ENALAPRIL MALEATE
All strengths: General benefit; same patient cost rules
Shared coverage and patient cost rules
StatusGeneral benefit
Patient paysPatient pays: program not supplied; amount cannot be determined.
Other products in the same Health Canada class (C09AA) — coverage varies; not interchangeable
- Benazepril (Lotensin): general benefit, Not a benefit
- Captopril (Noyada): general benefit, Limited Use 707, 723, Not a benefit
- Cilazapril (Inhibace): general benefit, Not a benefit
- Fosinopril (Monopril): general benefit, Not a benefit
- Lisinopril (Prinivil): general benefit, Not a benefit
- Perindopril erbumine (Coversyl): general benefit
3 more in the class list below
Apo-Enalapril · DIN 02020025 · 2.5mg · tablet
General benefitMarketed · checked 2026-09-02
Write on scriptno code needed
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
1 brand, same coverage
Apo-Enalapril · DIN 02020025
Manufacturer: Apotex Inc.; listing date 2007-12-19
Daily cost (source): $0.1863
Health Canada: Marketed since 1993-12-31 · brand APO-ENALAPRIL · ATC C09AA02 ENALAPRIL · form Tablet · route Oral · ingredients ENALAPRIL MALEATE 2.5 MG · company Apotex inc · schedule Prescription
Check this DIN again · Health Canada product recordApo-Enalapril: Formulary list price $0.1863/unit (unit not stated in source; not the patient's cost)
Ministry pays: $0.1863 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=14385 · Verify on the e-Formulary ↗ (DIN 02020025)
Source record
DIN 02020025: Apo-Enalapril
Raw flags: chronicUseMed=Y, sec3=Y
Item: 240800149; group id 322; item number 0715; lccId None; manufacturer id APX
Source form: Tab; strength: 2.5mg
Recorded listing: General benefit; chronic-use medication (100-day supply rule, dispensing-fee limit)
Source prices (unrounded): $0.1863; ministry $0.1863
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02020025
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=14385
Interchangeable products
Co Enalapril · DIN 02291878 · $0.1863
Enalapril · DIN 02400650 · $0.1863
Enalapril · DIN 02442957 · $0.1863
Jamp-Enalapril · DIN 02474786 · $0.1863
Mar-Enalapril · DIN 02459450 · $0.1863
Mylan-Enalapril · DIN 02300036 · $0.1863
Novo-Enalapril · DIN 02300680 · $0.1863
Ran-Enalapril · DIN 02352230 · $0.1863
Ratio-Enalapril · DIN 02299984 · $0.1863
Sandoz Enalapril · DIN 02299933 · $0.1863
Taro-Enalapril · DIN 02300117 · $0.1863
Vasotec · DIN 00851795 · not recorded
Shortage status: resolved shortage (ended 2021-03-05); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02020025
Shortage record checked 2026-09-13T08:10:21.292534+00:00
Co Enalapril · DIN 02291878 · 2.5mg · tablet
General benefitMarketed · checked 2026-09-02
Write on scriptno code needed
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
1 brand, same coverage
Co Enalapril · DIN 02291878
Manufacturer: Cobalt Pharmaceuticals Company; listing date 2007-12-19
Daily cost (source): $0.1863
Health Canada: Marketed since 2017-08-18 · brand ACT ENALAPRIL · ATC C09AA02 ENALAPRIL · form Tablet · route Oral · ingredients ENALAPRIL SODIUM (ENALAPRIL MALEATE) 2 MG · company Teva canada limited · schedule Prescription
Check this DIN again · Health Canada product recordCo Enalapril: Formulary list price $0.1863/unit (unit not stated in source; not the patient's cost)
Ministry pays: $0.1863 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=77724 · Verify on the e-Formulary ↗ (DIN 02291878)
Source record
DIN 02291878: Co Enalapril
Raw flags: chronicUseMed=Y, sec3=Y
Item: 240800149; group id 322; item number 0715; lccId None; manufacturer id COB
Source form: Tab; strength: 2.5mg
Recorded listing: General benefit; chronic-use medication (100-day supply rule, dispensing-fee limit)
Source prices (unrounded): $0.1863; ministry $0.1863
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02291878
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=77724
Therapeutic Notes (formulary)
** Each tablet is made with 2.5mg of enalapril maleate that is equivalent to 2mg of enalapril sodium, in the finished tablets.
Interchangeable products
Apo-Enalapril · DIN 02020025 · $0.1863
Enalapril · DIN 02400650 · $0.1863
Enalapril · DIN 02442957 · $0.1863
Jamp-Enalapril · DIN 02474786 · $0.1863
Mar-Enalapril · DIN 02459450 · $0.1863
Mylan-Enalapril · DIN 02300036 · $0.1863
Novo-Enalapril · DIN 02300680 · $0.1863
Ran-Enalapril · DIN 02352230 · $0.1863
Ratio-Enalapril · DIN 02299984 · $0.1863
Sandoz Enalapril · DIN 02299933 · $0.1863
Taro-Enalapril · DIN 02300117 · $0.1863
Vasotec · DIN 00851795 · not recorded
Shortage status: resolved shortage (ended 2025-02-19); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02291878
Shortage record checked 2026-09-13T08:10:21.292534+00:00
Enalapril · DIN 02400650 · 2.5mg · tablet
General benefitMarketed · checked 2026-09-02
Write on scriptno code needed
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
1 brand, same coverage
Enalapril · DIN 02400650
Manufacturer: Sanis Health Inc.; listing date 2022-02-28
Daily cost (source): $0.1863
Health Canada: Marketed since 2022-01-07 · brand ENALAPRIL · ATC C09AA02 ENALAPRIL · form Tablet · route Oral · ingredients ENALAPRIL MALEATE 2.5 MG · company Sanis health inc · schedule Prescription
Check this DIN again · Health Canada product recordEnalapril: Formulary list price $0.1863/unit (unit not stated in source; not the patient's cost)
Ministry pays: $0.1863 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=88543 · Verify on the e-Formulary ↗ (DIN 02400650)
Source record
DIN 02400650: Enalapril
Raw flags: chronicUseMed=Y, sec3=Y
Item: 240800149; group id 322; item number 0715; lccId None; manufacturer id SAI
Source form: Tab; strength: 2.5mg
Recorded listing: General benefit; chronic-use medication (100-day supply rule, dispensing-fee limit)
Source prices (unrounded): $0.1863; ministry $0.1863
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02400650
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=88543
Interchangeable products
Apo-Enalapril · DIN 02020025 · $0.1863
Co Enalapril · DIN 02291878 · $0.1863
Enalapril · DIN 02442957 · $0.1863
Jamp-Enalapril · DIN 02474786 · $0.1863
Mar-Enalapril · DIN 02459450 · $0.1863
Mylan-Enalapril · DIN 02300036 · $0.1863
Novo-Enalapril · DIN 02300680 · $0.1863
Ran-Enalapril · DIN 02352230 · $0.1863
Ratio-Enalapril · DIN 02299984 · $0.1863
Sandoz Enalapril · DIN 02299933 · $0.1863
Taro-Enalapril · DIN 02300117 · $0.1863
Vasotec · DIN 00851795 · not recorded
Shortage status: resolved shortage (ended 2022-01-03); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02400650
Shortage record checked 2026-09-13T08:10:21.292534+00:00
Enalapril · DIN 02442957 · 2.5mg · tablet
General benefitMarketed · checked 2026-09-02
Write on scriptno code needed
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
1 brand, same coverage
Enalapril · DIN 02442957
Manufacturer: Sivem Pharmaceuticals ULC; listing date 2020-11-30
Daily cost (source): $0.1863
Health Canada: Marketed since 2018-10-04 · brand ENALAPRIL · ATC C09AA02 ENALAPRIL · form Tablet · route Oral · ingredients ENALAPRIL SODIUM (ENALAPRIL MALEATE) 2 MG · company Sivem pharmaceuticals ulc · schedule Prescription
Check this DIN again · Health Canada product recordEnalapril: Formulary list price $0.1863/unit (unit not stated in source; not the patient's cost)
Ministry pays: $0.1863 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=92748 · Verify on the e-Formulary ↗ (DIN 02442957)
Source record
DIN 02442957: Enalapril
Raw flags: chronicUseMed=Y, sec3=Y
Item: 240800149; group id 322; item number 0715; lccId None; manufacturer id SIV
Source form: Tab; strength: 2.5mg
Recorded listing: General benefit; chronic-use medication (100-day supply rule, dispensing-fee limit)
Source prices (unrounded): $0.1863; ministry $0.1863
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02442957
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=92748
Interchangeable products
Apo-Enalapril · DIN 02020025 · $0.1863
Co Enalapril · DIN 02291878 · $0.1863
Enalapril · DIN 02400650 · $0.1863
Jamp-Enalapril · DIN 02474786 · $0.1863
Mar-Enalapril · DIN 02459450 · $0.1863
Mylan-Enalapril · DIN 02300036 · $0.1863
Novo-Enalapril · DIN 02300680 · $0.1863
Ran-Enalapril · DIN 02352230 · $0.1863
Ratio-Enalapril · DIN 02299984 · $0.1863
Sandoz Enalapril · DIN 02299933 · $0.1863
Taro-Enalapril · DIN 02300117 · $0.1863
Vasotec · DIN 00851795 · not recorded
Shortage status: resolved shortage (ended 2020-03-25); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02442957
Shortage record checked 2026-09-13T08:10:21.292534+00:00
Jamp-Enalapril · DIN 02474786 · 2.5mg · tablet
General benefitMarketed · checked 2026-09-02
Write on scriptno code needed
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
1 brand, same coverage
Jamp-Enalapril · DIN 02474786
Manufacturer: Jamp Pharma Corporation; listing date 2019-04-30
Daily cost (source): $0.1863
Health Canada: Marketed since 2019-02-25 · brand JAMP ENALAPRIL · ATC C09AA02 ENALAPRIL · form Tablet · route Oral · ingredients ENALAPRIL MALEATE 2.5 MG · company Jamp pharma corporation · schedule Prescription
Check this DIN again · Health Canada product recordJamp-Enalapril: Formulary list price $0.1863/unit (unit not stated in source; not the patient's cost)
Ministry pays: $0.1863 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=96497 · Verify on the e-Formulary ↗ (DIN 02474786)
Source record
DIN 02474786: Jamp-Enalapril
Raw flags: chronicUseMed=Y, sec3=Y
Item: 240800149; group id 322; item number 0715; lccId None; manufacturer id JPC
Source form: Tab; strength: 2.5mg
Recorded listing: General benefit; chronic-use medication (100-day supply rule, dispensing-fee limit)
Source prices (unrounded): $0.1863; ministry $0.1863
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02474786
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=96497
Interchangeable products
Apo-Enalapril · DIN 02020025 · $0.1863
Co Enalapril · DIN 02291878 · $0.1863
Enalapril · DIN 02400650 · $0.1863
Enalapril · DIN 02442957 · $0.1863
Mar-Enalapril · DIN 02459450 · $0.1863
Mylan-Enalapril · DIN 02300036 · $0.1863
Novo-Enalapril · DIN 02300680 · $0.1863
Ran-Enalapril · DIN 02352230 · $0.1863
Ratio-Enalapril · DIN 02299984 · $0.1863
Sandoz Enalapril · DIN 02299933 · $0.1863
Taro-Enalapril · DIN 02300117 · $0.1863
Vasotec · DIN 00851795 · not recorded
Shortage status: resolved shortage (ended 2024-07-03); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02474786
Shortage record checked 2026-09-13T08:10:21.292534+00:00
Mar-Enalapril · DIN 02459450 · 2.5mg · tablet
General benefitMarketed · checked 2026-09-02
Write on scriptno code needed
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
1 brand, same coverage
Mar-Enalapril · DIN 02459450
Manufacturer: Marcan Pharmaceuticals Inc.; listing date 2019-06-28
Daily cost (source): $0.1863
Health Canada: Marketed since 2019-03-20 · brand MAR-ENALAPRIL · ATC C09AA02 ENALAPRIL · form Tablet · route Oral · ingredients ENALAPRIL MALEATE 2.5 MG · company Marcan pharmaceuticals inc · schedule Prescription
Check this DIN again · Health Canada product recordMar-Enalapril: Formulary list price $0.1863/unit (unit not stated in source; not the patient's cost)
Ministry pays: $0.1863 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=94669 · Verify on the e-Formulary ↗ (DIN 02459450)
Source record
DIN 02459450: Mar-Enalapril
Raw flags: chronicUseMed=Y, sec3=Y
Item: 240800149; group id 322; item number 0715; lccId None; manufacturer id MAR
Source form: Tab; strength: 2.5mg
Recorded listing: General benefit; chronic-use medication (100-day supply rule, dispensing-fee limit)
Source prices (unrounded): $0.1863; ministry $0.1863
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02459450
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=94669
Interchangeable products
Apo-Enalapril · DIN 02020025 · $0.1863
Co Enalapril · DIN 02291878 · $0.1863
Enalapril · DIN 02400650 · $0.1863
Enalapril · DIN 02442957 · $0.1863
