BRIVARACETAM
All strengths: Limited Use — Reason for Use code 548 required; same patient cost rules
Shared coverage and patient cost rules
StatusLimited Use — Reason for Use code 548 required
Patient paysPatient pays: program not supplied; amount cannot be determined.
Other products in the same Health Canada class (N03AX) — coverage varies; not interchangeable
- Lamotrigine (Lamictal): general benefit
- Topiramate (Topamax Sprinkle): general benefit, Limited Use 321, Not a benefit
- Cenobamate (Xcopri): limited Use 719
- Lacosamide (Vimpat): limited Use 430
- Levetiracetam (PDP-Levetiracetam): limited Use 473, Limited Use 640, 705
- Perampanel (Fycompa): limited Use 430, 564
14 more in the class list below
Apo-Brivaracetam · DIN 02538679 · 10mg · tablet
Limited Use — Reason for Use code 548 requiredMarketed · checked 2026-09-02
Write on scriptLU code 548 (patient must meet the criteria below)
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Ontario Limited Use criteria — code 548
Reason for Use code 548
- As adjunctive therapy in the treatment of patients with partial-onset seizures (POS) who have had an inadequate response or have significant intolerance to at least 2 other less costly anticonvulsant therapies (prior or current use); AND
- Patients are not receiving concurrent therapy with levetiracetam; AND
- Patients are under the care of a physician experienced in the treatment of epilepsy.
Note: Less costly anticonvulsant therapies may include the following:
Phenytoin, carbamazepine, gabapentin, lamotrigine, vigabatrin, topiramate, etc.
Coverage limit:
LU Authorization Period: Indefinite
1 brand, same coverage
Apo-Brivaracetam · DIN 02538679
Manufacturer: Apotex Inc.; listing date 2024-11-29
Health Canada: Marketed since 2024-09-10 · brand APO-BRIVARACETAM · ATC N03AX23 BRIVARACETAM · form Tablet · route Oral · ingredients BRIVARACETAM 10 MG · company Apotex inc · schedule Prescription
Check this DIN again · Health Canada product recordApo-Brivaracetam: Formulary list price $2.3760/unit (unit not stated in source; not the patient's cost)
Ministry pays: $2.3760 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=102737 · Verify on the e-Formulary ↗ (DIN 02538679)
Source record
DIN 02538679: Apo-Brivaracetam
Raw flags: sec12=Y, sec3=Y
Item: 281200177; group id 420; item number 1036; lccId 00312; manufacturer id APX
Source form: Tab; strength: 10mg
Recorded listing: Limited Use: paid only with a Reason for Use code and the criteria below
Source prices (unrounded): $2.3760; ministry $2.3760
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02538679
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=102737
Interchangeable products
Brivlera · DIN 02452936 · $2.3760
Shortage status: no shortage or discontinuation reported (checked 2026-09-13T08:10:21.292534+00:00); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02538679
Shortage record checked 2026-09-13T08:10:21.292534+00:00
Brivlera · DIN 02452936 · 10mg · tablet
Limited Use — Reason for Use code 548 requiredMarketed · checked 2026-09-02
Write on scriptLU code 548 (patient must meet the criteria below)
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Ontario Limited Use criteria — code 548
Reason for Use code 548
- As adjunctive therapy in the treatment of patients with partial-onset seizures (POS) who have had an inadequate response or have significant intolerance to at least 2 other less costly anticonvulsant therapies (prior or current use); AND
- Patients are not receiving concurrent therapy with levetiracetam; AND
- Patients are under the care of a physician experienced in the treatment of epilepsy.
Note: Less costly anticonvulsant therapies may include the following:
Phenytoin, carbamazepine, gabapentin, lamotrigine, vigabatrin, topiramate, etc.
Coverage limit:
LU Authorization Period: Indefinite
Savings card: RxHelp ONE lists Brivlera (read 2026-09-10) — brand-name savings card, free; cannot be combined with another card on the same claim.
(rxhelp.ca ↗)1 brand, same coverage
Brivlera · DIN 02452936
Manufacturer: UCB Canada Inc.; listing date 2018-12-21
Health Canada: Marketed since 2016-05-02 · brand BRIVLERA · ATC N03AX23 BRIVARACETAM · form Tablet · route Oral · ingredients BRIVARACETAM 10 MG · company Ucb canada inc · schedule Prescription
Check this DIN again · Health Canada product recordMinistry pays: $2.3760 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=93933 · Verify on the e-Formulary ↗ (DIN 02452936)
Source record
DIN 02452936: Brivlera
Raw flags: sec12=Y, sec3=Y
Item: 281200177; group id 420; item number 1036; lccId 00312; manufacturer id UCB
Source form: Tab; strength: 10mg
Recorded listing: Limited Use: paid only with a Reason for Use code and the criteria below
Source prices (unrounded): $4.3200; ministry $2.3760
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02452936
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=93933
Interchangeable products
Apo-Brivaracetam · DIN 02538679 · $2.3760
Shortage status: resolved shortage (ended 2020-06-02); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02452936
Shortage record checked 2026-09-13T08:10:21.292534+00:00
Apo-Brivaracetam · DIN 02538687 · 25mg · tablet
Limited Use — Reason for Use code 548 requiredMarketed · checked 2026-09-02
Write on scriptLU code 548 (patient must meet the criteria below)
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Ontario Limited Use criteria — code 548
Reason for Use code 548
- As adjunctive therapy in the treatment of patients with partial-onset seizures (POS) who have had an inadequate response or have significant intolerance to at least 2 other less costly anticonvulsant therapies (prior or current use); AND
- Patients are not receiving concurrent therapy with levetiracetam; AND
- Patients are under the care of a physician experienced in the treatment of epilepsy.
