20 general benefit · 2 Limited Use · 2 not a benefit
Other products in the same Health Canada class (N03AX) — coverage varies; not interchangeable
Lamotrigine (Lamictal): general benefit
Brivaracetam (Brivlera): limited Use 548
Cenobamate (Xcopri): limited Use 719
Lacosamide (Vimpat): limited Use 430
Levetiracetam (PDP-Levetiracetam): limited Use 473, Limited Use 640, 705
Perampanel (Fycompa): limited Use 430, 564
14 more in the class list below
Topamax Sprinkle · DIN 02239907 · 15mg · Sprinkle capsule
Limited Use — Reason for Use code 321 requiredMarketed · checked 2026-09-02
StatusLimited Use — Reason for Use code 321 required
Write on scriptLU code 321 (patient must meet the criteria below)
Patient paysPatient pays: program not supplied; amount cannot be determined.
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Ontario Limited Use criteria — code 321
Reason for Use code 321
In children age 16 and under, as adjunctive therapy in the treatment of seizure disorders where control by other listed anticonvulsants has been unsatisfactory.
Coverage limit:
LU Authorization Period: Indefinite
No interchangeable product listed in the Ontario extract
Topamax Sprinkle · DIN 02239907
Manufacturer: Janssen-Ortho Inc.; listing date 2000-11-30
Health Canada: Marketed since 1999-06-11 · brand TOPAMAX · ATC N03AX11 TOPIRAMATE · form Capsule · route Oral · ingredients TOPIRAMATE 15 MG · company Janssen inc · schedule Prescription
Topamax Sprinkle: Formulary list price $2.2425/unit (unit not stated in source; not the patient's cost)
Ministry pays: $2.2425 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=63399 · Verify on the e-Formulary ↗ (DIN 02239907)
Source record
DIN 02239907: Topamax Sprinkle
Raw flags: sec12=Y, sec3=Y
Item: 281200079; group id 445; item number 1113; lccId 00074; manufacturer id JNO
Source form: Sprinkle Cap; strength: 15mg
Recorded listing: Limited Use: paid only with a Reason for Use code and the criteria below
Source prices (unrounded): $2.2425; ministry $2.2425
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02239907
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=63399
Shortage status: no shortage or discontinuation reported (checked 2026-09-13T08:10:21.292534+00:00); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02239907
Shortage record checked 2026-09-13T08:10:21.292534+00:00
Topamax Sprinkle · DIN 02239908 · 25mg · Sprinkle capsule
Limited Use — Reason for Use code 321 requiredMarketed · checked 2026-09-02
StatusLimited Use — Reason for Use code 321 required
Write on scriptLU code 321 (patient must meet the criteria below)
Patient paysPatient pays: program not supplied; amount cannot be determined.
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Ontario Limited Use criteria — code 321
Reason for Use code 321
In children age 16 and under, as adjunctive therapy in the treatment of seizure disorders where control by other listed anticonvulsants has been unsatisfactory.
Coverage limit:
LU Authorization Period: Indefinite
No interchangeable product listed in the Ontario extract
Topamax Sprinkle · DIN 02239908
Manufacturer: Janssen-Ortho Inc.; listing date 2000-11-30
Health Canada: Marketed since 1999-06-11 · brand TOPAMAX · ATC N03AX11 TOPIRAMATE · form Capsule · route Oral · ingredients TOPIRAMATE 25 MG · company Janssen inc · schedule Prescription
Topamax Sprinkle: Formulary list price $2.3445/unit (unit not stated in source; not the patient's cost)
Ministry pays: $2.3445 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=63400 · Verify on the e-Formulary ↗ (DIN 02239908)
Source record
DIN 02239908: Topamax Sprinkle
Raw flags: sec12=Y, sec3=Y
Item: 281200080; group id 445; item number 1114; lccId 00074; manufacturer id JNO
Source form: Sprinkle Cap; strength: 25mg
Recorded listing: Limited Use: paid only with a Reason for Use code and the criteria below
Source prices (unrounded): $2.3445; ministry $2.3445
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02239908
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=63400
Shortage status: no shortage or discontinuation reported (checked 2026-09-13T08:10:21.292534+00:00); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02239908
Shortage record checked 2026-09-13T08:10:21.292534+00:00
Apo-Topiramate · DIN 02279614 · 25mg · tablet
General benefitMarketed · checked 2026-09-02
StatusGeneral benefit
Write on scriptno code needed
Patient paysPatient pays: program not supplied; amount cannot be determined.
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Brand vs generic price
Lowest DBP recovery rule under medically necessary no-substitution claims:
6.2 Medically Necessary "No Substitution" Claims
The Side Effect Reporting Form will not have to be renewed. However, the
pharmacy must maintain a copy of the prescription that contains a direction that
there be no substitution and the required Health Canada Side Effect Reporting Form
(completed and signed by the prescriber). The prescriber must write “No
Substitution” or “No Sub” on renewal or subsequent new written prescriptions, and
indicate “No Substitution” on subsequent new oral prescriptions. The dispenser will
be reimbursed the DBP plus a mark-up and the lesser of the posted usual and
customary fee or the ODB dispensing fee minus the applicable ODB co-payment
amount. Where a completed Side Effect Reporting Form is not available at the
pharmacy during an inspection, the difference between the cost of the higher-cost
product and the lowest DBP listed for the interchangeable category will be
recovered.
(ontario.ca, Revision #17; 2026-08-03 ↗)
6.2 Medically Necessary "No Substitution" Claims
The Ministry will provide reimbursement of a higher-cost interchangeable product in
medically necessary circumstances where a patient has experienced a significant
adverse reaction with two (2) lower-cost interchangeable drug products, where
available. When a prescriber identifies a patient for which it is medically necessary
that a higher cost interchangeable product be provided, the prescriber must:
• Complete, sign and forward to the pharmacist a copy of the Health Canada
side effect reporting form for each lower-cost interchangeable drug product
trialed (Side Effect Reporting Form[s]); and
• Write “No Substitution” or “No Sub” on a written prescription or indicate “No
Substitution” to the pharmacist in the case of a verbal prescription.
The prescriber should keep a copy of the completed form in the patient’s record for
future use and reference.
In the case of a written prescription, when the pharmacist or dispensing physician
receives a prescription with the written notation “No Substitution” or “No Sub”,
reimbursement will be provided for the higher-cost interchangeable product only if
the prescription is accompanied by a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed.
This form must be completely filled out noting the details of the adverse reaction
and signed by the prescriber.
In the case of a verbal prescription, the prescriber must satisfy the operator of the
pharmacy or dispensing physician that a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed
has been completed and signed by the prescriber. A written record of this verbal
prescription and the completed Health Canada Side Effect Reporting Form must be
received by the pharmacy prior to claim submission.
Upon receipt, the pharmacist must:
• Fax, submit online or mail the completed and signed form to Health Canada’s
Canada Vigilance Program; and
• Retain his or her copy of the completed and signed Side Effect Reporting
Form.
(ontario.ca, Revision #17; 2026-08-03 ↗)
1 brand, same coverage
Apo-Topiramate · DIN 02279614
Manufacturer: Apotex Inc.; listing date 2006-06-14
Health Canada: Marketed since 2006-04-21 · brand APO-TOPIRAMATE · ATC N03AX11 TOPIRAMATE · form Tablet · route Oral · ingredients TOPIRAMATE 25 MG · company Apotex inc · schedule Prescription
Apo-Topiramate: Formulary list price $0.2433/unit (unit not stated in source; not the patient's cost)
Ministry pays: $0.2433 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=76522 · Verify on the e-Formulary ↗ (DIN 02279614)
Source record
DIN 02279614: Apo-Topiramate
Raw flags: sec3=Y
Item: 281200069; group id 446; item number 1116; lccId None; manufacturer id APX
Source form: Tab; strength: 25mg
Recorded listing: General benefit
Source prices (unrounded): $0.2433; ministry $0.2433
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02279614
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=76522Interchangeable products
AG-Topiramate · DIN 02475936 · $0.2433
Ach-Topiramate · DIN 02395738 · $0.2433
Auro-Topiramate · DIN 02345803 · $0.2433
Jamp Topiramate Tablets · DIN 02345250 · $0.2433
Jamp-Topiramate · DIN 02435608 · $0.2433
Mar-Topiramate · DIN 02432099 · $0.2433
Mint-Topiramate · DIN 02315645 · $0.2433
Mylan-Topiramate · DIN 02263351 · $0.2433
NRA-Topiramate · DIN 02538466 · $0.2433
PMS-Topiramate · DIN 02262991 · $0.2433
Sandoz Topiramate Tablets · DIN 02431807 · $0.2433
Teva-Topiramate · DIN 02248860 · $0.2433
Topamax · DIN 02230893 · $0.2433
Topiramate · DIN 02356856 · $0.2433
Topiramate · DIN 02389460 · $0.2433
Shortage status: resolved shortage (ended 2026-03-19); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02279614
Shortage record checked 2026-09-13T08:10:21.292534+00:00
Auro-Topiramate · DIN 02345803 · 25mg · tablet
General benefitMarketed · checked 2026-09-02
StatusGeneral benefit
Write on scriptno code needed
Patient paysPatient pays: program not supplied; amount cannot be determined.
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Brand vs generic price
Lowest DBP recovery rule under medically necessary no-substitution claims:
6.2 Medically Necessary "No Substitution" Claims
The Side Effect Reporting Form will not have to be renewed. However, the
pharmacy must maintain a copy of the prescription that contains a direction that
there be no substitution and the required Health Canada Side Effect Reporting Form
(completed and signed by the prescriber). The prescriber must write “No
Substitution” or “No Sub” on renewal or subsequent new written prescriptions, and
indicate “No Substitution” on subsequent new oral prescriptions. The dispenser will
be reimbursed the DBP plus a mark-up and the lesser of the posted usual and
customary fee or the ODB dispensing fee minus the applicable ODB co-payment
amount. Where a completed Side Effect Reporting Form is not available at the
pharmacy during an inspection, the difference between the cost of the higher-cost
product and the lowest DBP listed for the interchangeable category will be
recovered.
(ontario.ca, Revision #17; 2026-08-03 ↗)
6.2 Medically Necessary "No Substitution" Claims
The Ministry will provide reimbursement of a higher-cost interchangeable product in
medically necessary circumstances where a patient has experienced a significant
adverse reaction with two (2) lower-cost interchangeable drug products, where
available. When a prescriber identifies a patient for which it is medically necessary
that a higher cost interchangeable product be provided, the prescriber must:
• Complete, sign and forward to the pharmacist a copy of the Health Canada
side effect reporting form for each lower-cost interchangeable drug product
trialed (Side Effect Reporting Form[s]); and
• Write “No Substitution” or “No Sub” on a written prescription or indicate “No
Substitution” to the pharmacist in the case of a verbal prescription.
The prescriber should keep a copy of the completed form in the patient’s record for
future use and reference.
In the case of a written prescription, when the pharmacist or dispensing physician
receives a prescription with the written notation “No Substitution” or “No Sub”,
reimbursement will be provided for the higher-cost interchangeable product only if
the prescription is accompanied by a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed.
This form must be completely filled out noting the details of the adverse reaction
and signed by the prescriber.
In the case of a verbal prescription, the prescriber must satisfy the operator of the
pharmacy or dispensing physician that a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed
has been completed and signed by the prescriber. A written record of this verbal
prescription and the completed Health Canada Side Effect Reporting Form must be
received by the pharmacy prior to claim submission.
Upon receipt, the pharmacist must:
• Fax, submit online or mail the completed and signed form to Health Canada’s
Canada Vigilance Program; and
• Retain his or her copy of the completed and signed Side Effect Reporting
Form.
(ontario.ca, Revision #17; 2026-08-03 ↗)
1 brand, same coverage
Auro-Topiramate · DIN 02345803
Manufacturer: Auro Pharma Inc.; listing date 2011-09-15
Health Canada: Marketed since 2020-03-31 · brand AURO-TOPIRAMATE · ATC N03AX11 TOPIRAMATE · form Tablet · route Oral · ingredients TOPIRAMATE 25 MG · company Auro pharma inc · schedule Prescription
Auro-Topiramate: Formulary list price $0.2433/unit (unit not stated in source; not the patient's cost)
Ministry pays: $0.2433 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=83123 · Verify on the e-Formulary ↗ (DIN 02345803)
Source record
DIN 02345803: Auro-Topiramate
Raw flags: sec3=Y
Item: 281200069; group id 446; item number 1116; lccId None; manufacturer id AUR
Source form: Tab; strength: 25mg
Recorded listing: General benefit
Source prices (unrounded): $0.2433; ministry $0.2433
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02345803
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=83123Interchangeable products
AG-Topiramate · DIN 02475936 · $0.2433
Ach-Topiramate · DIN 02395738 · $0.2433
Apo-Topiramate · DIN 02279614 · $0.2433
Jamp Topiramate Tablets · DIN 02345250 · $0.2433
Jamp-Topiramate · DIN 02435608 · $0.2433
Mar-Topiramate · DIN 02432099 · $0.2433
Mint-Topiramate · DIN 02315645 · $0.2433
Mylan-Topiramate · DIN 02263351 · $0.2433
NRA-Topiramate · DIN 02538466 · $0.2433
PMS-Topiramate · DIN 02262991 · $0.2433
Sandoz Topiramate Tablets · DIN 02431807 · $0.2433
Teva-Topiramate · DIN 02248860 · $0.2433
Topamax · DIN 02230893 · $0.2433
Topiramate · DIN 02356856 · $0.2433
Topiramate · DIN 02389460 · $0.2433
Shortage status: resolved shortage (ended 2024-10-28); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02345803
Shortage record checked 2026-09-13T08:10:21.292534+00:00
Jamp Topiramate Tablets · DIN 02345250 · 25mg · tablet
General benefitMarketed · checked 2026-09-02
StatusGeneral benefit
Write on scriptno code needed
Patient paysPatient pays: program not supplied; amount cannot be determined.