Jamp-Enalapril · DIN 02474786 · $0.1863
Mylan-Enalapril · DIN 02300036 · $0.1863
Novo-Enalapril · DIN 02300680 · $0.1863
Ran-Enalapril · DIN 02352230 · $0.1863
Ratio-Enalapril · DIN 02299984 · $0.1863
Sandoz Enalapril · DIN 02299933 · $0.1863
Taro-Enalapril · DIN 02300117 · $0.1863
Vasotec · DIN 00851795 · not recorded
Shortage status: no shortage or discontinuation reported (checked 2026-09-13T08:10:21.292534+00:00); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02459450
Shortage record checked 2026-09-13T08:10:21.292534+00:00
Ran-Enalapril · DIN 02352230 · 2.5mg · tablet
General benefitMarketed · checked 2026-09-02
Write on scriptno code needed
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
1 brand, same coverage
Ran-Enalapril · DIN 02352230
Manufacturer: Ranbaxy Pharmaceuticals Canada Inc.; listing date 2011-01-07
Daily cost (source): $0.1863
Health Canada: Marketed since 2022-02-15 · brand TARO-ENALAPRIL · ATC C09AA02 ENALAPRIL · form Tablet · route Oral · ingredients ENALAPRIL SODIUM 2 MG · company Sun pharma canada inc · schedule Prescription
Check this DIN again · Health Canada product recordRan-Enalapril: Formulary list price $0.1863/unit (unit not stated in source; not the patient's cost)
Ministry pays: $0.1863 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=83747 · Verify on the e-Formulary ↗ (DIN 02352230)
Source record
DIN 02352230: Ran-Enalapril
Raw flags: chronicUseMed=Y, sec3=Y
Item: 240800149; group id 322; item number 0715; lccId None; manufacturer id RAN
Source form: Tab; strength: 2.5mg
Recorded listing: General benefit; chronic-use medication (100-day supply rule, dispensing-fee limit)
Source prices (unrounded): $0.1863; ministry $0.1863
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02352230
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=83747
Interchangeable products
Apo-Enalapril · DIN 02020025 · $0.1863
Co Enalapril · DIN 02291878 · $0.1863
Enalapril · DIN 02400650 · $0.1863
Enalapril · DIN 02442957 · $0.1863
Jamp-Enalapril · DIN 02474786 · $0.1863
Mar-Enalapril · DIN 02459450 · $0.1863
Mylan-Enalapril · DIN 02300036 · $0.1863
Novo-Enalapril · DIN 02300680 · $0.1863
Ratio-Enalapril · DIN 02299984 · $0.1863
Sandoz Enalapril · DIN 02299933 · $0.1863
Taro-Enalapril · DIN 02300117 · $0.1863
Vasotec · DIN 00851795 · not recorded
Shortage status: resolved shortage (ended 2025-04-10); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02352230
Shortage record checked 2026-09-13T08:10:21.292534+00:00
Apo-Enalapril · DIN 02019884 · 5mg · tablet
General benefitMarketed · checked 2026-09-02
Write on scriptno code needed
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Brand vs generic price
Lowest DBP recovery rule under medically necessary no-substitution claims:
6.2 Medically Necessary "No Substitution" Claims
The Side Effect Reporting Form will not have to be renewed. However, the
pharmacy must maintain a copy of the prescription that contains a direction that
there be no substitution and the required Health Canada Side Effect Reporting Form
(completed and signed by the prescriber). The prescriber must write “No
Substitution” or “No Sub” on renewal or subsequent new written prescriptions, and
indicate “No Substitution” on subsequent new oral prescriptions. The dispenser will
be reimbursed the DBP plus a mark-up and the lesser of the posted usual and
customary fee or the ODB dispensing fee minus the applicable ODB co-payment
amount. Where a completed Side Effect Reporting Form is not available at the
pharmacy during an inspection, the difference between the cost of the higher-cost
product and the lowest DBP listed for the interchangeable category will be
recovered.
(ontario.ca, Revision #17; 2026-08-03 ↗)
6.2 Medically Necessary "No Substitution" Claims
The Ministry will provide reimbursement of a higher-cost interchangeable product in
medically necessary circumstances where a patient has experienced a significant
adverse reaction with two (2) lower-cost interchangeable drug products, where
available. When a prescriber identifies a patient for which it is medically necessary
that a higher cost interchangeable product be provided, the prescriber must:
• Complete, sign and forward to the pharmacist a copy of the Health Canada
side effect reporting form for each lower-cost interchangeable drug product
trialed (Side Effect Reporting Form[s]); and
• Write “No Substitution” or “No Sub” on a written prescription or indicate “No
Substitution” to the pharmacist in the case of a verbal prescription.
The prescriber should keep a copy of the completed form in the patient’s record for
future use and reference.
In the case of a written prescription, when the pharmacist or dispensing physician
receives a prescription with the written notation “No Substitution” or “No Sub”,
reimbursement will be provided for the higher-cost interchangeable product only if
the prescription is accompanied by a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed.
This form must be completely filled out noting the details of the adverse reaction
and signed by the prescriber.
In the case of a verbal prescription, the prescriber must satisfy the operator of the
pharmacy or dispensing physician that a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed
has been completed and signed by the prescriber. A written record of this verbal
prescription and the completed Health Canada Side Effect Reporting Form must be
received by the pharmacy prior to claim submission.
Upon receipt, the pharmacist must:
• Fax, submit online or mail the completed and signed form to Health Canada’s
Canada Vigilance Program; and
• Retain his or her copy of the completed and signed Side Effect Reporting
Form.
(ontario.ca, Revision #17; 2026-08-03 ↗)1 brand, same coverage
Apo-Enalapril · DIN 02019884
Manufacturer: Apotex Inc.; listing date 2007-12-19
Daily cost (source): $0.2203
Health Canada: Marketed since 1993-12-31 · brand APO-ENALAPRIL · ATC C09AA02 ENALAPRIL · form Tablet · route Oral · ingredients ENALAPRIL MALEATE 5 MG · company Apotex inc · schedule Prescription
Check this DIN again · Health Canada product recordApo-Enalapril: Formulary list price $0.2203/unit (unit not stated in source; not the patient's cost)
Ministry pays: $0.2203 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=14386 · Verify on the e-Formulary ↗ (DIN 02019884)
Source record
DIN 02019884: Apo-Enalapril
Raw flags: chronicUseMed=Y, sec3=Y
Item: 240800105; group id 322; item number 0716; lccId None; manufacturer id APX
Source form: Tab; strength: 5mg
Recorded listing: General benefit; chronic-use medication (100-day supply rule, dispensing-fee limit)
Source prices (unrounded): $0.2203; ministry $0.2203
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02019884
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=14386
Interchangeable products
Co Enalapril · DIN 02291886 · $0.2203
Enalapril · DIN 02400669 · $0.2203
Enalapril · DIN 02442965 · $0.2203
Jamp-Enalapril · DIN 02474794 · $0.2203
Mar-Enalapril · DIN 02459469 · $0.2203
Mylan-Enalapril · DIN 02300044 · $0.2203
Ran-Enalapril · DIN 02352249 · $0.2203
Ratio-Enalapril · DIN 02299992 · $0.2203
Sandoz Enalapril · DIN 02299941 · $0.2203
Taro-Enalapril · DIN 02300125 · $0.2203
Teva-Enalapril · DIN 02233005 · $0.2203
Vasotec · DIN 00708879 · $0.2203
Shortage status: resolved shortage (ended 2024-11-07); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02019884
Shortage record checked 2026-09-13T08:10:21.292534+00:00
Co Enalapril · DIN 02291886 · 5mg · tablet
General benefitMarketed · checked 2026-09-02
Write on scriptno code needed
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Brand vs generic price
Lowest DBP recovery rule under medically necessary no-substitution claims:
6.2 Medically Necessary "No Substitution" Claims
The Side Effect Reporting Form will not have to be renewed. However, the
pharmacy must maintain a copy of the prescription that contains a direction that
there be no substitution and the required Health Canada Side Effect Reporting Form
(completed and signed by the prescriber). The prescriber must write “No
Substitution” or “No Sub” on renewal or subsequent new written prescriptions, and
indicate “No Substitution” on subsequent new oral prescriptions. The dispenser will
be reimbursed the DBP plus a mark-up and the lesser of the posted usual and
customary fee or the ODB dispensing fee minus the applicable ODB co-payment
amount. Where a completed Side Effect Reporting Form is not available at the
pharmacy during an inspection, the difference between the cost of the higher-cost
product and the lowest DBP listed for the interchangeable category will be
recovered.
(ontario.ca, Revision #17; 2026-08-03 ↗)
6.2 Medically Necessary "No Substitution" Claims
The Ministry will provide reimbursement of a higher-cost interchangeable product in
medically necessary circumstances where a patient has experienced a significant
adverse reaction with two (2) lower-cost interchangeable drug products, where
available. When a prescriber identifies a patient for which it is medically necessary
that a higher cost interchangeable product be provided, the prescriber must:
• Complete, sign and forward to the pharmacist a copy of the Health Canada
side effect reporting form for each lower-cost interchangeable drug product
trialed (Side Effect Reporting Form[s]); and
• Write “No Substitution” or “No Sub” on a written prescription or indicate “No
Substitution” to the pharmacist in the case of a verbal prescription.
The prescriber should keep a copy of the completed form in the patient’s record for
future use and reference.
In the case of a written prescription, when the pharmacist or dispensing physician
receives a prescription with the written notation “No Substitution” or “No Sub”,
reimbursement will be provided for the higher-cost interchangeable product only if
the prescription is accompanied by a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed.
This form must be completely filled out noting the details of the adverse reaction
and signed by the prescriber.
In the case of a verbal prescription, the prescriber must satisfy the operator of the
pharmacy or dispensing physician that a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed
has been completed and signed by the prescriber. A written record of this verbal
prescription and the completed Health Canada Side Effect Reporting Form must be
received by the pharmacy prior to claim submission.
Upon receipt, the pharmacist must:
• Fax, submit online or mail the completed and signed form to Health Canada’s
Canada Vigilance Program; and
• Retain his or her copy of the completed and signed Side Effect Reporting
Form.
(ontario.ca, Revision #17; 2026-08-03 ↗)1 brand, same coverage
Co Enalapril · DIN 02291886
Manufacturer: Cobalt Pharmaceuticals Company; listing date 2007-12-19
Daily cost (source): $0.2203
Health Canada: Marketed since 2017-08-18 · brand ACT ENALAPRIL · ATC C09AA02 ENALAPRIL · form Tablet · route Oral · ingredients ENALAPRIL SODIUM (ENALAPRIL MALEATE) 4 MG · company Teva canada limited · schedule Prescription
Check this DIN again · Health Canada product recordCo Enalapril: Formulary list price $0.2203/unit (unit not stated in source; not the patient's cost)
Ministry pays: $0.2203 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=77725 · Verify on the e-Formulary ↗ (DIN 02291886)
Source record
DIN 02291886: Co Enalapril
Raw flags: chronicUseMed=Y, sec3=Y
Item: 240800105; group id 322; item number 0716; lccId None; manufacturer id COB
Source form: Tab; strength: 5mg
Recorded listing: General benefit; chronic-use medication (100-day supply rule, dispensing-fee limit)
Source prices (unrounded): $0.2203; ministry $0.2203
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02291886
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=77725
Therapeutic Notes (formulary)
** Each tablet is made with 5mg of enalapril maleate that is equivalent to 4mg of enalapril sodium, in the finished tablets.