Note: Less costly anticonvulsant therapies may include the following:
Phenytoin, carbamazepine, gabapentin, lamotrigine, vigabatrin, topiramate, etc.
Coverage limit:
LU Authorization Period: Indefinite
1 brand, same coverage
Apo-Brivaracetam · DIN 02538687
Manufacturer: Apotex Inc.; listing date 2024-11-29
Health Canada: Marketed since 2024-09-10 · brand APO-BRIVARACETAM · ATC N03AX23 BRIVARACETAM · form Tablet · route Oral · ingredients BRIVARACETAM 25 MG · company Apotex inc · schedule Prescription
Check this DIN again · Health Canada product recordApo-Brivaracetam: Formulary list price $2.3760/unit (unit not stated in source; not the patient's cost)
Ministry pays: $2.3760 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=102739 · Verify on the e-Formulary ↗ (DIN 02538687)
Source record
DIN 02538687: Apo-Brivaracetam
Raw flags: sec12=Y, sec3=Y
Item: 281200178; group id 420; item number 1037; lccId 00312; manufacturer id APX
Source form: Tab; strength: 25mg
Recorded listing: Limited Use: paid only with a Reason for Use code and the criteria below
Source prices (unrounded): $2.3760; ministry $2.3760
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02538687
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=102739
Interchangeable products
Brivlera · DIN 02452944 · $2.3760
Shortage status: shortage reported ended 2026-04-02 (report last updated 2026-04-02); confirm supply with the pharmacy; reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02538687
Shortage record checked 2026-09-13T08:10:21.292534+00:00
Brivlera · DIN 02452944 · 25mg · tablet
Limited Use — Reason for Use code 548 requiredMarketed · checked 2026-09-02
Write on scriptLU code 548 (patient must meet the criteria below)
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Ontario Limited Use criteria — code 548
Reason for Use code 548
- As adjunctive therapy in the treatment of patients with partial-onset seizures (POS) who have had an inadequate response or have significant intolerance to at least 2 other less costly anticonvulsant therapies (prior or current use); AND
- Patients are not receiving concurrent therapy with levetiracetam; AND
- Patients are under the care of a physician experienced in the treatment of epilepsy.
Note: Less costly anticonvulsant therapies may include the following:
Phenytoin, carbamazepine, gabapentin, lamotrigine, vigabatrin, topiramate, etc.
Coverage limit:
LU Authorization Period: Indefinite
Savings card: RxHelp ONE lists Brivlera (read 2026-09-10) — brand-name savings card, free; cannot be combined with another card on the same claim.
(rxhelp.ca ↗)1 brand, same coverage
Brivlera · DIN 02452944
Manufacturer: UCB Canada Inc.; listing date 2018-12-21
Health Canada: Marketed since 2016-05-02 · brand BRIVLERA · ATC N03AX23 BRIVARACETAM · form Tablet · route Oral · ingredients BRIVARACETAM 25 MG · company Ucb canada inc · schedule Prescription
Check this DIN again · Health Canada product recordMinistry pays: $2.3760 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=93934 · Verify on the e-Formulary ↗ (DIN 02452944)
Source record
DIN 02452944: Brivlera
Raw flags: sec12=Y, sec3=Y
Item: 281200178; group id 420; item number 1037; lccId 00312; manufacturer id UCB
Source form: Tab; strength: 25mg
Recorded listing: Limited Use: paid only with a Reason for Use code and the criteria below
Source prices (unrounded): $4.3200; ministry $2.3760
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02452944
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=93934
Interchangeable products
Apo-Brivaracetam · DIN 02538687 · $2.3760
Shortage status: resolved shortage (ended 2020-06-08); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02452944
Shortage record checked 2026-09-13T08:10:21.292534+00:00
Apo-Brivaracetam · DIN 02538695 · 50mg · tablet
Limited Use — Reason for Use code 548 requiredMarketed · checked 2026-09-02
Write on scriptLU code 548 (patient must meet the criteria below)
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Ontario Limited Use criteria — code 548
Reason for Use code 548
- As adjunctive therapy in the treatment of patients with partial-onset seizures (POS) who have had an inadequate response or have significant intolerance to at least 2 other less costly anticonvulsant therapies (prior or current use); AND
- Patients are not receiving concurrent therapy with levetiracetam; AND
- Patients are under the care of a physician experienced in the treatment of epilepsy.
Note: Less costly anticonvulsant therapies may include the following:
Phenytoin, carbamazepine, gabapentin, lamotrigine, vigabatrin, topiramate, etc.