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Brand vs generic price
Lowest DBP recovery rule under medically necessary no-substitution claims:
6.2 Medically Necessary "No Substitution" Claims
The Side Effect Reporting Form will not have to be renewed. However, the
pharmacy must maintain a copy of the prescription that contains a direction that
there be no substitution and the required Health Canada Side Effect Reporting Form
(completed and signed by the prescriber). The prescriber must write “No
Substitution” or “No Sub” on renewal or subsequent new written prescriptions, and
indicate “No Substitution” on subsequent new oral prescriptions. The dispenser will
be reimbursed the DBP plus a mark-up and the lesser of the posted usual and
customary fee or the ODB dispensing fee minus the applicable ODB co-payment
amount. Where a completed Side Effect Reporting Form is not available at the
pharmacy during an inspection, the difference between the cost of the higher-cost
product and the lowest DBP listed for the interchangeable category will be
recovered.
(ontario.ca, Revision #17; 2026-08-03 ↗)
6.2 Medically Necessary "No Substitution" Claims
The Ministry will provide reimbursement of a higher-cost interchangeable product in
medically necessary circumstances where a patient has experienced a significant
adverse reaction with two (2) lower-cost interchangeable drug products, where
available. When a prescriber identifies a patient for which it is medically necessary
that a higher cost interchangeable product be provided, the prescriber must:
• Complete, sign and forward to the pharmacist a copy of the Health Canada
side effect reporting form for each lower-cost interchangeable drug product
trialed (Side Effect Reporting Form[s]); and
• Write “No Substitution” or “No Sub” on a written prescription or indicate “No
Substitution” to the pharmacist in the case of a verbal prescription.
The prescriber should keep a copy of the completed form in the patient’s record for
future use and reference.
In the case of a written prescription, when the pharmacist or dispensing physician
receives a prescription with the written notation “No Substitution” or “No Sub”,
reimbursement will be provided for the higher-cost interchangeable product only if
the prescription is accompanied by a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed.
This form must be completely filled out noting the details of the adverse reaction
and signed by the prescriber.
In the case of a verbal prescription, the prescriber must satisfy the operator of the
pharmacy or dispensing physician that a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed
has been completed and signed by the prescriber. A written record of this verbal
prescription and the completed Health Canada Side Effect Reporting Form must be
received by the pharmacy prior to claim submission.
Upon receipt, the pharmacist must:
• Fax, submit online or mail the completed and signed form to Health Canada’s
Canada Vigilance Program; and
• Retain his or her copy of the completed and signed Side Effect Reporting
Form.
(ontario.ca, Revision #17; 2026-08-03 ↗)
1 brand, same coverage
Jamp Topiramate Tablets · DIN 02345250
Manufacturer: Jamp Pharma Corporation; listing date 2023-06-30
Health Canada: Marketed since 2023-03-01 · brand JAMP TOPIRAMATE TABLETS · ATC N03AX11 TOPIRAMATE · form Tablet · route Oral · ingredients TOPIRAMATE 25 MG · company Jamp pharma corporation · schedule Prescription
Jamp Topiramate Tablets: Formulary list price $0.2433/unit (unit not stated in source; not the patient's cost)
Ministry pays: $0.2433 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=83068 · Verify on the e-Formulary ↗ (DIN 02345250)
Source record
DIN 02345250: Jamp Topiramate Tablets
Raw flags: sec3=Y
Item: 281200069; group id 446; item number 1116; lccId None; manufacturer id JPC
Source form: Tab; strength: 25mg
Recorded listing: General benefit
Source prices (unrounded): $0.2433; ministry $0.2433
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02345250
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=83068Interchangeable products
AG-Topiramate · DIN 02475936 · $0.2433
Ach-Topiramate · DIN 02395738 · $0.2433
Apo-Topiramate · DIN 02279614 · $0.2433
Auro-Topiramate · DIN 02345803 · $0.2433
Jamp-Topiramate · DIN 02435608 · $0.2433
Mar-Topiramate · DIN 02432099 · $0.2433
Mint-Topiramate · DIN 02315645 · $0.2433
Mylan-Topiramate · DIN 02263351 · $0.2433
NRA-Topiramate · DIN 02538466 · $0.2433
PMS-Topiramate · DIN 02262991 · $0.2433
Sandoz Topiramate Tablets · DIN 02431807 · $0.2433
Teva-Topiramate · DIN 02248860 · $0.2433
Topamax · DIN 02230893 · $0.2433
Topiramate · DIN 02356856 · $0.2433
Topiramate · DIN 02389460 · $0.2433
Shortage status: no shortage or discontinuation reported (checked 2026-09-13T08:10:21.292534+00:00); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02345250
Shortage record checked 2026-09-13T08:10:21.292534+00:00
Mint-Topiramate · DIN 02315645 · 25mg · tablet
General benefitMarketed · checked 2026-09-02
StatusGeneral benefit
Write on scriptno code needed
Patient paysPatient pays: program not supplied; amount cannot be determined.
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Brand vs generic price
Lowest DBP recovery rule under medically necessary no-substitution claims:
6.2 Medically Necessary "No Substitution" Claims
The Side Effect Reporting Form will not have to be renewed. However, the
pharmacy must maintain a copy of the prescription that contains a direction that
there be no substitution and the required Health Canada Side Effect Reporting Form
(completed and signed by the prescriber). The prescriber must write “No
Substitution” or “No Sub” on renewal or subsequent new written prescriptions, and
indicate “No Substitution” on subsequent new oral prescriptions. The dispenser will
be reimbursed the DBP plus a mark-up and the lesser of the posted usual and
customary fee or the ODB dispensing fee minus the applicable ODB co-payment
amount. Where a completed Side Effect Reporting Form is not available at the
pharmacy during an inspection, the difference between the cost of the higher-cost
product and the lowest DBP listed for the interchangeable category will be
recovered.
(ontario.ca, Revision #17; 2026-08-03 ↗)
6.2 Medically Necessary "No Substitution" Claims
The Ministry will provide reimbursement of a higher-cost interchangeable product in
medically necessary circumstances where a patient has experienced a significant
adverse reaction with two (2) lower-cost interchangeable drug products, where
available. When a prescriber identifies a patient for which it is medically necessary
that a higher cost interchangeable product be provided, the prescriber must:
• Complete, sign and forward to the pharmacist a copy of the Health Canada
side effect reporting form for each lower-cost interchangeable drug product
trialed (Side Effect Reporting Form[s]); and
• Write “No Substitution” or “No Sub” on a written prescription or indicate “No
Substitution” to the pharmacist in the case of a verbal prescription.
The prescriber should keep a copy of the completed form in the patient’s record for
future use and reference.
In the case of a written prescription, when the pharmacist or dispensing physician
receives a prescription with the written notation “No Substitution” or “No Sub”,
reimbursement will be provided for the higher-cost interchangeable product only if
the prescription is accompanied by a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed.
This form must be completely filled out noting the details of the adverse reaction
and signed by the prescriber.
In the case of a verbal prescription, the prescriber must satisfy the operator of the
pharmacy or dispensing physician that a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed
has been completed and signed by the prescriber. A written record of this verbal
prescription and the completed Health Canada Side Effect Reporting Form must be
received by the pharmacy prior to claim submission.
Upon receipt, the pharmacist must:
• Fax, submit online or mail the completed and signed form to Health Canada’s
Canada Vigilance Program; and
• Retain his or her copy of the completed and signed Side Effect Reporting
Form.
(ontario.ca, Revision #17; 2026-08-03 ↗)
1 brand, same coverage
Mint-Topiramate · DIN 02315645
Manufacturer: Mint Pharmaceuticals Inc.; listing date 2009-03-02
Health Canada: Marketed since 2024-06-26 · brand MINT-TOPIRAMATE · ATC N03AX11 TOPIRAMATE · form Tablet · route Oral · ingredients TOPIRAMATE 25 MG · company Mint pharmaceuticals inc · schedule Prescription
Mint-Topiramate: Formulary list price $0.2433/unit (unit not stated in source; not the patient's cost)
Ministry pays: $0.2433 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=80117 · Verify on the e-Formulary ↗ (DIN 02315645)
Source record
DIN 02315645: Mint-Topiramate
Raw flags: sec3=Y
Item: 281200069; group id 446; item number 1116; lccId None; manufacturer id MIN
Source form: Tab; strength: 25mg
Recorded listing: General benefit
Source prices (unrounded): $0.2433; ministry $0.2433
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02315645
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=80117Interchangeable products
AG-Topiramate · DIN 02475936 · $0.2433
Ach-Topiramate · DIN 02395738 · $0.2433
Apo-Topiramate · DIN 02279614 · $0.2433
Auro-Topiramate · DIN 02345803 · $0.2433
Jamp Topiramate Tablets · DIN 02345250 · $0.2433
Jamp-Topiramate · DIN 02435608 · $0.2433
Mar-Topiramate · DIN 02432099 · $0.2433
Mylan-Topiramate · DIN 02263351 · $0.2433
NRA-Topiramate · DIN 02538466 · $0.2433
PMS-Topiramate · DIN 02262991 · $0.2433
Sandoz Topiramate Tablets · DIN 02431807 · $0.2433
Teva-Topiramate · DIN 02248860 · $0.2433
Topamax · DIN 02230893 · $0.2433
Topiramate · DIN 02356856 · $0.2433
Topiramate · DIN 02389460 · $0.2433
Shortage status: resolved shortage (ended 2024-03-25); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02315645
Shortage record checked 2026-09-13T08:10:21.292534+00:00
Mylan-Topiramate · DIN 02263351 · 25mg · tablet
General benefitMarketed · checked 2026-09-02
StatusGeneral benefit
Write on scriptno code needed
Patient paysPatient pays: program not supplied; amount cannot be determined.
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Brand vs generic price
Lowest DBP recovery rule under medically necessary no-substitution claims:
6.2 Medically Necessary "No Substitution" Claims
The Side Effect Reporting Form will not have to be renewed. However, the
pharmacy must maintain a copy of the prescription that contains a direction that
there be no substitution and the required Health Canada Side Effect Reporting Form
(completed and signed by the prescriber). The prescriber must write “No
Substitution” or “No Sub” on renewal or subsequent new written prescriptions, and
indicate “No Substitution” on subsequent new oral prescriptions. The dispenser will
be reimbursed the DBP plus a mark-up and the lesser of the posted usual and
customary fee or the ODB dispensing fee minus the applicable ODB co-payment
amount. Where a completed Side Effect Reporting Form is not available at the
pharmacy during an inspection, the difference between the cost of the higher-cost
product and the lowest DBP listed for the interchangeable category will be
recovered.
(ontario.ca, Revision #17; 2026-08-03 ↗)
6.2 Medically Necessary "No Substitution" Claims
The Ministry will provide reimbursement of a higher-cost interchangeable product in
medically necessary circumstances where a patient has experienced a significant
adverse reaction with two (2) lower-cost interchangeable drug products, where
available. When a prescriber identifies a patient for which it is medically necessary
that a higher cost interchangeable product be provided, the prescriber must:
• Complete, sign and forward to the pharmacist a copy of the Health Canada
side effect reporting form for each lower-cost interchangeable drug product
trialed (Side Effect Reporting Form[s]); and
• Write “No Substitution” or “No Sub” on a written prescription or indicate “No
Substitution” to the pharmacist in the case of a verbal prescription.
The prescriber should keep a copy of the completed form in the patient’s record for
future use and reference.
In the case of a written prescription, when the pharmacist or dispensing physician
receives a prescription with the written notation “No Substitution” or “No Sub”,
reimbursement will be provided for the higher-cost interchangeable product only if
the prescription is accompanied by a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed.
This form must be completely filled out noting the details of the adverse reaction
and signed by the prescriber.
In the case of a verbal prescription, the prescriber must satisfy the operator of the
pharmacy or dispensing physician that a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed
has been completed and signed by the prescriber. A written record of this verbal
prescription and the completed Health Canada Side Effect Reporting Form must be
received by the pharmacy prior to claim submission.
Upon receipt, the pharmacist must:
• Fax, submit online or mail the completed and signed form to Health Canada’s
Canada Vigilance Program; and
• Retain his or her copy of the completed and signed Side Effect Reporting
Form.