Interchangeable products
Apo-Enalapril · DIN 02019884 · $0.2203
Enalapril · DIN 02400669 · $0.2203
Enalapril · DIN 02442965 · $0.2203
Jamp-Enalapril · DIN 02474794 · $0.2203
Mar-Enalapril · DIN 02459469 · $0.2203
Mylan-Enalapril · DIN 02300044 · $0.2203
Ran-Enalapril · DIN 02352249 · $0.2203
Ratio-Enalapril · DIN 02299992 · $0.2203
Sandoz Enalapril · DIN 02299941 · $0.2203
Taro-Enalapril · DIN 02300125 · $0.2203
Teva-Enalapril · DIN 02233005 · $0.2203
Vasotec · DIN 00708879 · $0.2203
Shortage status: discontinued (2017-04-07, reported by TEVA CANADA LIMITED); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02291886
Shortage record checked 2026-09-13T08:10:21.292534+00:00
Enalapril · DIN 02400669 · 5mg · tablet
General benefitMarketed · checked 2026-09-02
Write on scriptno code needed
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Brand vs generic price
Lowest DBP recovery rule under medically necessary no-substitution claims:
6.2 Medically Necessary "No Substitution" Claims
The Side Effect Reporting Form will not have to be renewed. However, the
pharmacy must maintain a copy of the prescription that contains a direction that
there be no substitution and the required Health Canada Side Effect Reporting Form
(completed and signed by the prescriber). The prescriber must write “No
Substitution” or “No Sub” on renewal or subsequent new written prescriptions, and
indicate “No Substitution” on subsequent new oral prescriptions. The dispenser will
be reimbursed the DBP plus a mark-up and the lesser of the posted usual and
customary fee or the ODB dispensing fee minus the applicable ODB co-payment
amount. Where a completed Side Effect Reporting Form is not available at the
pharmacy during an inspection, the difference between the cost of the higher-cost
product and the lowest DBP listed for the interchangeable category will be
recovered.
(ontario.ca, Revision #17; 2026-08-03 ↗)
6.2 Medically Necessary "No Substitution" Claims
The Ministry will provide reimbursement of a higher-cost interchangeable product in
medically necessary circumstances where a patient has experienced a significant
adverse reaction with two (2) lower-cost interchangeable drug products, where
available. When a prescriber identifies a patient for which it is medically necessary
that a higher cost interchangeable product be provided, the prescriber must:
• Complete, sign and forward to the pharmacist a copy of the Health Canada
side effect reporting form for each lower-cost interchangeable drug product
trialed (Side Effect Reporting Form[s]); and
• Write “No Substitution” or “No Sub” on a written prescription or indicate “No
Substitution” to the pharmacist in the case of a verbal prescription.
The prescriber should keep a copy of the completed form in the patient’s record for
future use and reference.
In the case of a written prescription, when the pharmacist or dispensing physician
receives a prescription with the written notation “No Substitution” or “No Sub”,
reimbursement will be provided for the higher-cost interchangeable product only if
the prescription is accompanied by a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed.
This form must be completely filled out noting the details of the adverse reaction
and signed by the prescriber.
In the case of a verbal prescription, the prescriber must satisfy the operator of the
pharmacy or dispensing physician that a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed
has been completed and signed by the prescriber. A written record of this verbal
prescription and the completed Health Canada Side Effect Reporting Form must be
received by the pharmacy prior to claim submission.
Upon receipt, the pharmacist must:
• Fax, submit online or mail the completed and signed form to Health Canada’s
Canada Vigilance Program; and
• Retain his or her copy of the completed and signed Side Effect Reporting
Form.
(ontario.ca, Revision #17; 2026-08-03 ↗)1 brand, same coverage
Enalapril · DIN 02400669
Manufacturer: Sanis Health Inc.; listing date 2022-02-28
Daily cost (source): $0.2203
Health Canada: Marketed since 2022-01-07 · brand ENALAPRIL · ATC C09AA02 ENALAPRIL · form Tablet · route Oral · ingredients ENALAPRIL MALEATE 5 MG · company Sanis health inc · schedule Prescription
Check this DIN again · Health Canada product recordEnalapril: Formulary list price $0.2203/unit (unit not stated in source; not the patient's cost)
Ministry pays: $0.2203 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=88544 · Verify on the e-Formulary ↗ (DIN 02400669)
Source record
DIN 02400669: Enalapril
Raw flags: chronicUseMed=Y, sec3=Y
Item: 240800105; group id 322; item number 0716; lccId None; manufacturer id SAI
Source form: Tab; strength: 5mg
Recorded listing: General benefit; chronic-use medication (100-day supply rule, dispensing-fee limit)
Source prices (unrounded): $0.2203; ministry $0.2203
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02400669
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=88544
Interchangeable products
Apo-Enalapril · DIN 02019884 · $0.2203
Co Enalapril · DIN 02291886 · $0.2203
Enalapril · DIN 02442965 · $0.2203
Jamp-Enalapril · DIN 02474794 · $0.2203
Mar-Enalapril · DIN 02459469 · $0.2203
Mylan-Enalapril · DIN 02300044 · $0.2203
Ran-Enalapril · DIN 02352249 · $0.2203
Ratio-Enalapril · DIN 02299992 · $0.2203
Sandoz Enalapril · DIN 02299941 · $0.2203
Taro-Enalapril · DIN 02300125 · $0.2203
Teva-Enalapril · DIN 02233005 · $0.2203
Vasotec · DIN 00708879 · $0.2203
Shortage status: resolved shortage (ended 2022-01-07); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02400669
Shortage record checked 2026-09-13T08:10:21.292534+00:00
Enalapril · DIN 02442965 · 5mg · tablet
General benefitMarketed · checked 2026-09-02
Write on scriptno code needed
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Brand vs generic price
Lowest DBP recovery rule under medically necessary no-substitution claims:
6.2 Medically Necessary "No Substitution" Claims
The Side Effect Reporting Form will not have to be renewed. However, the
pharmacy must maintain a copy of the prescription that contains a direction that
there be no substitution and the required Health Canada Side Effect Reporting Form
(completed and signed by the prescriber). The prescriber must write “No
Substitution” or “No Sub” on renewal or subsequent new written prescriptions, and
indicate “No Substitution” on subsequent new oral prescriptions. The dispenser will
be reimbursed the DBP plus a mark-up and the lesser of the posted usual and
customary fee or the ODB dispensing fee minus the applicable ODB co-payment
amount. Where a completed Side Effect Reporting Form is not available at the
pharmacy during an inspection, the difference between the cost of the higher-cost
product and the lowest DBP listed for the interchangeable category will be
recovered.
(ontario.ca, Revision #17; 2026-08-03 ↗)
6.2 Medically Necessary "No Substitution" Claims
The Ministry will provide reimbursement of a higher-cost interchangeable product in
medically necessary circumstances where a patient has experienced a significant
adverse reaction with two (2) lower-cost interchangeable drug products, where
available. When a prescriber identifies a patient for which it is medically necessary
that a higher cost interchangeable product be provided, the prescriber must:
• Complete, sign and forward to the pharmacist a copy of the Health Canada
side effect reporting form for each lower-cost interchangeable drug product
trialed (Side Effect Reporting Form[s]); and
• Write “No Substitution” or “No Sub” on a written prescription or indicate “No
Substitution” to the pharmacist in the case of a verbal prescription.
The prescriber should keep a copy of the completed form in the patient’s record for
future use and reference.
In the case of a written prescription, when the pharmacist or dispensing physician
receives a prescription with the written notation “No Substitution” or “No Sub”,
reimbursement will be provided for the higher-cost interchangeable product only if
the prescription is accompanied by a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed.
This form must be completely filled out noting the details of the adverse reaction
and signed by the prescriber.
In the case of a verbal prescription, the prescriber must satisfy the operator of the
pharmacy or dispensing physician that a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed
has been completed and signed by the prescriber. A written record of this verbal
prescription and the completed Health Canada Side Effect Reporting Form must be
received by the pharmacy prior to claim submission.
Upon receipt, the pharmacist must:
• Fax, submit online or mail the completed and signed form to Health Canada’s
Canada Vigilance Program; and
• Retain his or her copy of the completed and signed Side Effect Reporting
Form.
(ontario.ca, Revision #17; 2026-08-03 ↗)1 brand, same coverage
Enalapril · DIN 02442965
Manufacturer: Sivem Pharmaceuticals ULC; listing date 2020-11-30
Daily cost (source): $0.2203
Health Canada: Marketed since 2018-10-04 · brand ENALAPRIL · ATC C09AA02 ENALAPRIL · form Tablet · route Oral · ingredients ENALAPRIL SODIUM (ENALAPRIL MALEATE) 4 MG · company Sivem pharmaceuticals ulc · schedule Prescription
Check this DIN again · Health Canada product recordEnalapril: Formulary list price $0.2203/unit (unit not stated in source; not the patient's cost)
Ministry pays: $0.2203 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=92749 · Verify on the e-Formulary ↗ (DIN 02442965)
Source record
DIN 02442965: Enalapril
Raw flags: chronicUseMed=Y, sec3=Y
Item: 240800105; group id 322; item number 0716; lccId None; manufacturer id SIV
Source form: Tab; strength: 5mg
Recorded listing: General benefit; chronic-use medication (100-day supply rule, dispensing-fee limit)
Source prices (unrounded): $0.2203; ministry $0.2203
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02442965
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=92749
Interchangeable products
Apo-Enalapril · DIN 02019884 · $0.2203
Co Enalapril · DIN 02291886 · $0.2203
Enalapril · DIN 02400669 · $0.2203
Jamp-Enalapril · DIN 02474794 · $0.2203
Mar-Enalapril · DIN 02459469 · $0.2203
Mylan-Enalapril · DIN 02300044 · $0.2203
Ran-Enalapril · DIN 02352249 · $0.2203
Ratio-Enalapril · DIN 02299992 · $0.2203
Sandoz Enalapril · DIN 02299941 · $0.2203
Taro-Enalapril · DIN 02300125 · $0.2203
Teva-Enalapril · DIN 02233005 · $0.2203
Vasotec · DIN 00708879 · $0.2203
Shortage status: resolved shortage (ended 2018-10-19); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02442965
Shortage record checked 2026-09-13T08:10:21.292534+00:00
Jamp-Enalapril · DIN 02474794 · 5mg · tablet
General benefitMarketed · checked 2026-09-02
Write on scriptno code needed
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Brand vs generic price
Lowest DBP recovery rule under medically necessary no-substitution claims:
6.2 Medically Necessary "No Substitution" Claims
The Side Effect Reporting Form will not have to be renewed. However, the
pharmacy must maintain a copy of the prescription that contains a direction that
there be no substitution and the required Health Canada Side Effect Reporting Form
(completed and signed by the prescriber). The prescriber must write “No
Substitution” or “No Sub” on renewal or subsequent new written prescriptions, and
indicate “No Substitution” on subsequent new oral prescriptions. The dispenser will
be reimbursed the DBP plus a mark-up and the lesser of the posted usual and
customary fee or the ODB dispensing fee minus the applicable ODB co-payment
amount. Where a completed Side Effect Reporting Form is not available at the
pharmacy during an inspection, the difference between the cost of the higher-cost
product and the lowest DBP listed for the interchangeable category will be
recovered.