Coverage limit:
LU Authorization Period: Indefinite
Brand vs generic price
Lowest DBP recovery rule under medically necessary no-substitution claims:
6.2 Medically Necessary "No Substitution" Claims
The Side Effect Reporting Form will not have to be renewed. However, the
pharmacy must maintain a copy of the prescription that contains a direction that
there be no substitution and the required Health Canada Side Effect Reporting Form
(completed and signed by the prescriber). The prescriber must write “No
Substitution” or “No Sub” on renewal or subsequent new written prescriptions, and
indicate “No Substitution” on subsequent new oral prescriptions. The dispenser will
be reimbursed the DBP plus a mark-up and the lesser of the posted usual and
customary fee or the ODB dispensing fee minus the applicable ODB co-payment
amount. Where a completed Side Effect Reporting Form is not available at the
pharmacy during an inspection, the difference between the cost of the higher-cost
product and the lowest DBP listed for the interchangeable category will be
recovered.
(ontario.ca, Revision #17; 2026-08-03 ↗)
6.2 Medically Necessary "No Substitution" Claims
The Ministry will provide reimbursement of a higher-cost interchangeable product in
medically necessary circumstances where a patient has experienced a significant
adverse reaction with two (2) lower-cost interchangeable drug products, where
available. When a prescriber identifies a patient for which it is medically necessary
that a higher cost interchangeable product be provided, the prescriber must:
• Complete, sign and forward to the pharmacist a copy of the Health Canada
side effect reporting form for each lower-cost interchangeable drug product
trialed (Side Effect Reporting Form[s]); and
• Write “No Substitution” or “No Sub” on a written prescription or indicate “No
Substitution” to the pharmacist in the case of a verbal prescription.
The prescriber should keep a copy of the completed form in the patient’s record for
future use and reference.
In the case of a written prescription, when the pharmacist or dispensing physician
receives a prescription with the written notation “No Substitution” or “No Sub”,
reimbursement will be provided for the higher-cost interchangeable product only if
the prescription is accompanied by a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed.
This form must be completely filled out noting the details of the adverse reaction
and signed by the prescriber.
In the case of a verbal prescription, the prescriber must satisfy the operator of the
pharmacy or dispensing physician that a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed
has been completed and signed by the prescriber. A written record of this verbal
prescription and the completed Health Canada Side Effect Reporting Form must be
received by the pharmacy prior to claim submission.
Upon receipt, the pharmacist must:
• Fax, submit online or mail the completed and signed form to Health Canada’s
Canada Vigilance Program; and
• Retain his or her copy of the completed and signed Side Effect Reporting
Form.
(ontario.ca, Revision #17; 2026-08-03 ↗)1 brand, same coverage
Apo-Brivaracetam · DIN 02538695
Manufacturer: Apotex Inc.; listing date 2024-11-29
Health Canada: Marketed since 2024-09-10 · brand APO-BRIVARACETAM · ATC N03AX23 BRIVARACETAM · form Tablet · route Oral · ingredients BRIVARACETAM 50 MG · company Apotex inc · schedule Prescription
Check this DIN again · Health Canada product recordApo-Brivaracetam: Formulary list price $2.1600/unit (unit not stated in source; not the patient's cost)
Ministry pays: $2.1600 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=102740 · Verify on the e-Formulary ↗ (DIN 02538695)
Source record
DIN 02538695: Apo-Brivaracetam
Raw flags: sec12=Y, sec3=Y
Item: 281200179; group id 420; item number 1038; lccId 00312; manufacturer id APX
Source form: Tab; strength: 50mg
Recorded listing: Limited Use: paid only with a Reason for Use code and the criteria below
Source prices (unrounded): $2.1600; ministry $2.1600
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02538695
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=102740
Interchangeable products
Auro-Brivaracetam · DIN 02539292 · $2.1600
Brivlera · DIN 02452952 · $2.1600
Shortage status: active shortage (reported 2026-08-18, estimated to end 2026-09-18, last updated 2026-09-11); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02538695
Shortage record checked 2026-09-13T08:10:21.292534+00:00
Auro-Brivaracetam · DIN 02539292 · 50mg · tablet
Limited Use — Reason for Use code 548 requiredMarketed · checked 2026-09-02
Write on scriptLU code 548 (patient must meet the criteria below)
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Ontario Limited Use criteria — code 548
Reason for Use code 548
- As adjunctive therapy in the treatment of patients with partial-onset seizures (POS) who have had an inadequate response or have significant intolerance to at least 2 other less costly anticonvulsant therapies (prior or current use); AND
- Patients are not receiving concurrent therapy with levetiracetam; AND
- Patients are under the care of a physician experienced in the treatment of epilepsy.
Note: Less costly anticonvulsant therapies may include the following:
Phenytoin, carbamazepine, gabapentin, lamotrigine, vigabatrin, topiramate, etc.
Coverage limit:
LU Authorization Period: Indefinite
Brand vs generic price
Lowest DBP recovery rule under medically necessary no-substitution claims:
6.2 Medically Necessary "No Substitution" Claims
The Side Effect Reporting Form will not have to be renewed. However, the
pharmacy must maintain a copy of the prescription that contains a direction that
there be no substitution and the required Health Canada Side Effect Reporting Form
(completed and signed by the prescriber). The prescriber must write “No
Substitution” or “No Sub” on renewal or subsequent new written prescriptions, and
indicate “No Substitution” on subsequent new oral prescriptions. The dispenser will
be reimbursed the DBP plus a mark-up and the lesser of the posted usual and
customary fee or the ODB dispensing fee minus the applicable ODB co-payment
amount. Where a completed Side Effect Reporting Form is not available at the
pharmacy during an inspection, the difference between the cost of the higher-cost
product and the lowest DBP listed for the interchangeable category will be
recovered.