(ontario.ca, Revision #17; 2026-08-03 ↗)
1 brand, same coverage
Mylan-Topiramate · DIN 02263351
Manufacturer: Mylan Pharmaceuticals ULC; listing date 2005-11-08
Health Canada: Marketed since 2009-10-21 · brand MYLAN-TOPIRAMATE · ATC N03AX11 TOPIRAMATE · form Tablet · route Oral · ingredients TOPIRAMATE 25 MG · company Mylan pharmaceuticals ulc · schedule Prescription
Mylan-Topiramate: Formulary list price $0.2433/unit (unit not stated in source; not the patient's cost)
Ministry pays: $0.2433 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=74874 · Verify on the e-Formulary ↗ (DIN 02263351)
Source record
DIN 02263351: Mylan-Topiramate
Raw flags: sec3=Y
Item: 281200069; group id 446; item number 1116; lccId None; manufacturer id MYL
Source form: Tab; strength: 25mg
Recorded listing: General benefit
Source prices (unrounded): $0.2433; ministry $0.2433
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02263351
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=74874Interchangeable products
AG-Topiramate · DIN 02475936 · $0.2433
Ach-Topiramate · DIN 02395738 · $0.2433
Apo-Topiramate · DIN 02279614 · $0.2433
Auro-Topiramate · DIN 02345803 · $0.2433
Jamp Topiramate Tablets · DIN 02345250 · $0.2433
Jamp-Topiramate · DIN 02435608 · $0.2433
Mar-Topiramate · DIN 02432099 · $0.2433
Mint-Topiramate · DIN 02315645 · $0.2433
NRA-Topiramate · DIN 02538466 · $0.2433
PMS-Topiramate · DIN 02262991 · $0.2433
Sandoz Topiramate Tablets · DIN 02431807 · $0.2433
Teva-Topiramate · DIN 02248860 · $0.2433
Topamax · DIN 02230893 · $0.2433
Topiramate · DIN 02356856 · $0.2433
Topiramate · DIN 02389460 · $0.2433
Shortage status: no shortage or discontinuation reported (checked 2026-09-13T08:10:21.292534+00:00); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02263351
Shortage record checked 2026-09-13T08:10:21.292534+00:00
NRA-Topiramate · DIN 02538466 · 25mg · tablet
General benefitMarketed · checked 2026-09-02
StatusGeneral benefit
Write on scriptno code needed
Patient paysPatient pays: program not supplied; amount cannot be determined.
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Brand vs generic price
Lowest DBP recovery rule under medically necessary no-substitution claims:
6.2 Medically Necessary "No Substitution" Claims
The Side Effect Reporting Form will not have to be renewed. However, the
pharmacy must maintain a copy of the prescription that contains a direction that
there be no substitution and the required Health Canada Side Effect Reporting Form
(completed and signed by the prescriber). The prescriber must write “No
Substitution” or “No Sub” on renewal or subsequent new written prescriptions, and
indicate “No Substitution” on subsequent new oral prescriptions. The dispenser will
be reimbursed the DBP plus a mark-up and the lesser of the posted usual and
customary fee or the ODB dispensing fee minus the applicable ODB co-payment
amount. Where a completed Side Effect Reporting Form is not available at the
pharmacy during an inspection, the difference between the cost of the higher-cost
product and the lowest DBP listed for the interchangeable category will be
recovered.
(ontario.ca, Revision #17; 2026-08-03 ↗)
6.2 Medically Necessary "No Substitution" Claims
The Ministry will provide reimbursement of a higher-cost interchangeable product in
medically necessary circumstances where a patient has experienced a significant
adverse reaction with two (2) lower-cost interchangeable drug products, where
available. When a prescriber identifies a patient for which it is medically necessary
that a higher cost interchangeable product be provided, the prescriber must:
• Complete, sign and forward to the pharmacist a copy of the Health Canada
side effect reporting form for each lower-cost interchangeable drug product
trialed (Side Effect Reporting Form[s]); and
• Write “No Substitution” or “No Sub” on a written prescription or indicate “No
Substitution” to the pharmacist in the case of a verbal prescription.
The prescriber should keep a copy of the completed form in the patient’s record for
future use and reference.
In the case of a written prescription, when the pharmacist or dispensing physician
receives a prescription with the written notation “No Substitution” or “No Sub”,
reimbursement will be provided for the higher-cost interchangeable product only if
the prescription is accompanied by a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed.
This form must be completely filled out noting the details of the adverse reaction
and signed by the prescriber.
In the case of a verbal prescription, the prescriber must satisfy the operator of the
pharmacy or dispensing physician that a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed
has been completed and signed by the prescriber. A written record of this verbal
prescription and the completed Health Canada Side Effect Reporting Form must be
received by the pharmacy prior to claim submission.
Upon receipt, the pharmacist must:
• Fax, submit online or mail the completed and signed form to Health Canada’s
Canada Vigilance Program; and
• Retain his or her copy of the completed and signed Side Effect Reporting
Form.
(ontario.ca, Revision #17; 2026-08-03 ↗)
1 brand, same coverage
NRA-Topiramate · DIN 02538466
Manufacturer: Nora Pharma; listing date 2024-04-30
Health Canada: Marketed since 2024-01-11 · brand NRA-TOPIRAMATE · ATC N03AX11 TOPIRAMATE · form Tablet · route Oral · ingredients TOPIRAMATE 25 MG · company Nora pharma inc · schedule Prescription
NRA-Topiramate: Formulary list price $0.2433/unit (unit not stated in source; not the patient's cost)
Ministry pays: $0.2433 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=102718 · Verify on the e-Formulary ↗ (DIN 02538466)
Source record
DIN 02538466: NRA-Topiramate
Raw flags: sec3=Y
Item: 281200069; group id 446; item number 1116; lccId None; manufacturer id NRA
Source form: Tab; strength: 25mg
Recorded listing: General benefit
Source prices (unrounded): $0.2433; ministry $0.2433
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02538466
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=102718Interchangeable products
AG-Topiramate · DIN 02475936 · $0.2433
Ach-Topiramate · DIN 02395738 · $0.2433
Apo-Topiramate · DIN 02279614 · $0.2433
Auro-Topiramate · DIN 02345803 · $0.2433
Jamp Topiramate Tablets · DIN 02345250 · $0.2433
Jamp-Topiramate · DIN 02435608 · $0.2433
Mar-Topiramate · DIN 02432099 · $0.2433
Mint-Topiramate · DIN 02315645 · $0.2433
Mylan-Topiramate · DIN 02263351 · $0.2433
PMS-Topiramate · DIN 02262991 · $0.2433
Sandoz Topiramate Tablets · DIN 02431807 · $0.2433
Teva-Topiramate · DIN 02248860 · $0.2433
Topamax · DIN 02230893 · $0.2433
Topiramate · DIN 02356856 · $0.2433
Topiramate · DIN 02389460 · $0.2433
Shortage status: no shortage or discontinuation reported (checked 2026-09-13T08:10:21.292534+00:00); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02538466
Shortage record checked 2026-09-13T08:10:21.292534+00:00
PMS-Topiramate · DIN 02262991 · 25mg · tablet
General benefitMarketed · checked 2026-09-02
StatusGeneral benefit
Write on scriptno code needed
Patient paysPatient pays: program not supplied; amount cannot be determined.
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Brand vs generic price
Lowest DBP recovery rule under medically necessary no-substitution claims:
6.2 Medically Necessary "No Substitution" Claims
The Side Effect Reporting Form will not have to be renewed. However, the
pharmacy must maintain a copy of the prescription that contains a direction that
there be no substitution and the required Health Canada Side Effect Reporting Form
(completed and signed by the prescriber). The prescriber must write “No
Substitution” or “No Sub” on renewal or subsequent new written prescriptions, and
indicate “No Substitution” on subsequent new oral prescriptions. The dispenser will
be reimbursed the DBP plus a mark-up and the lesser of the posted usual and
customary fee or the ODB dispensing fee minus the applicable ODB co-payment
amount. Where a completed Side Effect Reporting Form is not available at the
pharmacy during an inspection, the difference between the cost of the higher-cost
product and the lowest DBP listed for the interchangeable category will be
recovered.
(ontario.ca, Revision #17; 2026-08-03 ↗)
6.2 Medically Necessary "No Substitution" Claims
The Ministry will provide reimbursement of a higher-cost interchangeable product in
medically necessary circumstances where a patient has experienced a significant
adverse reaction with two (2) lower-cost interchangeable drug products, where
available. When a prescriber identifies a patient for which it is medically necessary
that a higher cost interchangeable product be provided, the prescriber must:
• Complete, sign and forward to the pharmacist a copy of the Health Canada
side effect reporting form for each lower-cost interchangeable drug product
trialed (Side Effect Reporting Form[s]); and
• Write “No Substitution” or “No Sub” on a written prescription or indicate “No
Substitution” to the pharmacist in the case of a verbal prescription.
The prescriber should keep a copy of the completed form in the patient’s record for
future use and reference.
In the case of a written prescription, when the pharmacist or dispensing physician
receives a prescription with the written notation “No Substitution” or “No Sub”,
reimbursement will be provided for the higher-cost interchangeable product only if
the prescription is accompanied by a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed.
This form must be completely filled out noting the details of the adverse reaction
and signed by the prescriber.
In the case of a verbal prescription, the prescriber must satisfy the operator of the
pharmacy or dispensing physician that a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed
has been completed and signed by the prescriber. A written record of this verbal
prescription and the completed Health Canada Side Effect Reporting Form must be
received by the pharmacy prior to claim submission.
Upon receipt, the pharmacist must:
• Fax, submit online or mail the completed and signed form to Health Canada’s
Canada Vigilance Program; and
• Retain his or her copy of the completed and signed Side Effect Reporting
Form.
(ontario.ca, Revision #17; 2026-08-03 ↗)
1 brand, same coverage
PMS-Topiramate · DIN 02262991
Manufacturer: Pharmascience Inc.; listing date 2005-11-08
Health Canada: Marketed since 2005-09-14 · brand PMS-TOPIRAMATE · ATC N03AX11 TOPIRAMATE · form Tablet · route Oral · ingredients TOPIRAMATE 25 MG · company Pharmascience inc · schedule Prescription
PMS-Topiramate: Formulary list price $0.2433/unit (unit not stated in source; not the patient's cost)
Ministry pays: $0.2433 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=74840 · Verify on the e-Formulary ↗ (DIN 02262991)
Source record
DIN 02262991: PMS-Topiramate
Raw flags: sec3=Y
Item: 281200069; group id 446; item number 1116; lccId None; manufacturer id PMS
Source form: Tab; strength: 25mg
Recorded listing: General benefit
Source prices (unrounded): $0.2433; ministry $0.2433
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02262991
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=74840Interchangeable products
AG-Topiramate · DIN 02475936 · $0.2433
Ach-Topiramate · DIN 02395738 · $0.2433
Apo-Topiramate · DIN 02279614 · $0.2433
Auro-Topiramate · DIN 02345803 · $0.2433
Jamp Topiramate Tablets · DIN 02345250 · $0.2433
Jamp-Topiramate · DIN 02435608 · $0.2433
Mar-Topiramate · DIN 02432099 · $0.2433
Mint-Topiramate · DIN 02315645 · $0.2433
Mylan-Topiramate · DIN 02263351 · $0.2433
NRA-Topiramate · DIN 02538466 · $0.2433
Sandoz Topiramate Tablets · DIN 02431807 · $0.2433
Teva-Topiramate · DIN 02248860 · $0.2433
Topamax · DIN 02230893 · $0.2433
Topiramate · DIN 02356856 · $0.2433
Topiramate · DIN 02389460 · $0.2433
Shortage status: resolved shortage (ended 2018-05-04); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02262991
Shortage record checked 2026-09-13T08:10:21.292534+00:00
Teva-Topiramate · DIN 02248860 · 25mg · tablet
General benefitMarketed · checked 2026-09-02
StatusGeneral benefit
Write on scriptno code needed
Patient paysPatient pays: program not supplied; amount cannot be determined.
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Brand vs generic price
Lowest DBP recovery rule under medically necessary no-substitution claims:
6.2 Medically Necessary "No Substitution" Claims
The Side Effect Reporting Form will not have to be renewed. However, the
pharmacy must maintain a copy of the prescription that contains a direction that
there be no substitution and the required Health Canada Side Effect Reporting Form
(completed and signed by the prescriber). The prescriber must write “No
Substitution” or “No Sub” on renewal or subsequent new written prescriptions, and
indicate “No Substitution” on subsequent new oral prescriptions. The dispenser will
be reimbursed the DBP plus a mark-up and the lesser of the posted usual and
customary fee or the ODB dispensing fee minus the applicable ODB co-payment
amount. Where a completed Side Effect Reporting Form is not available at the
pharmacy during an inspection, the difference between the cost of the higher-cost
product and the lowest DBP listed for the interchangeable category will be
recovered.
(ontario.ca, Revision #17; 2026-08-03 ↗)
6.2 Medically Necessary "No Substitution" Claims
The Ministry will provide reimbursement of a higher-cost interchangeable product in
medically necessary circumstances where a patient has experienced a significant
adverse reaction with two (2) lower-cost interchangeable drug products, where
available. When a prescriber identifies a patient for which it is medically necessary
that a higher cost interchangeable product be provided, the prescriber must:
• Complete, sign and forward to the pharmacist a copy of the Health Canada
side effect reporting form for each lower-cost interchangeable drug product
trialed (Side Effect Reporting Form[s]); and
• Write “No Substitution” or “No Sub” on a written prescription or indicate “No
Substitution” to the pharmacist in the case of a verbal prescription.
The prescriber should keep a copy of the completed form in the patient’s record for
future use and reference.
In the case of a written prescription, when the pharmacist or dispensing physician
receives a prescription with the written notation “No Substitution” or “No Sub”,
reimbursement will be provided for the higher-cost interchangeable product only if
the prescription is accompanied by a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed.
This form must be completely filled out noting the details of the adverse reaction
and signed by the prescriber.
In the case of a verbal prescription, the prescriber must satisfy the operator of the
pharmacy or dispensing physician that a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed
has been completed and signed by the prescriber. A written record of this verbal
prescription and the completed Health Canada Side Effect Reporting Form must be
received by the pharmacy prior to claim submission.
