LAMOTRIGINE
All strengths: General benefit; same patient cost rules
Shared coverage and patient cost rules
StatusGeneral benefit
Patient paysPatient pays: program not supplied; amount cannot be determined.
Other products in the same Health Canada class (N03AX) — coverage varies; not interchangeable
- Topiramate (Topamax Sprinkle): general benefit, Limited Use 321, Not a benefit
- Brivaracetam (Brivlera): limited Use 548
- Cenobamate (Xcopri): limited Use 719
- Lacosamide (Vimpat): limited Use 430
- Levetiracetam (PDP-Levetiracetam): limited Use 473, Limited Use 640, 705
- Perampanel (Fycompa): limited Use 430, 564
14 more in the class list below
Apo-Lamotrigine · DIN 02245208 · 25mg · tablet
General benefitMarketed · checked 2026-09-02
Write on scriptno code needed
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Brand vs generic price
Lowest DBP recovery rule under medically necessary no-substitution claims:
6.2 Medically Necessary "No Substitution" Claims
The Side Effect Reporting Form will not have to be renewed. However, the
pharmacy must maintain a copy of the prescription that contains a direction that
there be no substitution and the required Health Canada Side Effect Reporting Form
(completed and signed by the prescriber). The prescriber must write “No
Substitution” or “No Sub” on renewal or subsequent new written prescriptions, and
indicate “No Substitution” on subsequent new oral prescriptions. The dispenser will
be reimbursed the DBP plus a mark-up and the lesser of the posted usual and
customary fee or the ODB dispensing fee minus the applicable ODB co-payment
amount. Where a completed Side Effect Reporting Form is not available at the
pharmacy during an inspection, the difference between the cost of the higher-cost
product and the lowest DBP listed for the interchangeable category will be
recovered.
(ontario.ca, Revision #17; 2026-08-03 ↗)
6.2 Medically Necessary "No Substitution" Claims
The Ministry will provide reimbursement of a higher-cost interchangeable product in
medically necessary circumstances where a patient has experienced a significant
adverse reaction with two (2) lower-cost interchangeable drug products, where
available. When a prescriber identifies a patient for which it is medically necessary
that a higher cost interchangeable product be provided, the prescriber must:
• Complete, sign and forward to the pharmacist a copy of the Health Canada
side effect reporting form for each lower-cost interchangeable drug product
trialed (Side Effect Reporting Form[s]); and
• Write “No Substitution” or “No Sub” on a written prescription or indicate “No
Substitution” to the pharmacist in the case of a verbal prescription.
The prescriber should keep a copy of the completed form in the patient’s record for
future use and reference.
In the case of a written prescription, when the pharmacist or dispensing physician
receives a prescription with the written notation “No Substitution” or “No Sub”,
reimbursement will be provided for the higher-cost interchangeable product only if
the prescription is accompanied by a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed.
This form must be completely filled out noting the details of the adverse reaction
and signed by the prescriber.
In the case of a verbal prescription, the prescriber must satisfy the operator of the
pharmacy or dispensing physician that a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed
has been completed and signed by the prescriber. A written record of this verbal
prescription and the completed Health Canada Side Effect Reporting Form must be
received by the pharmacy prior to claim submission.
Upon receipt, the pharmacist must:
• Fax, submit online or mail the completed and signed form to Health Canada’s
Canada Vigilance Program; and
• Retain his or her copy of the completed and signed Side Effect Reporting
Form.
(ontario.ca, Revision #17; 2026-08-03 ↗)1 brand, same coverage
Apo-Lamotrigine · DIN 02245208
Manufacturer: Apotex Inc.; listing date 2003-01-30
Health Canada: Marketed since 2002-03-18 · brand APO-LAMOTRIGINE · ATC N03AX09 LAMOTRIGINE · form Tablet · route Oral · ingredients LAMOTRIGINE 25 MG · company Apotex inc · schedule Prescription
Check this DIN again · Health Canada product recordApo-Lamotrigine: Formulary list price $0.0698/unit (unit not stated in source; not the patient's cost)
Ministry pays: $0.0698 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=69223 · Verify on the e-Formulary ↗ (DIN 02245208)
Source record
DIN 02245208: Apo-Lamotrigine
Raw flags: sec3=Y
Item: 281200055; group id 432; item number 1079; lccId None; manufacturer id APX
Source form: Tab; strength: 25mg
Recorded listing: General benefit
Source prices (unrounded): $0.0698; ministry $0.0698
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02245208
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=69223
Interchangeable products
Auro-Lamotrigine · DIN 02381354 · $0.0698
Jamp Lamotrigine · DIN 02542730 · $0.0698
Lamictal · DIN 02142082 · $0.0698
Lamotrigine · DIN 02343010 · $0.0698
Lamotrigine · DIN 02428202 · $0.0698
Mylan-Lamotrigine · DIN 02265494 · $0.0698
PMS-Lamotrigine · DIN 02246897 · $0.0698
Ratio-Lamotrigine · DIN 02243352 · $0.0698
Teva-Lamotrigine · DIN 02248232 · $0.0698
Shortage status: resolved shortage (ended 2020-01-27); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02245208
Shortage record checked 2026-09-13T08:10:21.292534+00:00
Auro-Lamotrigine · DIN 02381354 · 25mg · tablet
General benefitMarketed · checked 2026-09-02
Write on scriptno code needed
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Brand vs generic price
Lowest DBP recovery rule under medically necessary no-substitution claims:
6.2 Medically Necessary "No Substitution" Claims
The Side Effect Reporting Form will not have to be renewed. However, the
pharmacy must maintain a copy of the prescription that contains a direction that
there be no substitution and the required Health Canada Side Effect Reporting Form
(completed and signed by the prescriber). The prescriber must write “No
Substitution” or “No Sub” on renewal or subsequent new written prescriptions, and
indicate “No Substitution” on subsequent new oral prescriptions. The dispenser will
be reimbursed the DBP plus a mark-up and the lesser of the posted usual and
customary fee or the ODB dispensing fee minus the applicable ODB co-payment
amount. Where a completed Side Effect Reporting Form is not available at the
pharmacy during an inspection, the difference between the cost of the higher-cost
product and the lowest DBP listed for the interchangeable category will be
recovered.
(ontario.ca, Revision #17; 2026-08-03 ↗)
6.2 Medically Necessary "No Substitution" Claims
The Ministry will provide reimbursement of a higher-cost interchangeable product in
medically necessary circumstances where a patient has experienced a significant
adverse reaction with two (2) lower-cost interchangeable drug products, where
available. When a prescriber identifies a patient for which it is medically necessary
that a higher cost interchangeable product be provided, the prescriber must:
• Complete, sign and forward to the pharmacist a copy of the Health Canada
side effect reporting form for each lower-cost interchangeable drug product
trialed (Side Effect Reporting Form[s]); and
• Write “No Substitution” or “No Sub” on a written prescription or indicate “No
Substitution” to the pharmacist in the case of a verbal prescription.
The prescriber should keep a copy of the completed form in the patient’s record for
future use and reference.
In the case of a written prescription, when the pharmacist or dispensing physician
receives a prescription with the written notation “No Substitution” or “No Sub”,
reimbursement will be provided for the higher-cost interchangeable product only if
the prescription is accompanied by a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed.
This form must be completely filled out noting the details of the adverse reaction
and signed by the prescriber.
In the case of a verbal prescription, the prescriber must satisfy the operator of the
pharmacy or dispensing physician that a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed
has been completed and signed by the prescriber. A written record of this verbal
prescription and the completed Health Canada Side Effect Reporting Form must be
received by the pharmacy prior to claim submission.
Upon receipt, the pharmacist must:
• Fax, submit online or mail the completed and signed form to Health Canada’s
Canada Vigilance Program; and
• Retain his or her copy of the completed and signed Side Effect Reporting
Form.
(ontario.ca, Revision #17; 2026-08-03 ↗)1 brand, same coverage
Auro-Lamotrigine · DIN 02381354
Manufacturer: Auro Pharma Inc.; listing date 2012-08-27
Health Canada: Marketed since 2012-06-13 · brand AURO-LAMOTRIGINE · ATC N03AX09 LAMOTRIGINE · form Tablet · route Oral · ingredients LAMOTRIGINE 25 MG · company Auro pharma inc · schedule Prescription
Check this DIN again · Health Canada product recordAuro-Lamotrigine: Formulary list price $0.0698/unit (unit not stated in source; not the patient's cost)
Ministry pays: $0.0698 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=86718 · Verify on the e-Formulary ↗ (DIN 02381354)
Source record
DIN 02381354: Auro-Lamotrigine
Raw flags: sec3=Y
Item: 281200055; group id 432; item number 1079; lccId None; manufacturer id AUR
Source form: Tab; strength: 25mg
Recorded listing: General benefit
Source prices (unrounded): $0.0698; ministry $0.0698
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02381354
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=86718
Interchangeable products
Apo-Lamotrigine · DIN 02245208 · $0.0698
Jamp Lamotrigine · DIN 02542730 · $0.0698
Lamictal · DIN 02142082 · $0.0698
Lamotrigine · DIN 02343010 · $0.0698
Lamotrigine · DIN 02428202 · $0.0698
Mylan-Lamotrigine · DIN 02265494 · $0.0698
PMS-Lamotrigine · DIN 02246897 · $0.0698
Ratio-Lamotrigine · DIN 02243352 · $0.0698
Teva-Lamotrigine · DIN 02248232 · $0.0698
Shortage status: resolved shortage (ended 2024-08-27); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02381354
Shortage record checked 2026-09-13T08:10:21.292534+00:00
Jamp Lamotrigine · DIN 02542730 · 25mg · tablet
General benefitMarketed · checked 2026-09-02
Write on scriptno code needed
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Brand vs generic price
Lowest DBP recovery rule under medically necessary no-substitution claims:
6.2 Medically Necessary "No Substitution" Claims
The Side Effect Reporting Form will not have to be renewed. However, the
pharmacy must maintain a copy of the prescription that contains a direction that
there be no substitution and the required Health Canada Side Effect Reporting Form
(completed and signed by the prescriber). The prescriber must write “No
Substitution” or “No Sub” on renewal or subsequent new written prescriptions, and
indicate “No Substitution” on subsequent new oral prescriptions. The dispenser will
be reimbursed the DBP plus a mark-up and the lesser of the posted usual and
customary fee or the ODB dispensing fee minus the applicable ODB co-payment
amount. Where a completed Side Effect Reporting Form is not available at the
pharmacy during an inspection, the difference between the cost of the higher-cost
product and the lowest DBP listed for the interchangeable category will be
recovered.
(ontario.ca, Revision #17; 2026-08-03 ↗)
6.2 Medically Necessary "No Substitution" Claims
The Ministry will provide reimbursement of a higher-cost interchangeable product in
medically necessary circumstances where a patient has experienced a significant
adverse reaction with two (2) lower-cost interchangeable drug products, where
available. When a prescriber identifies a patient for which it is medically necessary
that a higher cost interchangeable product be provided, the prescriber must:
• Complete, sign and forward to the pharmacist a copy of the Health Canada
side effect reporting form for each lower-cost interchangeable drug product
trialed (Side Effect Reporting Form[s]); and
• Write “No Substitution” or “No Sub” on a written prescription or indicate “No
Substitution” to the pharmacist in the case of a verbal prescription.
The prescriber should keep a copy of the completed form in the patient’s record for
future use and reference.
In the case of a written prescription, when the pharmacist or dispensing physician
receives a prescription with the written notation “No Substitution” or “No Sub”,
reimbursement will be provided for the higher-cost interchangeable product only if
the prescription is accompanied by a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed.
This form must be completely filled out noting the details of the adverse reaction
and signed by the prescriber.
In the case of a verbal prescription, the prescriber must satisfy the operator of the
pharmacy or dispensing physician that a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed
has been completed and signed by the prescriber. A written record of this verbal
prescription and the completed Health Canada Side Effect Reporting Form must be
received by the pharmacy prior to claim submission.
Upon receipt, the pharmacist must:
• Fax, submit online or mail the completed and signed form to Health Canada’s
Canada Vigilance Program; and
• Retain his or her copy of the completed and signed Side Effect Reporting
Form.
