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Lowest DBP recovery rule under medically necessary no-substitution claims: 6.2 Medically Necessary "No Substitution" Claims The Side Effect Reporting Form will not have to be renewed. However, the pharmacy must maintain a copy of the prescription that contains a direction that there be no substitution and the required Health Canada Side Effect Reporting Form (completed and signed by the prescriber). The prescriber must write “No Substitution” or “No Sub” on renewal or subsequent new written prescriptions, and indicate “No Substitution” on subsequent new oral prescriptions. The dispenser will be reimbursed the DBP plus a mark-up and the lesser of the posted usual and customary fee or the ODB dispensing fee minus the applicable ODB co-payment amount. Where a completed Side Effect Reporting Form is not available at the pharmacy during an inspection, the difference between the cost of the higher-cost product and the lowest DBP listed for the interchangeable category will be recovered. (ontario.ca, Revision #17; 2026-08-03 ↗) 6.2 Medically Necessary "No Substitution" Claims The Ministry will provide reimbursement of a higher-cost interchangeable product in medically necessary circumstances where a patient has experienced a significant adverse reaction with two (2) lower-cost interchangeable drug products, where available. When a prescriber identifies a patient for which it is medically necessary that a higher cost interchangeable product be provided, the prescriber must: • Complete, sign and forward to the pharmacist a copy of the Health Canada side effect reporting form for each lower-cost interchangeable drug product trialed (Side Effect Reporting Form[s]); and • Write “No Substitution” or “No Sub” on a written prescription or indicate “No Substitution” to the pharmacist in the case of a verbal prescription. The prescriber should keep a copy of the completed form in the patient’s record for future use and reference. In the case of a written prescription, when the pharmacist or dispensing physician receives a prescription with the written notation “No Substitution” or “No Sub”, reimbursement will be provided for the higher-cost interchangeable product only if the prescription is accompanied by a completed Health Canada Side Effect Reporting Form for each of the lower-cost interchangeable drug products trialed. This form must be completely filled out noting the details of the adverse reaction and signed by the prescriber. In the case of a verbal prescription, the prescriber must satisfy the operator of the pharmacy or dispensing physician that a completed Health Canada Side Effect Reporting Form for each of the lower-cost interchangeable drug products trialed has been completed and signed by the prescriber. A written record of this verbal prescription and the completed Health Canada Side Effect Reporting Form must be received by the pharmacy prior to claim submission. Upon receipt, the pharmacist must: • Fax, submit online or mail the completed and signed form to Health Canada’s Canada Vigilance Program; and • Retain his or her copy of the completed and signed Side Effect Reporting Form. (ontario.ca, Revision #17; 2026-08-03 ↗)

Co Pregabalin · DIN 02402912 Manufacturer: Cobalt Pharmaceuticals Company; listing date 2013-04-30 Health Canada: Cancelled post market since 2019-07-09 · brand ACT PREGABALIN · ATC N02BF02 PREGABALIN · form Capsule · route Oral · ingredients PREGABALIN 25 MG · company Actavis pharma company · schedule Prescription

DIN 02402912: Co Pregabalin Raw flags: sec3=Y Item: 281200094; group id 442; item number 1103; lccId None; manufacturer id COB Source form: Cap; strength: 25mg Recorded listing: General benefit Source prices (unrounded): $0.1481; ministry $0.1481 Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02402912 Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=88774

Interchangeable products

AG-Pregabalin · DIN 02480727 · $0.1481 Ach-Pregabalin · DIN 02449838 · $0.1481 Apo-Pregabalin · DIN 02394235 · $0.1481 Auro-Pregabalin · DIN 02433869 · $0.1481 Bio-Pregabalin · DIN 02541122 · $0.1481 Jamp-Pregabalin · DIN 02435977 · $0.1481 Lyrica · DIN 02268418 · $0.1481 M-Pregabalin · DIN 02467291 · $0.1481 Mar-Pregabalin · DIN 02417529 · $0.1481 Mint-Pregabalin · DIN 02423804 · $0.1481 NRA-Pregabalin · DIN 02479117 · $0.1481 Nat-Pregabalin · DIN 02494841 · $0.1481 PMS-Pregabalin · DIN 02359596 · $0.1481 Pregabalin · DIN 02403692 · $0.1481 Pregabalin · DIN 02405539 · $0.1481 Ran-Pregabalin · DIN 02392801 · $0.1481 Sandoz Pregabalin · DIN 02390817 · $0.1481 Teva-Pregabalin · DIN 02361159 · $0.1481

Shortage status: discontinued (2018-04-30, reported by ACTAVIS PHARMA COMPANY); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada) Source: https://healthproductshortages.ca/search?term=02402912

Shortage record checked 2026-09-13T08:10:21.292534+00:00

Health Canada lists this DIN as Cancelled post market since 2019-07-09 — choose a marketed DIN from the same-category list.