Upon receipt, the pharmacist must:
• Fax, submit online or mail the completed and signed form to Health Canada’s
Canada Vigilance Program; and
• Retain his or her copy of the completed and signed Side Effect Reporting
Form.
(ontario.ca, Revision #17; 2026-08-03 ↗)
1 brand, same coverage
Teva-Topiramate · DIN 02248860
Manufacturer: Teva Canada Limited; listing date 2005-11-08
Health Canada: Marketed since 2011-05-07 · brand TEVA-TOPIRAMATE · ATC N03AX11 TOPIRAMATE · form Tablet · route Oral · ingredients TOPIRAMATE 25 MG · company Teva canada limited · schedule Prescription
Teva-Topiramate: Formulary list price $0.2433/unit (unit not stated in source; not the patient's cost)
Ministry pays: $0.2433 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=73232 · Verify on the e-Formulary ↗ (DIN 02248860)
Source record
DIN 02248860: Teva-Topiramate
Raw flags: sec3=Y
Item: 281200069; group id 446; item number 1116; lccId None; manufacturer id TEV
Source form: Tab; strength: 25mg
Recorded listing: General benefit
Source prices (unrounded): $0.2433; ministry $0.2433
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02248860
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=73232Interchangeable products
AG-Topiramate · DIN 02475936 · $0.2433
Ach-Topiramate · DIN 02395738 · $0.2433
Apo-Topiramate · DIN 02279614 · $0.2433
Auro-Topiramate · DIN 02345803 · $0.2433
Jamp Topiramate Tablets · DIN 02345250 · $0.2433
Jamp-Topiramate · DIN 02435608 · $0.2433
Mar-Topiramate · DIN 02432099 · $0.2433
Mint-Topiramate · DIN 02315645 · $0.2433
Mylan-Topiramate · DIN 02263351 · $0.2433
NRA-Topiramate · DIN 02538466 · $0.2433
PMS-Topiramate · DIN 02262991 · $0.2433
Sandoz Topiramate Tablets · DIN 02431807 · $0.2433
Topamax · DIN 02230893 · $0.2433
Topiramate · DIN 02356856 · $0.2433
Topiramate · DIN 02389460 · $0.2433
Shortage status: resolved shortage (ended 2024-05-22); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02248860
Shortage record checked 2026-09-13T08:10:21.292534+00:00
Topiramate · DIN 02356856 · 25mg · tablet
General benefitMarketed · checked 2026-09-02
StatusGeneral benefit
Write on scriptno code needed
Patient paysPatient pays: program not supplied; amount cannot be determined.
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Brand vs generic price
Lowest DBP recovery rule under medically necessary no-substitution claims:
6.2 Medically Necessary "No Substitution" Claims
The Side Effect Reporting Form will not have to be renewed. However, the
pharmacy must maintain a copy of the prescription that contains a direction that
there be no substitution and the required Health Canada Side Effect Reporting Form
(completed and signed by the prescriber). The prescriber must write “No
Substitution” or “No Sub” on renewal or subsequent new written prescriptions, and
indicate “No Substitution” on subsequent new oral prescriptions. The dispenser will
be reimbursed the DBP plus a mark-up and the lesser of the posted usual and
customary fee or the ODB dispensing fee minus the applicable ODB co-payment
amount. Where a completed Side Effect Reporting Form is not available at the
pharmacy during an inspection, the difference between the cost of the higher-cost
product and the lowest DBP listed for the interchangeable category will be
recovered.
(ontario.ca, Revision #17; 2026-08-03 ↗)
6.2 Medically Necessary "No Substitution" Claims
The Ministry will provide reimbursement of a higher-cost interchangeable product in
medically necessary circumstances where a patient has experienced a significant
adverse reaction with two (2) lower-cost interchangeable drug products, where
available. When a prescriber identifies a patient for which it is medically necessary
that a higher cost interchangeable product be provided, the prescriber must:
• Complete, sign and forward to the pharmacist a copy of the Health Canada
side effect reporting form for each lower-cost interchangeable drug product
trialed (Side Effect Reporting Form[s]); and
• Write “No Substitution” or “No Sub” on a written prescription or indicate “No
Substitution” to the pharmacist in the case of a verbal prescription.
The prescriber should keep a copy of the completed form in the patient’s record for
future use and reference.
In the case of a written prescription, when the pharmacist or dispensing physician
receives a prescription with the written notation “No Substitution” or “No Sub”,
reimbursement will be provided for the higher-cost interchangeable product only if
the prescription is accompanied by a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed.
This form must be completely filled out noting the details of the adverse reaction
and signed by the prescriber.
In the case of a verbal prescription, the prescriber must satisfy the operator of the
pharmacy or dispensing physician that a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed
has been completed and signed by the prescriber. A written record of this verbal
prescription and the completed Health Canada Side Effect Reporting Form must be
received by the pharmacy prior to claim submission.
Upon receipt, the pharmacist must:
• Fax, submit online or mail the completed and signed form to Health Canada’s
Canada Vigilance Program; and
• Retain his or her copy of the completed and signed Side Effect Reporting
Form.
(ontario.ca, Revision #17; 2026-08-03 ↗)
1 brand, same coverage
Topiramate · DIN 02356856
Manufacturer: Sanis Health Inc.; listing date 2011-08-04
Health Canada: Marketed since 2010-10-06 · brand TOPIRAMATE · ATC N03AX11 TOPIRAMATE · form Tablet · route Oral · ingredients TOPIRAMATE 25 MG · company Sanis health inc · schedule Prescription
Topiramate: Formulary list price $0.2433/unit (unit not stated in source; not the patient's cost)
Ministry pays: $0.2433 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=84197 · Verify on the e-Formulary ↗ (DIN 02356856)
Source record
DIN 02356856: Topiramate
Raw flags: sec3=Y
Item: 281200069; group id 446; item number 1116; lccId None; manufacturer id SAI
Source form: Tab; strength: 25mg
Recorded listing: General benefit
Source prices (unrounded): $0.2433; ministry $0.2433
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02356856
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=84197Interchangeable products
AG-Topiramate · DIN 02475936 · $0.2433
Ach-Topiramate · DIN 02395738 · $0.2433
Apo-Topiramate · DIN 02279614 · $0.2433
Auro-Topiramate · DIN 02345803 · $0.2433
Jamp Topiramate Tablets · DIN 02345250 · $0.2433
Jamp-Topiramate · DIN 02435608 · $0.2433
Mar-Topiramate · DIN 02432099 · $0.2433
Mint-Topiramate · DIN 02315645 · $0.2433
Mylan-Topiramate · DIN 02263351 · $0.2433
NRA-Topiramate · DIN 02538466 · $0.2433
PMS-Topiramate · DIN 02262991 · $0.2433
Sandoz Topiramate Tablets · DIN 02431807 · $0.2433
Teva-Topiramate · DIN 02248860 · $0.2433
Topamax · DIN 02230893 · $0.2433
Topiramate · DIN 02389460 · $0.2433
Shortage status: anticipated shortage (last updated 2026-07-13); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02356856
Shortage record checked 2026-09-13T08:10:21.292534+00:00
Topiramate · DIN 02389460 · 25mg · tablet
General benefitMarketed · checked 2026-09-02
StatusGeneral benefit
Write on scriptno code needed
Patient paysPatient pays: program not supplied; amount cannot be determined.
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Brand vs generic price
Lowest DBP recovery rule under medically necessary no-substitution claims:
6.2 Medically Necessary "No Substitution" Claims
The Side Effect Reporting Form will not have to be renewed. However, the
pharmacy must maintain a copy of the prescription that contains a direction that
there be no substitution and the required Health Canada Side Effect Reporting Form
(completed and signed by the prescriber). The prescriber must write “No
Substitution” or “No Sub” on renewal or subsequent new written prescriptions, and
indicate “No Substitution” on subsequent new oral prescriptions. The dispenser will
be reimbursed the DBP plus a mark-up and the lesser of the posted usual and
customary fee or the ODB dispensing fee minus the applicable ODB co-payment
amount. Where a completed Side Effect Reporting Form is not available at the
pharmacy during an inspection, the difference between the cost of the higher-cost
product and the lowest DBP listed for the interchangeable category will be
recovered.
(ontario.ca, Revision #17; 2026-08-03 ↗)
6.2 Medically Necessary "No Substitution" Claims
The Ministry will provide reimbursement of a higher-cost interchangeable product in
medically necessary circumstances where a patient has experienced a significant
adverse reaction with two (2) lower-cost interchangeable drug products, where
available. When a prescriber identifies a patient for which it is medically necessary
that a higher cost interchangeable product be provided, the prescriber must:
• Complete, sign and forward to the pharmacist a copy of the Health Canada
side effect reporting form for each lower-cost interchangeable drug product
trialed (Side Effect Reporting Form[s]); and
• Write “No Substitution” or “No Sub” on a written prescription or indicate “No
Substitution” to the pharmacist in the case of a verbal prescription.
The prescriber should keep a copy of the completed form in the patient’s record for
future use and reference.
In the case of a written prescription, when the pharmacist or dispensing physician
receives a prescription with the written notation “No Substitution” or “No Sub”,
reimbursement will be provided for the higher-cost interchangeable product only if
the prescription is accompanied by a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed.
This form must be completely filled out noting the details of the adverse reaction
and signed by the prescriber.
In the case of a verbal prescription, the prescriber must satisfy the operator of the
pharmacy or dispensing physician that a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed
has been completed and signed by the prescriber. A written record of this verbal
prescription and the completed Health Canada Side Effect Reporting Form must be
received by the pharmacy prior to claim submission.
Upon receipt, the pharmacist must:
• Fax, submit online or mail the completed and signed form to Health Canada’s
Canada Vigilance Program; and
• Retain his or her copy of the completed and signed Side Effect Reporting
Form.
(ontario.ca, Revision #17; 2026-08-03 ↗)
1 brand, same coverage
Topiramate · DIN 02389460
Manufacturer: Sivem Pharmaceuticals ULC; listing date 2020-08-28
Health Canada: Marketed since 2018-07-06 · brand TOPIRAMATE · ATC N03AX11 TOPIRAMATE · form Tablet · route Oral · ingredients TOPIRAMATE 25 MG · company Sivem pharmaceuticals ulc · schedule Prescription
Topiramate: Formulary list price $0.2433/unit (unit not stated in source; not the patient's cost)
Ministry pays: $0.2433 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=87497 · Verify on the e-Formulary ↗ (DIN 02389460)
Source record
DIN 02389460: Topiramate
Raw flags: sec3=Y
Item: 281200069; group id 446; item number 1116; lccId None; manufacturer id SIV
Source form: Tab; strength: 25mg
Recorded listing: General benefit
Source prices (unrounded): $0.2433; ministry $0.2433
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02389460
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=87497Interchangeable products
AG-Topiramate · DIN 02475936 · $0.2433
Ach-Topiramate · DIN 02395738 · $0.2433
Apo-Topiramate · DIN 02279614 · $0.2433
Auro-Topiramate · DIN 02345803 · $0.2433
Jamp Topiramate Tablets · DIN 02345250 · $0.2433
Jamp-Topiramate · DIN 02435608 · $0.2433
Mar-Topiramate · DIN 02432099 · $0.2433
Mint-Topiramate · DIN 02315645 · $0.2433
Mylan-Topiramate · DIN 02263351 · $0.2433
NRA-Topiramate · DIN 02538466 · $0.2433
PMS-Topiramate · DIN 02262991 · $0.2433
Sandoz Topiramate Tablets · DIN 02431807 · $0.2433
Teva-Topiramate · DIN 02248860 · $0.2433
Topamax · DIN 02230893 · $0.2433
Topiramate · DIN 02356856 · $0.2433
Shortage status: resolved shortage (ended 2017-10-01); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02389460
Shortage record checked 2026-09-13T08:10:21.292534+00:00
Apo-Topiramate · DIN 02279630 · 100mg · tablet
General benefitMarketed · checked 2026-09-02
StatusGeneral benefit
Write on scriptno code needed
Patient paysPatient pays: program not supplied; amount cannot be determined.
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Brand vs generic price
Lowest DBP recovery rule under medically necessary no-substitution claims:
6.2 Medically Necessary "No Substitution" Claims
The Side Effect Reporting Form will not have to be renewed. However, the
pharmacy must maintain a copy of the prescription that contains a direction that
there be no substitution and the required Health Canada Side Effect Reporting Form
(completed and signed by the prescriber). The prescriber must write “No
Substitution” or “No Sub” on renewal or subsequent new written prescriptions, and
indicate “No Substitution” on subsequent new oral prescriptions. The dispenser will
be reimbursed the DBP plus a mark-up and the lesser of the posted usual and
customary fee or the ODB dispensing fee minus the applicable ODB co-payment
amount. Where a completed Side Effect Reporting Form is not available at the
pharmacy during an inspection, the difference between the cost of the higher-cost
product and the lowest DBP listed for the interchangeable category will be
recovered.
(ontario.ca, Revision #17; 2026-08-03 ↗)
6.2 Medically Necessary "No Substitution" Claims
The Ministry will provide reimbursement of a higher-cost interchangeable product in
medically necessary circumstances where a patient has experienced a significant
adverse reaction with two (2) lower-cost interchangeable drug products, where
available. When a prescriber identifies a patient for which it is medically necessary
that a higher cost interchangeable product be provided, the prescriber must:
• Complete, sign and forward to the pharmacist a copy of the Health Canada
side effect reporting form for each lower-cost interchangeable drug product
trialed (Side Effect Reporting Form[s]); and
• Write “No Substitution” or “No Sub” on a written prescription or indicate “No
Substitution” to the pharmacist in the case of a verbal prescription.