(ontario.ca, Revision #17; 2026-08-03 ↗)1 brand, same coverage
Jamp Lamotrigine · DIN 02542730
Manufacturer: Jamp Pharma Corporation; listing date 2024-08-30
Health Canada: Marketed since 2024-06-21 · brand JAMP LAMOTRIGINE · ATC N03AX09 LAMOTRIGINE · form Tablet · route Oral · ingredients LAMOTRIGINE 25 MG · company Jamp pharma corporation · schedule Prescription
Check this DIN again · Health Canada product recordJamp Lamotrigine: Formulary list price $0.0698/unit (unit not stated in source; not the patient's cost)
Ministry pays: $0.0698 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=103127 · Verify on the e-Formulary ↗ (DIN 02542730)
Source record
DIN 02542730: Jamp Lamotrigine
Raw flags: sec3=Y
Item: 281200055; group id 432; item number 1079; lccId None; manufacturer id JPC
Source form: Tab; strength: 25mg
Recorded listing: General benefit
Source prices (unrounded): $0.0698; ministry $0.0698
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02542730
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=103127
Interchangeable products
Apo-Lamotrigine · DIN 02245208 · $0.0698
Auro-Lamotrigine · DIN 02381354 · $0.0698
Lamictal · DIN 02142082 · $0.0698
Lamotrigine · DIN 02343010 · $0.0698
Lamotrigine · DIN 02428202 · $0.0698
Mylan-Lamotrigine · DIN 02265494 · $0.0698
PMS-Lamotrigine · DIN 02246897 · $0.0698
Ratio-Lamotrigine · DIN 02243352 · $0.0698
Teva-Lamotrigine · DIN 02248232 · $0.0698
Shortage status: no shortage or discontinuation reported (checked 2026-09-13T08:10:21.292534+00:00); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02542730
Shortage record checked 2026-09-13T08:10:21.292534+00:00
Lamictal · DIN 02142082 · 25mg · tablet
General benefitMarketed · checked 2026-09-02
Write on scriptno code needed
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Savings card: innoviCares lists Lamictal (Ontario list dated 2026-09-10) — pays part of the brand-versus-generic difference after other coverage; free sign-up.
(innovicares.ca ↗)1 brand, same coverage
Lamictal · DIN 02142082
Manufacturer: GlaxoSmithKline Inc., GlaxoSmithKline Consumer Health Care; listing date 1996-10-01
Health Canada: Marketed since 2002-06-14 · brand LAMICTAL · ATC N03AX09 LAMOTRIGINE · form Tablet · route Oral · ingredients LAMOTRIGINE 25 MG · company Glaxosmithkline inc · schedule Prescription
Check this DIN again · Health Canada product recordMinistry pays: $0.0698 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=17203 · Verify on the e-Formulary ↗ (DIN 02142082)
Source record
DIN 02142082: Lamictal
Raw flags: sec3=Y
Item: 281200055; group id 432; item number 1079; lccId None; manufacturer id GSK
Source form: Tab; strength: 25mg
Recorded listing: General benefit
Source prices (unrounded): $0.5505; ministry $0.0698
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02142082
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=17203
Interchangeable products
Apo-Lamotrigine · DIN 02245208 · $0.0698
Auro-Lamotrigine · DIN 02381354 · $0.0698
Jamp Lamotrigine · DIN 02542730 · $0.0698
Lamotrigine · DIN 02343010 · $0.0698
Lamotrigine · DIN 02428202 · $0.0698
Mylan-Lamotrigine · DIN 02265494 · $0.0698
PMS-Lamotrigine · DIN 02246897 · $0.0698
Ratio-Lamotrigine · DIN 02243352 · $0.0698
Teva-Lamotrigine · DIN 02248232 · $0.0698
Shortage status: resolved shortage (ended 2018-02-15); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02142082
Shortage record checked 2026-09-13T08:10:21.292534+00:00
Lamotrigine · DIN 02343010 · 25mg · tablet
General benefitMarketed · checked 2026-09-02
Write on scriptno code needed
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Brand vs generic price
Lowest DBP recovery rule under medically necessary no-substitution claims:
6.2 Medically Necessary "No Substitution" Claims
The Side Effect Reporting Form will not have to be renewed. However, the
pharmacy must maintain a copy of the prescription that contains a direction that
there be no substitution and the required Health Canada Side Effect Reporting Form
(completed and signed by the prescriber). The prescriber must write “No
Substitution” or “No Sub” on renewal or subsequent new written prescriptions, and
indicate “No Substitution” on subsequent new oral prescriptions. The dispenser will
be reimbursed the DBP plus a mark-up and the lesser of the posted usual and
customary fee or the ODB dispensing fee minus the applicable ODB co-payment
amount. Where a completed Side Effect Reporting Form is not available at the
pharmacy during an inspection, the difference between the cost of the higher-cost
product and the lowest DBP listed for the interchangeable category will be
recovered.
(ontario.ca, Revision #17; 2026-08-03 ↗)
6.2 Medically Necessary "No Substitution" Claims
The Ministry will provide reimbursement of a higher-cost interchangeable product in
medically necessary circumstances where a patient has experienced a significant
adverse reaction with two (2) lower-cost interchangeable drug products, where
available. When a prescriber identifies a patient for which it is medically necessary
that a higher cost interchangeable product be provided, the prescriber must:
• Complete, sign and forward to the pharmacist a copy of the Health Canada
side effect reporting form for each lower-cost interchangeable drug product
trialed (Side Effect Reporting Form[s]); and
• Write “No Substitution” or “No Sub” on a written prescription or indicate “No
Substitution” to the pharmacist in the case of a verbal prescription.
The prescriber should keep a copy of the completed form in the patient’s record for
future use and reference.
In the case of a written prescription, when the pharmacist or dispensing physician
receives a prescription with the written notation “No Substitution” or “No Sub”,
reimbursement will be provided for the higher-cost interchangeable product only if
the prescription is accompanied by a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed.
This form must be completely filled out noting the details of the adverse reaction
and signed by the prescriber.
In the case of a verbal prescription, the prescriber must satisfy the operator of the
pharmacy or dispensing physician that a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed
has been completed and signed by the prescriber. A written record of this verbal
prescription and the completed Health Canada Side Effect Reporting Form must be
received by the pharmacy prior to claim submission.
Upon receipt, the pharmacist must:
• Fax, submit online or mail the completed and signed form to Health Canada’s
Canada Vigilance Program; and
• Retain his or her copy of the completed and signed Side Effect Reporting
Form.
(ontario.ca, Revision #17; 2026-08-03 ↗)1 brand, same coverage
Lamotrigine · DIN 02343010
Manufacturer: Sanis Health Inc.; listing date 2011-08-04
Health Canada: Marketed since 2010-02-16 · brand LAMOTRIGINE · ATC N03AX09 LAMOTRIGINE · form Tablet · route Oral · ingredients LAMOTRIGINE 25 MG · company Sanis health inc · schedule Prescription
Check this DIN again · Health Canada product recordLamotrigine: Formulary list price $0.0698/unit (unit not stated in source; not the patient's cost)
Ministry pays: $0.0698 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=82850 · Verify on the e-Formulary ↗ (DIN 02343010)
Source record
DIN 02343010: Lamotrigine
Raw flags: sec3=Y
Item: 281200055; group id 432; item number 1079; lccId None; manufacturer id SAI
Source form: Tab; strength: 25mg
Recorded listing: General benefit
Source prices (unrounded): $0.0698; ministry $0.0698
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02343010
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=82850
Interchangeable products
Apo-Lamotrigine · DIN 02245208 · $0.0698
Auro-Lamotrigine · DIN 02381354 · $0.0698
Jamp Lamotrigine · DIN 02542730 · $0.0698
Lamictal · DIN 02142082 · $0.0698
Lamotrigine · DIN 02428202 · $0.0698
Mylan-Lamotrigine · DIN 02265494 · $0.0698
PMS-Lamotrigine · DIN 02246897 · $0.0698
Ratio-Lamotrigine · DIN 02243352 · $0.0698
Teva-Lamotrigine · DIN 02248232 · $0.0698
Shortage status: no shortage or discontinuation reported (checked 2026-09-13T08:10:21.292534+00:00); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02343010
Shortage record checked 2026-09-13T08:10:21.292534+00:00
Lamotrigine · DIN 02428202 · 25mg · tablet
General benefitMarketed · checked 2026-09-02
Write on scriptno code needed
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Brand vs generic price
Lowest DBP recovery rule under medically necessary no-substitution claims:
6.2 Medically Necessary "No Substitution" Claims
The Side Effect Reporting Form will not have to be renewed. However, the
pharmacy must maintain a copy of the prescription that contains a direction that
there be no substitution and the required Health Canada Side Effect Reporting Form
(completed and signed by the prescriber). The prescriber must write “No
Substitution” or “No Sub” on renewal or subsequent new written prescriptions, and
indicate “No Substitution” on subsequent new oral prescriptions. The dispenser will
be reimbursed the DBP plus a mark-up and the lesser of the posted usual and
customary fee or the ODB dispensing fee minus the applicable ODB co-payment
amount. Where a completed Side Effect Reporting Form is not available at the
pharmacy during an inspection, the difference between the cost of the higher-cost
product and the lowest DBP listed for the interchangeable category will be
recovered.
(ontario.ca, Revision #17; 2026-08-03 ↗)
6.2 Medically Necessary "No Substitution" Claims
The Ministry will provide reimbursement of a higher-cost interchangeable product in
medically necessary circumstances where a patient has experienced a significant
adverse reaction with two (2) lower-cost interchangeable drug products, where
available. When a prescriber identifies a patient for which it is medically necessary
that a higher cost interchangeable product be provided, the prescriber must:
• Complete, sign and forward to the pharmacist a copy of the Health Canada
side effect reporting form for each lower-cost interchangeable drug product
trialed (Side Effect Reporting Form[s]); and
• Write “No Substitution” or “No Sub” on a written prescription or indicate “No
Substitution” to the pharmacist in the case of a verbal prescription.
The prescriber should keep a copy of the completed form in the patient’s record for
future use and reference.
In the case of a written prescription, when the pharmacist or dispensing physician
receives a prescription with the written notation “No Substitution” or “No Sub”,
reimbursement will be provided for the higher-cost interchangeable product only if
the prescription is accompanied by a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed.
This form must be completely filled out noting the details of the adverse reaction
and signed by the prescriber.
In the case of a verbal prescription, the prescriber must satisfy the operator of the
pharmacy or dispensing physician that a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed
has been completed and signed by the prescriber. A written record of this verbal
prescription and the completed Health Canada Side Effect Reporting Form must be
received by the pharmacy prior to claim submission.
Upon receipt, the pharmacist must:
• Fax, submit online or mail the completed and signed form to Health Canada’s
Canada Vigilance Program; and
• Retain his or her copy of the completed and signed Side Effect Reporting
Form.
(ontario.ca, Revision #17; 2026-08-03 ↗)1 brand, same coverage
Lamotrigine · DIN 02428202
Manufacturer: Sivem Pharmaceuticals ULC; listing date 2020-08-28
Health Canada: Marketed since 2014-10-08 · brand LAMOTRIGINE · ATC N03AX09 LAMOTRIGINE · form Tablet · route Oral · ingredients LAMOTRIGINE 25 MG · company Sivem pharmaceuticals ulc · schedule Prescription
Check this DIN again · Health Canada product recordLamotrigine: Formulary list price $0.0698/unit (unit not stated in source; not the patient's cost)
Ministry pays: $0.0698 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=91268 · Verify on the e-Formulary ↗ (DIN 02428202)
Source record
DIN 02428202: Lamotrigine
Raw flags: sec3=Y
Item: 281200055; group id 432; item number 1079; lccId None; manufacturer id SIV
Source form: Tab; strength: 25mg
Recorded listing: General benefit
Source prices (unrounded): $0.0698; ministry $0.0698
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02428202
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=91268
Interchangeable products
Apo-Lamotrigine · DIN 02245208 · $0.0698
Auro-Lamotrigine · DIN 02381354 · $0.0698
Jamp Lamotrigine · DIN 02542730 · $0.0698
Lamictal · DIN 02142082 · $0.0698
Lamotrigine · DIN 02343010 · $0.0698
Mylan-Lamotrigine · DIN 02265494 · $0.0698
PMS-Lamotrigine · DIN 02246897 · $0.0698
Ratio-Lamotrigine · DIN 02243352 · $0.0698
Teva-Lamotrigine · DIN 02248232 · $0.0698
Shortage status: no shortage or discontinuation reported (checked 2026-09-13T08:10:21.292534+00:00); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02428202
Shortage record checked 2026-09-13T08:10:21.292534+00:00
Mylan-Lamotrigine · DIN 02265494 · 25mg · tablet
General benefitMarketed · checked 2026-09-02
Write on scriptno code needed
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Brand vs generic price
Lowest DBP recovery rule under medically necessary no-substitution claims:
6.2 Medically Necessary "No Substitution" Claims
The Side Effect Reporting Form will not have to be renewed. However, the
pharmacy must maintain a copy of the prescription that contains a direction that
there be no substitution and the required Health Canada Side Effect Reporting Form
(completed and signed by the prescriber). The prescriber must write “No
Substitution” or “No Sub” on renewal or subsequent new written prescriptions, and
indicate “No Substitution” on subsequent new oral prescriptions. The dispenser will
be reimbursed the DBP plus a mark-up and the lesser of the posted usual and
customary fee or the ODB dispensing fee minus the applicable ODB co-payment
amount. Where a completed Side Effect Reporting Form is not available at the
pharmacy during an inspection, the difference between the cost of the higher-cost
product and the lowest DBP listed for the interchangeable category will be
recovered.
