venlafaxine XR · DIN 02385945 · $0.1927
Venlafaxine XR · DIN 02489694 · $0.1927
Venlafaxine XR · DIN 02516551 · $0.1927
Shortage status: resolved shortage (ended 2024-03-27); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02452855
Shortage record checked 2026-09-13T08:10:21.292534+00:00