The prescriber should keep a copy of the completed form in the patient’s record for
future use and reference.
In the case of a written prescription, when the pharmacist or dispensing physician
receives a prescription with the written notation “No Substitution” or “No Sub”,
reimbursement will be provided for the higher-cost interchangeable product only if
the prescription is accompanied by a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed.
This form must be completely filled out noting the details of the adverse reaction
and signed by the prescriber.
In the case of a verbal prescription, the prescriber must satisfy the operator of the
pharmacy or dispensing physician that a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed
has been completed and signed by the prescriber. A written record of this verbal
prescription and the completed Health Canada Side Effect Reporting Form must be
received by the pharmacy prior to claim submission.
Upon receipt, the pharmacist must:
• Fax, submit online or mail the completed and signed form to Health Canada’s
Canada Vigilance Program; and
• Retain his or her copy of the completed and signed Side Effect Reporting
Form.
(ontario.ca, Revision #17; 2026-08-03 ↗)
1 brand, same coverage
Apo-Topiramate · DIN 02279630
Manufacturer: Apotex Inc.; listing date 2006-06-14
Health Canada: Marketed since 2006-04-21 · brand APO-TOPIRAMATE · ATC N03AX11 TOPIRAMATE · form Tablet · route Oral · ingredients TOPIRAMATE 100 MG · company Apotex inc · schedule Prescription
Apo-Topiramate: Formulary list price $0.4583/unit (unit not stated in source; not the patient's cost)
Ministry pays: $0.4583 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=76524 · Verify on the e-Formulary ↗ (DIN 02279630)
Source record
DIN 02279630: Apo-Topiramate
Raw flags: sec3=Y
Item: 281200070; group id 446; item number 1117; lccId None; manufacturer id APX
Source form: Tab; strength: 100mg
Recorded listing: General benefit
Source prices (unrounded): $0.4583; ministry $0.4583
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02279630
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=76524Interchangeable products
AG-Topiramate · DIN 02475944 · $0.4583
Ach-Topiramate · DIN 02395746 · $0.4583
Auro-Topiramate · DIN 02345838 · $0.4583
Jamp Topiramate Tablets · DIN 02345269 · $0.4583
Jamp-Topiramate · DIN 02435616 · $0.4583
Mar-Topiramate · DIN 02432102 · $0.4583
Mint-Topiramate · DIN 02315653 · $0.4583
Mylan-Topiramate · DIN 02263378 · $0.4583
NRA-Topiramate · DIN 02538458 · $0.4583
PMS-Topiramate · DIN 02263009 · $0.4583
Ran-Topiramate · DIN 02396084 · $0.4583
Sandoz Topiramate Tablets · DIN 02431815 · $0.4583
Teva-Topiramate · DIN 02248861 · $0.4583
Topamax · DIN 02230894 · $0.4583
Topiramate · DIN 02356864 · $0.4583
Topiramate · DIN 02389487 · $0.4583
Shortage status: resolved shortage (ended 2025-12-04); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02279630
Shortage record checked 2026-09-13T08:10:21.292534+00:00
Auro-Topiramate · DIN 02345838 · 100mg · tablet
General benefitMarketed · checked 2026-09-02
StatusGeneral benefit
Write on scriptno code needed
Patient paysPatient pays: program not supplied; amount cannot be determined.
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Brand vs generic price
Lowest DBP recovery rule under medically necessary no-substitution claims:
6.2 Medically Necessary "No Substitution" Claims
The Side Effect Reporting Form will not have to be renewed. However, the
pharmacy must maintain a copy of the prescription that contains a direction that
there be no substitution and the required Health Canada Side Effect Reporting Form
(completed and signed by the prescriber). The prescriber must write “No
Substitution” or “No Sub” on renewal or subsequent new written prescriptions, and
indicate “No Substitution” on subsequent new oral prescriptions. The dispenser will
be reimbursed the DBP plus a mark-up and the lesser of the posted usual and
customary fee or the ODB dispensing fee minus the applicable ODB co-payment
amount. Where a completed Side Effect Reporting Form is not available at the
pharmacy during an inspection, the difference between the cost of the higher-cost
product and the lowest DBP listed for the interchangeable category will be
recovered.
(ontario.ca, Revision #17; 2026-08-03 ↗)
6.2 Medically Necessary "No Substitution" Claims
The Ministry will provide reimbursement of a higher-cost interchangeable product in
medically necessary circumstances where a patient has experienced a significant
adverse reaction with two (2) lower-cost interchangeable drug products, where
available. When a prescriber identifies a patient for which it is medically necessary
that a higher cost interchangeable product be provided, the prescriber must:
• Complete, sign and forward to the pharmacist a copy of the Health Canada
side effect reporting form for each lower-cost interchangeable drug product
trialed (Side Effect Reporting Form[s]); and
• Write “No Substitution” or “No Sub” on a written prescription or indicate “No
Substitution” to the pharmacist in the case of a verbal prescription.
The prescriber should keep a copy of the completed form in the patient’s record for
future use and reference.
In the case of a written prescription, when the pharmacist or dispensing physician
receives a prescription with the written notation “No Substitution” or “No Sub”,
reimbursement will be provided for the higher-cost interchangeable product only if
the prescription is accompanied by a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed.
This form must be completely filled out noting the details of the adverse reaction
and signed by the prescriber.
In the case of a verbal prescription, the prescriber must satisfy the operator of the
pharmacy or dispensing physician that a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed
has been completed and signed by the prescriber. A written record of this verbal
prescription and the completed Health Canada Side Effect Reporting Form must be
received by the pharmacy prior to claim submission.
Upon receipt, the pharmacist must:
• Fax, submit online or mail the completed and signed form to Health Canada’s
Canada Vigilance Program; and
• Retain his or her copy of the completed and signed Side Effect Reporting
Form.
(ontario.ca, Revision #17; 2026-08-03 ↗)
1 brand, same coverage
Auro-Topiramate · DIN 02345838
Manufacturer: Auro Pharma Inc.; listing date 2011-09-15
Health Canada: Marketed since 2020-03-31 · brand AURO-TOPIRAMATE · ATC N03AX11 TOPIRAMATE · form Tablet · route Oral · ingredients TOPIRAMATE 100 MG · company Auro pharma inc · schedule Prescription
Auro-Topiramate: Formulary list price $0.4583/unit (unit not stated in source; not the patient's cost)
Ministry pays: $0.4583 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=83125 · Verify on the e-Formulary ↗ (DIN 02345838)
Source record
DIN 02345838: Auro-Topiramate
Raw flags: sec3=Y
Item: 281200070; group id 446; item number 1117; lccId None; manufacturer id AUR
Source form: Tab; strength: 100mg
Recorded listing: General benefit
Source prices (unrounded): $0.4583; ministry $0.4583
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02345838
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=83125Interchangeable products
AG-Topiramate · DIN 02475944 · $0.4583
Ach-Topiramate · DIN 02395746 · $0.4583
Apo-Topiramate · DIN 02279630 · $0.4583
Jamp Topiramate Tablets · DIN 02345269 · $0.4583
Jamp-Topiramate · DIN 02435616 · $0.4583
Mar-Topiramate · DIN 02432102 · $0.4583
Mint-Topiramate · DIN 02315653 · $0.4583
Mylan-Topiramate · DIN 02263378 · $0.4583
NRA-Topiramate · DIN 02538458 · $0.4583
PMS-Topiramate · DIN 02263009 · $0.4583
Ran-Topiramate · DIN 02396084 · $0.4583
Sandoz Topiramate Tablets · DIN 02431815 · $0.4583
Teva-Topiramate · DIN 02248861 · $0.4583
Topamax · DIN 02230894 · $0.4583
Topiramate · DIN 02356864 · $0.4583
Topiramate · DIN 02389487 · $0.4583
Shortage status: resolved shortage (ended 2025-02-06); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02345838
Shortage record checked 2026-09-13T08:10:21.292534+00:00
Jamp Topiramate Tablets · DIN 02345269 · 100mg · tablet
General benefitMarketed · checked 2026-09-02
StatusGeneral benefit
Write on scriptno code needed
Patient paysPatient pays: program not supplied; amount cannot be determined.
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Brand vs generic price
Lowest DBP recovery rule under medically necessary no-substitution claims:
6.2 Medically Necessary "No Substitution" Claims
The Side Effect Reporting Form will not have to be renewed. However, the
pharmacy must maintain a copy of the prescription that contains a direction that
there be no substitution and the required Health Canada Side Effect Reporting Form
(completed and signed by the prescriber). The prescriber must write “No
Substitution” or “No Sub” on renewal or subsequent new written prescriptions, and
indicate “No Substitution” on subsequent new oral prescriptions. The dispenser will
be reimbursed the DBP plus a mark-up and the lesser of the posted usual and
customary fee or the ODB dispensing fee minus the applicable ODB co-payment
amount. Where a completed Side Effect Reporting Form is not available at the
pharmacy during an inspection, the difference between the cost of the higher-cost
product and the lowest DBP listed for the interchangeable category will be
recovered.
(ontario.ca, Revision #17; 2026-08-03 ↗)
6.2 Medically Necessary "No Substitution" Claims
The Ministry will provide reimbursement of a higher-cost interchangeable product in
medically necessary circumstances where a patient has experienced a significant
adverse reaction with two (2) lower-cost interchangeable drug products, where
available. When a prescriber identifies a patient for which it is medically necessary
that a higher cost interchangeable product be provided, the prescriber must:
• Complete, sign and forward to the pharmacist a copy of the Health Canada
side effect reporting form for each lower-cost interchangeable drug product
trialed (Side Effect Reporting Form[s]); and
• Write “No Substitution” or “No Sub” on a written prescription or indicate “No
Substitution” to the pharmacist in the case of a verbal prescription.
The prescriber should keep a copy of the completed form in the patient’s record for
future use and reference.
In the case of a written prescription, when the pharmacist or dispensing physician
receives a prescription with the written notation “No Substitution” or “No Sub”,
reimbursement will be provided for the higher-cost interchangeable product only if
the prescription is accompanied by a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed.
This form must be completely filled out noting the details of the adverse reaction
and signed by the prescriber.
In the case of a verbal prescription, the prescriber must satisfy the operator of the
pharmacy or dispensing physician that a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed
has been completed and signed by the prescriber. A written record of this verbal
prescription and the completed Health Canada Side Effect Reporting Form must be
received by the pharmacy prior to claim submission.
Upon receipt, the pharmacist must:
• Fax, submit online or mail the completed and signed form to Health Canada’s
Canada Vigilance Program; and
• Retain his or her copy of the completed and signed Side Effect Reporting
Form.
(ontario.ca, Revision #17; 2026-08-03 ↗)
1 brand, same coverage
Jamp Topiramate Tablets · DIN 02345269
Manufacturer: Jamp Pharma Corporation; listing date 2024-04-30
Health Canada: Marketed since 2024-02-28 · brand JAMP TOPIRAMATE TABLETS · ATC N03AX11 TOPIRAMATE · form Tablet · route Oral · ingredients TOPIRAMATE 100 MG · company Jamp pharma corporation · schedule Prescription
Jamp Topiramate Tablets: Formulary list price $0.4583/unit (unit not stated in source; not the patient's cost)
Ministry pays: $0.4583 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=83069 · Verify on the e-Formulary ↗ (DIN 02345269)
Source record
DIN 02345269: Jamp Topiramate Tablets
Raw flags: sec3=Y
Item: 281200070; group id 446; item number 1117; lccId None; manufacturer id JPC
Source form: Tab; strength: 100mg
Recorded listing: General benefit
Source prices (unrounded): $0.4583; ministry $0.4583
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02345269
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=83069Interchangeable products
AG-Topiramate · DIN 02475944 · $0.4583
Ach-Topiramate · DIN 02395746 · $0.4583
Apo-Topiramate · DIN 02279630 · $0.4583
Auro-Topiramate · DIN 02345838 · $0.4583
Jamp-Topiramate · DIN 02435616 · $0.4583
Mar-Topiramate · DIN 02432102 · $0.4583
Mint-Topiramate · DIN 02315653 · $0.4583
Mylan-Topiramate · DIN 02263378 · $0.4583
NRA-Topiramate · DIN 02538458 · $0.4583
PMS-Topiramate · DIN 02263009 · $0.4583
Ran-Topiramate · DIN 02396084 · $0.4583
Sandoz Topiramate Tablets · DIN 02431815 · $0.4583
Teva-Topiramate · DIN 02248861 · $0.4583
Topamax · DIN 02230894 · $0.4583
Topiramate · DIN 02356864 · $0.4583
Topiramate · DIN 02389487 · $0.4583
Shortage status: no shortage or discontinuation reported (checked 2026-09-13T08:10:21.292534+00:00); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02345269
Shortage record checked 2026-09-13T08:10:21.292534+00:00
Mint-Topiramate · DIN 02315653 · 100mg · tablet
General benefitMarketed · checked 2026-09-02
StatusGeneral benefit
Write on scriptno code needed
Patient paysPatient pays: program not supplied; amount cannot be determined.