(ontario.ca, Revision #17; 2026-08-03 ↗)
6.2 Medically Necessary "No Substitution" Claims
The Ministry will provide reimbursement of a higher-cost interchangeable product in
medically necessary circumstances where a patient has experienced a significant
adverse reaction with two (2) lower-cost interchangeable drug products, where
available. When a prescriber identifies a patient for which it is medically necessary
that a higher cost interchangeable product be provided, the prescriber must:
• Complete, sign and forward to the pharmacist a copy of the Health Canada
side effect reporting form for each lower-cost interchangeable drug product
trialed (Side Effect Reporting Form[s]); and
• Write “No Substitution” or “No Sub” on a written prescription or indicate “No
Substitution” to the pharmacist in the case of a verbal prescription.
The prescriber should keep a copy of the completed form in the patient’s record for
future use and reference.
In the case of a written prescription, when the pharmacist or dispensing physician
receives a prescription with the written notation “No Substitution” or “No Sub”,
reimbursement will be provided for the higher-cost interchangeable product only if
the prescription is accompanied by a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed.
This form must be completely filled out noting the details of the adverse reaction
and signed by the prescriber.
In the case of a verbal prescription, the prescriber must satisfy the operator of the
pharmacy or dispensing physician that a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed
has been completed and signed by the prescriber. A written record of this verbal
prescription and the completed Health Canada Side Effect Reporting Form must be
received by the pharmacy prior to claim submission.
Upon receipt, the pharmacist must:
• Fax, submit online or mail the completed and signed form to Health Canada’s
Canada Vigilance Program; and
• Retain his or her copy of the completed and signed Side Effect Reporting
Form.
(ontario.ca, Revision #17; 2026-08-03 ↗)1 brand, same coverage
Jamp-Enalapril · DIN 02474794
Manufacturer: Jamp Pharma Corporation; listing date 2019-04-30
Daily cost (source): $0.2203
Health Canada: Marketed since 2019-02-25 · brand JAMP ENALAPRIL · ATC C09AA02 ENALAPRIL · form Tablet · route Oral · ingredients ENALAPRIL MALEATE 5 MG · company Jamp pharma corporation · schedule Prescription
Check this DIN again · Health Canada product recordJamp-Enalapril: Formulary list price $0.2203/unit (unit not stated in source; not the patient's cost)
Ministry pays: $0.2203 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=96498 · Verify on the e-Formulary ↗ (DIN 02474794)
Source record
DIN 02474794: Jamp-Enalapril
Raw flags: chronicUseMed=Y, sec3=Y
Item: 240800105; group id 322; item number 0716; lccId None; manufacturer id JPC
Source form: Tab; strength: 5mg
Recorded listing: General benefit; chronic-use medication (100-day supply rule, dispensing-fee limit)
Source prices (unrounded): $0.2203; ministry $0.2203
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02474794
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=96498
Interchangeable products
Apo-Enalapril · DIN 02019884 · $0.2203
Co Enalapril · DIN 02291886 · $0.2203
Enalapril · DIN 02400669 · $0.2203
Enalapril · DIN 02442965 · $0.2203
Mar-Enalapril · DIN 02459469 · $0.2203
Mylan-Enalapril · DIN 02300044 · $0.2203
Ran-Enalapril · DIN 02352249 · $0.2203
Ratio-Enalapril · DIN 02299992 · $0.2203
Sandoz Enalapril · DIN 02299941 · $0.2203
Taro-Enalapril · DIN 02300125 · $0.2203
Teva-Enalapril · DIN 02233005 · $0.2203
Vasotec · DIN 00708879 · $0.2203
Shortage status: resolved shortage (ended 2024-04-15); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02474794
Shortage record checked 2026-09-13T08:10:21.292534+00:00
Mar-Enalapril · DIN 02459469 · 5mg · tablet
General benefitMarketed · checked 2026-09-02
Write on scriptno code needed
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Brand vs generic price
Lowest DBP recovery rule under medically necessary no-substitution claims:
6.2 Medically Necessary "No Substitution" Claims
The Side Effect Reporting Form will not have to be renewed. However, the
pharmacy must maintain a copy of the prescription that contains a direction that
there be no substitution and the required Health Canada Side Effect Reporting Form
(completed and signed by the prescriber). The prescriber must write “No
Substitution” or “No Sub” on renewal or subsequent new written prescriptions, and
indicate “No Substitution” on subsequent new oral prescriptions. The dispenser will
be reimbursed the DBP plus a mark-up and the lesser of the posted usual and
customary fee or the ODB dispensing fee minus the applicable ODB co-payment
amount. Where a completed Side Effect Reporting Form is not available at the
pharmacy during an inspection, the difference between the cost of the higher-cost
product and the lowest DBP listed for the interchangeable category will be
recovered.
(ontario.ca, Revision #17; 2026-08-03 ↗)
6.2 Medically Necessary "No Substitution" Claims
The Ministry will provide reimbursement of a higher-cost interchangeable product in
medically necessary circumstances where a patient has experienced a significant
adverse reaction with two (2) lower-cost interchangeable drug products, where
available. When a prescriber identifies a patient for which it is medically necessary
that a higher cost interchangeable product be provided, the prescriber must:
• Complete, sign and forward to the pharmacist a copy of the Health Canada
side effect reporting form for each lower-cost interchangeable drug product
trialed (Side Effect Reporting Form[s]); and
• Write “No Substitution” or “No Sub” on a written prescription or indicate “No
Substitution” to the pharmacist in the case of a verbal prescription.
The prescriber should keep a copy of the completed form in the patient’s record for
future use and reference.
In the case of a written prescription, when the pharmacist or dispensing physician
receives a prescription with the written notation “No Substitution” or “No Sub”,
reimbursement will be provided for the higher-cost interchangeable product only if
the prescription is accompanied by a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed.
This form must be completely filled out noting the details of the adverse reaction
and signed by the prescriber.
In the case of a verbal prescription, the prescriber must satisfy the operator of the
pharmacy or dispensing physician that a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed
has been completed and signed by the prescriber. A written record of this verbal
prescription and the completed Health Canada Side Effect Reporting Form must be
received by the pharmacy prior to claim submission.
Upon receipt, the pharmacist must:
• Fax, submit online or mail the completed and signed form to Health Canada’s
Canada Vigilance Program; and
• Retain his or her copy of the completed and signed Side Effect Reporting
Form.
(ontario.ca, Revision #17; 2026-08-03 ↗)1 brand, same coverage
Mar-Enalapril · DIN 02459469
Manufacturer: Marcan Pharmaceuticals Inc.; listing date 2019-06-28
Daily cost (source): $0.2203
Health Canada: Marketed since 2019-03-20 · brand MAR-ENALAPRIL · ATC C09AA02 ENALAPRIL · form Tablet · route Oral · ingredients ENALAPRIL MALEATE 5 MG · company Marcan pharmaceuticals inc · schedule Prescription
Check this DIN again · Health Canada product recordMar-Enalapril: Formulary list price $0.2203/unit (unit not stated in source; not the patient's cost)
Ministry pays: $0.2203 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=94670 · Verify on the e-Formulary ↗ (DIN 02459469)
Source record
DIN 02459469: Mar-Enalapril
Raw flags: chronicUseMed=Y, sec3=Y
Item: 240800105; group id 322; item number 0716; lccId None; manufacturer id MAR
Source form: Tab; strength: 5mg
Recorded listing: General benefit; chronic-use medication (100-day supply rule, dispensing-fee limit)
Source prices (unrounded): $0.2203; ministry $0.2203
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02459469
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=94670
Interchangeable products
Apo-Enalapril · DIN 02019884 · $0.2203
Co Enalapril · DIN 02291886 · $0.2203
Enalapril · DIN 02400669 · $0.2203
Enalapril · DIN 02442965 · $0.2203
Jamp-Enalapril · DIN 02474794 · $0.2203
Mylan-Enalapril · DIN 02300044 · $0.2203
Ran-Enalapril · DIN 02352249 · $0.2203
Ratio-Enalapril · DIN 02299992 · $0.2203
Sandoz Enalapril · DIN 02299941 · $0.2203
Taro-Enalapril · DIN 02300125 · $0.2203
Teva-Enalapril · DIN 02233005 · $0.2203
Vasotec · DIN 00708879 · $0.2203
Shortage status: no shortage or discontinuation reported (checked 2026-09-13T08:10:21.292534+00:00); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02459469
Shortage record checked 2026-09-13T08:10:21.292534+00:00
Ran-Enalapril · DIN 02352249 · 5mg · tablet
General benefitMarketed · checked 2026-09-02
Write on scriptno code needed
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Brand vs generic price
Lowest DBP recovery rule under medically necessary no-substitution claims:
6.2 Medically Necessary "No Substitution" Claims
The Side Effect Reporting Form will not have to be renewed. However, the
pharmacy must maintain a copy of the prescription that contains a direction that
there be no substitution and the required Health Canada Side Effect Reporting Form
(completed and signed by the prescriber). The prescriber must write “No
Substitution” or “No Sub” on renewal or subsequent new written prescriptions, and
indicate “No Substitution” on subsequent new oral prescriptions. The dispenser will
be reimbursed the DBP plus a mark-up and the lesser of the posted usual and
customary fee or the ODB dispensing fee minus the applicable ODB co-payment
amount. Where a completed Side Effect Reporting Form is not available at the
pharmacy during an inspection, the difference between the cost of the higher-cost
product and the lowest DBP listed for the interchangeable category will be
recovered.
(ontario.ca, Revision #17; 2026-08-03 ↗)
6.2 Medically Necessary "No Substitution" Claims
The Ministry will provide reimbursement of a higher-cost interchangeable product in
medically necessary circumstances where a patient has experienced a significant
adverse reaction with two (2) lower-cost interchangeable drug products, where
available. When a prescriber identifies a patient for which it is medically necessary
that a higher cost interchangeable product be provided, the prescriber must:
• Complete, sign and forward to the pharmacist a copy of the Health Canada
side effect reporting form for each lower-cost interchangeable drug product
trialed (Side Effect Reporting Form[s]); and
• Write “No Substitution” or “No Sub” on a written prescription or indicate “No
Substitution” to the pharmacist in the case of a verbal prescription.
The prescriber should keep a copy of the completed form in the patient’s record for
future use and reference.
In the case of a written prescription, when the pharmacist or dispensing physician
receives a prescription with the written notation “No Substitution” or “No Sub”,
reimbursement will be provided for the higher-cost interchangeable product only if
the prescription is accompanied by a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed.
This form must be completely filled out noting the details of the adverse reaction
and signed by the prescriber.
In the case of a verbal prescription, the prescriber must satisfy the operator of the
pharmacy or dispensing physician that a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed
has been completed and signed by the prescriber. A written record of this verbal
prescription and the completed Health Canada Side Effect Reporting Form must be
received by the pharmacy prior to claim submission.
Upon receipt, the pharmacist must:
• Fax, submit online or mail the completed and signed form to Health Canada’s
Canada Vigilance Program; and
• Retain his or her copy of the completed and signed Side Effect Reporting
Form.
