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PERINDOPRIL ERBUMINE & INDAPAMIDE

All products: general benefit

Other products in the same Health Canada class (C09B, C09BA) — coverage varies; not interchangeable

  • Cilazapril + hydrochlorothiazide (Inhibace Plus): general benefit
  • Hydrochlorothiazide + lisinopril (Zestoretic): general benefit, Not a benefit
  • Hydrochlorothiazide + quinapril (Accuretic): general benefit, Not a benefit
  • Hydrochlorothiazide + ramipril (Altace HCT): general benefit, Not a benefit
  • Enalapril + hydrochlorothiazide (Vaseretic): not a benefit
  • Amlodipine + perindopril arginine (Viacoram): not a benefit

Coversyl Plus · DIN 02246569 · 4mg & 1.25mg · tablet

General benefitMarketed · checked 2026-09-02
StatusGeneral benefit
Write on scriptno code needed
Patient paysPatient pays: program not supplied; amount cannot be determined.
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Savings card: innoviCares lists Coversyl Plus (Ontario list dated 2026-09-10) — pays part of the brand-versus-generic difference after other coverage; free sign-up. (innovicares.ca ↗)
1 brand, same coverage
Coversyl Plus · DIN 02246569 Manufacturer: Servier Canada Inc.; listing date 2007-04-02 Health Canada: Marketed since 2003-10-10 · brand COVERSYL PLUS · ATC C09BA04 PERINDOPRIL AND DIURETICS, C09BA04 PERINDOPRIL AND DIURETICS · form Tablet · route Oral · ingredients PERINDOPRIL ERBUMINE 4 MG, INDAPAMIDE 1.25 MG · company Servier canada inc · schedule Prescription
Check this DIN again · Health Canada product record

Ministry pays: $0.2556 per source unit.

Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.

Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=70752 · Verify on the e-Formulary ↗ (DIN 02246569)

Source record
DIN 02246569: Coversyl Plus Raw flags: chronicUseMed=Y, sec3=Y Item: 240800264; group id 344; item number 0782; lccId None; manufacturer id SEV Source form: Tab; strength: 4mg & 1.25mg Recorded listing: General benefit; chronic-use medication (100-day supply rule, dispensing-fee limit) Source prices (unrounded): $1.2317; ministry $0.2556 Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02246569 Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=70752
Interchangeable products
Apo-Perindopril-Indapamide · DIN 02297574 · $0.2556 Jamp Perindopril / Indapamide · DIN 02554127 · $0.2556 PMS-Perindopril-Indapamide · DIN 02538008 · $0.2556 Perindopril Erbumine/Indapamide · DIN 02479834 · $0.2556 Perindopril/Indapamide · DIN 02519720 · $0.2556 Sandoz Perindopril Erbumine/Indapamide · DIN 02470438 · $0.2556 Teva-Perindopril/Indapamide · DIN 02464020 · $0.2556
Shortage status: resolved shortage (ended 2020-11-17); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada) Source: https://healthproductshortages.ca/search?term=02246569
Shortage record checked 2026-09-13T08:10:21.292534+00:00
Other drugs in the same formulary class (24:08 Hypotensive Drugs (For Diuretics See 40:28)) and how they are covered

Matched class: 24:08 Hypotensive Drugs (For Diuretics See 40:28)

Drug-class inventory only. Lists recorded Ontario formulary products, not every Canadian medication; does not recommend treatment. Covered without a code on the Ontario formulary: CANDESARTAN CILEXETIL, CANDESARTAN CILEXETIL & HYDROCHLOROTHIAZIDE, CILAZAPRIL & HYDROCHLOROTHIAZIDE, LABETALOL HCL, LOSARTAN POTASSIUM, LOSARTAN POTASSIUM & HYDROCHLOROTHIAZIDE, MINOXIDIL, OLMESARTAN MEDOXOMIL, OLMESARTAN MEDOXOMIL & HYDROCHLOROTHIAZIDE, PERINDOPRIL ERBUMINE, PINDOLOL & HYDROCHLOROTHIAZIDE, TELMISARTAN, TELMISARTAN & AMLODIPINE BESYLATE, TELMISARTAN & HYDROCHLOROTHIAZIDE, VALSARTAN & HYDROCHLOROTHIAZIDE Some products covered without a code (check the product listing): ATENOLOL & CHLORTHALIDONE, BENAZEPRIL, CAPTOPRIL, CILAZAPRIL, CLONIDINE HCL, DOXAZOSIN MESYLATE, ENALAPRIL MALEATE, FELODIPINE, FOSINOPRIL SODIUM, HYDRALAZINE HCL, IRBESARTAN, IRBESARTAN & HYDROCHLOROTHIAZIDE, LISINOPRIL, LISINOPRIL & HYDROCHLOROTHIAZIDE, METHYLDOPA, NIFEDIPINE, PINDOLOL, PRAZOSIN HCL, QUINAPRIL, QUINAPRIL & HYDROCHLOROTHIAZIDE, RAMIPRIL, RAMIPRIL & HYDROCHLOROTHIAZIDE, TERAZOSIN HCL, TRANDOLAPRIL, VALSARTAN, VERAPAMIL HCL 24:08 Hypotensive Drugs (For Diuretics See 40:28)