(ontario.ca, Revision #17; 2026-08-03 ↗)
6.2 Medically Necessary "No Substitution" Claims
The Ministry will provide reimbursement of a higher-cost interchangeable product in
medically necessary circumstances where a patient has experienced a significant
adverse reaction with two (2) lower-cost interchangeable drug products, where
available. When a prescriber identifies a patient for which it is medically necessary
that a higher cost interchangeable product be provided, the prescriber must:
• Complete, sign and forward to the pharmacist a copy of the Health Canada
side effect reporting form for each lower-cost interchangeable drug product
trialed (Side Effect Reporting Form[s]); and
• Write “No Substitution” or “No Sub” on a written prescription or indicate “No
Substitution” to the pharmacist in the case of a verbal prescription.
The prescriber should keep a copy of the completed form in the patient’s record for
future use and reference.
In the case of a written prescription, when the pharmacist or dispensing physician
receives a prescription with the written notation “No Substitution” or “No Sub”,
reimbursement will be provided for the higher-cost interchangeable product only if
the prescription is accompanied by a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed.
This form must be completely filled out noting the details of the adverse reaction
and signed by the prescriber.
In the case of a verbal prescription, the prescriber must satisfy the operator of the
pharmacy or dispensing physician that a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed
has been completed and signed by the prescriber. A written record of this verbal
prescription and the completed Health Canada Side Effect Reporting Form must be
received by the pharmacy prior to claim submission.
Upon receipt, the pharmacist must:
• Fax, submit online or mail the completed and signed form to Health Canada’s
Canada Vigilance Program; and
• Retain his or her copy of the completed and signed Side Effect Reporting
Form.
(ontario.ca, Revision #17; 2026-08-03 ↗)1 brand, same coverage
Auro-Brivaracetam · DIN 02539292
Manufacturer: Auro Pharma Inc.; listing date 2024-11-29
Health Canada: Marketed since 2024-09-12 · brand AURO-BRIVARACETAM · ATC N03AX23 BRIVARACETAM · form Tablet · route Oral · ingredients BRIVARACETAM 50 MG · company Auro pharma inc · schedule Prescription
Check this DIN again · Health Canada product recordAuro-Brivaracetam: Formulary list price $2.1600/unit (unit not stated in source; not the patient's cost)
Ministry pays: $2.1600 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=102793 · Verify on the e-Formulary ↗ (DIN 02539292)
Source record
DIN 02539292: Auro-Brivaracetam
Raw flags: sec12=Y, sec3=Y
Item: 281200179; group id 420; item number 1038; lccId 00312; manufacturer id AUR
Source form: Tab; strength: 50mg
Recorded listing: Limited Use: paid only with a Reason for Use code and the criteria below
Source prices (unrounded): $2.1600; ministry $2.1600
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02539292
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=102793
Interchangeable products
Apo-Brivaracetam · DIN 02538695 · $2.1600
Brivlera · DIN 02452952 · $2.1600
Shortage status: no shortage or discontinuation reported (checked 2026-09-13T08:10:21.292534+00:00); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02539292
Shortage record checked 2026-09-13T08:10:21.292534+00:00
Brivlera · DIN 02452952 · 50mg · tablet
Limited Use — Reason for Use code 548 requiredMarketed · checked 2026-09-02
Write on scriptLU code 548 (patient must meet the criteria below)
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Ontario Limited Use criteria — code 548
Reason for Use code 548
- As adjunctive therapy in the treatment of patients with partial-onset seizures (POS) who have had an inadequate response or have significant intolerance to at least 2 other less costly anticonvulsant therapies (prior or current use); AND
- Patients are not receiving concurrent therapy with levetiracetam; AND
- Patients are under the care of a physician experienced in the treatment of epilepsy.
Note: Less costly anticonvulsant therapies may include the following:
Phenytoin, carbamazepine, gabapentin, lamotrigine, vigabatrin, topiramate, etc.
Coverage limit:
LU Authorization Period: Indefinite
Savings card: RxHelp ONE lists Brivlera (read 2026-09-10) — brand-name savings card, free; cannot be combined with another card on the same claim.