(ontario.ca, Revision #17; 2026-08-03 ↗)
6.2 Medically Necessary "No Substitution" Claims
The Ministry will provide reimbursement of a higher-cost interchangeable product in
medically necessary circumstances where a patient has experienced a significant
adverse reaction with two (2) lower-cost interchangeable drug products, where
available. When a prescriber identifies a patient for which it is medically necessary
that a higher cost interchangeable product be provided, the prescriber must:
• Complete, sign and forward to the pharmacist a copy of the Health Canada
side effect reporting form for each lower-cost interchangeable drug product
trialed (Side Effect Reporting Form[s]); and
• Write “No Substitution” or “No Sub” on a written prescription or indicate “No
Substitution” to the pharmacist in the case of a verbal prescription.
The prescriber should keep a copy of the completed form in the patient’s record for
future use and reference.
In the case of a written prescription, when the pharmacist or dispensing physician
receives a prescription with the written notation “No Substitution” or “No Sub”,
reimbursement will be provided for the higher-cost interchangeable product only if
the prescription is accompanied by a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed.
This form must be completely filled out noting the details of the adverse reaction
and signed by the prescriber.
In the case of a verbal prescription, the prescriber must satisfy the operator of the
pharmacy or dispensing physician that a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed
has been completed and signed by the prescriber. A written record of this verbal
prescription and the completed Health Canada Side Effect Reporting Form must be
received by the pharmacy prior to claim submission.
Upon receipt, the pharmacist must:
• Fax, submit online or mail the completed and signed form to Health Canada’s
Canada Vigilance Program; and
• Retain his or her copy of the completed and signed Side Effect Reporting
Form.
(ontario.ca, Revision #17; 2026-08-03 ↗)1 brand, same coverage
Mylan-Lamotrigine · DIN 02265494
Manufacturer: Mylan Pharmaceuticals ULC; listing date 2005-07-14
Health Canada: Marketed since 2009-10-22 · brand MYLAN-LAMOTRIGINE · ATC N03AX09 LAMOTRIGINE · form Tablet · route Oral · ingredients LAMOTRIGINE 25 MG · company Mylan pharmaceuticals ulc · schedule Prescription
Check this DIN again · Health Canada product recordMylan-Lamotrigine: Formulary list price $0.0698/unit (unit not stated in source; not the patient's cost)
Ministry pays: $0.0698 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=75095 · Verify on the e-Formulary ↗ (DIN 02265494)
Source record
DIN 02265494: Mylan-Lamotrigine
Raw flags: sec3=Y
Item: 281200055; group id 432; item number 1079; lccId None; manufacturer id MYL
Source form: Tab; strength: 25mg
Recorded listing: General benefit
Source prices (unrounded): $0.0698; ministry $0.0698
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02265494
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=75095
Interchangeable products
Apo-Lamotrigine · DIN 02245208 · $0.0698
Auro-Lamotrigine · DIN 02381354 · $0.0698
Jamp Lamotrigine · DIN 02542730 · $0.0698
Lamictal · DIN 02142082 · $0.0698
Lamotrigine · DIN 02343010 · $0.0698
Lamotrigine · DIN 02428202 · $0.0698
PMS-Lamotrigine · DIN 02246897 · $0.0698
Ratio-Lamotrigine · DIN 02243352 · $0.0698
Teva-Lamotrigine · DIN 02248232 · $0.0698
Shortage status: resolved shortage (ended 2025-08-07); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02265494
Shortage record checked 2026-09-13T08:10:21.292534+00:00
Apo-Lamotrigine · DIN 02245209 · 100mg · tablet
General benefitMarketed · checked 2026-09-02
Write on scriptno code needed
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Brand vs generic price
Lowest DBP recovery rule under medically necessary no-substitution claims:
6.2 Medically Necessary "No Substitution" Claims
The Side Effect Reporting Form will not have to be renewed. However, the
pharmacy must maintain a copy of the prescription that contains a direction that
there be no substitution and the required Health Canada Side Effect Reporting Form
(completed and signed by the prescriber). The prescriber must write “No
Substitution” or “No Sub” on renewal or subsequent new written prescriptions, and
indicate “No Substitution” on subsequent new oral prescriptions. The dispenser will
be reimbursed the DBP plus a mark-up and the lesser of the posted usual and
customary fee or the ODB dispensing fee minus the applicable ODB co-payment
amount. Where a completed Side Effect Reporting Form is not available at the
pharmacy during an inspection, the difference between the cost of the higher-cost
product and the lowest DBP listed for the interchangeable category will be
recovered.
(ontario.ca, Revision #17; 2026-08-03 ↗)
6.2 Medically Necessary "No Substitution" Claims
The Ministry will provide reimbursement of a higher-cost interchangeable product in
medically necessary circumstances where a patient has experienced a significant
adverse reaction with two (2) lower-cost interchangeable drug products, where
available. When a prescriber identifies a patient for which it is medically necessary
that a higher cost interchangeable product be provided, the prescriber must:
• Complete, sign and forward to the pharmacist a copy of the Health Canada
side effect reporting form for each lower-cost interchangeable drug product
trialed (Side Effect Reporting Form[s]); and
• Write “No Substitution” or “No Sub” on a written prescription or indicate “No
Substitution” to the pharmacist in the case of a verbal prescription.
The prescriber should keep a copy of the completed form in the patient’s record for
future use and reference.
In the case of a written prescription, when the pharmacist or dispensing physician
receives a prescription with the written notation “No Substitution” or “No Sub”,
reimbursement will be provided for the higher-cost interchangeable product only if
the prescription is accompanied by a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed.
This form must be completely filled out noting the details of the adverse reaction
and signed by the prescriber.
In the case of a verbal prescription, the prescriber must satisfy the operator of the
pharmacy or dispensing physician that a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed
has been completed and signed by the prescriber. A written record of this verbal
prescription and the completed Health Canada Side Effect Reporting Form must be
received by the pharmacy prior to claim submission.
Upon receipt, the pharmacist must:
• Fax, submit online or mail the completed and signed form to Health Canada’s
Canada Vigilance Program; and
• Retain his or her copy of the completed and signed Side Effect Reporting
Form.
(ontario.ca, Revision #17; 2026-08-03 ↗)1 brand, same coverage
Apo-Lamotrigine · DIN 02245209
Manufacturer: Apotex Inc.; listing date 2003-01-30
Health Canada: Marketed since 2017-08-04 · brand APO-LAMOTRIGINE · ATC N03AX09 LAMOTRIGINE · form Tablet · route Oral · ingredients LAMOTRIGINE 100 MG · company Apotex inc · schedule Prescription
Check this DIN again · Health Canada product recordApo-Lamotrigine: Formulary list price $0.2787/unit (unit not stated in source; not the patient's cost)
Ministry pays: $0.2787 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=69224 · Verify on the e-Formulary ↗ (DIN 02245209)
Source record
DIN 02245209: Apo-Lamotrigine
Raw flags: sec3=Y
Item: 281200059; group id 432; item number 1080; lccId None; manufacturer id APX
Source form: Tab; strength: 100mg
Recorded listing: General benefit
Source prices (unrounded): $0.2787; ministry $0.2787
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02245209
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=69224
Interchangeable products
Auro-Lamotrigine · DIN 02381362 · $0.2787
Jamp Lamotrigine · DIN 02542749 · $0.2787
Lamictal · DIN 02142104 · $0.2787
Lamotrigine · DIN 02343029 · $0.2787
Lamotrigine · DIN 02428210 · $0.2787
Mylan-Lamotrigine · DIN 02265508 · $0.2787
PMS-Lamotrigine · DIN 02246898 · $0.2787
Teva-Lamotrigine · DIN 02248233 · $0.2787
Shortage status: resolved shortage (ended 2023-09-28); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02245209
Shortage record checked 2026-09-13T08:10:21.292534+00:00
Auro-Lamotrigine · DIN 02381362 · 100mg · tablet
General benefitMarketed · checked 2026-09-02
Write on scriptno code needed
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Brand vs generic price
Lowest DBP recovery rule under medically necessary no-substitution claims:
6.2 Medically Necessary "No Substitution" Claims
The Side Effect Reporting Form will not have to be renewed. However, the
pharmacy must maintain a copy of the prescription that contains a direction that
there be no substitution and the required Health Canada Side Effect Reporting Form
(completed and signed by the prescriber). The prescriber must write “No
Substitution” or “No Sub” on renewal or subsequent new written prescriptions, and
indicate “No Substitution” on subsequent new oral prescriptions. The dispenser will
be reimbursed the DBP plus a mark-up and the lesser of the posted usual and
customary fee or the ODB dispensing fee minus the applicable ODB co-payment
amount. Where a completed Side Effect Reporting Form is not available at the
pharmacy during an inspection, the difference between the cost of the higher-cost
product and the lowest DBP listed for the interchangeable category will be
recovered.
(ontario.ca, Revision #17; 2026-08-03 ↗)
6.2 Medically Necessary "No Substitution" Claims
The Ministry will provide reimbursement of a higher-cost interchangeable product in
medically necessary circumstances where a patient has experienced a significant
adverse reaction with two (2) lower-cost interchangeable drug products, where
available. When a prescriber identifies a patient for which it is medically necessary
that a higher cost interchangeable product be provided, the prescriber must:
• Complete, sign and forward to the pharmacist a copy of the Health Canada
side effect reporting form for each lower-cost interchangeable drug product
trialed (Side Effect Reporting Form[s]); and
• Write “No Substitution” or “No Sub” on a written prescription or indicate “No
Substitution” to the pharmacist in the case of a verbal prescription.
The prescriber should keep a copy of the completed form in the patient’s record for
future use and reference.
In the case of a written prescription, when the pharmacist or dispensing physician
receives a prescription with the written notation “No Substitution” or “No Sub”,
reimbursement will be provided for the higher-cost interchangeable product only if
the prescription is accompanied by a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed.
This form must be completely filled out noting the details of the adverse reaction
and signed by the prescriber.
In the case of a verbal prescription, the prescriber must satisfy the operator of the
pharmacy or dispensing physician that a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed
has been completed and signed by the prescriber. A written record of this verbal
prescription and the completed Health Canada Side Effect Reporting Form must be
received by the pharmacy prior to claim submission.
Upon receipt, the pharmacist must:
• Fax, submit online or mail the completed and signed form to Health Canada’s
Canada Vigilance Program; and
• Retain his or her copy of the completed and signed Side Effect Reporting
Form.