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Brand vs generic price
Lowest DBP recovery rule under medically necessary no-substitution claims:
6.2 Medically Necessary "No Substitution" Claims
The Side Effect Reporting Form will not have to be renewed. However, the
pharmacy must maintain a copy of the prescription that contains a direction that
there be no substitution and the required Health Canada Side Effect Reporting Form
(completed and signed by the prescriber). The prescriber must write “No
Substitution” or “No Sub” on renewal or subsequent new written prescriptions, and
indicate “No Substitution” on subsequent new oral prescriptions. The dispenser will
be reimbursed the DBP plus a mark-up and the lesser of the posted usual and
customary fee or the ODB dispensing fee minus the applicable ODB co-payment
amount. Where a completed Side Effect Reporting Form is not available at the
pharmacy during an inspection, the difference between the cost of the higher-cost
product and the lowest DBP listed for the interchangeable category will be
recovered.
(ontario.ca, Revision #17; 2026-08-03 ↗)
6.2 Medically Necessary "No Substitution" Claims
The Ministry will provide reimbursement of a higher-cost interchangeable product in
medically necessary circumstances where a patient has experienced a significant
adverse reaction with two (2) lower-cost interchangeable drug products, where
available. When a prescriber identifies a patient for which it is medically necessary
that a higher cost interchangeable product be provided, the prescriber must:
• Complete, sign and forward to the pharmacist a copy of the Health Canada
side effect reporting form for each lower-cost interchangeable drug product
trialed (Side Effect Reporting Form[s]); and
• Write “No Substitution” or “No Sub” on a written prescription or indicate “No
Substitution” to the pharmacist in the case of a verbal prescription.
The prescriber should keep a copy of the completed form in the patient’s record for
future use and reference.
In the case of a written prescription, when the pharmacist or dispensing physician
receives a prescription with the written notation “No Substitution” or “No Sub”,
reimbursement will be provided for the higher-cost interchangeable product only if
the prescription is accompanied by a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed.
This form must be completely filled out noting the details of the adverse reaction
and signed by the prescriber.
In the case of a verbal prescription, the prescriber must satisfy the operator of the
pharmacy or dispensing physician that a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed
has been completed and signed by the prescriber. A written record of this verbal
prescription and the completed Health Canada Side Effect Reporting Form must be
received by the pharmacy prior to claim submission.
Upon receipt, the pharmacist must:
• Fax, submit online or mail the completed and signed form to Health Canada’s
Canada Vigilance Program; and
• Retain his or her copy of the completed and signed Side Effect Reporting
Form.
(ontario.ca, Revision #17; 2026-08-03 ↗)
1 brand, same coverage
Mint-Topiramate · DIN 02315653
Manufacturer: Mint Pharmaceuticals Inc.; listing date 2009-03-02
Health Canada: Marketed since 2024-06-26 · brand MINT-TOPIRAMATE · ATC N03AX11 TOPIRAMATE · form Tablet · route Oral · ingredients TOPIRAMATE 100 MG · company Mint pharmaceuticals inc · schedule Prescription
Mint-Topiramate: Formulary list price $0.4583/unit (unit not stated in source; not the patient's cost)
Ministry pays: $0.4583 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=80118 · Verify on the e-Formulary ↗ (DIN 02315653)
Source record
DIN 02315653: Mint-Topiramate
Raw flags: sec3=Y
Item: 281200070; group id 446; item number 1117; lccId None; manufacturer id MIN
Source form: Tab; strength: 100mg
Recorded listing: General benefit
Source prices (unrounded): $0.4583; ministry $0.4583
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02315653
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=80118Interchangeable products
AG-Topiramate · DIN 02475944 · $0.4583
Ach-Topiramate · DIN 02395746 · $0.4583
Apo-Topiramate · DIN 02279630 · $0.4583
Auro-Topiramate · DIN 02345838 · $0.4583
Jamp Topiramate Tablets · DIN 02345269 · $0.4583
Jamp-Topiramate · DIN 02435616 · $0.4583
Mar-Topiramate · DIN 02432102 · $0.4583
Mylan-Topiramate · DIN 02263378 · $0.4583
NRA-Topiramate · DIN 02538458 · $0.4583
PMS-Topiramate · DIN 02263009 · $0.4583
Ran-Topiramate · DIN 02396084 · $0.4583
Sandoz Topiramate Tablets · DIN 02431815 · $0.4583
Teva-Topiramate · DIN 02248861 · $0.4583
Topamax · DIN 02230894 · $0.4583
Topiramate · DIN 02356864 · $0.4583
Topiramate · DIN 02389487 · $0.4583
Shortage status: resolved shortage (ended 2024-10-21); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02315653
Shortage record checked 2026-09-13T08:10:21.292534+00:00
Mylan-Topiramate · DIN 02263378 · 100mg · tablet
General benefitMarketed · checked 2026-09-02
StatusGeneral benefit
Write on scriptno code needed
Patient paysPatient pays: program not supplied; amount cannot be determined.
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Brand vs generic price
Lowest DBP recovery rule under medically necessary no-substitution claims:
6.2 Medically Necessary "No Substitution" Claims
The Side Effect Reporting Form will not have to be renewed. However, the
pharmacy must maintain a copy of the prescription that contains a direction that
there be no substitution and the required Health Canada Side Effect Reporting Form
(completed and signed by the prescriber). The prescriber must write “No
Substitution” or “No Sub” on renewal or subsequent new written prescriptions, and
indicate “No Substitution” on subsequent new oral prescriptions. The dispenser will
be reimbursed the DBP plus a mark-up and the lesser of the posted usual and
customary fee or the ODB dispensing fee minus the applicable ODB co-payment
amount. Where a completed Side Effect Reporting Form is not available at the
pharmacy during an inspection, the difference between the cost of the higher-cost
product and the lowest DBP listed for the interchangeable category will be
recovered.
(ontario.ca, Revision #17; 2026-08-03 ↗)
6.2 Medically Necessary "No Substitution" Claims
The Ministry will provide reimbursement of a higher-cost interchangeable product in
medically necessary circumstances where a patient has experienced a significant
adverse reaction with two (2) lower-cost interchangeable drug products, where
available. When a prescriber identifies a patient for which it is medically necessary
that a higher cost interchangeable product be provided, the prescriber must:
• Complete, sign and forward to the pharmacist a copy of the Health Canada
side effect reporting form for each lower-cost interchangeable drug product
trialed (Side Effect Reporting Form[s]); and
• Write “No Substitution” or “No Sub” on a written prescription or indicate “No
Substitution” to the pharmacist in the case of a verbal prescription.
The prescriber should keep a copy of the completed form in the patient’s record for
future use and reference.
In the case of a written prescription, when the pharmacist or dispensing physician
receives a prescription with the written notation “No Substitution” or “No Sub”,
reimbursement will be provided for the higher-cost interchangeable product only if
the prescription is accompanied by a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed.
This form must be completely filled out noting the details of the adverse reaction
and signed by the prescriber.
In the case of a verbal prescription, the prescriber must satisfy the operator of the
pharmacy or dispensing physician that a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed
has been completed and signed by the prescriber. A written record of this verbal
prescription and the completed Health Canada Side Effect Reporting Form must be
received by the pharmacy prior to claim submission.
Upon receipt, the pharmacist must:
• Fax, submit online or mail the completed and signed form to Health Canada’s
Canada Vigilance Program; and
• Retain his or her copy of the completed and signed Side Effect Reporting
Form.
(ontario.ca, Revision #17; 2026-08-03 ↗)
1 brand, same coverage
Mylan-Topiramate · DIN 02263378
Manufacturer: Mylan Pharmaceuticals ULC; listing date 2005-11-08
Health Canada: Marketed since 2010-02-04 · brand MYLAN-TOPIRAMATE · ATC N03AX11 TOPIRAMATE · form Tablet · route Oral · ingredients TOPIRAMATE 100 MG · company Mylan pharmaceuticals ulc · schedule Prescription
Mylan-Topiramate: Formulary list price $0.4583/unit (unit not stated in source; not the patient's cost)
Ministry pays: $0.4583 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=74875 · Verify on the e-Formulary ↗ (DIN 02263378)
Source record
DIN 02263378: Mylan-Topiramate
Raw flags: sec3=Y
Item: 281200070; group id 446; item number 1117; lccId None; manufacturer id MYL
Source form: Tab; strength: 100mg
Recorded listing: General benefit
Source prices (unrounded): $0.4583; ministry $0.4583
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02263378
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=74875Interchangeable products
AG-Topiramate · DIN 02475944 · $0.4583
Ach-Topiramate · DIN 02395746 · $0.4583
Apo-Topiramate · DIN 02279630 · $0.4583
Auro-Topiramate · DIN 02345838 · $0.4583
Jamp Topiramate Tablets · DIN 02345269 · $0.4583
Jamp-Topiramate · DIN 02435616 · $0.4583
Mar-Topiramate · DIN 02432102 · $0.4583
Mint-Topiramate · DIN 02315653 · $0.4583
NRA-Topiramate · DIN 02538458 · $0.4583
PMS-Topiramate · DIN 02263009 · $0.4583
Ran-Topiramate · DIN 02396084 · $0.4583
Sandoz Topiramate Tablets · DIN 02431815 · $0.4583
Teva-Topiramate · DIN 02248861 · $0.4583
Topamax · DIN 02230894 · $0.4583
Topiramate · DIN 02356864 · $0.4583
Topiramate · DIN 02389487 · $0.4583
Shortage status: resolved shortage (ended 2024-05-14); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02263378
Shortage record checked 2026-09-13T08:10:21.292534+00:00
NRA-Topiramate · DIN 02538458 · 100mg · tablet
General benefitMarketed · checked 2026-09-02
StatusGeneral benefit
Write on scriptno code needed
Patient paysPatient pays: program not supplied; amount cannot be determined.
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Brand vs generic price
Lowest DBP recovery rule under medically necessary no-substitution claims:
6.2 Medically Necessary "No Substitution" Claims
The Side Effect Reporting Form will not have to be renewed. However, the
pharmacy must maintain a copy of the prescription that contains a direction that
there be no substitution and the required Health Canada Side Effect Reporting Form
(completed and signed by the prescriber). The prescriber must write “No
Substitution” or “No Sub” on renewal or subsequent new written prescriptions, and
indicate “No Substitution” on subsequent new oral prescriptions. The dispenser will
be reimbursed the DBP plus a mark-up and the lesser of the posted usual and
customary fee or the ODB dispensing fee minus the applicable ODB co-payment
amount. Where a completed Side Effect Reporting Form is not available at the
pharmacy during an inspection, the difference between the cost of the higher-cost
product and the lowest DBP listed for the interchangeable category will be
recovered.
(ontario.ca, Revision #17; 2026-08-03 ↗)
6.2 Medically Necessary "No Substitution" Claims
The Ministry will provide reimbursement of a higher-cost interchangeable product in
medically necessary circumstances where a patient has experienced a significant
adverse reaction with two (2) lower-cost interchangeable drug products, where
available. When a prescriber identifies a patient for which it is medically necessary
that a higher cost interchangeable product be provided, the prescriber must:
• Complete, sign and forward to the pharmacist a copy of the Health Canada
side effect reporting form for each lower-cost interchangeable drug product
trialed (Side Effect Reporting Form[s]); and
• Write “No Substitution” or “No Sub” on a written prescription or indicate “No
Substitution” to the pharmacist in the case of a verbal prescription.
The prescriber should keep a copy of the completed form in the patient’s record for
future use and reference.
In the case of a written prescription, when the pharmacist or dispensing physician
receives a prescription with the written notation “No Substitution” or “No Sub”,
reimbursement will be provided for the higher-cost interchangeable product only if
the prescription is accompanied by a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed.
This form must be completely filled out noting the details of the adverse reaction
and signed by the prescriber.
In the case of a verbal prescription, the prescriber must satisfy the operator of the
pharmacy or dispensing physician that a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed
has been completed and signed by the prescriber. A written record of this verbal
prescription and the completed Health Canada Side Effect Reporting Form must be
received by the pharmacy prior to claim submission.
Upon receipt, the pharmacist must:
• Fax, submit online or mail the completed and signed form to Health Canada’s
Canada Vigilance Program; and
• Retain his or her copy of the completed and signed Side Effect Reporting
Form.
(ontario.ca, Revision #17; 2026-08-03 ↗)
1 brand, same coverage
NRA-Topiramate · DIN 02538458
Manufacturer: Nora Pharma; listing date 2024-04-30
Health Canada: Marketed since 2024-01-11 · brand NRA-TOPIRAMATE · ATC N03AX11 TOPIRAMATE · form Tablet · route Oral · ingredients TOPIRAMATE 100 MG · company Nora pharma inc · schedule Prescription
NRA-Topiramate: Formulary list price $0.4583/unit (unit not stated in source; not the patient's cost)
Ministry pays: $0.4583 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=102717 · Verify on the e-Formulary ↗ (DIN 02538458)
Source record
DIN 02538458: NRA-Topiramate
Raw flags: sec3=Y
Item: 281200070; group id 446; item number 1117; lccId None; manufacturer id NRA
Source form: Tab; strength: 100mg
Recorded listing: General benefit
Source prices (unrounded): $0.4583; ministry $0.4583
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02538458
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=102717Interchangeable products
AG-Topiramate · DIN 02475944 · $0.4583
Ach-Topiramate · DIN 02395746 · $0.4583
Apo-Topiramate · DIN 02279630 · $0.4583
Auro-Topiramate · DIN 02345838 · $0.4583
Jamp Topiramate Tablets · DIN 02345269 · $0.4583
Jamp-Topiramate · DIN 02435616 · $0.4583
Mar-Topiramate · DIN 02432102 · $0.4583
Mint-Topiramate · DIN 02315653 · $0.4583
Mylan-Topiramate · DIN 02263378 · $0.4583
PMS-Topiramate · DIN 02263009 · $0.4583
Ran-Topiramate · DIN 02396084 · $0.4583
Sandoz Topiramate Tablets · DIN 02431815 · $0.4583
Teva-Topiramate · DIN 02248861 · $0.4583
Topamax · DIN 02230894 · $0.4583
Topiramate · DIN 02356864 · $0.4583
Topiramate · DIN 02389487 · $0.4583
Shortage status: no shortage or discontinuation reported (checked 2026-09-13T08:10:21.292534+00:00); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02538458
Shortage record checked 2026-09-13T08:10:21.292534+00:00
PMS-Topiramate · DIN 02263009 · 100mg · tablet
General benefitMarketed · checked 2026-09-02
StatusGeneral benefit
Write on scriptno code needed
Patient paysPatient pays: program not supplied; amount cannot be determined.