(rxhelp.ca ↗)1 brand, same coverage
Brivlera · DIN 02452952
Manufacturer: UCB Canada Inc.; listing date 2018-12-21
Health Canada: Marketed since 2016-05-02 · brand BRIVLERA · ATC N03AX23 BRIVARACETAM · form Tablet · route Oral · ingredients BRIVARACETAM 50 MG · company Ucb canada inc · schedule Prescription
Check this DIN again · Health Canada product recordMinistry pays: $2.1600 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=93935 · Verify on the e-Formulary ↗ (DIN 02452952)
Source record
DIN 02452952: Brivlera
Raw flags: sec12=Y, sec3=Y
Item: 281200179; group id 420; item number 1038; lccId 00312; manufacturer id UCB
Source form: Tab; strength: 50mg
Recorded listing: Limited Use: paid only with a Reason for Use code and the criteria below
Source prices (unrounded): $4.3200; ministry $2.1600
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02452952
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=93935
Interchangeable products
Apo-Brivaracetam · DIN 02538695 · $2.1600
Auro-Brivaracetam · DIN 02539292 · $2.1600
Shortage status: no shortage or discontinuation reported (checked 2026-09-13T08:10:21.292534+00:00); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02452952
Shortage record checked 2026-09-13T08:10:21.292534+00:00
Apo-Brivaracetam · DIN 02538709 · 75mg · tablet
Limited Use — Reason for Use code 548 requiredMarketed · checked 2026-09-02
Write on scriptLU code 548 (patient must meet the criteria below)
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Ontario Limited Use criteria — code 548
Reason for Use code 548
- As adjunctive therapy in the treatment of patients with partial-onset seizures (POS) who have had an inadequate response or have significant intolerance to at least 2 other less costly anticonvulsant therapies (prior or current use); AND
- Patients are not receiving concurrent therapy with levetiracetam; AND
- Patients are under the care of a physician experienced in the treatment of epilepsy.
Note: Less costly anticonvulsant therapies may include the following:
Phenytoin, carbamazepine, gabapentin, lamotrigine, vigabatrin, topiramate, etc.
Coverage limit:
LU Authorization Period: Indefinite
1 brand, same coverage
Apo-Brivaracetam · DIN 02538709
Manufacturer: Apotex Inc.; listing date 2024-11-29
Health Canada: Marketed since 2024-09-10 · brand APO-BRIVARACETAM · ATC N03AX23 BRIVARACETAM · form Tablet · route Oral · ingredients BRIVARACETAM 75 MG · company Apotex inc · schedule Prescription
Check this DIN again · Health Canada product recordApo-Brivaracetam: Formulary list price $2.3760/unit (unit not stated in source; not the patient's cost)
Ministry pays: $2.3760 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=102741 · Verify on the e-Formulary ↗ (DIN 02538709)
Source record
DIN 02538709: Apo-Brivaracetam
Raw flags: sec12=Y, sec3=Y
Item: 281200180; group id 420; item number 1039; lccId 00312; manufacturer id APX
Source form: Tab; strength: 75mg
Recorded listing: Limited Use: paid only with a Reason for Use code and the criteria below
Source prices (unrounded): $2.3760; ministry $2.3760
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02538709
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=102741
Interchangeable products
Brivlera · DIN 02452960 · $2.3760
Shortage status: resolved shortage (ended 2026-03-12); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02538709
Shortage record checked 2026-09-13T08:10:21.292534+00:00
Brivlera · DIN 02452960 · 75mg · tablet
Limited Use — Reason for Use code 548 requiredMarketed · checked 2026-09-02
Write on scriptLU code 548 (patient must meet the criteria below)
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Ontario Limited Use criteria — code 548
Reason for Use code 548
- As adjunctive therapy in the treatment of patients with partial-onset seizures (POS) who have had an inadequate response or have significant intolerance to at least 2 other less costly anticonvulsant therapies (prior or current use); AND
- Patients are not receiving concurrent therapy with levetiracetam; AND
- Patients are under the care of a physician experienced in the treatment of epilepsy.
Note: Less costly anticonvulsant therapies may include the following:
Phenytoin, carbamazepine, gabapentin, lamotrigine, vigabatrin, topiramate, etc.
Coverage limit:
LU Authorization Period: Indefinite
Savings card: RxHelp ONE lists Brivlera (read 2026-09-10) — brand-name savings card, free; cannot be combined with another card on the same claim.
(rxhelp.ca ↗)1 brand, same coverage
Brivlera · DIN 02452960
Manufacturer: UCB Canada Inc.; listing date 2018-12-21
Health Canada: Marketed since 2016-05-02 · brand BRIVLERA · ATC N03AX23 BRIVARACETAM · form Tablet · route Oral · ingredients BRIVARACETAM 75 MG · company Ucb canada inc · schedule Prescription
Check this DIN again · Health Canada product recordMinistry pays: $2.3760 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=93936 · Verify on the e-Formulary ↗ (DIN 02452960)
Source record
DIN 02452960: Brivlera
Raw flags: sec12=Y, sec3=Y
Item: 281200180; group id 420; item number 1039; lccId 00312; manufacturer id UCB
Source form: Tab; strength: 75mg
Recorded listing: Limited Use: paid only with a Reason for Use code and the criteria below
Source prices (unrounded): $4.3200; ministry $2.3760
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02452960
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=93936
Interchangeable products
Apo-Brivaracetam · DIN 02538709 · $2.3760
Shortage status: no shortage or discontinuation reported (checked 2026-09-13T08:10:21.292534+00:00); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02452960
Shortage record checked 2026-09-13T08:10:21.292534+00:00
Apo-Brivaracetam · DIN 02538717 · 100mg · tablet
Limited Use — Reason for Use code 548 requiredMarketed · checked 2026-09-02
Write on scriptLU code 548 (patient must meet the criteria below)
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Ontario Limited Use criteria — code 548
Reason for Use code 548
- As adjunctive therapy in the treatment of patients with partial-onset seizures (POS) who have had an inadequate response or have significant intolerance to at least 2 other less costly anticonvulsant therapies (prior or current use); AND
- Patients are not receiving concurrent therapy with levetiracetam; AND
- Patients are under the care of a physician experienced in the treatment of epilepsy.