(ontario.ca, Revision #17; 2026-08-03 ↗)1 brand, same coverage
Auro-Lamotrigine · DIN 02381362
Manufacturer: Auro Pharma Inc.; listing date 2012-08-27
Health Canada: Marketed since 2012-06-13 · brand AURO-LAMOTRIGINE · ATC N03AX09 LAMOTRIGINE · form Tablet · route Oral · ingredients LAMOTRIGINE 100 MG · company Auro pharma inc · schedule Prescription
Check this DIN again · Health Canada product recordAuro-Lamotrigine: Formulary list price $0.2787/unit (unit not stated in source; not the patient's cost)
Ministry pays: $0.2787 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=86719 · Verify on the e-Formulary ↗ (DIN 02381362)
Source record
DIN 02381362: Auro-Lamotrigine
Raw flags: sec3=Y
Item: 281200059; group id 432; item number 1080; lccId None; manufacturer id AUR
Source form: Tab; strength: 100mg
Recorded listing: General benefit
Source prices (unrounded): $0.2787; ministry $0.2787
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02381362
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=86719
Interchangeable products
Apo-Lamotrigine · DIN 02245209 · $0.2787
Jamp Lamotrigine · DIN 02542749 · $0.2787
Lamictal · DIN 02142104 · $0.2787
Lamotrigine · DIN 02343029 · $0.2787
Lamotrigine · DIN 02428210 · $0.2787
Mylan-Lamotrigine · DIN 02265508 · $0.2787
PMS-Lamotrigine · DIN 02246898 · $0.2787
Teva-Lamotrigine · DIN 02248233 · $0.2787
Shortage status: resolved shortage (ended 2024-10-16); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02381362
Shortage record checked 2026-09-13T08:10:21.292534+00:00
Jamp Lamotrigine · DIN 02542749 · 100mg · tablet
General benefitMarketed · checked 2026-09-02
Write on scriptno code needed
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Brand vs generic price
Lowest DBP recovery rule under medically necessary no-substitution claims:
6.2 Medically Necessary "No Substitution" Claims
The Side Effect Reporting Form will not have to be renewed. However, the
pharmacy must maintain a copy of the prescription that contains a direction that
there be no substitution and the required Health Canada Side Effect Reporting Form
(completed and signed by the prescriber). The prescriber must write “No
Substitution” or “No Sub” on renewal or subsequent new written prescriptions, and
indicate “No Substitution” on subsequent new oral prescriptions. The dispenser will
be reimbursed the DBP plus a mark-up and the lesser of the posted usual and
customary fee or the ODB dispensing fee minus the applicable ODB co-payment
amount. Where a completed Side Effect Reporting Form is not available at the
pharmacy during an inspection, the difference between the cost of the higher-cost
product and the lowest DBP listed for the interchangeable category will be
recovered.
(ontario.ca, Revision #17; 2026-08-03 ↗)
6.2 Medically Necessary "No Substitution" Claims
The Ministry will provide reimbursement of a higher-cost interchangeable product in
medically necessary circumstances where a patient has experienced a significant
adverse reaction with two (2) lower-cost interchangeable drug products, where
available. When a prescriber identifies a patient for which it is medically necessary
that a higher cost interchangeable product be provided, the prescriber must:
• Complete, sign and forward to the pharmacist a copy of the Health Canada
side effect reporting form for each lower-cost interchangeable drug product
trialed (Side Effect Reporting Form[s]); and
• Write “No Substitution” or “No Sub” on a written prescription or indicate “No
Substitution” to the pharmacist in the case of a verbal prescription.
The prescriber should keep a copy of the completed form in the patient’s record for
future use and reference.
In the case of a written prescription, when the pharmacist or dispensing physician
receives a prescription with the written notation “No Substitution” or “No Sub”,
reimbursement will be provided for the higher-cost interchangeable product only if
the prescription is accompanied by a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed.
This form must be completely filled out noting the details of the adverse reaction
and signed by the prescriber.
In the case of a verbal prescription, the prescriber must satisfy the operator of the
pharmacy or dispensing physician that a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed
has been completed and signed by the prescriber. A written record of this verbal
prescription and the completed Health Canada Side Effect Reporting Form must be
received by the pharmacy prior to claim submission.
Upon receipt, the pharmacist must:
• Fax, submit online or mail the completed and signed form to Health Canada’s
Canada Vigilance Program; and
• Retain his or her copy of the completed and signed Side Effect Reporting
Form.
(ontario.ca, Revision #17; 2026-08-03 ↗)1 brand, same coverage
Jamp Lamotrigine · DIN 02542749
Manufacturer: Jamp Pharma Corporation; listing date 2024-08-30
Health Canada: Marketed since 2024-06-21 · brand JAMP LAMOTRIGINE · ATC N03AX09 LAMOTRIGINE · form Tablet · route Oral · ingredients LAMOTRIGINE 100 MG · company Jamp pharma corporation · schedule Prescription
Check this DIN again · Health Canada product recordJamp Lamotrigine: Formulary list price $0.2787/unit (unit not stated in source; not the patient's cost)
Ministry pays: $0.2787 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=103128 · Verify on the e-Formulary ↗ (DIN 02542749)
Source record
DIN 02542749: Jamp Lamotrigine
Raw flags: sec3=Y
Item: 281200059; group id 432; item number 1080; lccId None; manufacturer id JPC
Source form: Tab; strength: 100mg
Recorded listing: General benefit
Source prices (unrounded): $0.2787; ministry $0.2787
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02542749
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=103128
Interchangeable products
Apo-Lamotrigine · DIN 02245209 · $0.2787
Auro-Lamotrigine · DIN 02381362 · $0.2787
Lamictal · DIN 02142104 · $0.2787
Lamotrigine · DIN 02343029 · $0.2787
Lamotrigine · DIN 02428210 · $0.2787
Mylan-Lamotrigine · DIN 02265508 · $0.2787
PMS-Lamotrigine · DIN 02246898 · $0.2787
Teva-Lamotrigine · DIN 02248233 · $0.2787
Shortage status: no shortage or discontinuation reported (checked 2026-09-13T08:10:21.292534+00:00); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02542749
Shortage record checked 2026-09-13T08:10:21.292534+00:00
Lamictal · DIN 02142104 · 100mg · tablet
General benefitMarketed · checked 2026-09-02
Write on scriptno code needed
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Savings card: innoviCares lists Lamictal (Ontario list dated 2026-09-10) — pays part of the brand-versus-generic difference after other coverage; free sign-up.
(innovicares.ca ↗)1 brand, same coverage
Lamictal · DIN 02142104
Manufacturer: GlaxoSmithKline Inc., GlaxoSmithKline Consumer Health Care; listing date 1996-10-01
Health Canada: Marketed since 2002-05-22 · brand LAMICTAL · ATC N03AX09 LAMOTRIGINE · form Tablet · route Oral · ingredients LAMOTRIGINE 100 MG · company Glaxosmithkline inc · schedule Prescription
Check this DIN again · Health Canada product recordMinistry pays: $0.2787 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=17201 · Verify on the e-Formulary ↗ (DIN 02142104)
Source record
DIN 02142104: Lamictal
Raw flags: sec3=Y
Item: 281200059; group id 432; item number 1080; lccId None; manufacturer id GSK
Source form: Tab; strength: 100mg
Recorded listing: General benefit
Source prices (unrounded): $2.1990; ministry $0.2787
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02142104
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=17201
Interchangeable products
Apo-Lamotrigine · DIN 02245209 · $0.2787
Auro-Lamotrigine · DIN 02381362 · $0.2787
Jamp Lamotrigine · DIN 02542749 · $0.2787
Lamotrigine · DIN 02343029 · $0.2787
Lamotrigine · DIN 02428210 · $0.2787
Mylan-Lamotrigine · DIN 02265508 · $0.2787
PMS-Lamotrigine · DIN 02246898 · $0.2787
Teva-Lamotrigine · DIN 02248233 · $0.2787
Shortage status: resolved shortage (ended 2018-05-25); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02142104
Shortage record checked 2026-09-13T08:10:21.292534+00:00
Lamotrigine · DIN 02343029 · 100mg · tablet
General benefitMarketed · checked 2026-09-02
Write on scriptno code needed
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Brand vs generic price
Lowest DBP recovery rule under medically necessary no-substitution claims:
6.2 Medically Necessary "No Substitution" Claims
The Side Effect Reporting Form will not have to be renewed. However, the
pharmacy must maintain a copy of the prescription that contains a direction that
there be no substitution and the required Health Canada Side Effect Reporting Form
(completed and signed by the prescriber). The prescriber must write “No
Substitution” or “No Sub” on renewal or subsequent new written prescriptions, and
indicate “No Substitution” on subsequent new oral prescriptions. The dispenser will
be reimbursed the DBP plus a mark-up and the lesser of the posted usual and
customary fee or the ODB dispensing fee minus the applicable ODB co-payment
amount. Where a completed Side Effect Reporting Form is not available at the
pharmacy during an inspection, the difference between the cost of the higher-cost
product and the lowest DBP listed for the interchangeable category will be
recovered.
(ontario.ca, Revision #17; 2026-08-03 ↗)
6.2 Medically Necessary "No Substitution" Claims
The Ministry will provide reimbursement of a higher-cost interchangeable product in
medically necessary circumstances where a patient has experienced a significant
adverse reaction with two (2) lower-cost interchangeable drug products, where
available. When a prescriber identifies a patient for which it is medically necessary
that a higher cost interchangeable product be provided, the prescriber must:
• Complete, sign and forward to the pharmacist a copy of the Health Canada
side effect reporting form for each lower-cost interchangeable drug product
trialed (Side Effect Reporting Form[s]); and
• Write “No Substitution” or “No Sub” on a written prescription or indicate “No
Substitution” to the pharmacist in the case of a verbal prescription.
The prescriber should keep a copy of the completed form in the patient’s record for
future use and reference.
In the case of a written prescription, when the pharmacist or dispensing physician
receives a prescription with the written notation “No Substitution” or “No Sub”,
reimbursement will be provided for the higher-cost interchangeable product only if
the prescription is accompanied by a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed.
This form must be completely filled out noting the details of the adverse reaction
and signed by the prescriber.
In the case of a verbal prescription, the prescriber must satisfy the operator of the
pharmacy or dispensing physician that a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed
has been completed and signed by the prescriber. A written record of this verbal
prescription and the completed Health Canada Side Effect Reporting Form must be
received by the pharmacy prior to claim submission.
Upon receipt, the pharmacist must:
• Fax, submit online or mail the completed and signed form to Health Canada’s
Canada Vigilance Program; and
• Retain his or her copy of the completed and signed Side Effect Reporting
Form.
(ontario.ca, Revision #17; 2026-08-03 ↗)1 brand, same coverage
Lamotrigine · DIN 02343029
Manufacturer: Sanis Health Inc.; listing date 2011-08-04
Health Canada: Marketed since 2010-02-16 · brand LAMOTRIGINE · ATC N03AX09 LAMOTRIGINE · form Tablet · route Oral · ingredients LAMOTRIGINE 100 MG · company Sanis health inc · schedule Prescription
Check this DIN again · Health Canada product recordLamotrigine: Formulary list price $0.2787/unit (unit not stated in source; not the patient's cost)
Ministry pays: $0.2787 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=82851 · Verify on the e-Formulary ↗ (DIN 02343029)
Source record
DIN 02343029: Lamotrigine
Raw flags: sec3=Y
Item: 281200059; group id 432; item number 1080; lccId None; manufacturer id SAI
Source form: Tab; strength: 100mg
Recorded listing: General benefit
Source prices (unrounded): $0.2787; ministry $0.2787
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02343029
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=82851
Interchangeable products
Apo-Lamotrigine · DIN 02245209 · $0.2787
Auro-Lamotrigine · DIN 02381362 · $0.2787
Jamp Lamotrigine · DIN 02542749 · $0.2787
Lamictal · DIN 02142104 · $0.2787
Lamotrigine · DIN 02428210 · $0.2787
Mylan-Lamotrigine · DIN 02265508 · $0.2787
PMS-Lamotrigine · DIN 02246898 · $0.2787
Teva-Lamotrigine · DIN 02248233 · $0.2787
Shortage status: resolved shortage (ended 2025-05-01); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02343029
Shortage record checked 2026-09-13T08:10:21.292534+00:00
Lamotrigine · DIN 02428210 · 100mg · tablet
General benefitMarketed · checked 2026-09-02
Write on scriptno code needed
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Brand vs generic price
Lowest DBP recovery rule under medically necessary no-substitution claims:
6.2 Medically Necessary "No Substitution" Claims
The Side Effect Reporting Form will not have to be renewed. However, the
pharmacy must maintain a copy of the prescription that contains a direction that
there be no substitution and the required Health Canada Side Effect Reporting Form
(completed and signed by the prescriber). The prescriber must write “No
Substitution” or “No Sub” on renewal or subsequent new written prescriptions, and
indicate “No Substitution” on subsequent new oral prescriptions. The dispenser will
be reimbursed the DBP plus a mark-up and the lesser of the posted usual and
customary fee or the ODB dispensing fee minus the applicable ODB co-payment
amount. Where a completed Side Effect Reporting Form is not available at the
pharmacy during an inspection, the difference between the cost of the higher-cost
product and the lowest DBP listed for the interchangeable category will be
recovered.