CILAZAPRIL & HYDROCHLOROTHIAZIDE

· 2 products · General benefit · strengths: 5mg/12.5mg · Tab

LISINOPRIL & HYDROCHLOROTHIAZIDE

· 18 products · General benefit (10), Listed, not a benefit (2), Off-Formulary Interchangeable, not an ODB benefit (6) · strengths: 10mg & 12.5mg, 20mg & 12.5mg, 20mg & 25mg, 20mg/25mg · Tab

QUINAPRIL & HYDROCHLOROTHIAZIDE

· 11 products · Listed, not a benefit (3), General benefit (8) · strengths: 10mg & 12.5mg, 20mg & 12.5mg, 20mg & 25mg · Tab

RAMIPRIL & HYDROCHLOROTHIAZIDE

· 12 products · Listed, not a benefit (2), General benefit (10) · strengths: 2.5mg & 12.5mg, 5mg & 12.5mg, 5mg & 25mg, 10mg & 12.5mg, 10mg & 25mg · Tab

ENALAPRIL MALEATE & HYDROCHLOROTHIAZIDE

· 4 products · Off-Formulary Interchangeable, not an ODB benefit · strengths: 5mg & 12.5mg, 10mg & 25mg · Tab

PERINDOPRIL ARGININE & AMLODIPINE BESYLATE

· 9 products · Off-Formulary Interchangeable, not an ODB benefit · strengths: 3.5mg & 2.5mg, 7mg & 5mg, 14mg & 10mg · Tab

ATENOLOL & CHLORTHALIDONE

· 4 products · Listed, not a benefit (2), General benefit (2) · strengths: 50 & 25mg, 100 & 25mg · Tab

BENAZEPRIL

· 6 products · Listed, not a benefit (3), General benefit (3) · strengths: 5mg, 10mg, 20mg · Tab

CANDESARTAN CILEXETIL

· 59 products · General benefit · strengths: 4mg, 8mg, 16mg, 32mg · Tab

CANDESARTAN CILEXETIL & HYDROCHLOROTHIAZIDE

· 21 products · General benefit · strengths: 16mg & 12.5mg, 32mg & 12.5mg, 32mg & 25mg · Tab

CAPTOPRIL

· 14 products · Limited Use, codes 707, 723 (2), Listed, not a benefit (4), General benefit (8) · strengths: 5mg/5mL, 25mg/5mL, 12.5mg, 25mg, 50mg, 100mg · Oral Sol, Tab