Note: Less costly anticonvulsant therapies may include the following:
Phenytoin, carbamazepine, gabapentin, lamotrigine, vigabatrin, topiramate, etc.
Coverage limit:
LU Authorization Period: Indefinite
Brand vs generic price
Lowest DBP recovery rule under medically necessary no-substitution claims:
6.2 Medically Necessary "No Substitution" Claims
The Side Effect Reporting Form will not have to be renewed. However, the
pharmacy must maintain a copy of the prescription that contains a direction that
there be no substitution and the required Health Canada Side Effect Reporting Form
(completed and signed by the prescriber). The prescriber must write “No
Substitution” or “No Sub” on renewal or subsequent new written prescriptions, and
indicate “No Substitution” on subsequent new oral prescriptions. The dispenser will
be reimbursed the DBP plus a mark-up and the lesser of the posted usual and
customary fee or the ODB dispensing fee minus the applicable ODB co-payment
amount. Where a completed Side Effect Reporting Form is not available at the
pharmacy during an inspection, the difference between the cost of the higher-cost
product and the lowest DBP listed for the interchangeable category will be
recovered.
(ontario.ca, Revision #17; 2026-08-03 ↗)
6.2 Medically Necessary "No Substitution" Claims
The Ministry will provide reimbursement of a higher-cost interchangeable product in
medically necessary circumstances where a patient has experienced a significant
adverse reaction with two (2) lower-cost interchangeable drug products, where
available. When a prescriber identifies a patient for which it is medically necessary
that a higher cost interchangeable product be provided, the prescriber must:
• Complete, sign and forward to the pharmacist a copy of the Health Canada
side effect reporting form for each lower-cost interchangeable drug product
trialed (Side Effect Reporting Form[s]); and
• Write “No Substitution” or “No Sub” on a written prescription or indicate “No
Substitution” to the pharmacist in the case of a verbal prescription.
The prescriber should keep a copy of the completed form in the patient’s record for
future use and reference.
In the case of a written prescription, when the pharmacist or dispensing physician
receives a prescription with the written notation “No Substitution” or “No Sub”,
reimbursement will be provided for the higher-cost interchangeable product only if
the prescription is accompanied by a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed.
This form must be completely filled out noting the details of the adverse reaction
and signed by the prescriber.
In the case of a verbal prescription, the prescriber must satisfy the operator of the
pharmacy or dispensing physician that a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed
has been completed and signed by the prescriber. A written record of this verbal
prescription and the completed Health Canada Side Effect Reporting Form must be
received by the pharmacy prior to claim submission.
Upon receipt, the pharmacist must:
• Fax, submit online or mail the completed and signed form to Health Canada’s
Canada Vigilance Program; and
• Retain his or her copy of the completed and signed Side Effect Reporting
Form.
(ontario.ca, Revision #17; 2026-08-03 ↗)1 brand, same coverage
Apo-Brivaracetam · DIN 02538717
Manufacturer: Apotex Inc.; listing date 2024-11-29
Health Canada: Marketed since 2024-09-10 · brand APO-BRIVARACETAM · ATC N03AX23 BRIVARACETAM · form Tablet · route Oral · ingredients BRIVARACETAM 100 MG · company Apotex inc · schedule Prescription
Check this DIN again · Health Canada product recordApo-Brivaracetam: Formulary list price $2.1600/unit (unit not stated in source; not the patient's cost)
Ministry pays: $2.1600 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=102742 · Verify on the e-Formulary ↗ (DIN 02538717)
Source record
DIN 02538717: Apo-Brivaracetam
Raw flags: sec12=Y, sec3=Y
Item: 281200181; group id 420; item number 1040; lccId 00312; manufacturer id APX
Source form: Tab; strength: 100mg
Recorded listing: Limited Use: paid only with a Reason for Use code and the criteria below
Source prices (unrounded): $2.1600; ministry $2.1600
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02538717
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=102742
Interchangeable products
Auro-Brivaracetam · DIN 02539306 · $2.1600
Brivlera · DIN 02452979 · $2.1600
Shortage status: resolved shortage (ended 2026-04-02); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02538717
Shortage record checked 2026-09-13T08:10:21.292534+00:00
Auro-Brivaracetam · DIN 02539306 · 100mg · tablet
Limited Use — Reason for Use code 548 requiredMarketed · checked 2026-09-02
Write on scriptLU code 548 (patient must meet the criteria below)
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Ontario Limited Use criteria — code 548
Reason for Use code 548
- As adjunctive therapy in the treatment of patients with partial-onset seizures (POS) who have had an inadequate response or have significant intolerance to at least 2 other less costly anticonvulsant therapies (prior or current use); AND
- Patients are not receiving concurrent therapy with levetiracetam; AND
- Patients are under the care of a physician experienced in the treatment of epilepsy.