(ontario.ca, Revision #17; 2026-08-03 ↗)1 brand, same coverage
Ran-Enalapril · DIN 02352249
Manufacturer: Ranbaxy Pharmaceuticals Canada Inc.; listing date 2011-01-07
Daily cost (source): $0.2203
Health Canada: Marketed since 2022-02-15 · brand TARO-ENALAPRIL · ATC C09AA02 ENALAPRIL · form Tablet · route Oral · ingredients ENALAPRIL SODIUM 4 MG · company Sun pharma canada inc · schedule Prescription
Check this DIN again · Health Canada product recordRan-Enalapril: Formulary list price $0.2203/unit (unit not stated in source; not the patient's cost)
Ministry pays: $0.2203 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=83748 · Verify on the e-Formulary ↗ (DIN 02352249)
Source record
DIN 02352249: Ran-Enalapril
Raw flags: chronicUseMed=Y, sec3=Y
Item: 240800105; group id 322; item number 0716; lccId None; manufacturer id RAN
Source form: Tab; strength: 5mg
Recorded listing: General benefit; chronic-use medication (100-day supply rule, dispensing-fee limit)
Source prices (unrounded): $0.2203; ministry $0.2203
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02352249
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=83748
Interchangeable products
Apo-Enalapril · DIN 02019884 · $0.2203
Co Enalapril · DIN 02291886 · $0.2203
Enalapril · DIN 02400669 · $0.2203
Enalapril · DIN 02442965 · $0.2203
Jamp-Enalapril · DIN 02474794 · $0.2203
Mar-Enalapril · DIN 02459469 · $0.2203
Mylan-Enalapril · DIN 02300044 · $0.2203
Ratio-Enalapril · DIN 02299992 · $0.2203
Sandoz Enalapril · DIN 02299941 · $0.2203
Taro-Enalapril · DIN 02300125 · $0.2203
Teva-Enalapril · DIN 02233005 · $0.2203
Vasotec · DIN 00708879 · $0.2203
Shortage status: resolved shortage (ended 2025-05-20); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02352249
Shortage record checked 2026-09-13T08:10:21.292534+00:00
Vasotec · DIN 00708879 · 5mg · tablet
General benefitMarketed · checked 2026-09-02
Write on scriptno code needed
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Savings card: RxHelp ONE lists Vasotec (read 2026-09-10) — brand-name savings card, free; cannot be combined with another card on the same claim.
(rxhelp.ca ↗)1 brand, same coverage
Vasotec · DIN 00708879
Manufacturer: Organon Canada Inc.; listing date 1996-10-01
Daily cost (source): $1.2182
Health Canada: Marketed since 2022-04-11 · brand VASOTEC · ATC C09AA02 ENALAPRIL · form Tablet · route Oral · ingredients ENALAPRIL SODIUM (ENALAPRIL MALEATE) 4 MG · company Organon canada inc. · schedule Prescription
Check this DIN again · Health Canada product recordMinistry pays: $0.2203 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=8111 · Verify on the e-Formulary ↗ (DIN 00708879)
Source record
DIN 00708879: Vasotec
Raw flags: chronicUseMed=Y, sec3=Y
Item: 240800105; group id 322; item number 0716; lccId None; manufacturer id OCI
Source form: Tab; strength: 5mg
Recorded listing: General benefit; chronic-use medication (100-day supply rule, dispensing-fee limit)
Source prices (unrounded): $1.2182; ministry $0.2203
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=00708879
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=8111
Therapeutic Notes (formulary)
** Each tablet is made with 5mg of enalapril maleate that is equivalent to 4mg of enalapril sodium, in the finished tablets.
Interchangeable products
Apo-Enalapril · DIN 02019884 · $0.2203
Co Enalapril · DIN 02291886 · $0.2203
Enalapril · DIN 02400669 · $0.2203
Enalapril · DIN 02442965 · $0.2203
Jamp-Enalapril · DIN 02474794 · $0.2203
Mar-Enalapril · DIN 02459469 · $0.2203
Mylan-Enalapril · DIN 02300044 · $0.2203
Ran-Enalapril · DIN 02352249 · $0.2203
Ratio-Enalapril · DIN 02299992 · $0.2203
Sandoz Enalapril · DIN 02299941 · $0.2203
Taro-Enalapril · DIN 02300125 · $0.2203
Teva-Enalapril · DIN 02233005 · $0.2203
Shortage status: active shortage (reported 2026-06-25, estimated to end 2026-10-09, last updated 2026-06-26); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=00708879
Shortage record checked 2026-09-13T08:10:21.292534+00:00
Apo-Enalapril · DIN 02019892 · 10mg · tablet
General benefitMarketed · checked 2026-09-02
Write on scriptno code needed
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Brand vs generic price
Lowest DBP recovery rule under medically necessary no-substitution claims:
6.2 Medically Necessary "No Substitution" Claims
The Side Effect Reporting Form will not have to be renewed. However, the
pharmacy must maintain a copy of the prescription that contains a direction that
there be no substitution and the required Health Canada Side Effect Reporting Form
(completed and signed by the prescriber). The prescriber must write “No
Substitution” or “No Sub” on renewal or subsequent new written prescriptions, and
indicate “No Substitution” on subsequent new oral prescriptions. The dispenser will
be reimbursed the DBP plus a mark-up and the lesser of the posted usual and
customary fee or the ODB dispensing fee minus the applicable ODB co-payment
amount. Where a completed Side Effect Reporting Form is not available at the
pharmacy during an inspection, the difference between the cost of the higher-cost
product and the lowest DBP listed for the interchangeable category will be
recovered.
(ontario.ca, Revision #17; 2026-08-03 ↗)
6.2 Medically Necessary "No Substitution" Claims
The Ministry will provide reimbursement of a higher-cost interchangeable product in
medically necessary circumstances where a patient has experienced a significant
adverse reaction with two (2) lower-cost interchangeable drug products, where
available. When a prescriber identifies a patient for which it is medically necessary
that a higher cost interchangeable product be provided, the prescriber must:
• Complete, sign and forward to the pharmacist a copy of the Health Canada
side effect reporting form for each lower-cost interchangeable drug product
trialed (Side Effect Reporting Form[s]); and
• Write “No Substitution” or “No Sub” on a written prescription or indicate “No
Substitution” to the pharmacist in the case of a verbal prescription.
The prescriber should keep a copy of the completed form in the patient’s record for
future use and reference.
In the case of a written prescription, when the pharmacist or dispensing physician
receives a prescription with the written notation “No Substitution” or “No Sub”,
reimbursement will be provided for the higher-cost interchangeable product only if
the prescription is accompanied by a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed.
This form must be completely filled out noting the details of the adverse reaction
and signed by the prescriber.
In the case of a verbal prescription, the prescriber must satisfy the operator of the
pharmacy or dispensing physician that a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed
has been completed and signed by the prescriber. A written record of this verbal
prescription and the completed Health Canada Side Effect Reporting Form must be
received by the pharmacy prior to claim submission.
Upon receipt, the pharmacist must:
• Fax, submit online or mail the completed and signed form to Health Canada’s
Canada Vigilance Program; and
• Retain his or her copy of the completed and signed Side Effect Reporting
Form.
(ontario.ca, Revision #17; 2026-08-03 ↗)1 brand, same coverage
Apo-Enalapril · DIN 02019892
Manufacturer: Apotex Inc.; listing date 2007-12-19
Daily cost (source): $0.2647
Health Canada: Marketed since 1993-12-31 · brand APO-ENALAPRIL · ATC C09AA02 ENALAPRIL · form Tablet · route Oral · ingredients ENALAPRIL MALEATE 10 MG · company Apotex inc · schedule Prescription
Check this DIN again · Health Canada product recordApo-Enalapril: Formulary list price $0.2647/unit (unit not stated in source; not the patient's cost)
Ministry pays: $0.2647 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=14387 · Verify on the e-Formulary ↗ (DIN 02019892)
Source record
DIN 02019892: Apo-Enalapril
Raw flags: chronicUseMed=Y, sec3=Y
Item: 240800104; group id 322; item number 0717; lccId None; manufacturer id APX
Source form: Tab; strength: 10mg
Recorded listing: General benefit; chronic-use medication (100-day supply rule, dispensing-fee limit)
Source prices (unrounded): $0.2647; ministry $0.2647
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02019892
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=14387
Interchangeable products
Co Enalapril · DIN 02291894 · $0.2647
Enalapril · DIN 02400677 · $0.2647
Enalapril · DIN 02442973 · $0.2647
Jamp-Enalapril · DIN 02474808 · $0.2647
Mar-Enalapril · DIN 02444771 · $0.2647
Mylan-Enalapril · DIN 02300052 · $0.2647
Ran-Enalapril · DIN 02352257 · $0.2647
Ratio-Enalapril · DIN 02300001 · $0.2647
Sandoz Enalapril · DIN 02299968 · $0.2647
Taro-Enalapril · DIN 02300133 · $0.2647
Teva-Enalapril · DIN 02233006 · $0.2647
Vasotec · DIN 00670901 · $0.2647
Shortage status: resolved shortage (ended 2022-06-28); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02019892
Shortage record checked 2026-09-13T08:10:21.292534+00:00
Co Enalapril · DIN 02291894 · 10mg · tablet
General benefitMarketed · checked 2026-09-02
Write on scriptno code needed
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Brand vs generic price
Lowest DBP recovery rule under medically necessary no-substitution claims:
6.2 Medically Necessary "No Substitution" Claims
The Side Effect Reporting Form will not have to be renewed. However, the
pharmacy must maintain a copy of the prescription that contains a direction that
there be no substitution and the required Health Canada Side Effect Reporting Form
(completed and signed by the prescriber). The prescriber must write “No
Substitution” or “No Sub” on renewal or subsequent new written prescriptions, and
indicate “No Substitution” on subsequent new oral prescriptions. The dispenser will
be reimbursed the DBP plus a mark-up and the lesser of the posted usual and
customary fee or the ODB dispensing fee minus the applicable ODB co-payment
amount. Where a completed Side Effect Reporting Form is not available at the
pharmacy during an inspection, the difference between the cost of the higher-cost
product and the lowest DBP listed for the interchangeable category will be
recovered.
(ontario.ca, Revision #17; 2026-08-03 ↗)
6.2 Medically Necessary "No Substitution" Claims
The Ministry will provide reimbursement of a higher-cost interchangeable product in
medically necessary circumstances where a patient has experienced a significant
adverse reaction with two (2) lower-cost interchangeable drug products, where
available. When a prescriber identifies a patient for which it is medically necessary
that a higher cost interchangeable product be provided, the prescriber must:
• Complete, sign and forward to the pharmacist a copy of the Health Canada
side effect reporting form for each lower-cost interchangeable drug product
trialed (Side Effect Reporting Form[s]); and
• Write “No Substitution” or “No Sub” on a written prescription or indicate “No
Substitution” to the pharmacist in the case of a verbal prescription.
The prescriber should keep a copy of the completed form in the patient’s record for
future use and reference.
In the case of a written prescription, when the pharmacist or dispensing physician
receives a prescription with the written notation “No Substitution” or “No Sub”,
reimbursement will be provided for the higher-cost interchangeable product only if
the prescription is accompanied by a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed.
This form must be completely filled out noting the details of the adverse reaction
and signed by the prescriber.
In the case of a verbal prescription, the prescriber must satisfy the operator of the
pharmacy or dispensing physician that a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed
has been completed and signed by the prescriber. A written record of this verbal
prescription and the completed Health Canada Side Effect Reporting Form must be
received by the pharmacy prior to claim submission.
Upon receipt, the pharmacist must:
• Fax, submit online or mail the completed and signed form to Health Canada’s
Canada Vigilance Program; and
• Retain his or her copy of the completed and signed Side Effect Reporting
Form.
(ontario.ca, Revision #17; 2026-08-03 ↗)1 brand, same coverage
Co Enalapril · DIN 02291894
Manufacturer: Cobalt Pharmaceuticals Company; listing date 2007-12-19
Daily cost (source): $0.2647
Health Canada: Marketed since 2017-08-18 · brand ACT ENALAPRIL · ATC C09AA02 ENALAPRIL · form Tablet · route Oral · ingredients ENALAPRIL SODIUM (ENALAPRIL MALEATE) 8 MG · company Teva canada limited · schedule Prescription
Check this DIN again · Health Canada product recordCo Enalapril: Formulary list price $0.2647/unit (unit not stated in source; not the patient's cost)
Ministry pays: $0.2647 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=77726 · Verify on the e-Formulary ↗ (DIN 02291894)
Source record
DIN 02291894: Co Enalapril
Raw flags: chronicUseMed=Y, sec3=Y
Item: 240800104; group id 322; item number 0717; lccId None; manufacturer id COB
Source form: Tab; strength: 10mg
Recorded listing: General benefit; chronic-use medication (100-day supply rule, dispensing-fee limit)
Source prices (unrounded): $0.2647; ministry $0.2647
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02291894
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=77726
Therapeutic Notes (formulary)
** Each tablet is made with 10mg of enalapril maleate that is equivalent to 8mg of enalapril sodium, in the finished tablets.