(ontario.ca, Revision #17; 2026-08-03 ↗)
6.2 Medically Necessary "No Substitution" Claims
The Ministry will provide reimbursement of a higher-cost interchangeable product in
medically necessary circumstances where a patient has experienced a significant
adverse reaction with two (2) lower-cost interchangeable drug products, where
available. When a prescriber identifies a patient for which it is medically necessary
that a higher cost interchangeable product be provided, the prescriber must:
• Complete, sign and forward to the pharmacist a copy of the Health Canada
side effect reporting form for each lower-cost interchangeable drug product
trialed (Side Effect Reporting Form[s]); and
• Write “No Substitution” or “No Sub” on a written prescription or indicate “No
Substitution” to the pharmacist in the case of a verbal prescription.
The prescriber should keep a copy of the completed form in the patient’s record for
future use and reference.
In the case of a written prescription, when the pharmacist or dispensing physician
receives a prescription with the written notation “No Substitution” or “No Sub”,
reimbursement will be provided for the higher-cost interchangeable product only if
the prescription is accompanied by a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed.
This form must be completely filled out noting the details of the adverse reaction
and signed by the prescriber.
In the case of a verbal prescription, the prescriber must satisfy the operator of the
pharmacy or dispensing physician that a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed
has been completed and signed by the prescriber. A written record of this verbal
prescription and the completed Health Canada Side Effect Reporting Form must be
received by the pharmacy prior to claim submission.
Upon receipt, the pharmacist must:
• Fax, submit online or mail the completed and signed form to Health Canada’s
Canada Vigilance Program; and
• Retain his or her copy of the completed and signed Side Effect Reporting
Form.
(ontario.ca, Revision #17; 2026-08-03 ↗)1 brand, same coverage
Lamotrigine · DIN 02428210
Manufacturer: Sivem Pharmaceuticals ULC; listing date 2020-08-28
Health Canada: Marketed since 2014-10-08 · brand LAMOTRIGINE · ATC N03AX09 LAMOTRIGINE · form Tablet · route Oral · ingredients LAMOTRIGINE 100 MG · company Sivem pharmaceuticals ulc · schedule Prescription
Check this DIN again · Health Canada product recordLamotrigine: Formulary list price $0.2787/unit (unit not stated in source; not the patient's cost)
Ministry pays: $0.2787 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=91269 · Verify on the e-Formulary ↗ (DIN 02428210)
Source record
DIN 02428210: Lamotrigine
Raw flags: sec3=Y
Item: 281200059; group id 432; item number 1080; lccId None; manufacturer id SIV
Source form: Tab; strength: 100mg
Recorded listing: General benefit
Source prices (unrounded): $0.2787; ministry $0.2787
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02428210
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=91269
Interchangeable products
Apo-Lamotrigine · DIN 02245209 · $0.2787
Auro-Lamotrigine · DIN 02381362 · $0.2787
Jamp Lamotrigine · DIN 02542749 · $0.2787
Lamictal · DIN 02142104 · $0.2787
Lamotrigine · DIN 02343029 · $0.2787
Mylan-Lamotrigine · DIN 02265508 · $0.2787
PMS-Lamotrigine · DIN 02246898 · $0.2787
Teva-Lamotrigine · DIN 02248233 · $0.2787
Shortage status: resolved shortage (ended 2024-12-09); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02428210
Shortage record checked 2026-09-13T08:10:21.292534+00:00
Mylan-Lamotrigine · DIN 02265508 · 100mg · tablet
General benefitMarketed · checked 2026-09-02
Write on scriptno code needed
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Brand vs generic price
Lowest DBP recovery rule under medically necessary no-substitution claims:
6.2 Medically Necessary "No Substitution" Claims
The Side Effect Reporting Form will not have to be renewed. However, the
pharmacy must maintain a copy of the prescription that contains a direction that
there be no substitution and the required Health Canada Side Effect Reporting Form
(completed and signed by the prescriber). The prescriber must write “No
Substitution” or “No Sub” on renewal or subsequent new written prescriptions, and
indicate “No Substitution” on subsequent new oral prescriptions. The dispenser will
be reimbursed the DBP plus a mark-up and the lesser of the posted usual and
customary fee or the ODB dispensing fee minus the applicable ODB co-payment
amount. Where a completed Side Effect Reporting Form is not available at the
pharmacy during an inspection, the difference between the cost of the higher-cost
product and the lowest DBP listed for the interchangeable category will be
recovered.
(ontario.ca, Revision #17; 2026-08-03 ↗)
6.2 Medically Necessary "No Substitution" Claims
The Ministry will provide reimbursement of a higher-cost interchangeable product in
medically necessary circumstances where a patient has experienced a significant
adverse reaction with two (2) lower-cost interchangeable drug products, where
available. When a prescriber identifies a patient for which it is medically necessary
that a higher cost interchangeable product be provided, the prescriber must:
• Complete, sign and forward to the pharmacist a copy of the Health Canada
side effect reporting form for each lower-cost interchangeable drug product
trialed (Side Effect Reporting Form[s]); and
• Write “No Substitution” or “No Sub” on a written prescription or indicate “No
Substitution” to the pharmacist in the case of a verbal prescription.
The prescriber should keep a copy of the completed form in the patient’s record for
future use and reference.
In the case of a written prescription, when the pharmacist or dispensing physician
receives a prescription with the written notation “No Substitution” or “No Sub”,
reimbursement will be provided for the higher-cost interchangeable product only if
the prescription is accompanied by a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed.
This form must be completely filled out noting the details of the adverse reaction
and signed by the prescriber.
In the case of a verbal prescription, the prescriber must satisfy the operator of the
pharmacy or dispensing physician that a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed
has been completed and signed by the prescriber. A written record of this verbal
prescription and the completed Health Canada Side Effect Reporting Form must be
received by the pharmacy prior to claim submission.
Upon receipt, the pharmacist must:
• Fax, submit online or mail the completed and signed form to Health Canada’s
Canada Vigilance Program; and
• Retain his or her copy of the completed and signed Side Effect Reporting
Form.
(ontario.ca, Revision #17; 2026-08-03 ↗)1 brand, same coverage
Mylan-Lamotrigine · DIN 02265508
Manufacturer: Mylan Pharmaceuticals ULC; listing date 2005-07-14
Health Canada: Marketed since 2009-10-21 · brand MYLAN-LAMOTRIGINE · ATC N03AX09 LAMOTRIGINE · form Tablet · route Oral · ingredients LAMOTRIGINE 100 MG · company Mylan pharmaceuticals ulc · schedule Prescription
Check this DIN again · Health Canada product recordMylan-Lamotrigine: Formulary list price $0.2787/unit (unit not stated in source; not the patient's cost)
Ministry pays: $0.2787 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=75096 · Verify on the e-Formulary ↗ (DIN 02265508)
Source record
DIN 02265508: Mylan-Lamotrigine
Raw flags: sec3=Y
Item: 281200059; group id 432; item number 1080; lccId None; manufacturer id MYL
Source form: Tab; strength: 100mg
Recorded listing: General benefit
Source prices (unrounded): $0.2787; ministry $0.2787
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02265508
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=75096
Interchangeable products
Apo-Lamotrigine · DIN 02245209 · $0.2787
Auro-Lamotrigine · DIN 02381362 · $0.2787
Jamp Lamotrigine · DIN 02542749 · $0.2787
Lamictal · DIN 02142104 · $0.2787
Lamotrigine · DIN 02343029 · $0.2787
Lamotrigine · DIN 02428210 · $0.2787
PMS-Lamotrigine · DIN 02246898 · $0.2787
Teva-Lamotrigine · DIN 02248233 · $0.2787
Shortage status: avoided shortage; reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02265508
Shortage record checked 2026-09-13T08:10:21.292534+00:00
Apo-Lamotrigine · DIN 02245210 · 150mg · tablet
General benefitMarketed · checked 2026-09-02
Write on scriptno code needed
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Brand vs generic price
Lowest DBP recovery rule under medically necessary no-substitution claims:
6.2 Medically Necessary "No Substitution" Claims
The Side Effect Reporting Form will not have to be renewed. However, the
pharmacy must maintain a copy of the prescription that contains a direction that
there be no substitution and the required Health Canada Side Effect Reporting Form
(completed and signed by the prescriber). The prescriber must write “No
Substitution” or “No Sub” on renewal or subsequent new written prescriptions, and
indicate “No Substitution” on subsequent new oral prescriptions. The dispenser will
be reimbursed the DBP plus a mark-up and the lesser of the posted usual and
customary fee or the ODB dispensing fee minus the applicable ODB co-payment
amount. Where a completed Side Effect Reporting Form is not available at the
pharmacy during an inspection, the difference between the cost of the higher-cost
product and the lowest DBP listed for the interchangeable category will be
recovered.
(ontario.ca, Revision #17; 2026-08-03 ↗)
6.2 Medically Necessary "No Substitution" Claims
The Ministry will provide reimbursement of a higher-cost interchangeable product in
medically necessary circumstances where a patient has experienced a significant
adverse reaction with two (2) lower-cost interchangeable drug products, where
available. When a prescriber identifies a patient for which it is medically necessary
that a higher cost interchangeable product be provided, the prescriber must:
• Complete, sign and forward to the pharmacist a copy of the Health Canada
side effect reporting form for each lower-cost interchangeable drug product
trialed (Side Effect Reporting Form[s]); and
• Write “No Substitution” or “No Sub” on a written prescription or indicate “No
Substitution” to the pharmacist in the case of a verbal prescription.
The prescriber should keep a copy of the completed form in the patient’s record for
future use and reference.
In the case of a written prescription, when the pharmacist or dispensing physician
receives a prescription with the written notation “No Substitution” or “No Sub”,
reimbursement will be provided for the higher-cost interchangeable product only if
the prescription is accompanied by a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed.
This form must be completely filled out noting the details of the adverse reaction
and signed by the prescriber.
In the case of a verbal prescription, the prescriber must satisfy the operator of the
pharmacy or dispensing physician that a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed
has been completed and signed by the prescriber. A written record of this verbal
prescription and the completed Health Canada Side Effect Reporting Form must be
received by the pharmacy prior to claim submission.
Upon receipt, the pharmacist must:
• Fax, submit online or mail the completed and signed form to Health Canada’s
Canada Vigilance Program; and
• Retain his or her copy of the completed and signed Side Effect Reporting
Form.
(ontario.ca, Revision #17; 2026-08-03 ↗)1 brand, same coverage
Apo-Lamotrigine · DIN 02245210
Manufacturer: Apotex Inc.; listing date 2003-01-30
Health Canada: Marketed since 2002-03-18 · brand APO-LAMOTRIGINE · ATC N03AX09 LAMOTRIGINE · form Tablet · route Oral · ingredients LAMOTRIGINE 150 MG · company Apotex inc · schedule Prescription
Check this DIN again · Health Canada product recordApo-Lamotrigine: Formulary list price $0.4107/unit (unit not stated in source; not the patient's cost)
Ministry pays: $0.4107 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=69225 · Verify on the e-Formulary ↗ (DIN 02245210)
Source record
DIN 02245210: Apo-Lamotrigine
Raw flags: sec3=Y
Item: 281200060; group id 432; item number 1081; lccId None; manufacturer id APX
Source form: Tab; strength: 150mg
Recorded listing: General benefit
Source prices (unrounded): $0.4107; ministry $0.4107
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02245210
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=69225
Interchangeable products
Auro-Lamotrigine · DIN 02381370 · $0.4107
Jamp Lamotrigine · DIN 02542757 · $0.4107
Lamictal · DIN 02142112 · $0.4107
Lamotrigine · DIN 02343037 · $0.4107
Lamotrigine · DIN 02428229 · $0.4107
Mylan-Lamotrigine · DIN 02265516 · $0.4107
PMS-Lamotrigine · DIN 02246899 · $0.4107
Teva-Lamotrigine · DIN 02248234 · $0.4107
Shortage status: resolved shortage (ended 2023-10-05); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02245210
Shortage record checked 2026-09-13T08:10:21.292534+00:00
Auro-Lamotrigine · DIN 02381370 · 150mg · tablet
General benefitMarketed · checked 2026-09-02
Write on scriptno code needed
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Brand vs generic price
Lowest DBP recovery rule under medically necessary no-substitution claims:
6.2 Medically Necessary "No Substitution" Claims
The Side Effect Reporting Form will not have to be renewed. However, the
pharmacy must maintain a copy of the prescription that contains a direction that
there be no substitution and the required Health Canada Side Effect Reporting Form
(completed and signed by the prescriber). The prescriber must write “No
Substitution” or “No Sub” on renewal or subsequent new written prescriptions, and
indicate “No Substitution” on subsequent new oral prescriptions. The dispenser will
be reimbursed the DBP plus a mark-up and the lesser of the posted usual and
customary fee or the ODB dispensing fee minus the applicable ODB co-payment
amount. Where a completed Side Effect Reporting Form is not available at the
pharmacy during an inspection, the difference between the cost of the higher-cost
product and the lowest DBP listed for the interchangeable category will be
recovered.