Note: Less costly anticonvulsant therapies may include the following:
Phenytoin, carbamazepine, gabapentin, lamotrigine, vigabatrin, topiramate, etc.
Coverage limit:
LU Authorization Period: Indefinite
Brand vs generic price
Lowest DBP recovery rule under medically necessary no-substitution claims:
6.2 Medically Necessary "No Substitution" Claims
The Side Effect Reporting Form will not have to be renewed. However, the
pharmacy must maintain a copy of the prescription that contains a direction that
there be no substitution and the required Health Canada Side Effect Reporting Form
(completed and signed by the prescriber). The prescriber must write “No
Substitution” or “No Sub” on renewal or subsequent new written prescriptions, and
indicate “No Substitution” on subsequent new oral prescriptions. The dispenser will
be reimbursed the DBP plus a mark-up and the lesser of the posted usual and
customary fee or the ODB dispensing fee minus the applicable ODB co-payment
amount. Where a completed Side Effect Reporting Form is not available at the
pharmacy during an inspection, the difference between the cost of the higher-cost
product and the lowest DBP listed for the interchangeable category will be
recovered.
(ontario.ca, Revision #17; 2026-08-03 ↗)
6.2 Medically Necessary "No Substitution" Claims
The Ministry will provide reimbursement of a higher-cost interchangeable product in
medically necessary circumstances where a patient has experienced a significant
adverse reaction with two (2) lower-cost interchangeable drug products, where
available. When a prescriber identifies a patient for which it is medically necessary
that a higher cost interchangeable product be provided, the prescriber must:
• Complete, sign and forward to the pharmacist a copy of the Health Canada
side effect reporting form for each lower-cost interchangeable drug product
trialed (Side Effect Reporting Form[s]); and
• Write “No Substitution” or “No Sub” on a written prescription or indicate “No
Substitution” to the pharmacist in the case of a verbal prescription.
The prescriber should keep a copy of the completed form in the patient’s record for
future use and reference.
In the case of a written prescription, when the pharmacist or dispensing physician
receives a prescription with the written notation “No Substitution” or “No Sub”,
reimbursement will be provided for the higher-cost interchangeable product only if
the prescription is accompanied by a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed.
This form must be completely filled out noting the details of the adverse reaction
and signed by the prescriber.
In the case of a verbal prescription, the prescriber must satisfy the operator of the
pharmacy or dispensing physician that a completed Health Canada Side Effect
Reporting Form for each of the lower-cost interchangeable drug products trialed
has been completed and signed by the prescriber. A written record of this verbal
prescription and the completed Health Canada Side Effect Reporting Form must be
received by the pharmacy prior to claim submission.
Upon receipt, the pharmacist must:
• Fax, submit online or mail the completed and signed form to Health Canada’s
Canada Vigilance Program; and
• Retain his or her copy of the completed and signed Side Effect Reporting
Form.
(ontario.ca, Revision #17; 2026-08-03 ↗)1 brand, same coverage
Auro-Brivaracetam · DIN 02539306
Manufacturer: Auro Pharma Inc.; listing date 2024-11-29
Health Canada: Marketed since 2024-09-12 · brand AURO-BRIVARACETAM · ATC N03AX23 BRIVARACETAM · form Tablet · route Oral · ingredients BRIVARACETAM 100 MG · company Auro pharma inc · schedule Prescription
Check this DIN again · Health Canada product recordAuro-Brivaracetam: Formulary list price $2.1600/unit (unit not stated in source; not the patient's cost)
Ministry pays: $2.1600 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=102794 · Verify on the e-Formulary ↗ (DIN 02539306)
Source record
DIN 02539306: Auro-Brivaracetam
Raw flags: sec12=Y, sec3=Y
Item: 281200181; group id 420; item number 1040; lccId 00312; manufacturer id AUR
Source form: Tab; strength: 100mg
Recorded listing: Limited Use: paid only with a Reason for Use code and the criteria below
Source prices (unrounded): $2.1600; ministry $2.1600
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02539306
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=102794
Interchangeable products
Apo-Brivaracetam · DIN 02538717 · $2.1600
Brivlera · DIN 02452979 · $2.1600
Shortage status: no shortage or discontinuation reported (checked 2026-09-13T08:10:21.292534+00:00); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02539306
Shortage record checked 2026-09-13T08:10:21.292534+00:00
Brivlera · DIN 02452979 · 100mg · tablet
Limited Use — Reason for Use code 548 requiredMarketed · checked 2026-09-02
Write on scriptLU code 548 (patient must meet the criteria below)
Private plan unknown: ask. If yes, check its coverage and payer coordination; if no, see the public routes below.
Ontario Limited Use criteria — code 548
Reason for Use code 548
- As adjunctive therapy in the treatment of patients with partial-onset seizures (POS) who have had an inadequate response or have significant intolerance to at least 2 other less costly anticonvulsant therapies (prior or current use); AND
- Patients are not receiving concurrent therapy with levetiracetam; AND
- Patients are under the care of a physician experienced in the treatment of epilepsy.
Note: Less costly anticonvulsant therapies may include the following:
Phenytoin, carbamazepine, gabapentin, lamotrigine, vigabatrin, topiramate, etc.