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Brand vs generic price
Lowest DBP recovery rule under medically necessary no-substitution claims:
6.2 Medically Necessary "No Substitution" Claims
The Side Effect Reporting Form will not have to be renewed. However, the
pharmacy must maintain a copy of the prescription that contains a direction that
there be no substitution and the required Health Canada Side Effect Reporting Form
(completed and signed by the prescriber). The prescriber must write “No
Substitution” or “No Sub” on renewal or subsequent new written prescriptions, and
indicate “No Substitution” on subsequent new oral prescriptions. The dispenser will
be reimbursed the DBP plus a mark-up and the lesser of the posted usual and
customary fee or the ODB dispensing fee minus the applicable ODB co-payment
amount. Where a completed Side Effect Reporting Form is not available at the
pharmacy during an inspection, the difference between the cost of the higher-cost
product and the lowest DBP listed for the interchangeable category will be
recovered.
(ontario.ca, Revision #17; 2026-08-03 ↗)
6.2 Medically Necessary "No Substitution" Claims
The Ministry will provide reimbursement of a higher-cost interchangeable product in
medically necessary circumstances where a patient has experienced a significant
adverse reaction with two (2) lower-cost interchangeable drug products, where
available. When a prescriber identifies a patient for which it is medically necessary
that a higher cost interchangeable product be provided, the prescriber must:
• Complete, sign and forward to the pharmacist a copy of the Health Canada
side effect reporting form for each lower-cost interchangeable drug product
trialed (Side Effect Reporting Form[s]); and
• Write “No Substitution” or “No Sub” on a written prescription or indicate “No
Substitution” to the pharmacist in the case of a verbal prescription.
The prescriber should keep a copy of the completed form in the patient’s record for
future use and reference.
In the case of a written prescription, when the pharmacist or dispensing physician
receives a prescription with the written notation “No Substitution” or “No Sub”,
reimbursement will be provided for the higher-cost interchangeable product only if
the prescription is accompanied by a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed.
This form must be completely filled out noting the details of the adverse reaction
and signed by the prescriber.
In the case of a verbal prescription, the prescriber must satisfy the operator of the
pharmacy or dispensing physician that a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed
has been completed and signed by the prescriber. A written record of this verbal
prescription and the completed Health Canada Side Effect Reporting Form must be
received by the pharmacy prior to claim submission.
Upon receipt, the pharmacist must:
• Fax, submit online or mail the completed and signed form to Health Canada’s
Canada Vigilance Program; and
• Retain his or her copy of the completed and signed Side Effect Reporting
Form.
(ontario.ca, Revision #17; 2026-08-03 ↗)
1 brand, same coverage
PMS-Topiramate · DIN 02263009
Manufacturer: Pharmascience Inc.; listing date 2005-11-08
Health Canada: Marketed since 2005-09-14 · brand PMS-TOPIRAMATE · ATC N03AX11 TOPIRAMATE · form Tablet · route Oral · ingredients TOPIRAMATE 100 MG · company Pharmascience inc · schedule Prescription
PMS-Topiramate: Formulary list price $0.4583/unit (unit not stated in source; not the patient's cost)
Ministry pays: $0.4583 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=74841 · Verify on the e-Formulary ↗ (DIN 02263009)
Source record
DIN 02263009: PMS-Topiramate
Raw flags: sec3=Y
Item: 281200070; group id 446; item number 1117; lccId None; manufacturer id PMS
Source form: Tab; strength: 100mg
Recorded listing: General benefit
Source prices (unrounded): $0.4583; ministry $0.4583
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02263009
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=74841Interchangeable products
AG-Topiramate · DIN 02475944 · $0.4583
Ach-Topiramate · DIN 02395746 · $0.4583
Apo-Topiramate · DIN 02279630 · $0.4583
Auro-Topiramate · DIN 02345838 · $0.4583
Jamp Topiramate Tablets · DIN 02345269 · $0.4583
Jamp-Topiramate · DIN 02435616 · $0.4583
Mar-Topiramate · DIN 02432102 · $0.4583
Mint-Topiramate · DIN 02315653 · $0.4583
Mylan-Topiramate · DIN 02263378 · $0.4583
NRA-Topiramate · DIN 02538458 · $0.4583
Ran-Topiramate · DIN 02396084 · $0.4583
Sandoz Topiramate Tablets · DIN 02431815 · $0.4583
Teva-Topiramate · DIN 02248861 · $0.4583
Topamax · DIN 02230894 · $0.4583
Topiramate · DIN 02356864 · $0.4583
Topiramate · DIN 02389487 · $0.4583
Shortage status: resolved shortage (ended 2026-02-25); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02263009
Shortage record checked 2026-09-13T08:10:21.292534+00:00
Teva-Topiramate · DIN 02248861 · 100mg · tablet
General benefitMarketed · checked 2026-09-02
StatusGeneral benefit
Write on scriptno code needed
Patient paysPatient pays: program not supplied; amount cannot be determined.
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Brand vs generic price
Lowest DBP recovery rule under medically necessary no-substitution claims:
6.2 Medically Necessary "No Substitution" Claims
The Side Effect Reporting Form will not have to be renewed. However, the
pharmacy must maintain a copy of the prescription that contains a direction that
there be no substitution and the required Health Canada Side Effect Reporting Form
(completed and signed by the prescriber). The prescriber must write “No
Substitution” or “No Sub” on renewal or subsequent new written prescriptions, and
indicate “No Substitution” on subsequent new oral prescriptions. The dispenser will
be reimbursed the DBP plus a mark-up and the lesser of the posted usual and
customary fee or the ODB dispensing fee minus the applicable ODB co-payment
amount. Where a completed Side Effect Reporting Form is not available at the
pharmacy during an inspection, the difference between the cost of the higher-cost
product and the lowest DBP listed for the interchangeable category will be
recovered.
(ontario.ca, Revision #17; 2026-08-03 ↗)
6.2 Medically Necessary "No Substitution" Claims
The Ministry will provide reimbursement of a higher-cost interchangeable product in
medically necessary circumstances where a patient has experienced a significant
adverse reaction with two (2) lower-cost interchangeable drug products, where
available. When a prescriber identifies a patient for which it is medically necessary
that a higher cost interchangeable product be provided, the prescriber must:
• Complete, sign and forward to the pharmacist a copy of the Health Canada
side effect reporting form for each lower-cost interchangeable drug product
trialed (Side Effect Reporting Form[s]); and
• Write “No Substitution” or “No Sub” on a written prescription or indicate “No
Substitution” to the pharmacist in the case of a verbal prescription.
The prescriber should keep a copy of the completed form in the patient’s record for
future use and reference.
In the case of a written prescription, when the pharmacist or dispensing physician
receives a prescription with the written notation “No Substitution” or “No Sub”,
reimbursement will be provided for the higher-cost interchangeable product only if
the prescription is accompanied by a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed.
This form must be completely filled out noting the details of the adverse reaction
and signed by the prescriber.
In the case of a verbal prescription, the prescriber must satisfy the operator of the
pharmacy or dispensing physician that a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed
has been completed and signed by the prescriber. A written record of this verbal
prescription and the completed Health Canada Side Effect Reporting Form must be
received by the pharmacy prior to claim submission.
Upon receipt, the pharmacist must:
• Fax, submit online or mail the completed and signed form to Health Canada’s
Canada Vigilance Program; and
• Retain his or her copy of the completed and signed Side Effect Reporting
Form.
(ontario.ca, Revision #17; 2026-08-03 ↗)
1 brand, same coverage
Teva-Topiramate · DIN 02248861
Manufacturer: Teva Canada Limited; listing date 2005-11-08
Health Canada: Marketed since 2011-05-07 · brand TEVA-TOPIRAMATE · ATC N03AX11 TOPIRAMATE · form Tablet · route Oral · ingredients TOPIRAMATE 100 MG · company Teva canada limited · schedule Prescription
Teva-Topiramate: Formulary list price $0.4583/unit (unit not stated in source; not the patient's cost)
Ministry pays: $0.4583 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=73233 · Verify on the e-Formulary ↗ (DIN 02248861)
Source record
DIN 02248861: Teva-Topiramate
Raw flags: sec3=Y
Item: 281200070; group id 446; item number 1117; lccId None; manufacturer id TEV
Source form: Tab; strength: 100mg
Recorded listing: General benefit
Source prices (unrounded): $0.4583; ministry $0.4583
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02248861
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=73233Interchangeable products
AG-Topiramate · DIN 02475944 · $0.4583
Ach-Topiramate · DIN 02395746 · $0.4583
Apo-Topiramate · DIN 02279630 · $0.4583
Auro-Topiramate · DIN 02345838 · $0.4583
Jamp Topiramate Tablets · DIN 02345269 · $0.4583
Jamp-Topiramate · DIN 02435616 · $0.4583
Mar-Topiramate · DIN 02432102 · $0.4583
Mint-Topiramate · DIN 02315653 · $0.4583
Mylan-Topiramate · DIN 02263378 · $0.4583
NRA-Topiramate · DIN 02538458 · $0.4583
PMS-Topiramate · DIN 02263009 · $0.4583
Ran-Topiramate · DIN 02396084 · $0.4583
Sandoz Topiramate Tablets · DIN 02431815 · $0.4583
Topamax · DIN 02230894 · $0.4583
Topiramate · DIN 02356864 · $0.4583
Topiramate · DIN 02389487 · $0.4583
Shortage status: resolved shortage (ended 2025-08-07); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02248861
Shortage record checked 2026-09-13T08:10:21.292534+00:00
Topiramate · DIN 02356864 · 100mg · tablet
General benefitMarketed · checked 2026-09-02
StatusGeneral benefit
Write on scriptno code needed
Patient paysPatient pays: program not supplied; amount cannot be determined.
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Brand vs generic price
Lowest DBP recovery rule under medically necessary no-substitution claims:
6.2 Medically Necessary "No Substitution" Claims
The Side Effect Reporting Form will not have to be renewed. However, the
pharmacy must maintain a copy of the prescription that contains a direction that
there be no substitution and the required Health Canada Side Effect Reporting Form
(completed and signed by the prescriber). The prescriber must write “No
Substitution” or “No Sub” on renewal or subsequent new written prescriptions, and
indicate “No Substitution” on subsequent new oral prescriptions. The dispenser will
be reimbursed the DBP plus a mark-up and the lesser of the posted usual and
customary fee or the ODB dispensing fee minus the applicable ODB co-payment
amount. Where a completed Side Effect Reporting Form is not available at the
pharmacy during an inspection, the difference between the cost of the higher-cost
product and the lowest DBP listed for the interchangeable category will be
recovered.
(ontario.ca, Revision #17; 2026-08-03 ↗)
6.2 Medically Necessary "No Substitution" Claims
The Ministry will provide reimbursement of a higher-cost interchangeable product in
medically necessary circumstances where a patient has experienced a significant
adverse reaction with two (2) lower-cost interchangeable drug products, where
available. When a prescriber identifies a patient for which it is medically necessary
that a higher cost interchangeable product be provided, the prescriber must:
• Complete, sign and forward to the pharmacist a copy of the Health Canada
side effect reporting form for each lower-cost interchangeable drug product
trialed (Side Effect Reporting Form[s]); and
• Write “No Substitution” or “No Sub” on a written prescription or indicate “No
Substitution” to the pharmacist in the case of a verbal prescription.
The prescriber should keep a copy of the completed form in the patient’s record for
future use and reference.
In the case of a written prescription, when the pharmacist or dispensing physician
receives a prescription with the written notation “No Substitution” or “No Sub”,
reimbursement will be provided for the higher-cost interchangeable product only if
the prescription is accompanied by a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed.
This form must be completely filled out noting the details of the adverse reaction
and signed by the prescriber.
In the case of a verbal prescription, the prescriber must satisfy the operator of the
pharmacy or dispensing physician that a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed
has been completed and signed by the prescriber. A written record of this verbal
prescription and the completed Health Canada Side Effect Reporting Form must be
received by the pharmacy prior to claim submission.
Upon receipt, the pharmacist must:
• Fax, submit online or mail the completed and signed form to Health Canada’s
Canada Vigilance Program; and
• Retain his or her copy of the completed and signed Side Effect Reporting
Form.