(ontario.ca, Revision #17; 2026-08-03 ↗)
6.2 Medically Necessary "No Substitution" Claims
The Ministry will provide reimbursement of a higher-cost interchangeable product in
medically necessary circumstances where a patient has experienced a significant
adverse reaction with two (2) lower-cost interchangeable drug products, where
available. When a prescriber identifies a patient for which it is medically necessary
that a higher cost interchangeable product be provided, the prescriber must:
• Complete, sign and forward to the pharmacist a copy of the Health Canada
side effect reporting form for each lower-cost interchangeable drug product
trialed (Side Effect Reporting Form[s]); and
• Write “No Substitution” or “No Sub” on a written prescription or indicate “No
Substitution” to the pharmacist in the case of a verbal prescription.
The prescriber should keep a copy of the completed form in the patient’s record for
future use and reference.
In the case of a written prescription, when the pharmacist or dispensing physician
receives a prescription with the written notation “No Substitution” or “No Sub”,
reimbursement will be provided for the higher-cost interchangeable product only if
the prescription is accompanied by a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed.
This form must be completely filled out noting the details of the adverse reaction
and signed by the prescriber.
In the case of a verbal prescription, the prescriber must satisfy the operator of the
pharmacy or dispensing physician that a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed
has been completed and signed by the prescriber. A written record of this verbal
prescription and the completed Health Canada Side Effect Reporting Form must be
received by the pharmacy prior to claim submission.
Upon receipt, the pharmacist must:
• Fax, submit online or mail the completed and signed form to Health Canada’s
Canada Vigilance Program; and
• Retain his or her copy of the completed and signed Side Effect Reporting
Form.
(ontario.ca, Revision #17; 2026-08-03 ↗)1 brand, same coverage
Auro-Lamotrigine · DIN 02381370
Manufacturer: Auro Pharma Inc.; listing date 2012-08-27
Health Canada: Marketed since 2012-06-13 · brand AURO-LAMOTRIGINE · ATC N03AX09 LAMOTRIGINE · form Tablet · route Oral · ingredients LAMOTRIGINE 150 MG · company Auro pharma inc · schedule Prescription
Check this DIN again · Health Canada product recordAuro-Lamotrigine: Formulary list price $0.4107/unit (unit not stated in source; not the patient's cost)
Ministry pays: $0.4107 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=86720 · Verify on the e-Formulary ↗ (DIN 02381370)
Source record
DIN 02381370: Auro-Lamotrigine
Raw flags: sec3=Y
Item: 281200060; group id 432; item number 1081; lccId None; manufacturer id AUR
Source form: Tab; strength: 150mg
Recorded listing: General benefit
Source prices (unrounded): $0.4107; ministry $0.4107
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02381370
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=86720
Interchangeable products
Apo-Lamotrigine · DIN 02245210 · $0.4107
Jamp Lamotrigine · DIN 02542757 · $0.4107
Lamictal · DIN 02142112 · $0.4107
Lamotrigine · DIN 02343037 · $0.4107
Lamotrigine · DIN 02428229 · $0.4107
Mylan-Lamotrigine · DIN 02265516 · $0.4107
PMS-Lamotrigine · DIN 02246899 · $0.4107
Teva-Lamotrigine · DIN 02248234 · $0.4107
Shortage status: resolved shortage (ended 2024-10-16); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02381370
Shortage record checked 2026-09-13T08:10:21.292534+00:00
Jamp Lamotrigine · DIN 02542757 · 150mg · tablet
General benefitMarketed · checked 2026-09-02
Write on scriptno code needed
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Brand vs generic price
Lowest DBP recovery rule under medically necessary no-substitution claims:
6.2 Medically Necessary "No Substitution" Claims
The Side Effect Reporting Form will not have to be renewed. However, the
pharmacy must maintain a copy of the prescription that contains a direction that
there be no substitution and the required Health Canada Side Effect Reporting Form
(completed and signed by the prescriber). The prescriber must write “No
Substitution” or “No Sub” on renewal or subsequent new written prescriptions, and
indicate “No Substitution” on subsequent new oral prescriptions. The dispenser will
be reimbursed the DBP plus a mark-up and the lesser of the posted usual and
customary fee or the ODB dispensing fee minus the applicable ODB co-payment
amount. Where a completed Side Effect Reporting Form is not available at the
pharmacy during an inspection, the difference between the cost of the higher-cost
product and the lowest DBP listed for the interchangeable category will be
recovered.
(ontario.ca, Revision #17; 2026-08-03 ↗)
6.2 Medically Necessary "No Substitution" Claims
The Ministry will provide reimbursement of a higher-cost interchangeable product in
medically necessary circumstances where a patient has experienced a significant
adverse reaction with two (2) lower-cost interchangeable drug products, where
available. When a prescriber identifies a patient for which it is medically necessary
that a higher cost interchangeable product be provided, the prescriber must:
• Complete, sign and forward to the pharmacist a copy of the Health Canada
side effect reporting form for each lower-cost interchangeable drug product
trialed (Side Effect Reporting Form[s]); and
• Write “No Substitution” or “No Sub” on a written prescription or indicate “No
Substitution” to the pharmacist in the case of a verbal prescription.
The prescriber should keep a copy of the completed form in the patient’s record for
future use and reference.
In the case of a written prescription, when the pharmacist or dispensing physician
receives a prescription with the written notation “No Substitution” or “No Sub”,
reimbursement will be provided for the higher-cost interchangeable product only if
the prescription is accompanied by a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed.
This form must be completely filled out noting the details of the adverse reaction
and signed by the prescriber.
In the case of a verbal prescription, the prescriber must satisfy the operator of the
pharmacy or dispensing physician that a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed
has been completed and signed by the prescriber. A written record of this verbal
prescription and the completed Health Canada Side Effect Reporting Form must be
received by the pharmacy prior to claim submission.
Upon receipt, the pharmacist must:
• Fax, submit online or mail the completed and signed form to Health Canada’s
Canada Vigilance Program; and
• Retain his or her copy of the completed and signed Side Effect Reporting
Form.
(ontario.ca, Revision #17; 2026-08-03 ↗)1 brand, same coverage
Jamp Lamotrigine · DIN 02542757
Manufacturer: Jamp Pharma Corporation; listing date 2024-08-30
Health Canada: Marketed since 2024-06-21 · brand JAMP LAMOTRIGINE · ATC N03AX09 LAMOTRIGINE · form Tablet · route Oral · ingredients LAMOTRIGINE 150 MG · company Jamp pharma corporation · schedule Prescription
Check this DIN again · Health Canada product recordJamp Lamotrigine: Formulary list price $0.4107/unit (unit not stated in source; not the patient's cost)
Ministry pays: $0.4107 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=103129 · Verify on the e-Formulary ↗ (DIN 02542757)
Source record
DIN 02542757: Jamp Lamotrigine
Raw flags: sec3=Y
Item: 281200060; group id 432; item number 1081; lccId None; manufacturer id JPC
Source form: Tab; strength: 150mg
Recorded listing: General benefit
Source prices (unrounded): $0.4107; ministry $0.4107
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02542757
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=103129
Interchangeable products
Apo-Lamotrigine · DIN 02245210 · $0.4107
Auro-Lamotrigine · DIN 02381370 · $0.4107
Lamictal · DIN 02142112 · $0.4107
Lamotrigine · DIN 02343037 · $0.4107
Lamotrigine · DIN 02428229 · $0.4107
Mylan-Lamotrigine · DIN 02265516 · $0.4107
PMS-Lamotrigine · DIN 02246899 · $0.4107
Teva-Lamotrigine · DIN 02248234 · $0.4107
Shortage status: no shortage or discontinuation reported (checked 2026-09-13T08:10:21.292534+00:00); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02542757
Shortage record checked 2026-09-13T08:10:21.292534+00:00
Lamictal · DIN 02142112 · 150mg · tablet
General benefitMarketed · checked 2026-09-02
Write on scriptno code needed
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Savings card: innoviCares lists Lamictal (Ontario list dated 2026-09-10) — pays part of the brand-versus-generic difference after other coverage; free sign-up.
(innovicares.ca ↗)1 brand, same coverage
Lamictal · DIN 02142112
Manufacturer: GlaxoSmithKline Inc., GlaxoSmithKline Consumer Health Care; listing date 1996-10-01
Health Canada: Marketed since 2002-03-07 · brand LAMICTAL · ATC N03AX09 LAMOTRIGINE · form Tablet · route Oral · ingredients LAMOTRIGINE 150 MG · company Glaxosmithkline inc · schedule Prescription
Check this DIN again · Health Canada product recordMinistry pays: $0.4107 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=17160 · Verify on the e-Formulary ↗ (DIN 02142112)
Source record
DIN 02142112: Lamictal
Raw flags: sec3=Y
Item: 281200060; group id 432; item number 1081; lccId None; manufacturer id GSK
Source form: Tab; strength: 150mg
Recorded listing: General benefit
Source prices (unrounded): $3.2408; ministry $0.4107
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02142112
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=17160
Interchangeable products
Apo-Lamotrigine · DIN 02245210 · $0.4107
Auro-Lamotrigine · DIN 02381370 · $0.4107
Jamp Lamotrigine · DIN 02542757 · $0.4107
Lamotrigine · DIN 02343037 · $0.4107
Lamotrigine · DIN 02428229 · $0.4107
Mylan-Lamotrigine · DIN 02265516 · $0.4107
PMS-Lamotrigine · DIN 02246899 · $0.4107
Teva-Lamotrigine · DIN 02248234 · $0.4107
Shortage status: resolved shortage (ended 2018-03-15); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02142112
Shortage record checked 2026-09-13T08:10:21.292534+00:00
Lamotrigine · DIN 02343037 · 150mg · tablet
General benefitMarketed · checked 2026-09-02
Write on scriptno code needed
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Brand vs generic price
Lowest DBP recovery rule under medically necessary no-substitution claims:
6.2 Medically Necessary "No Substitution" Claims
The Side Effect Reporting Form will not have to be renewed. However, the
pharmacy must maintain a copy of the prescription that contains a direction that
there be no substitution and the required Health Canada Side Effect Reporting Form
(completed and signed by the prescriber). The prescriber must write “No
Substitution” or “No Sub” on renewal or subsequent new written prescriptions, and
indicate “No Substitution” on subsequent new oral prescriptions. The dispenser will
be reimbursed the DBP plus a mark-up and the lesser of the posted usual and
customary fee or the ODB dispensing fee minus the applicable ODB co-payment
amount. Where a completed Side Effect Reporting Form is not available at the
pharmacy during an inspection, the difference between the cost of the higher-cost
product and the lowest DBP listed for the interchangeable category will be
recovered.
(ontario.ca, Revision #17; 2026-08-03 ↗)
6.2 Medically Necessary "No Substitution" Claims
The Ministry will provide reimbursement of a higher-cost interchangeable product in
medically necessary circumstances where a patient has experienced a significant
adverse reaction with two (2) lower-cost interchangeable drug products, where
available. When a prescriber identifies a patient for which it is medically necessary
that a higher cost interchangeable product be provided, the prescriber must:
• Complete, sign and forward to the pharmacist a copy of the Health Canada
side effect reporting form for each lower-cost interchangeable drug product
trialed (Side Effect Reporting Form[s]); and
• Write “No Substitution” or “No Sub” on a written prescription or indicate “No
Substitution” to the pharmacist in the case of a verbal prescription.
The prescriber should keep a copy of the completed form in the patient’s record for
future use and reference.