Coverage limit:
LU Authorization Period: Indefinite
Savings card: RxHelp ONE lists Brivlera (read 2026-09-10) — brand-name savings card, free; cannot be combined with another card on the same claim.
(rxhelp.ca ↗)1 brand, same coverage
Brivlera · DIN 02452979
Manufacturer: UCB Canada Inc.; listing date 2018-12-21
Health Canada: Marketed since 2016-05-02 · brand BRIVLERA · ATC N03AX23 BRIVARACETAM · form Tablet · route Oral · ingredients BRIVARACETAM 100 MG · company Ucb canada inc · schedule Prescription
Check this DIN again · Health Canada product recordMinistry pays: $2.1600 per source unit.
Source explanation: The formulary price is what ODB pays; the cash price at the counter is set by the pharmacy.
Formulary data: Ontario extract of Aug 26, 2026 · Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=93937 · Verify on the e-Formulary ↗ (DIN 02452979)
Source record
DIN 02452979: Brivlera
Raw flags: sec12=Y, sec3=Y
Item: 281200181; group id 420; item number 1040; lccId 00312; manufacturer id UCB
Source form: Tab; strength: 100mg
Recorded listing: Limited Use: paid only with a Reason for Use code and the criteria below
Source prices (unrounded): $4.3200; ministry $2.1600
Source: ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26 DIN=02452979
Health Canada DPD extract of Sep 2, 2026 (Open Government Licence – Canada) · https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=93937
Interchangeable products
Apo-Brivaracetam · DIN 02538717 · $2.1600
Auro-Brivaracetam · DIN 02539306 · $2.1600
Shortage status: resolved shortage (ended 2018-05-04); reports as of 2026-09-13T08:10:21.292534+00:00 (Health Product Shortages Canada)
Source: https://healthproductshortages.ca/search?term=02452979
Shortage record checked 2026-09-13T08:10:21.292534+00:00
Other drugs in the same formulary class (28:12 Anticonvulsants) and how they are covered
Matched class: 28:12 Anticonvulsants
Drug-class inventory only. Lists recorded Ontario formulary products, not every Canadian medication; does not recommend treatment.
Covered without a code on the Ontario formulary: CLONAZEPAM, DIVALPROEX SODIUM, ETHOSUXIMIDE, LAMOTRIGINE, VALPROATE SODIUM
Some products covered without a code (check the product listing): CARBAMAZEPINE, GABAPENTIN, PHENYTOIN (DIPHENYLHYDANTOIN), PHENYTOIN (DIPHENYLHYDANTOIN) SODIUM, PREGABALIN, PRIMIDONE, TOPIRAMATE, VALPROIC ACID
28:12 Anticonvulsants
· 28 products · General benefit · strengths: 25mg, 100mg, 150mg · Tab
· 54 products ·
Limited Use, codes 321 (2), Off-Formulary Interchangeable, not an ODB benefit (3), General benefit (49) · strengths: 15mg, 25mg, 50mg, 100mg, 200mg · Sprinkle Cap, Tab
· 9 products ·
Limited Use, codes 719 · strengths: 12.5mg, 25mg, 50mg, 100mg, 150mg, 200mg, 12.5mg & 25mg, 50mg & 100mg, 150mg & 200mg · Tab, Tab - (Starter Kit)
· 44 products ·
Limited Use, codes 430 · strengths: 50mg, 100mg, 150mg, 200mg · Tab
· 49 products ·
Limited Use, codes 640, 705 (3),
Limited Use, codes 473 (46) · strengths: 100mg/mL, 250mg, 500mg, 750mg, 1000mg · Oral Sol, Tab
· 12 products ·
Limited Use, codes 430, 564 · strengths: 2mg, 4mg, 6mg, 8mg, 10mg, 12mg · Tab
· 15 products · Listed, not a benefit (3), General benefit (6), Temporary benefit (2),
Limited Use, codes 67 (4) · strengths: 100mg, 200mg, 400mg, 100mg/5mL · Chew Tab, ER Tab, LA Tab, Oral Susp, Tab
· 9 products · General benefit · strengths: 0.5mg, 2mg · Tab
· 9 products · General benefit · strengths: 125mg, 250mg, 500mg · Ent Tab
· 4 products · General benefit · strengths: 250mg, 50mg/mL · Cap, O/L
· 4 products · General benefit; DIN status E (meaning unconfirmed); confirm discontinuation/availability with Health Canada (2), General benefit (2) · strengths: 6mg/mL, 25mg/mL, 50mg · O/L, Tab
· 4 products · General benefit (3),
Limited Use, codes 481, 657 (1) · strengths: 30mg, 100mg, 50mg/mL · Cap, Inj Sol (Preservative Free)
Source: formulary-ed43-front-matter.txt Part V; ODB odb-formulary-ed43-extract-2026-08-26.xml extract_date=2026-08-26; class 28:12
and 11 more
Full class listing
Related classes: 28:08 Analgesics, 28:10 Opiate Antagonists, 28:16 Psychotherapeutic Agents, 28:20 C.N.S. Stimulants, 28:24 Sedatives and Hypnotics, 28:36 Antiparkinsonian Agents, 28:92 Miscellaneous Central Nervous System Drugs
Same formulary class, not same indication: class membership alone does not establish equivalent uses.