(ontario.ca, Revision #17; 2026-08-03 ↗)
1 brand, same coverage
Topiramate · DIN 02356864
Manufacturer: Sanis Health Inc.; listing date 2011-08-04
Health Canada: Marketed since 2010-10-06 · brand TOPIRAMATE · ATC N03AX11 TOPIRAMATE · form Tablet · route Oral · ingredients TOPIRAMATE 100 MG · company Sanis health inc · schedule Prescription
Topiramate: Formulary list price $0.4583/unit (unit not stated in source; not the patient's cost)
Ministry pays: $0.4583 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=84198 · Verify on the e-Formulary ↗ (DIN 02356864)
Source record
DIN 02356864: Topiramate
Raw flags: sec3=Y
Item: 281200070; group id 446; item number 1117; lccId None; manufacturer id SAI
Source form: Tab; strength: 100mg
Recorded listing: General benefit
Source prices (unrounded): $0.4583; ministry $0.4583
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02356864
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=84198Interchangeable products
AG-Topiramate · DIN 02475944 · $0.4583
Ach-Topiramate · DIN 02395746 · $0.4583
Apo-Topiramate · DIN 02279630 · $0.4583
Auro-Topiramate · DIN 02345838 · $0.4583
Jamp Topiramate Tablets · DIN 02345269 · $0.4583
Jamp-Topiramate · DIN 02435616 · $0.4583
Mar-Topiramate · DIN 02432102 · $0.4583
Mint-Topiramate · DIN 02315653 · $0.4583
Mylan-Topiramate · DIN 02263378 · $0.4583
NRA-Topiramate · DIN 02538458 · $0.4583
PMS-Topiramate · DIN 02263009 · $0.4583
Ran-Topiramate · DIN 02396084 · $0.4583
Sandoz Topiramate Tablets · DIN 02431815 · $0.4583
Teva-Topiramate · DIN 02248861 · $0.4583
Topamax · DIN 02230894 · $0.4583
Topiramate · DIN 02389487 · $0.4583
Shortage status: anticipated shortage (last updated 2026-07-22); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02356864
Shortage record checked 2026-09-13T08:10:21.292534+00:00
Topiramate · DIN 02389487 · 100mg · tablet
General benefitMarketed · checked 2026-09-02
StatusGeneral benefit
Write on scriptno code needed
Patient paysPatient pays: program not supplied; amount cannot be determined.
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Brand vs generic price
Lowest DBP recovery rule under medically necessary no-substitution claims:
6.2 Medically Necessary "No Substitution" Claims
The Side Effect Reporting Form will not have to be renewed. However, the
pharmacy must maintain a copy of the prescription that contains a direction that
there be no substitution and the required Health Canada Side Effect Reporting Form
(completed and signed by the prescriber). The prescriber must write “No
Substitution” or “No Sub” on renewal or subsequent new written prescriptions, and
indicate “No Substitution” on subsequent new oral prescriptions. The dispenser will
be reimbursed the DBP plus a mark-up and the lesser of the posted usual and
customary fee or the ODB dispensing fee minus the applicable ODB co-payment
amount. Where a completed Side Effect Reporting Form is not available at the
pharmacy during an inspection, the difference between the cost of the higher-cost
product and the lowest DBP listed for the interchangeable category will be
recovered.
(ontario.ca, Revision #17; 2026-08-03 ↗)
6.2 Medically Necessary "No Substitution" Claims
The Ministry will provide reimbursement of a higher-cost interchangeable product in
medically necessary circumstances where a patient has experienced a significant
adverse reaction with two (2) lower-cost interchangeable drug products, where
available. When a prescriber identifies a patient for which it is medically necessary
that a higher cost interchangeable product be provided, the prescriber must:
• Complete, sign and forward to the pharmacist a copy of the Health Canada
side effect reporting form for each lower-cost interchangeable drug product
trialed (Side Effect Reporting Form[s]); and
• Write “No Substitution” or “No Sub” on a written prescription or indicate “No
Substitution” to the pharmacist in the case of a verbal prescription.
The prescriber should keep a copy of the completed form in the patient’s record for
future use and reference.
In the case of a written prescription, when the pharmacist or dispensing physician
receives a prescription with the written notation “No Substitution” or “No Sub”,
reimbursement will be provided for the higher-cost interchangeable product only if
the prescription is accompanied by a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed.
This form must be completely filled out noting the details of the adverse reaction
and signed by the prescriber.
In the case of a verbal prescription, the prescriber must satisfy the operator of the
pharmacy or dispensing physician that a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed
has been completed and signed by the prescriber. A written record of this verbal
prescription and the completed Health Canada Side Effect Reporting Form must be
received by the pharmacy prior to claim submission.
Upon receipt, the pharmacist must:
• Fax, submit online or mail the completed and signed form to Health Canada’s
Canada Vigilance Program; and
• Retain his or her copy of the completed and signed Side Effect Reporting
Form.
(ontario.ca, Revision #17; 2026-08-03 ↗)
1 brand, same coverage
Topiramate · DIN 02389487
Manufacturer: Sivem Pharmaceuticals ULC; listing date 2020-08-28
Health Canada: Marketed since 2018-05-04 · brand TOPIRAMATE · ATC N03AX11 TOPIRAMATE · form Tablet · route Oral · ingredients TOPIRAMATE 100 MG · company Sivem pharmaceuticals ulc · schedule Prescription
Topiramate: Formulary list price $0.4583/unit (unit not stated in source; not the patient's cost)
Ministry pays: $0.4583 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=87499 · Verify on the e-Formulary ↗ (DIN 02389487)
Source record
DIN 02389487: Topiramate
Raw flags: sec3=Y
Item: 281200070; group id 446; item number 1117; lccId None; manufacturer id SIV
Source form: Tab; strength: 100mg
Recorded listing: General benefit
Source prices (unrounded): $0.4583; ministry $0.4583
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02389487
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=87499Interchangeable products
AG-Topiramate · DIN 02475944 · $0.4583
Ach-Topiramate · DIN 02395746 · $0.4583
Apo-Topiramate · DIN 02279630 · $0.4583
Auro-Topiramate · DIN 02345838 · $0.4583
Jamp Topiramate Tablets · DIN 02345269 · $0.4583
Jamp-Topiramate · DIN 02435616 · $0.4583
Mar-Topiramate · DIN 02432102 · $0.4583
Mint-Topiramate · DIN 02315653 · $0.4583
Mylan-Topiramate · DIN 02263378 · $0.4583
NRA-Topiramate · DIN 02538458 · $0.4583
PMS-Topiramate · DIN 02263009 · $0.4583
Ran-Topiramate · DIN 02396084 · $0.4583
Sandoz Topiramate Tablets · DIN 02431815 · $0.4583
Teva-Topiramate · DIN 02248861 · $0.4583
Topamax · DIN 02230894 · $0.4583
Topiramate · DIN 02356864 · $0.4583
Shortage status: resolved shortage (ended 2018-05-18); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02389487
Shortage record checked 2026-09-13T08:10:21.292534+00:00
Jamp-Topiramate Tablets · DIN 02544377 · 50mg · tablet
Off-Formulary Interchangeable, not an ODB benefitMarketed · checked 2026-09-02
StatusOff-Formulary Interchangeable, not an ODB benefit
Write on scriptnot a benefit; no Exceptional Access criteria on record; see alternatives
Patient paysPatient pays: program not supplied; amount cannot be determined.
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
1 brand, same coverage
Jamp-Topiramate Tablets · DIN 02544377
Manufacturer: Jamp Pharma Corporation; listing date 2024-11-29
Health Canada: Marketed since 2024-08-28 · brand JAMP TOPIRAMATE TABLETS · ATC N03AX11 TOPIRAMATE · form Tablet · route Oral · ingredients TOPIRAMATE 50 MG · company Jamp pharma corporation · schedule Prescription
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=103293 · Verify on the e-Formulary ↗ (DIN 02544377)
Source record
DIN 02544377: Jamp-Topiramate Tablets
Raw flags: notABenefit=Y, sec3=Y, sec3b=Y
Item: 281200188; group id 446; item number 1115; lccId None; manufacturer id JPC
Source form: Tab; strength: 50mg
Recorded listing: Off-Formulary Interchangeable, not an ODB benefit
Source prices (unrounded): $1.2434; ministry not recorded
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02544377
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=103293Interchangeable products
PMS-Topiramate · DIN 02312085 · not recorded
Topamax · DIN 02231385 · not recorded
Shortage status: no shortage or discontinuation reported (checked 2026-09-13T08:10:21.292534+00:00); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02544377
Shortage record checked 2026-09-13T08:10:21.292534+00:00
PMS-Topiramate · DIN 02312085 · 50mg · tablet
Off-Formulary Interchangeable, not an ODB benefitMarketed · checked 2026-09-02
StatusOff-Formulary Interchangeable, not an ODB benefit
Write on scriptnot a benefit; no Exceptional Access criteria on record; see alternatives
Patient paysPatient pays: program not supplied; amount cannot be determined.
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
1 brand, same coverage
PMS-Topiramate · DIN 02312085
Manufacturer: Pharmascience Inc.; listing date 2025-02-28
Health Canada: Marketed since 2008-06-17 · brand PMS-TOPIRAMATE · ATC N03AX11 TOPIRAMATE · form Tablet · route Oral · ingredients TOPIRAMATE 50 MG · company Pharmascience inc · schedule Prescription
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=79760 · Verify on the e-Formulary ↗ (DIN 02312085)
Source record
DIN 02312085: PMS-Topiramate
Raw flags: notABenefit=Y, sec3=Y, sec3b=Y
Item: 281200188; group id 446; item number 1115; lccId None; manufacturer id PMS
Source form: Tab; strength: 50mg
Recorded listing: Off-Formulary Interchangeable, not an ODB benefit
Source prices (unrounded): $1.2434; ministry not recorded
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02312085
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=79760Interchangeable products
Jamp-Topiramate Tablets · DIN 02544377 · not recorded
Topamax · DIN 02231385 · not recorded
Shortage status: active shortage (reported 2026-08-21, estimated to end 2026-10-06, last updated 2026-08-26); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02312085
Shortage record checked 2026-09-13T08:10:21.292534+00:00
Other drugs in the same formulary class (28:12 Anticonvulsants) and how they are covered
Matched class: 28:12 Anticonvulsants
Drug-class inventory only. Lists recorded Ontario formulary products, not every Canadian medication; does not recommend treatment.
Covered without a code on the Ontario formulary: CLONAZEPAM, DIVALPROEX SODIUM, ETHOSUXIMIDE, LAMOTRIGINE, VALPROATE SODIUM
Some products covered without a code (check the product listing): CARBAMAZEPINE, GABAPENTIN, PHENYTOIN (DIPHENYLHYDANTOIN), PHENYTOIN (DIPHENYLHYDANTOIN) SODIUM, PREGABALIN, PRIMIDONE, VALPROIC ACID
28:12 Anticonvulsants
· 4 products · General benefit; DIN status E (meaning unconfirmed); confirm discontinuation/availability with Health Canada (2), General benefit (2) · strengths: 6mg/mL, 25mg/mL, 50mg · O/L, Tab
1. Indications
Epilepsy
TOPAMAX® (topiramate) is indicated:
• as monotherapy for the management of patients (adults and children six years and older) with
newly diagnosed epilepsy.
• as adjunctive therapy for the management of patients (adults and children two years and older)
with epilepsy who are not satisfactorily controlled with conventional therapy.
Migraine Prophylaxis
Topamax is indicated in adults for the prophylaxis of migraine headache. Prophylactic treatment of
migraine may be considered in situations such as: adults experiencing four or more migraine attacks per
month who fail to respond adequately to acute abortive therapy; recurring attacks that significantly
interfere with the patient’s daily routine; a pattern of increasing migraine attacks over time, with the
risk of developing rebound headache from acute abortive therapies; or failure of, or contraindication to,
or troublesome side effects from acute abortive medications. Continuing therapy should be reviewed
every six months. Topamax should not be used in the acute treatment of migraine attacks. Safety and
efficacy of topiramate in the management or prevention of cluster headache…
https://pdf.hres.ca/dpd_pm/00081153.PDF
PM date: 2025-07-23
Source product: TOPAMAX; DIN 02239907; fetched 2026-09-10
Product monograph posted by Health Canada; excerpt for lookup only.
Availability
PMS-Topiramate · DIN 02312085
Shortage status: active shortage (reported 2026-08-21, estimated to end 2026-10-06, last updated 2026-08-26); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02312085
For Jamp-Topiramate Tablets, PMS-Topiramate: no applicable EAP criteria are held and no ODB benefit is established. These policies do not establish coverage.
For rare, immediately life-, limb- or organ-threatening circumstances, the Compassionate Review Policy may consider an unfunded drug or indication, subject to its criteria and without bypassing the drug review process. Compassionate Review Policy
Compassionate Review Policy: source quote
Where there are rare clinical circumstances in immediately life, limb, or organ-threatening conditions, the Executive Officer will also consider requests for drugs or indications in situations where there has not been a decision by the Executive Officer to provide funding of the drug or indication as part of the Ontario Drug Benefit program (and the EAP), and the drug or indication requested would not circumvent the established review process for new drugs or indications as part of the drug submission process for listing within the Ontario Drug Benefit program. Requests must meet the criteria for the Compassionate Review Policy.
For cancer drugs, Case-by-Case Review considers rare, immediately life-threatening circumstances when no satisfactory funded treatment exists; its criteria and application process apply. Case-by-Case Review (cancer drugs)
Case-by-Case Review (cancer drugs): source quote
Note: Requests for cancer drugs are considered under the Case-by-Case Review Program (CBCRP) which is administered by Ontario Health (Cancer Care Ontario) on behalf of the Ministry of Health. The CBCRP considers funding requests for drugs (both oral therapies and injectable drugs) for the treatment of cancer in patients who have a rare clinical circumstance that is immediately life-threatening (death is likely within a matter of months) and who require treatment with an unfunded drug, because there is no other satisfactory and funded treatment. Please refer to the Ontario Health website for information on the application process, FAQs, eligibility criteria and program policies.