Interchangeable products
Apo-Enalapril · DIN 02019892 · $0.2647
Enalapril · DIN 02400677 · $0.2647
Enalapril · DIN 02442973 · $0.2647
Jamp-Enalapril · DIN 02474808 · $0.2647
Mar-Enalapril · DIN 02444771 · $0.2647
Mylan-Enalapril · DIN 02300052 · $0.2647
Ran-Enalapril · DIN 02352257 · $0.2647
Ratio-Enalapril · DIN 02300001 · $0.2647
Sandoz Enalapril · DIN 02299968 · $0.2647
Taro-Enalapril · DIN 02300133 · $0.2647
Teva-Enalapril · DIN 02233006 · $0.2647
Vasotec · DIN 00670901 · $0.2647
Shortage status: discontinued (2017-04-07, reported by TEVA CANADA LIMITED); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02291894
Shortage record checked 2026-09-13T08:10:21.292534+00:00
Enalapril · DIN 02400677 · 10mg · tablet
General benefitMarketed · checked 2026-09-02
Write on scriptno code needed
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Brand vs generic price
Lowest DBP recovery rule under medically necessary no-substitution claims:
6.2 Medically Necessary "No Substitution" Claims
The Side Effect Reporting Form will not have to be renewed. However, the
pharmacy must maintain a copy of the prescription that contains a direction that
there be no substitution and the required Health Canada Side Effect Reporting Form
(completed and signed by the prescriber). The prescriber must write “No
Substitution” or “No Sub” on renewal or subsequent new written prescriptions, and
indicate “No Substitution” on subsequent new oral prescriptions. The dispenser will
be reimbursed the DBP plus a mark-up and the lesser of the posted usual and
customary fee or the ODB dispensing fee minus the applicable ODB co-payment
amount. Where a completed Side Effect Reporting Form is not available at the
pharmacy during an inspection, the difference between the cost of the higher-cost
product and the lowest DBP listed for the interchangeable category will be
recovered.
(ontario.ca, Revision #17; 2026-08-03 ↗)
6.2 Medically Necessary "No Substitution" Claims
The Ministry will provide reimbursement of a higher-cost interchangeable product in
medically necessary circumstances where a patient has experienced a significant
adverse reaction with two (2) lower-cost interchangeable drug products, where
available. When a prescriber identifies a patient for which it is medically necessary
that a higher cost interchangeable product be provided, the prescriber must:
• Complete, sign and forward to the pharmacist a copy of the Health Canada
side effect reporting form for each lower-cost interchangeable drug product
trialed (Side Effect Reporting Form[s]); and
• Write “No Substitution” or “No Sub” on a written prescription or indicate “No
Substitution” to the pharmacist in the case of a verbal prescription.
The prescriber should keep a copy of the completed form in the patient’s record for
future use and reference.
In the case of a written prescription, when the pharmacist or dispensing physician
receives a prescription with the written notation “No Substitution” or “No Sub”,
reimbursement will be provided for the higher-cost interchangeable product only if
the prescription is accompanied by a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed.
This form must be completely filled out noting the details of the adverse reaction
and signed by the prescriber.
In the case of a verbal prescription, the prescriber must satisfy the operator of the
pharmacy or dispensing physician that a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed
has been completed and signed by the prescriber. A written record of this verbal
prescription and the completed Health Canada Side Effect Reporting Form must be
received by the pharmacy prior to claim submission.
Upon receipt, the pharmacist must:
• Fax, submit online or mail the completed and signed form to Health Canada’s
Canada Vigilance Program; and
• Retain his or her copy of the completed and signed Side Effect Reporting
Form.
(ontario.ca, Revision #17; 2026-08-03 ↗)1 brand, same coverage
Enalapril · DIN 02400677
Manufacturer: Sanis Health Inc.; listing date 2022-02-28
Daily cost (source): $0.2647
Health Canada: Marketed since 2022-01-07 · brand ENALAPRIL · ATC C09AA02 ENALAPRIL · form Tablet · route Oral · ingredients ENALAPRIL MALEATE 10 MG · company Sanis health inc · schedule Prescription
Check this DIN again · Health Canada product recordEnalapril: Formulary list price $0.2647/unit (unit not stated in source; not the patient's cost)
Ministry pays: $0.2647 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=88545 · Verify on the e-Formulary ↗ (DIN 02400677)
Source record
DIN 02400677: Enalapril
Raw flags: chronicUseMed=Y, sec3=Y
Item: 240800104; group id 322; item number 0717; lccId None; manufacturer id SAI
Source form: Tab; strength: 10mg
Recorded listing: General benefit; chronic-use medication (100-day supply rule, dispensing-fee limit)
Source prices (unrounded): $0.2647; ministry $0.2647
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02400677
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=88545
Interchangeable products
Apo-Enalapril · DIN 02019892 · $0.2647
Co Enalapril · DIN 02291894 · $0.2647
Enalapril · DIN 02442973 · $0.2647
Jamp-Enalapril · DIN 02474808 · $0.2647
Mar-Enalapril · DIN 02444771 · $0.2647
Mylan-Enalapril · DIN 02300052 · $0.2647
Ran-Enalapril · DIN 02352257 · $0.2647
Ratio-Enalapril · DIN 02300001 · $0.2647
Sandoz Enalapril · DIN 02299968 · $0.2647
Taro-Enalapril · DIN 02300133 · $0.2647
Teva-Enalapril · DIN 02233006 · $0.2647
Vasotec · DIN 00670901 · $0.2647
Shortage status: resolved shortage (ended 2022-01-07); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02400677
Shortage record checked 2026-09-13T08:10:21.292534+00:00
Enalapril · DIN 02442973 · 10mg · tablet
General benefitMarketed · checked 2026-09-02
Write on scriptno code needed
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Brand vs generic price
Lowest DBP recovery rule under medically necessary no-substitution claims:
6.2 Medically Necessary "No Substitution" Claims
The Side Effect Reporting Form will not have to be renewed. However, the
pharmacy must maintain a copy of the prescription that contains a direction that
there be no substitution and the required Health Canada Side Effect Reporting Form
(completed and signed by the prescriber). The prescriber must write “No
Substitution” or “No Sub” on renewal or subsequent new written prescriptions, and
indicate “No Substitution” on subsequent new oral prescriptions. The dispenser will
be reimbursed the DBP plus a mark-up and the lesser of the posted usual and
customary fee or the ODB dispensing fee minus the applicable ODB co-payment
amount. Where a completed Side Effect Reporting Form is not available at the
pharmacy during an inspection, the difference between the cost of the higher-cost
product and the lowest DBP listed for the interchangeable category will be
recovered.
(ontario.ca, Revision #17; 2026-08-03 ↗)
6.2 Medically Necessary "No Substitution" Claims
The Ministry will provide reimbursement of a higher-cost interchangeable product in
medically necessary circumstances where a patient has experienced a significant
adverse reaction with two (2) lower-cost interchangeable drug products, where
available. When a prescriber identifies a patient for which it is medically necessary
that a higher cost interchangeable product be provided, the prescriber must:
• Complete, sign and forward to the pharmacist a copy of the Health Canada
side effect reporting form for each lower-cost interchangeable drug product
trialed (Side Effect Reporting Form[s]); and
• Write “No Substitution” or “No Sub” on a written prescription or indicate “No
Substitution” to the pharmacist in the case of a verbal prescription.
The prescriber should keep a copy of the completed form in the patient’s record for
future use and reference.
In the case of a written prescription, when the pharmacist or dispensing physician
receives a prescription with the written notation “No Substitution” or “No Sub”,
reimbursement will be provided for the higher-cost interchangeable product only if
the prescription is accompanied by a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed.
This form must be completely filled out noting the details of the adverse reaction
and signed by the prescriber.
In the case of a verbal prescription, the prescriber must satisfy the operator of the
pharmacy or dispensing physician that a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed
has been completed and signed by the prescriber. A written record of this verbal
prescription and the completed Health Canada Side Effect Reporting Form must be
received by the pharmacy prior to claim submission.
Upon receipt, the pharmacist must:
• Fax, submit online or mail the completed and signed form to Health Canada’s
Canada Vigilance Program; and
• Retain his or her copy of the completed and signed Side Effect Reporting
Form.
(ontario.ca, Revision #17; 2026-08-03 ↗)1 brand, same coverage
Enalapril · DIN 02442973
Manufacturer: Sivem Pharmaceuticals ULC; listing date 2020-11-30
Daily cost (source): $0.2647
Health Canada: Marketed since 2018-10-04 · brand ENALAPRIL · ATC C09AA02 ENALAPRIL · form Tablet · route Oral · ingredients ENALAPRIL SODIUM (ENALAPRIL MALEATE) 8 MG · company Sivem pharmaceuticals ulc · schedule Prescription
Check this DIN again · Health Canada product recordEnalapril: Formulary list price $0.2647/unit (unit not stated in source; not the patient's cost)
Ministry pays: $0.2647 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=92750 · Verify on the e-Formulary ↗ (DIN 02442973)
Source record
DIN 02442973: Enalapril
Raw flags: chronicUseMed=Y, sec3=Y
Item: 240800104; group id 322; item number 0717; lccId None; manufacturer id SIV
Source form: Tab; strength: 10mg
Recorded listing: General benefit; chronic-use medication (100-day supply rule, dispensing-fee limit)
Source prices (unrounded): $0.2647; ministry $0.2647
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02442973
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=92750
Interchangeable products
Apo-Enalapril · DIN 02019892 · $0.2647
Co Enalapril · DIN 02291894 · $0.2647
Enalapril · DIN 02400677 · $0.2647
Jamp-Enalapril · DIN 02474808 · $0.2647
Mar-Enalapril · DIN 02444771 · $0.2647
Mylan-Enalapril · DIN 02300052 · $0.2647
Ran-Enalapril · DIN 02352257 · $0.2647
Ratio-Enalapril · DIN 02300001 · $0.2647
Sandoz Enalapril · DIN 02299968 · $0.2647
Taro-Enalapril · DIN 02300133 · $0.2647
Teva-Enalapril · DIN 02233006 · $0.2647
Vasotec · DIN 00670901 · $0.2647
Shortage status: resolved shortage (ended 2018-10-19); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02442973
Shortage record checked 2026-09-13T08:10:21.292534+00:00
Jamp-Enalapril · DIN 02474808 · 10mg · tablet
General benefitMarketed · checked 2026-09-02
Write on scriptno code needed
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Brand vs generic price
Lowest DBP recovery rule under medically necessary no-substitution claims:
6.2 Medically Necessary "No Substitution" Claims
The Side Effect Reporting Form will not have to be renewed. However, the
pharmacy must maintain a copy of the prescription that contains a direction that
there be no substitution and the required Health Canada Side Effect Reporting Form
(completed and signed by the prescriber). The prescriber must write “No
Substitution” or “No Sub” on renewal or subsequent new written prescriptions, and
indicate “No Substitution” on subsequent new oral prescriptions. The dispenser will
be reimbursed the DBP plus a mark-up and the lesser of the posted usual and
customary fee or the ODB dispensing fee minus the applicable ODB co-payment
amount. Where a completed Side Effect Reporting Form is not available at the
pharmacy during an inspection, the difference between the cost of the higher-cost
product and the lowest DBP listed for the interchangeable category will be
recovered.
(ontario.ca, Revision #17; 2026-08-03 ↗)
6.2 Medically Necessary "No Substitution" Claims
The Ministry will provide reimbursement of a higher-cost interchangeable product in
medically necessary circumstances where a patient has experienced a significant
adverse reaction with two (2) lower-cost interchangeable drug products, where
available. When a prescriber identifies a patient for which it is medically necessary
that a higher cost interchangeable product be provided, the prescriber must:
• Complete, sign and forward to the pharmacist a copy of the Health Canada
side effect reporting form for each lower-cost interchangeable drug product
trialed (Side Effect Reporting Form[s]); and
• Write “No Substitution” or “No Sub” on a written prescription or indicate “No
Substitution” to the pharmacist in the case of a verbal prescription.