In the case of a written prescription, when the pharmacist or dispensing physician
receives a prescription with the written notation “No Substitution” or “No Sub”,
reimbursement will be provided for the higher-cost interchangeable product only if
the prescription is accompanied by a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed.
This form must be completely filled out noting the details of the adverse reaction
and signed by the prescriber.
In the case of a verbal prescription, the prescriber must satisfy the operator of the
pharmacy or dispensing physician that a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed
has been completed and signed by the prescriber. A written record of this verbal
prescription and the completed Health Canada Side Effect Reporting Form must be
received by the pharmacy prior to claim submission.
Upon receipt, the pharmacist must:
• Fax, submit online or mail the completed and signed form to Health Canada’s
Canada Vigilance Program; and
• Retain his or her copy of the completed and signed Side Effect Reporting
Form.
(ontario.ca, Revision #17; 2026-08-03 ↗)1 brand, same coverage
Lamotrigine · DIN 02343037
Manufacturer: Sanis Health Inc.; listing date 2011-08-04
Health Canada: Marketed since 2010-02-16 · brand LAMOTRIGINE · ATC N03AX09 LAMOTRIGINE · form Tablet · route Oral · ingredients LAMOTRIGINE 150 MG · company Sanis health inc · schedule Prescription
Check this DIN again · Health Canada product recordLamotrigine: Formulary list price $0.4107/unit (unit not stated in source; not the patient's cost)
Ministry pays: $0.4107 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=82852 · Verify on the e-Formulary ↗ (DIN 02343037)
Source record
DIN 02343037: Lamotrigine
Raw flags: sec3=Y
Item: 281200060; group id 432; item number 1081; lccId None; manufacturer id SAI
Source form: Tab; strength: 150mg
Recorded listing: General benefit
Source prices (unrounded): $0.4107; ministry $0.4107
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02343037
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=82852
Interchangeable products
Apo-Lamotrigine · DIN 02245210 · $0.4107
Auro-Lamotrigine · DIN 02381370 · $0.4107
Jamp Lamotrigine · DIN 02542757 · $0.4107
Lamictal · DIN 02142112 · $0.4107
Lamotrigine · DIN 02428229 · $0.4107
Mylan-Lamotrigine · DIN 02265516 · $0.4107
PMS-Lamotrigine · DIN 02246899 · $0.4107
Teva-Lamotrigine · DIN 02248234 · $0.4107
Shortage status: resolved shortage (ended 2026-03-04); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02343037
Shortage record checked 2026-09-13T08:10:21.292534+00:00
Lamotrigine · DIN 02428229 · 150mg · tablet
General benefitMarketed · checked 2026-09-02
Write on scriptno code needed
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Brand vs generic price
Lowest DBP recovery rule under medically necessary no-substitution claims:
6.2 Medically Necessary "No Substitution" Claims
The Side Effect Reporting Form will not have to be renewed. However, the
pharmacy must maintain a copy of the prescription that contains a direction that
there be no substitution and the required Health Canada Side Effect Reporting Form
(completed and signed by the prescriber). The prescriber must write “No
Substitution” or “No Sub” on renewal or subsequent new written prescriptions, and
indicate “No Substitution” on subsequent new oral prescriptions. The dispenser will
be reimbursed the DBP plus a mark-up and the lesser of the posted usual and
customary fee or the ODB dispensing fee minus the applicable ODB co-payment
amount. Where a completed Side Effect Reporting Form is not available at the
pharmacy during an inspection, the difference between the cost of the higher-cost
product and the lowest DBP listed for the interchangeable category will be
recovered.
(ontario.ca, Revision #17; 2026-08-03 ↗)
6.2 Medically Necessary "No Substitution" Claims
The Ministry will provide reimbursement of a higher-cost interchangeable product in
medically necessary circumstances where a patient has experienced a significant
adverse reaction with two (2) lower-cost interchangeable drug products, where
available. When a prescriber identifies a patient for which it is medically necessary
that a higher cost interchangeable product be provided, the prescriber must:
• Complete, sign and forward to the pharmacist a copy of the Health Canada
side effect reporting form for each lower-cost interchangeable drug product
trialed (Side Effect Reporting Form[s]); and
• Write “No Substitution” or “No Sub” on a written prescription or indicate “No
Substitution” to the pharmacist in the case of a verbal prescription.
The prescriber should keep a copy of the completed form in the patient’s record for
future use and reference.
In the case of a written prescription, when the pharmacist or dispensing physician
receives a prescription with the written notation “No Substitution” or “No Sub”,
reimbursement will be provided for the higher-cost interchangeable product only if
the prescription is accompanied by a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed.
This form must be completely filled out noting the details of the adverse reaction
and signed by the prescriber.
In the case of a verbal prescription, the prescriber must satisfy the operator of the
pharmacy or dispensing physician that a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed
has been completed and signed by the prescriber. A written record of this verbal
prescription and the completed Health Canada Side Effect Reporting Form must be
received by the pharmacy prior to claim submission.
Upon receipt, the pharmacist must:
• Fax, submit online or mail the completed and signed form to Health Canada’s
Canada Vigilance Program; and
• Retain his or her copy of the completed and signed Side Effect Reporting
Form.
(ontario.ca, Revision #17; 2026-08-03 ↗)1 brand, same coverage
Lamotrigine · DIN 02428229
Manufacturer: Sivem Pharmaceuticals ULC; listing date 2020-08-28
Health Canada: Marketed since 2014-10-08 · brand LAMOTRIGINE · ATC N03AX09 LAMOTRIGINE · form Tablet · route Oral · ingredients LAMOTRIGINE 150 MG · company Sivem pharmaceuticals ulc · schedule Prescription
Check this DIN again · Health Canada product recordLamotrigine: Formulary list price $0.4107/unit (unit not stated in source; not the patient's cost)
Ministry pays: $0.4107 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=91270 · Verify on the e-Formulary ↗ (DIN 02428229)
Source record
DIN 02428229: Lamotrigine
Raw flags: sec3=Y
Item: 281200060; group id 432; item number 1081; lccId None; manufacturer id SIV
Source form: Tab; strength: 150mg
Recorded listing: General benefit
Source prices (unrounded): $0.4107; ministry $0.4107
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02428229
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=91270
Interchangeable products
Apo-Lamotrigine · DIN 02245210 · $0.4107
Auro-Lamotrigine · DIN 02381370 · $0.4107
Jamp Lamotrigine · DIN 02542757 · $0.4107
Lamictal · DIN 02142112 · $0.4107
Lamotrigine · DIN 02343037 · $0.4107
Mylan-Lamotrigine · DIN 02265516 · $0.4107
PMS-Lamotrigine · DIN 02246899 · $0.4107
Teva-Lamotrigine · DIN 02248234 · $0.4107
Shortage status: no shortage or discontinuation reported (checked 2026-09-13T08:10:21.292534+00:00); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02428229
Shortage record checked 2026-09-13T08:10:21.292534+00:00
Mylan-Lamotrigine · DIN 02265516 · 150mg · tablet
General benefitMarketed · checked 2026-09-02
Write on scriptno code needed
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Brand vs generic price
Lowest DBP recovery rule under medically necessary no-substitution claims:
6.2 Medically Necessary "No Substitution" Claims
The Side Effect Reporting Form will not have to be renewed. However, the
pharmacy must maintain a copy of the prescription that contains a direction that
there be no substitution and the required Health Canada Side Effect Reporting Form
(completed and signed by the prescriber). The prescriber must write “No
Substitution” or “No Sub” on renewal or subsequent new written prescriptions, and
indicate “No Substitution” on subsequent new oral prescriptions. The dispenser will
be reimbursed the DBP plus a mark-up and the lesser of the posted usual and
customary fee or the ODB dispensing fee minus the applicable ODB co-payment
amount. Where a completed Side Effect Reporting Form is not available at the
pharmacy during an inspection, the difference between the cost of the higher-cost
product and the lowest DBP listed for the interchangeable category will be
recovered.
(ontario.ca, Revision #17; 2026-08-03 ↗)
6.2 Medically Necessary "No Substitution" Claims
The Ministry will provide reimbursement of a higher-cost interchangeable product in
medically necessary circumstances where a patient has experienced a significant
adverse reaction with two (2) lower-cost interchangeable drug products, where
available. When a prescriber identifies a patient for which it is medically necessary
that a higher cost interchangeable product be provided, the prescriber must:
• Complete, sign and forward to the pharmacist a copy of the Health Canada
side effect reporting form for each lower-cost interchangeable drug product
trialed (Side Effect Reporting Form[s]); and
• Write “No Substitution” or “No Sub” on a written prescription or indicate “No
Substitution” to the pharmacist in the case of a verbal prescription.
The prescriber should keep a copy of the completed form in the patient’s record for
future use and reference.
In the case of a written prescription, when the pharmacist or dispensing physician
receives a prescription with the written notation “No Substitution” or “No Sub”,
reimbursement will be provided for the higher-cost interchangeable product only if
the prescription is accompanied by a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed.
This form must be completely filled out noting the details of the adverse reaction
and signed by the prescriber.
In the case of a verbal prescription, the prescriber must satisfy the operator of the
pharmacy or dispensing physician that a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed
has been completed and signed by the prescriber. A written record of this verbal
prescription and the completed Health Canada Side Effect Reporting Form must be
received by the pharmacy prior to claim submission.
Upon receipt, the pharmacist must:
• Fax, submit online or mail the completed and signed form to Health Canada’s
Canada Vigilance Program; and
• Retain his or her copy of the completed and signed Side Effect Reporting
Form.
(ontario.ca, Revision #17; 2026-08-03 ↗)1 brand, same coverage
Mylan-Lamotrigine · DIN 02265516
Manufacturer: Mylan Pharmaceuticals ULC; listing date 2005-07-14
Health Canada: Marketed since 2009-10-26 · brand MYLAN-LAMOTRIGINE · ATC N03AX09 LAMOTRIGINE · form Tablet · route Oral · ingredients LAMOTRIGINE 150 MG · company Mylan pharmaceuticals ulc · schedule Prescription
Check this DIN again · Health Canada product recordMylan-Lamotrigine: Formulary list price $0.4107/unit (unit not stated in source; not the patient's cost)
Ministry pays: $0.4107 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=75097 · Verify on the e-Formulary ↗ (DIN 02265516)
Source record
DIN 02265516: Mylan-Lamotrigine
Raw flags: sec3=Y
Item: 281200060; group id 432; item number 1081; lccId None; manufacturer id MYL
Source form: Tab; strength: 150mg
Recorded listing: General benefit
Source prices (unrounded): $0.4107; ministry $0.4107
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02265516
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=75097
Interchangeable products
Apo-Lamotrigine · DIN 02245210 · $0.4107
Auro-Lamotrigine · DIN 02381370 · $0.4107
Jamp Lamotrigine · DIN 02542757 · $0.4107
Lamictal · DIN 02142112 · $0.4107
Lamotrigine · DIN 02343037 · $0.4107
Lamotrigine · DIN 02428229 · $0.4107
PMS-Lamotrigine · DIN 02246899 · $0.4107
Teva-Lamotrigine · DIN 02248234 · $0.4107
Shortage status: resolved shortage (ended 2026-02-24); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02265516
Shortage record checked 2026-09-13T08:10:21.292534+00:00
PMS-Lamotrigine · DIN 02246897 · 25mg · tablet
Write on scriptno code needed
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Brand vs generic price
Lowest DBP recovery rule under medically necessary no-substitution claims:
6.2 Medically Necessary "No Substitution" Claims
The Side Effect Reporting Form will not have to be renewed. However, the
pharmacy must maintain a copy of the prescription that contains a direction that
there be no substitution and the required Health Canada Side Effect Reporting Form
(completed and signed by the prescriber). The prescriber must write “No
Substitution” or “No Sub” on renewal or subsequent new written prescriptions, and
indicate “No Substitution” on subsequent new oral prescriptions. The dispenser will
be reimbursed the DBP plus a mark-up and the lesser of the posted usual and
customary fee or the ODB dispensing fee minus the applicable ODB co-payment
amount. Where a completed Side Effect Reporting Form is not available at the
pharmacy during an inspection, the difference between the cost of the higher-cost
product and the lowest DBP listed for the interchangeable category will be
recovered.