CILAZAPRIL

· 8 products · Listed, not a benefit (2), General benefit (6) · strengths: 1mg, 2.5mg, 5mg · Tab Source: formulary-ed43-front-matter.txt Part V; ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26; class 24:08 and 35 more
Full class listing Related classes: 24:04 Cardiac Drugs, 24:06 Antilipemic Drugs, 24:12 Vasodilating Drugs, 24:32 Renin-Angiotensin Aldosterone Inhibitors Same formulary class, not same indication: class membership alone does not establish equivalent uses.
Other drugs whose Health Canada label lists a similar indication: hypertension
From Health Canada product monographs; label wording only, not a treatment recommendation. Matching is lexical and uses one held product label per generic; formulations and qualifying criteria may differ. Covered without a code on the Ontario formulary: CANDESARTAN CILEXETIL, CANDESARTAN CILEXETIL & HYDROCHLOROTHIAZIDE, CILAZAPRIL & HYDROCHLOROTHIAZIDE ACEBUTOLOL HCL · Listed, not a benefit (3), General benefit (6) INDICATIONS AND CLINICAL USE APO-ACEBUTOLOL is indicated for the following:  Treatment of mild to moderate hypertension.  Long-term management of patients with angina pectoris due to ischemic heart disease. PM: https://pdf.hres.ca/dpd_pm/00047998.PDF; date October 24, 2018; DIN 02147602; fetched 2026-09-10 Product monograph AMLODIPINE · Limited Use, codes 645, 706 (1), Off-Formulary Interchangeable, not an ODB benefit (11), General benefit (44) 1 INDICATIONS NORVASC (amlodipine besylate tablets) is indicated for: • Hypertension NORVASC is indicated in the treatment of mild to moderate essential hypertension. PM: https://pdf.hres.ca/dpd_pm/00071908.PDF; date AUG 02, 2023; DIN 00878928; fetched 2026-09-10 Product monograph AZILSARTAN MEDOXOMIL · Off-Formulary Interchangeable, not an ODB benefit 1 Part 1: Healthcare Professional Information Indications • EDARBI (azilsartan medoxomil) is an angiotensin II receptor blocker (ARB) indicated for the treatment of mild to moderate essential hypertension. PM: https://pdf.hres.ca/dpd_pm/00082489.PDF; date 2025-10-24; DIN 02381389; fetched 2026-09-10 Product monograph BENAZEPRIL · Listed, not a benefit (3), General benefit (3) Indications BENAZEPRIL (benazepril hydrochloride tablets) is indicated for:  Treatment of mild to moderate essential hypertension. PM: https://pdf.hres.ca/dpd_pm/00080887.PDF; date 2025-06-24; DIN 02273918; fetched 2026-09-10 Product monograph CANDESARTAN CILEXETIL · General benefit • Heart Failure o The treatment of NYHA Class II and III heart failure with ejection fraction ≤ 40% in addition to standard therapy, with or without an ACE inhibitor. 1.1 Pediatrics Pediatrics (6 to 17 years of age): • Hypertension ATACAND is indicated for the treatment of essential hypertension in children and adolescents 6 to 17 years of age (see 7.1.3 Pediatrics, 14 CLINICAL TRIALS). PM: https://pdf.hres.ca/dpd_pm/00085412.PDF; date JUL 17, 2026; DIN 02239090; fetched 2026-09-10 Product monograph • Hypertension PM: https://pdf.hres.ca/dpd_pm/00085412.PDF; date JUL 17, 2026; DIN 02239090; fetched 2026-09-10 Product monograph CANDESARTAN CILEXETIL & HYDROCHLOROTHIAZIDE · General benefit 1 INDICATIONS ATACAND PLUS (candesartan cilexetil/hydrochlorothiazide) is indicated for: • the treatment of essential hypertension in patients for whom combination therapy is appropriate. PM: https://pdf.hres.ca/dpd_pm/00076288.PDF; date JUN 18, 2001; DIN 02244021; fetched 2026-09-10 Product monograph CHLORTHALIDONE · Listed, not a benefit (1), General benefit (2) 1 INDICATIONS APO-CHLORTHALIDONE (chlorthalidone) is indicated for: • Treatment of hypertension. PM: https://pdf.hres.ca/dpd_pm/00069909.PDF; date MAR 14, 2023; DIN 00360279; fetched 2026-09-10 Product monograph CILAZAPRIL & HYDROCHLOROTHIAZIDE · General benefit 1 INDICATIONS INHIBACE PLUS (cilazapril and hydrochlorothiazide) is indicated for:  treatment of mild to moderate essential hypertension in patients for whom combination therapy with both cilazapril and hydrochlorothiazide is appropriate. PM: https://pdf.hres.ca/dpd_pm/00066994.PDF; date September 07, 1995; DIN 02181479; fetched 2026-09-10 Product monograph CLONIDINE HCL · Off-Formulary Interchangeable, not an ODB benefit (7), Listed, not a benefit (2), General benefit (8) INDICATIONS AND CLINICAL USE TEVA-CLONIDINE (clonidine hydrochloride) is indicated for the treatment of hypertension. PM: https://pdf.hres.ca/dpd_pm/00024986.PDF; date April 25, 2014; DIN 02046121; fetched 2026-09-10 Product monograph ENALAPRIL MALEATE & HYDROCHLOROTHIAZIDE · Off-Formulary Interchangeable, not an ODB benefit 1 INDICATIONS VASERETIC® (enalapril and hydrochlorothiazide) is indicated for:  Treatment of essential hypertension in patients for whom this combination therapy with enalapril and hydrochlorothiazide is appropriate. PM: https://pdf.hres.ca/dpd_pm/00068096.PDF; date November 4, 2022; DIN 00657298; fetched 2026-09-10 Product monograph and 20 more Coverage source: ON formulary extract 2026-08-26
What the Health Canada label says it is for
1. Indications COVERSYL® PLUS LD (perindopril erbumine / indapamide) is indicated for the initial treatment of mild to moderate essential hypertension. COVERSYL® PLUS and COVERSYL® PLUS HD (perindopril erbumine / indapamide) are indicated for the treatment of mild to moderate essential hypertension in patients for whom combination therapy is appropriate. COVERSYL® PLUS and COVERSYL® PLUS HD are not indicated for initial therapy. Patients in whom perindopril and indapamide are initiated simultaneously can develop symptomatic hypotension (see 9 Drug Interactions– Drug-Drug Interactions - Concomitant ACE Inhibitor and Diuretic Therapy). Patients should be titrated on the individual drugs. If the fixed combination represents the dosage determined by this titration, the use of COVERSYL® PLUS or COVERSYL® PLUS HD may prove to be more convenient in the management of patients. If during maintenance therapy dosage adjustment is necessary, it is advisable to use individual drugs (see 4 Dosage and Administration). The safety and efficacy of COVERSYL® PLUS LD / COVERSYL® PLUS / COVERSYL® PLUS HD in renovascular hypertension and in congestive heart failure have not been established and theref… https://pdf.hres.ca/dpd_pm/00085950.PDF PM date: 2026-08-27 Source product: COVERSYL PLUS LD; DIN 02246568; fetched 2026-09-10 Product monograph posted by Health Canada; excerpt for lookup only.