The prescriber should keep a copy of the completed form in the patient’s record for
future use and reference.
In the case of a written prescription, when the pharmacist or dispensing physician
receives a prescription with the written notation “No Substitution” or “No Sub”,
reimbursement will be provided for the higher-cost interchangeable product only if
the prescription is accompanied by a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed.
This form must be completely filled out noting the details of the adverse reaction
and signed by the prescriber.
In the case of a verbal prescription, the prescriber must satisfy the operator of the
pharmacy or dispensing physician that a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed
has been completed and signed by the prescriber. A written record of this verbal
prescription and the completed Health Canada Side Effect Reporting Form must be
received by the pharmacy prior to claim submission.
Upon receipt, the pharmacist must:
• Fax, submit online or mail the completed and signed form to Health Canada’s
Canada Vigilance Program; and
• Retain his or her copy of the completed and signed Side Effect Reporting
Form.
(ontario.ca, Revision #17; 2026-08-03 ↗)1 brand, same coverage
Jamp-Enalapril · DIN 02474808
Manufacturer: Jamp Pharma Corporation; listing date 2019-04-30
Daily cost (source): $0.2647
Health Canada: Marketed since 2019-02-25 · brand JAMP ENALAPRIL · ATC C09AA02 ENALAPRIL · form Tablet · route Oral · ingredients ENALAPRIL MALEATE 10 MG · company Jamp pharma corporation · schedule Prescription
Check this DIN again · Health Canada product recordJamp-Enalapril: Formulary list price $0.2647/unit (unit not stated in source; not the patient's cost)
Ministry pays: $0.2647 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=96499 · Verify on the e-Formulary ↗ (DIN 02474808)
Source record
DIN 02474808: Jamp-Enalapril
Raw flags: chronicUseMed=Y, sec3=Y
Item: 240800104; group id 322; item number 0717; lccId None; manufacturer id JPC
Source form: Tab; strength: 10mg
Recorded listing: General benefit; chronic-use medication (100-day supply rule, dispensing-fee limit)
Source prices (unrounded): $0.2647; ministry $0.2647
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02474808
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=96499
Interchangeable products
Apo-Enalapril · DIN 02019892 · $0.2647
Co Enalapril · DIN 02291894 · $0.2647
Enalapril · DIN 02400677 · $0.2647
Enalapril · DIN 02442973 · $0.2647
Mar-Enalapril · DIN 02444771 · $0.2647
Mylan-Enalapril · DIN 02300052 · $0.2647
Ran-Enalapril · DIN 02352257 · $0.2647
Ratio-Enalapril · DIN 02300001 · $0.2647
Sandoz Enalapril · DIN 02299968 · $0.2647
Taro-Enalapril · DIN 02300133 · $0.2647
Teva-Enalapril · DIN 02233006 · $0.2647
Vasotec · DIN 00670901 · $0.2647
Shortage status: resolved shortage (ended 2024-03-18); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02474808
Shortage record checked 2026-09-13T08:10:21.292534+00:00
Mar-Enalapril · DIN 02444771 · 10mg · tablet
General benefitMarketed · checked 2026-09-02
Write on scriptno code needed
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Brand vs generic price
Lowest DBP recovery rule under medically necessary no-substitution claims:
6.2 Medically Necessary "No Substitution" Claims
The Side Effect Reporting Form will not have to be renewed. However, the
pharmacy must maintain a copy of the prescription that contains a direction that
there be no substitution and the required Health Canada Side Effect Reporting Form
(completed and signed by the prescriber). The prescriber must write “No
Substitution” or “No Sub” on renewal or subsequent new written prescriptions, and
indicate “No Substitution” on subsequent new oral prescriptions. The dispenser will
be reimbursed the DBP plus a mark-up and the lesser of the posted usual and
customary fee or the ODB dispensing fee minus the applicable ODB co-payment
amount. Where a completed Side Effect Reporting Form is not available at the
pharmacy during an inspection, the difference between the cost of the higher-cost
product and the lowest DBP listed for the interchangeable category will be
recovered.
(ontario.ca, Revision #17; 2026-08-03 ↗)
6.2 Medically Necessary "No Substitution" Claims
The Ministry will provide reimbursement of a higher-cost interchangeable product in
medically necessary circumstances where a patient has experienced a significant
adverse reaction with two (2) lower-cost interchangeable drug products, where
available. When a prescriber identifies a patient for which it is medically necessary
that a higher cost interchangeable product be provided, the prescriber must:
• Complete, sign and forward to the pharmacist a copy of the Health Canada
side effect reporting form for each lower-cost interchangeable drug product
trialed (Side Effect Reporting Form[s]); and
• Write “No Substitution” or “No Sub” on a written prescription or indicate “No
Substitution” to the pharmacist in the case of a verbal prescription.
The prescriber should keep a copy of the completed form in the patient’s record for
future use and reference.
In the case of a written prescription, when the pharmacist or dispensing physician
receives a prescription with the written notation “No Substitution” or “No Sub”,
reimbursement will be provided for the higher-cost interchangeable product only if
the prescription is accompanied by a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed.
This form must be completely filled out noting the details of the adverse reaction
and signed by the prescriber.
In the case of a verbal prescription, the prescriber must satisfy the operator of the
pharmacy or dispensing physician that a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed
has been completed and signed by the prescriber. A written record of this verbal
prescription and the completed Health Canada Side Effect Reporting Form must be
received by the pharmacy prior to claim submission.
Upon receipt, the pharmacist must:
• Fax, submit online or mail the completed and signed form to Health Canada’s
Canada Vigilance Program; and
• Retain his or her copy of the completed and signed Side Effect Reporting
Form.
(ontario.ca, Revision #17; 2026-08-03 ↗)1 brand, same coverage
Mar-Enalapril · DIN 02444771
Manufacturer: Marcan Pharmaceuticals Inc.; listing date 2019-06-28
Daily cost (source): $0.2647
Health Canada: Marketed since 2019-03-20 · brand MAR-ENALAPRIL · ATC C09AA02 ENALAPRIL · form Tablet · route Oral · ingredients ENALAPRIL MALEATE 10 MG · company Marcan pharmaceuticals inc · schedule Prescription
Check this DIN again · Health Canada product recordMar-Enalapril: Formulary list price $0.2647/unit (unit not stated in source; not the patient's cost)
Ministry pays: $0.2647 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=92998 · Verify on the e-Formulary ↗ (DIN 02444771)
Source record
DIN 02444771: Mar-Enalapril
Raw flags: chronicUseMed=Y, sec3=Y
Item: 240800104; group id 322; item number 0717; lccId None; manufacturer id MAR
Source form: Tab; strength: 10mg
Recorded listing: General benefit; chronic-use medication (100-day supply rule, dispensing-fee limit)
Source prices (unrounded): $0.2647; ministry $0.2647
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02444771
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=92998
Interchangeable products
Apo-Enalapril · DIN 02019892 · $0.2647
Co Enalapril · DIN 02291894 · $0.2647
Enalapril · DIN 02400677 · $0.2647
Enalapril · DIN 02442973 · $0.2647
Jamp-Enalapril · DIN 02474808 · $0.2647
Mylan-Enalapril · DIN 02300052 · $0.2647
Ran-Enalapril · DIN 02352257 · $0.2647
Ratio-Enalapril · DIN 02300001 · $0.2647
Sandoz Enalapril · DIN 02299968 · $0.2647
Taro-Enalapril · DIN 02300133 · $0.2647
Teva-Enalapril · DIN 02233006 · $0.2647
Vasotec · DIN 00670901 · $0.2647
Shortage status: no shortage or discontinuation reported (checked 2026-09-13T08:10:21.292534+00:00); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02444771
Shortage record checked 2026-09-13T08:10:21.292534+00:00
Ran-Enalapril · DIN 02352257 · 10mg · tablet
General benefitMarketed · checked 2026-09-02
Write on scriptno code needed
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Brand vs generic price
Lowest DBP recovery rule under medically necessary no-substitution claims:
6.2 Medically Necessary "No Substitution" Claims
The Side Effect Reporting Form will not have to be renewed. However, the
pharmacy must maintain a copy of the prescription that contains a direction that
there be no substitution and the required Health Canada Side Effect Reporting Form
(completed and signed by the prescriber). The prescriber must write “No
Substitution” or “No Sub” on renewal or subsequent new written prescriptions, and
indicate “No Substitution” on subsequent new oral prescriptions. The dispenser will
be reimbursed the DBP plus a mark-up and the lesser of the posted usual and
customary fee or the ODB dispensing fee minus the applicable ODB co-payment
amount. Where a completed Side Effect Reporting Form is not available at the
pharmacy during an inspection, the difference between the cost of the higher-cost
product and the lowest DBP listed for the interchangeable category will be
recovered.
(ontario.ca, Revision #17; 2026-08-03 ↗)
6.2 Medically Necessary "No Substitution" Claims
The Ministry will provide reimbursement of a higher-cost interchangeable product in
medically necessary circumstances where a patient has experienced a significant
adverse reaction with two (2) lower-cost interchangeable drug products, where
available. When a prescriber identifies a patient for which it is medically necessary
that a higher cost interchangeable product be provided, the prescriber must:
• Complete, sign and forward to the pharmacist a copy of the Health Canada
side effect reporting form for each lower-cost interchangeable drug product
trialed (Side Effect Reporting Form[s]); and
• Write “No Substitution” or “No Sub” on a written prescription or indicate “No
Substitution” to the pharmacist in the case of a verbal prescription.
The prescriber should keep a copy of the completed form in the patient’s record for
future use and reference.
In the case of a written prescription, when the pharmacist or dispensing physician
receives a prescription with the written notation “No Substitution” or “No Sub”,
reimbursement will be provided for the higher-cost interchangeable product only if
the prescription is accompanied by a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed.
This form must be completely filled out noting the details of the adverse reaction
and signed by the prescriber.
In the case of a verbal prescription, the prescriber must satisfy the operator of the
pharmacy or dispensing physician that a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed
has been completed and signed by the prescriber. A written record of this verbal
prescription and the completed Health Canada Side Effect Reporting Form must be
received by the pharmacy prior to claim submission.
Upon receipt, the pharmacist must:
• Fax, submit online or mail the completed and signed form to Health Canada’s
Canada Vigilance Program; and
• Retain his or her copy of the completed and signed Side Effect Reporting
Form.
(ontario.ca, Revision #17; 2026-08-03 ↗)1 brand, same coverage
Ran-Enalapril · DIN 02352257
Manufacturer: Ranbaxy Pharmaceuticals Canada Inc.; listing date 2011-01-07
Daily cost (source): $0.2647
Health Canada: Marketed since 2022-02-15 · brand TARO-ENALAPRIL · ATC C09AA02 ENALAPRIL · form Tablet · route Oral · ingredients ENALAPRIL SODIUM 8 MG · company Sun pharma canada inc · schedule Prescription
Check this DIN again · Health Canada product recordRan-Enalapril: Formulary list price $0.2647/unit (unit not stated in source; not the patient's cost)
Ministry pays: $0.2647 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=83749 · Verify on the e-Formulary ↗ (DIN 02352257)
Source record
DIN 02352257: Ran-Enalapril
Raw flags: chronicUseMed=Y, sec3=Y
Item: 240800104; group id 322; item number 0717; lccId None; manufacturer id RAN
Source form: Tab; strength: 10mg
Recorded listing: General benefit; chronic-use medication (100-day supply rule, dispensing-fee limit)
Source prices (unrounded): $0.2647; ministry $0.2647
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02352257
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=83749
Interchangeable products
Apo-Enalapril · DIN 02019892 · $0.2647
Co Enalapril · DIN 02291894 · $0.2647
Enalapril · DIN 02400677 · $0.2647
Enalapril · DIN 02442973 · $0.2647
Jamp-Enalapril · DIN 02474808 · $0.2647
Mar-Enalapril · DIN 02444771 · $0.2647
Mylan-Enalapril · DIN 02300052 · $0.2647
Ratio-Enalapril · DIN 02300001 · $0.2647
Sandoz Enalapril · DIN 02299968 · $0.2647
Taro-Enalapril · DIN 02300133 · $0.2647
Teva-Enalapril · DIN 02233006 · $0.2647
Vasotec · DIN 00670901 · $0.2647
Shortage status: resolved shortage (ended 2023-11-04); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02352257
Shortage record checked 2026-09-13T08:10:21.292534+00:00
Vasotec · DIN 00670901 · 10mg · tablet
General benefitMarketed · checked 2026-09-02
Write on scriptno code needed
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Savings card: RxHelp ONE lists Vasotec (read 2026-09-10) — brand-name savings card, free; cannot be combined with another card on the same claim.