(ontario.ca, Revision #17; 2026-08-03 ↗)
6.2 Medically Necessary "No Substitution" Claims
The Ministry will provide reimbursement of a higher-cost interchangeable product in
medically necessary circumstances where a patient has experienced a significant
adverse reaction with two (2) lower-cost interchangeable drug products, where
available. When a prescriber identifies a patient for which it is medically necessary
that a higher cost interchangeable product be provided, the prescriber must:
• Complete, sign and forward to the pharmacist a copy of the Health Canada
side effect reporting form for each lower-cost interchangeable drug product
trialed (Side Effect Reporting Form[s]); and
• Write “No Substitution” or “No Sub” on a written prescription or indicate “No
Substitution” to the pharmacist in the case of a verbal prescription.
The prescriber should keep a copy of the completed form in the patient’s record for
future use and reference.
In the case of a written prescription, when the pharmacist or dispensing physician
receives a prescription with the written notation “No Substitution” or “No Sub”,
reimbursement will be provided for the higher-cost interchangeable product only if
the prescription is accompanied by a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed.
This form must be completely filled out noting the details of the adverse reaction
and signed by the prescriber.
In the case of a verbal prescription, the prescriber must satisfy the operator of the
pharmacy or dispensing physician that a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed
has been completed and signed by the prescriber. A written record of this verbal
prescription and the completed Health Canada Side Effect Reporting Form must be
received by the pharmacy prior to claim submission.
Upon receipt, the pharmacist must:
• Fax, submit online or mail the completed and signed form to Health Canada’s
Canada Vigilance Program; and
• Retain his or her copy of the completed and signed Side Effect Reporting
Form.
(ontario.ca, Revision #17; 2026-08-03 ↗)1 brand, same coverage
PMS-Lamotrigine · DIN 02246897
Manufacturer: Pharmascience Inc.; listing date 2004-04-06
Health Canada: Dormant since 2025-08-01 · brand PMS-LAMOTRIGINE · ATC N03AX09 LAMOTRIGINE · form Tablet · route Oral · ingredients LAMOTRIGINE 25 MG · company Pharmascience inc · schedule Prescription
Check this DIN again · Health Canada product recordPMS-Lamotrigine: Formulary list price $0.0698/unit (unit not stated in source; not the patient's cost)
Ministry pays: $0.0698 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=71124 · Verify on the e-Formulary ↗ (DIN 02246897)
Source record
DIN 02246897: PMS-Lamotrigine
Raw flags: sec3=Y
Item: 281200055; group id 432; item number 1079; lccId None; manufacturer id PMS
Source form: Tab; strength: 25mg
Recorded listing: General benefit
Source prices (unrounded): $0.0698; ministry $0.0698
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02246897
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=71124
Interchangeable products
Apo-Lamotrigine · DIN 02245208 · $0.0698
Auro-Lamotrigine · DIN 02381354 · $0.0698
Jamp Lamotrigine · DIN 02542730 · $0.0698
Lamictal · DIN 02142082 · $0.0698
Lamotrigine · DIN 02343010 · $0.0698
Lamotrigine · DIN 02428202 · $0.0698
Mylan-Lamotrigine · DIN 02265494 · $0.0698
Ratio-Lamotrigine · DIN 02243352 · $0.0698
Teva-Lamotrigine · DIN 02248232 · $0.0698
Shortage status: discontinued (2025-05-12, reported by PHARMASCIENCE INC); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02246897
Shortage record checked 2026-09-13T08:10:21.292534+00:00
Health Canada lists this DIN as Dormant since 2025-08-01 — choose a marketed DIN from the same-category list.
PMS-Lamotrigine · DIN 02246898 · 100mg · tablet
General benefitDormant since 2025-08-01 · checked 2026-09-02
Write on scriptno code needed
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Brand vs generic price
Lowest DBP recovery rule under medically necessary no-substitution claims:
6.2 Medically Necessary "No Substitution" Claims
The Side Effect Reporting Form will not have to be renewed. However, the
pharmacy must maintain a copy of the prescription that contains a direction that
there be no substitution and the required Health Canada Side Effect Reporting Form
(completed and signed by the prescriber). The prescriber must write “No
Substitution” or “No Sub” on renewal or subsequent new written prescriptions, and
indicate “No Substitution” on subsequent new oral prescriptions. The dispenser will
be reimbursed the DBP plus a mark-up and the lesser of the posted usual and
customary fee or the ODB dispensing fee minus the applicable ODB co-payment
amount. Where a completed Side Effect Reporting Form is not available at the
pharmacy during an inspection, the difference between the cost of the higher-cost
product and the lowest DBP listed for the interchangeable category will be
recovered.
(ontario.ca, Revision #17; 2026-08-03 ↗)
6.2 Medically Necessary "No Substitution" Claims
The Ministry will provide reimbursement of a higher-cost interchangeable product in
medically necessary circumstances where a patient has experienced a significant
adverse reaction with two (2) lower-cost interchangeable drug products, where
available. When a prescriber identifies a patient for which it is medically necessary
that a higher cost interchangeable product be provided, the prescriber must:
• Complete, sign and forward to the pharmacist a copy of the Health Canada
side effect reporting form for each lower-cost interchangeable drug product
trialed (Side Effect Reporting Form[s]); and
• Write “No Substitution” or “No Sub” on a written prescription or indicate “No
Substitution” to the pharmacist in the case of a verbal prescription.
The prescriber should keep a copy of the completed form in the patient’s record for
future use and reference.
In the case of a written prescription, when the pharmacist or dispensing physician
receives a prescription with the written notation “No Substitution” or “No Sub”,
reimbursement will be provided for the higher-cost interchangeable product only if
the prescription is accompanied by a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed.
This form must be completely filled out noting the details of the adverse reaction
and signed by the prescriber.
In the case of a verbal prescription, the prescriber must satisfy the operator of the
pharmacy or dispensing physician that a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed
has been completed and signed by the prescriber. A written record of this verbal
prescription and the completed Health Canada Side Effect Reporting Form must be
received by the pharmacy prior to claim submission.
Upon receipt, the pharmacist must:
• Fax, submit online or mail the completed and signed form to Health Canada’s
Canada Vigilance Program; and
• Retain his or her copy of the completed and signed Side Effect Reporting
Form.
(ontario.ca, Revision #17; 2026-08-03 ↗)1 brand, same coverage
PMS-Lamotrigine · DIN 02246898
Manufacturer: Pharmascience Inc.; listing date 2004-04-06
Health Canada: Dormant since 2025-08-01 · brand PMS-LAMOTRIGINE · ATC N03AX09 LAMOTRIGINE · form Tablet · route Oral · ingredients LAMOTRIGINE 100 MG · company Pharmascience inc · schedule Prescription
Check this DIN again · Health Canada product recordPMS-Lamotrigine: Formulary list price $0.2787/unit (unit not stated in source; not the patient's cost)
Ministry pays: $0.2787 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=71125 · Verify on the e-Formulary ↗ (DIN 02246898)
Source record
DIN 02246898: PMS-Lamotrigine
Raw flags: sec3=Y
Item: 281200059; group id 432; item number 1080; lccId None; manufacturer id PMS
Source form: Tab; strength: 100mg
Recorded listing: General benefit
Source prices (unrounded): $0.2787; ministry $0.2787
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02246898
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=71125
Interchangeable products
Apo-Lamotrigine · DIN 02245209 · $0.2787
Auro-Lamotrigine · DIN 02381362 · $0.2787
Jamp Lamotrigine · DIN 02542749 · $0.2787
Lamictal · DIN 02142104 · $0.2787
Lamotrigine · DIN 02343029 · $0.2787
Lamotrigine · DIN 02428210 · $0.2787
Mylan-Lamotrigine · DIN 02265508 · $0.2787
Teva-Lamotrigine · DIN 02248233 · $0.2787
Shortage status: resolved shortage (ended 2023-01-04); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02246898
Shortage record checked 2026-09-13T08:10:21.292534+00:00
Health Canada lists this DIN as Dormant since 2025-08-01 — choose a marketed DIN from the same-category list.
PMS-Lamotrigine · DIN 02246899 · 150mg · tablet
General benefitDormant since 2025-08-01 · checked 2026-09-02
Write on scriptno code needed
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Brand vs generic price
Lowest DBP recovery rule under medically necessary no-substitution claims:
6.2 Medically Necessary "No Substitution" Claims
The Side Effect Reporting Form will not have to be renewed. However, the
pharmacy must maintain a copy of the prescription that contains a direction that
there be no substitution and the required Health Canada Side Effect Reporting Form
(completed and signed by the prescriber). The prescriber must write “No
Substitution” or “No Sub” on renewal or subsequent new written prescriptions, and
indicate “No Substitution” on subsequent new oral prescriptions. The dispenser will
be reimbursed the DBP plus a mark-up and the lesser of the posted usual and
customary fee or the ODB dispensing fee minus the applicable ODB co-payment
amount. Where a completed Side Effect Reporting Form is not available at the
pharmacy during an inspection, the difference between the cost of the higher-cost
product and the lowest DBP listed for the interchangeable category will be
recovered.
(ontario.ca, Revision #17; 2026-08-03 ↗)
6.2 Medically Necessary "No Substitution" Claims
The Ministry will provide reimbursement of a higher-cost interchangeable product in
medically necessary circumstances where a patient has experienced a significant
adverse reaction with two (2) lower-cost interchangeable drug products, where
available. When a prescriber identifies a patient for which it is medically necessary
that a higher cost interchangeable product be provided, the prescriber must:
• Complete, sign and forward to the pharmacist a copy of the Health Canada
side effect reporting form for each lower-cost interchangeable drug product
trialed (Side Effect Reporting Form[s]); and
• Write “No Substitution” or “No Sub” on a written prescription or indicate “No
Substitution” to the pharmacist in the case of a verbal prescription.
The prescriber should keep a copy of the completed form in the patient’s record for
future use and reference.
In the case of a written prescription, when the pharmacist or dispensing physician
receives a prescription with the written notation “No Substitution” or “No Sub”,
reimbursement will be provided for the higher-cost interchangeable product only if
the prescription is accompanied by a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed.
This form must be completely filled out noting the details of the adverse reaction
and signed by the prescriber.
In the case of a verbal prescription, the prescriber must satisfy the operator of the
pharmacy or dispensing physician that a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed
has been completed and signed by the prescriber. A written record of this verbal
prescription and the completed Health Canada Side Effect Reporting Form must be
received by the pharmacy prior to claim submission.
Upon receipt, the pharmacist must:
• Fax, submit online or mail the completed and signed form to Health Canada’s
Canada Vigilance Program; and
• Retain his or her copy of the completed and signed Side Effect Reporting
Form.
(ontario.ca, Revision #17; 2026-08-03 ↗)1 brand, same coverage
PMS-Lamotrigine · DIN 02246899
Manufacturer: Pharmascience Inc.; listing date 2004-04-06
Health Canada: Dormant since 2025-08-01 · brand PMS-LAMOTRIGINE · ATC N03AX09 LAMOTRIGINE · form Tablet · route Oral · ingredients LAMOTRIGINE 150 MG · company Pharmascience inc · schedule Prescription
Check this DIN again · Health Canada product recordPMS-Lamotrigine: Formulary list price $0.4107/unit (unit not stated in source; not the patient's cost)
Ministry pays: $0.4107 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=71126 · Verify on the e-Formulary ↗ (DIN 02246899)
Source record
DIN 02246899: PMS-Lamotrigine
Raw flags: sec3=Y
Item: 281200060; group id 432; item number 1081; lccId None; manufacturer id PMS
Source form: Tab; strength: 150mg
Recorded listing: General benefit
Source prices (unrounded): $0.4107; ministry $0.4107
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02246899
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=71126
Interchangeable products
Apo-Lamotrigine · DIN 02245210 · $0.4107
Auro-Lamotrigine · DIN 02381370 · $0.4107
Jamp Lamotrigine · DIN 02542757 · $0.4107
Lamictal · DIN 02142112 · $0.4107
Lamotrigine · DIN 02343037 · $0.4107
Lamotrigine · DIN 02428229 · $0.4107
Mylan-Lamotrigine · DIN 02265516 · $0.4107
Teva-Lamotrigine · DIN 02248234 · $0.4107
Shortage status: discontinued (2025-05-12, reported by PHARMASCIENCE INC); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02246899
Shortage record checked 2026-09-13T08:10:21.292534+00:00
Health Canada lists this DIN as Dormant since 2025-08-01 — choose a marketed DIN from the same-category list.