(rxhelp.ca ↗)1 brand, same coverage
Vasotec · DIN 00670901
Manufacturer: Organon Canada Inc.; listing date 1996-10-01
Daily cost (source): $1.4638
Health Canada: Marketed since 2022-04-07 · brand VASOTEC · ATC C09AA02 ENALAPRIL · form Tablet · route Oral · ingredients ENALAPRIL SODIUM (ENALAPRIL MALEATE) 8 MG · company Organon canada inc. · schedule Prescription
Check this DIN again · Health Canada product recordMinistry pays: $0.2647 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=8102 · Verify on the e-Formulary ↗ (DIN 00670901)
Source record
DIN 00670901: Vasotec
Raw flags: chronicUseMed=Y, sec3=Y
Item: 240800104; group id 322; item number 0717; lccId None; manufacturer id OCI
Source form: Tab; strength: 10mg
Recorded listing: General benefit; chronic-use medication (100-day supply rule, dispensing-fee limit)
Source prices (unrounded): $1.4638; ministry $0.2647
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=00670901
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=8102
Therapeutic Notes (formulary)
** Each tablet is made with 10mg of enalapril maleate that is equivalent to 8mg of enalapril sodium, in the finished tablets.
Interchangeable products
Apo-Enalapril · DIN 02019892 · $0.2647
Co Enalapril · DIN 02291894 · $0.2647
Enalapril · DIN 02400677 · $0.2647
Enalapril · DIN 02442973 · $0.2647
Jamp-Enalapril · DIN 02474808 · $0.2647
Mar-Enalapril · DIN 02444771 · $0.2647
Mylan-Enalapril · DIN 02300052 · $0.2647
Ran-Enalapril · DIN 02352257 · $0.2647
Ratio-Enalapril · DIN 02300001 · $0.2647
Sandoz Enalapril · DIN 02299968 · $0.2647
Taro-Enalapril · DIN 02300133 · $0.2647
Teva-Enalapril · DIN 02233006 · $0.2647
Shortage status: resolved shortage (ended 2024-09-12); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=00670901
Shortage record checked 2026-09-13T08:10:21.292534+00:00
Apo-Enalapril · DIN 02019906 · 20mg · tablet
General benefitMarketed · checked 2026-09-02
Write on scriptno code needed
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Brand vs generic price
Lowest DBP recovery rule under medically necessary no-substitution claims:
6.2 Medically Necessary "No Substitution" Claims
The Side Effect Reporting Form will not have to be renewed. However, the
pharmacy must maintain a copy of the prescription that contains a direction that
there be no substitution and the required Health Canada Side Effect Reporting Form
(completed and signed by the prescriber). The prescriber must write “No
Substitution” or “No Sub” on renewal or subsequent new written prescriptions, and
indicate “No Substitution” on subsequent new oral prescriptions. The dispenser will
be reimbursed the DBP plus a mark-up and the lesser of the posted usual and
customary fee or the ODB dispensing fee minus the applicable ODB co-payment
amount. Where a completed Side Effect Reporting Form is not available at the
pharmacy during an inspection, the difference between the cost of the higher-cost
product and the lowest DBP listed for the interchangeable category will be
recovered.
(ontario.ca, Revision #17; 2026-08-03 ↗)
6.2 Medically Necessary "No Substitution" Claims
The Ministry will provide reimbursement of a higher-cost interchangeable product in
medically necessary circumstances where a patient has experienced a significant
adverse reaction with two (2) lower-cost interchangeable drug products, where
available. When a prescriber identifies a patient for which it is medically necessary
that a higher cost interchangeable product be provided, the prescriber must:
• Complete, sign and forward to the pharmacist a copy of the Health Canada
side effect reporting form for each lower-cost interchangeable drug product
trialed (Side Effect Reporting Form[s]); and
• Write “No Substitution” or “No Sub” on a written prescription or indicate “No
Substitution” to the pharmacist in the case of a verbal prescription.
The prescriber should keep a copy of the completed form in the patient’s record for
future use and reference.
In the case of a written prescription, when the pharmacist or dispensing physician
receives a prescription with the written notation “No Substitution” or “No Sub”,
reimbursement will be provided for the higher-cost interchangeable product only if
the prescription is accompanied by a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed.
This form must be completely filled out noting the details of the adverse reaction
and signed by the prescriber.
In the case of a verbal prescription, the prescriber must satisfy the operator of the
pharmacy or dispensing physician that a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed
has been completed and signed by the prescriber. A written record of this verbal
prescription and the completed Health Canada Side Effect Reporting Form must be
received by the pharmacy prior to claim submission.
Upon receipt, the pharmacist must:
• Fax, submit online or mail the completed and signed form to Health Canada’s
Canada Vigilance Program; and
• Retain his or her copy of the completed and signed Side Effect Reporting
Form.
(ontario.ca, Revision #17; 2026-08-03 ↗)1 brand, same coverage
Apo-Enalapril · DIN 02019906
Manufacturer: Apotex Inc.; listing date 2007-12-19
Daily cost (source): $0.3195
Health Canada: Marketed since 1993-12-31 · brand APO-ENALAPRIL · ATC C09AA02 ENALAPRIL · form Tablet · route Oral · ingredients ENALAPRIL MALEATE 20 MG · company Apotex inc · schedule Prescription
Check this DIN again · Health Canada product recordApo-Enalapril: Formulary list price $0.3195/unit (unit not stated in source; not the patient's cost)
Ministry pays: $0.3195 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=14388 · Verify on the e-Formulary ↗ (DIN 02019906)
Source record
DIN 02019906: Apo-Enalapril
Raw flags: chronicUseMed=Y, sec3=Y
Item: 240800103; group id 322; item number 0718; lccId None; manufacturer id APX
Source form: Tab; strength: 20mg
Recorded listing: General benefit; chronic-use medication (100-day supply rule, dispensing-fee limit)
Source prices (unrounded): $0.3195; ministry $0.3195
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02019906
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=14388
Interchangeable products
Co Enalapril · DIN 02291908 · $0.3195
Enalapril · DIN 02400685 · $0.3195
Enalapril · DIN 02442981 · $0.3195
Jamp-Enalapril · DIN 02474816 · $0.3195
Mar-Enalapril · DIN 02444798 · $0.3195
Mylan-Enalapril · DIN 02300060 · $0.3195
Ran-Enalapril · DIN 02352265 · $0.3195
Ratio-Enalapril · DIN 02300028 · $0.3195
Sandoz Enalapril · DIN 02299976 · $0.3195
Taro-Enalapril · DIN 02300141 · $0.3195
Teva-Enalapril · DIN 02233007 · $0.3195
Vasotec · DIN 00670928 · $0.3195
Shortage status: resolved shortage (ended 2023-12-21); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02019906
Shortage record checked 2026-09-13T08:10:21.292534+00:00
Other drugs in the same formulary class (24:08 Hypotensive Drugs (For Diuretics See 40:28)) and how they are covered
Matched class: 24:08 Hypotensive Drugs (For Diuretics See 40:28)
Drug-class inventory only. Lists recorded Ontario formulary products, not every Canadian medication; does not recommend treatment.
Covered without a code on the Ontario formulary: CANDESARTAN CILEXETIL, CANDESARTAN CILEXETIL & HYDROCHLOROTHIAZIDE, CILAZAPRIL & HYDROCHLOROTHIAZIDE, LABETALOL HCL, LOSARTAN POTASSIUM, LOSARTAN POTASSIUM & HYDROCHLOROTHIAZIDE, MINOXIDIL, OLMESARTAN MEDOXOMIL, OLMESARTAN MEDOXOMIL & HYDROCHLOROTHIAZIDE, PERINDOPRIL ERBUMINE, PERINDOPRIL ERBUMINE & INDAPAMIDE, PINDOLOL & HYDROCHLOROTHIAZIDE, TELMISARTAN, TELMISARTAN & AMLODIPINE BESYLATE, TELMISARTAN & HYDROCHLOROTHIAZIDE, VALSARTAN & HYDROCHLOROTHIAZIDE
Some products covered without a code (check the product listing): ATENOLOL & CHLORTHALIDONE, BENAZEPRIL, CAPTOPRIL, CILAZAPRIL, CLONIDINE HCL, DOXAZOSIN MESYLATE, FELODIPINE, FOSINOPRIL SODIUM, HYDRALAZINE HCL, IRBESARTAN, IRBESARTAN & HYDROCHLOROTHIAZIDE, LISINOPRIL, LISINOPRIL & HYDROCHLOROTHIAZIDE, METHYLDOPA, NIFEDIPINE, PINDOLOL, PRAZOSIN HCL, QUINAPRIL, QUINAPRIL & HYDROCHLOROTHIAZIDE, RAMIPRIL, RAMIPRIL & HYDROCHLOROTHIAZIDE, TERAZOSIN HCL, TRANDOLAPRIL, VALSARTAN, VERAPAMIL HCL
24:08 Hypotensive Drugs (For Diuretics See 40:28)
· 6 products · Listed, not a benefit (3), General benefit (3) · strengths: 5mg, 10mg, 20mg · Tab
· 14 products ·
Limited Use, codes 707, 723 (2), Listed, not a benefit (4), General benefit (8) · strengths: 5mg/5mL, 25mg/5mL, 12.5mg, 25mg, 50mg, 100mg · Oral Sol, Tab
· 8 products · Listed, not a benefit (2), General benefit (6) · strengths: 1mg, 2.5mg, 5mg · Tab
· 12 products · Listed, not a benefit (2), General benefit (10) · strengths: 10mg, 20mg · Tab
· 45 products · Listed, not a benefit (1), General benefit (44) · strengths: 5mg, 10mg, 20mg · Tab
· 45 products · General benefit · strengths: 2mg, 4mg, 8mg · Tab
· 12 products · Listed, not a benefit (4), General benefit (8) · strengths: 5mg, 10mg, 20mg, 40mg · Tab
· 67 products · General benefit (57), Listed, not a benefit (4), Off-Formulary Interchangeable, not an ODB benefit (6) · strengths: 1.25mg, 2.5mg, 5mg, 10mg, 15mg · Cap
· 26 products · Off-Formulary Interchangeable, not an ODB benefit (5), General benefit (21) · strengths: 0.5mg, 1mg, 2mg, 4mg · Cap
· 4 products · Listed, not a benefit (2), General benefit (2) · strengths: 50 & 25mg, 100 & 25mg · Tab
· 59 products · General benefit · strengths: 4mg, 8mg, 16mg, 32mg · Tab
· 21 products · General benefit · strengths: 16mg & 12.5mg, 32mg & 12.5mg, 32mg & 25mg · Tab
Source: formulary-ed43-front-matter.txt Part V; ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26; class 24:08
and 34 more
Full class listing
Related classes: 24:04 Cardiac Drugs, 24:06 Antilipemic Drugs, 24:12 Vasodilating Drugs, 24:32 Renin-Angiotensin Aldosterone Inhibitors
Same formulary class, not same indication: class membership alone does not establish equivalent uses.